Effects of perinatal exposure to low doses of cadmium or methylmercury on thyroid hormone metabolism in metallothionein-deficient mouse neonates

Toxicology

Volumn 228, Issue 1, 2006, Pages 77-84

  Mori, Kouki ^a   Yoshida, Katsumi ^b   Hoshikawa, Saeko ^a   Ito, Sadayoshi ^a   Yoshida, Minoru ^c   Satoh, Masahiko ^d,e   Watanabe, Chiho ^f  

^a TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b TOHOKU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c ST MARIANNA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d GIFU PHARMACEUTICAL UNIVERSITY   (Japan)

^e AICHI GAKUIN UNIVERSITY   (Japan)

^f UNIVERSITY OF TOKYO   (Japan)

Author keywords

Brain development; Cadmium; Iodothyronine deiodinase; Metallothionein; Methylmercury; Thyroid hormone

Indexed keywords

BRAIN ENZYME; CADMIUM; LIVER ENZYME; METALLOTHIONEIN I; METALLOTHIONEIN II; METHYLMERCURY; THYROID HORMONE; THYROXINE; THYROXINE DEIODINASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN; BRAIN DEVELOPMENT; CONCENTRATION RESPONSE; CONTROLLED STUDY; DEIODINATION; DOSE RESPONSE; ENZYME ACTIVITY; ENZYME BLOOD LEVEL; FEMALE; GENOTYPE; GESTATIONAL AGE; LIVER; MALE; MOUSE; NEWBORN; NONHUMAN; PERINATAL DRUG EXPOSURE; PERINATAL PERIOD; PRIORITY JOURNAL; PROTEIN DEFICIENCY; SERUM; THYROID HORMONE METABOLISM; THYROXINE BLOOD LEVEL; WILD TYPE;

ADMINISTRATION, ORAL; ANIMALS; ANIMALS, NEWBORN; BRAIN; CADMIUM; DOSE-RESPONSE RELATIONSHIP, DRUG; ENVIRONMENTAL POLLUTANTS; FEMALE; IODIDE PEROXIDASE; LIVER; MALE; MATERNAL EXPOSURE; METALLOTHIONEIN; METHYLMERCURY COMPOUNDS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PREGNANCY; THYROID GLAND; THYROID HORMONES;

EID: 33749594731     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2006.08.017     Document Type: Article

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