In utero methylmercury exposure differentially affects the activities of selenoenzymes in the fetal mouse brain

Environmental Research

Volumn 80, Issue 3, 1999, Pages 208-214

  Watanabe, Chiho ^a,b   Yoshida, Katsumi ^a   Kasanuma, Yuichi ^a   Kun, Yin ^a   Satoh, Hiroshi ^a  

^a TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

Author keywords

Iodothyronine deiodinases; Methylmercury; Mice; Prenatal exposure; Selenium

Indexed keywords

GLUTATHIONE PEROXIDASE; LIOTHYRONINE; METHYLMERCURY; THYROXINE; THYROXINE DEIODINASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN; BRAIN DEVELOPMENT; BRAIN LEVEL; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME INHIBITION; ENZYME LOCALIZATION; FEMALE; FETOTOXICITY; LIOTHYRONINE BLOOD LEVEL; NONHUMAN; PLACENTA; PRENATAL EXPOSURE; PRIORITY JOURNAL; THYROXINE BLOOD LEVEL;

EID: 0032918607     PISSN: 00139351     EISSN: None     Source Type: Journal    
DOI: 10.1006/enrs.1998.3889     Document Type: Article

References (51)

1. Akagi, H., and Nishimura, H. (1991). Speciation of mercury in the environment. In "Advances in Mercury Toxicology." (T. Suzuki, N. Imura and T. Clarkson Eds.), pp. 53-76. Plenum, New York.
2. Beamer, W., and Cresswell, L. (1982). Defective thyroid ontogenesis in fetal hypothyroid (hyt/hyt) mice. Anat. Rec. 202, 387-393.
3. Berry, M. J., Banu, L., and Larsen, P. R. (1991). Type I iodothyronine deiodinase is a selenocysteine-containing enzyme. Nature 349, 438-440.
4. Blum, J., and Fridovich, I. (1985), Inactivation of glutathione peroxidase by Superoxide radical. Archiv. Biochem. Biophys. 240, 500-508.
5. Burrow, G., Fisher, D., and Larsen, P. (1994). Maternal and fetal thyroid function. N. Engl. J. Med. 331, 1072-1078.
6. Cagiano, R., De Salvia, M., Renna, G., Tortella, E., Braghiroli, D., Parenti, C., Zanoli, P., Baraldi, M., Annau, Z., and Cuomo, V. (1990). Evidence that exposure to methylmercury during gestation induces behavioral and neurochemical changes in offspring of rats. Neurotoxicol. Teratol. 12, 23-28.
7. Castano, A., Ayala, A., Rodriguez-Gomez, J., de la Cruz, C., Cano, R., and Machado, A. (1995). Increase in dopamine turnover and tyrosine hydroxylase enzyme in hippocampus of rats fed on low selenium diet. J. Neurosci. Res. 42, 684-691.
8. Castano, A., Cano, J., and Machado, A. (1993). Low selenium diet affects monoamine turnover differentially in substantia nigra and striatum. J. Neurochem. 61, 1302-1307.
9. Chang, L., and Suber, R. (1982). Protective effect of selenium on methylmercury toxicity: A possible mechanism. Bull. Environ. Contam. Toxicol. 29, 285-289.
10. Chanoine, J.-P., Alex, S., Stone, S., Fang, S., Veronikis, I., Leonard, J., and Braverman, L. (1993). Placental 5-deiodinase activity and fetal thyroid hormone economy are unaffected by selenium deficiency in the rat. Pediatr. Res. 34, 288-292.
11. Croteau, W., Davey, J., Galton, V., and St. Germain, D. (1996). Cloning of the mammalian type II iodothyronine deiodinase. J. Clin. Invest. 98, 405-417.
12. Deussault, J., and Ruel, J. (1987). Thyroid hormones and brain development. Annu. Rev. Physiol. 49, 321-334.
13. Enrique Silva, J., and Matthews, P. (1984). Production rates and turnover of triiodothyronine in rat developing cerebral cortex and cerebellum. J. Clin. Invest. 74, 1035-1049.
14. Fredriksson, A., Gardlund, A. T., Bergman, K., Oskarsson, A., Ohlin, B., Danielsson, B., and Archer, T. (1993). Effects of maternal dietary supplementation with selenite on the postnatal development of rat offspring exposed to methyl mercury in utero. Pharmacol. Toxicol. 72, 377-382.
15. Gould, E., Woolley, C., and McEwen, B. (1991). The hippocampal formation: Morphological changes induced by thyroid, gonadal and adrenal hormones. Psychoneuroendocrinology 16, 67-84.
16. Grandjean, P., and Weihe, P. (1993). Neurobehavioral effects of intrauterine mercury exposure: Potential sources of bias. Environ. Res. 61, 176-183.
17. Hirota, Y. (1986). Effect of methylmercury on the activity of glutathione peroxidase in rat liver. Am. Ind. Hyg. Assoc. J. 47, 556-558.
18. Hirota, Y., Yamaguchi, S., Shimojoh, N., and Sano, K. (1980). Inhibitory effect of methylmercury on the activity of glutathione peroxidase. Toxicol. Appl. Pharmacol. 53, 174-176.
19. Imura, N., and Naganuma, A. (1991). Possible mechanism of detoxifying effect of selenium on the toxicity of mercury compounds. In "Advances in Mercury Toxicology" (T. Suzuki, N. Imura, and T. Clarkson, Eds.), pp. 275-288. Plenum, New York.
20. Itagaki, Y., Yoshida, K., Ikeda, H., Kaise, K., Kaise, N., Yamamoto, M., Sakurada, T., and Yoshinaga, K. (1990). Thyroxine 5′-deiodinase in human anterior pituitary tumors. J. Clin. Endocrinol. Metab. 71, 340-344.
21. Kabuto, M. (1986). Acute endocrine effects of a single administration of methylmercury chloride (MMC) in rats. Endocr. Jpn. 33, 683-690.
22. Kaplan, M., and Yaskoski, K. (1981). Maturational petterns of iodothyronine phenolic and throsyl ring deiodinase activities in rat cerebrum, cerebellum, and hypothalamus. J. Clin. Invest. 67, 1208-1214.
23. Kawada, J., Nishida, M., Yoshimura, Y., and Mitani, K. (1980). Effects of organic and inorganic mercurials on thyroidal functions. J. Pharmaco-dyn. 3, 149-159.
24. Kohrle, J. (1996). Thyroid hormone deiodinases - A selenoenzyme family acting as gate keepers to thyroid hormone action. Acta Med. Austriaca 23, 17-30.
25. Koopdonk-Kool, J. M., de Vijlder, J. J., Veenboer, G. J., Ris-Stalpers, C., Kok, J. H., Vulsma, T., Boer, K., and Visser, T. J. (1996). Type II and type III deiodinase activity in human placenta as a function of gestational age. J. Clin. Endocrinol. Metab. 81, 2154-2158.
26. LeBel, C., Ali, S., McKee, M., and Bondy, S. (1990). Organometal-induced increases in oxygen reactive species: The potential of 2′,7′-dichlorofluorescin diacetate as an index of neurotoxic damage. Toxicol. Appl. Pharmacol. 104, 17-24.
27. Lowry, O. H., Resebrough, N. H., Farr, A. L., and Randall, R. J. (1951). Protein measurement with the folin phenol reagent. J. Biol. Chem. 193, 265-275.
28. Meinhold, H., Campos-Barros, A., and Behne, D. (1992). Effects of selenium and iodine deficiency on iodothyronine deiodinases in brain, thyroid and peripheral tissue. Acta Med. Austriaca 19, 8-12.
29. Mirochnitchenko, O., Palnitkar, U., Philbert, M., and Inouye, M. (1995). Thermosensitive phenotype of transgenic mice over-producing human glutathione peroxidases. Proc. Natl. Acad. Sci. USA 92, 8120-8124.
30. Mori, K., Yoshida, K., Kaise, K., Kaise, N., Fukuzawa, H., Kikuchi, K., Abe, K., and Yoshinaga, K. (1993). Inhibition of placental thyroxine 5-deiodinase activity decreases amniotic fluid concentration of 3,3′,5′-triiodothyronine in rat. Endocrin. J. 40, 405-412.
31. Mortimer, R. H., Galligan, J. P., Cannell, G. R., Addison, R. S., and Roberts, M. S. (1996). Maternal to fetal thyroxine transmission in the human term placenta is limited by inner ring deiodination. J. Clin. Endocrinol. Metab. 81, 2247-2249.
32. Nishikido, N., Furuyashiki, K., Naganuma, A., Suzuki, T., and Imura, H. (1987). Maternal selenium deficiency enhances the fetolethal toxicity of methyl mercury. Toxicol. Appl. Pharmacol. 88, 322-328.
33. O'Kusky, J., Radke, J., and Vincent, S. (1988). Methylmercury-induced movement and postural disorders in developing rat: Loss of somatostatin-immunoreactive interneurons in the striatum. Dev. Brain Res. 40, 11-23.
34. Olanow, C. (1993). A radical hypothesis for neurodegeneration. Trends Neurosci. 16, 439-444.
35. Ozolines, T., Siksay, L., and Wells, P. (1996). Modulation of embryonic glutathione peroxidase activity and phenytoin teratogenicity by dietary deprivation of selinium in CD-1 mice. J. Pharamacol. Exp. Ther. 277, 945-953.
36. Paglia, D. E., and Valentine, W. N. (1967). Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase in developing rat brain. J. Lab. Clin. Med. 70, 158-169.
37. Pavlides, C., Westlind-Danielsson, A., Nyborg, H., and McEwen, B. (1991). Neonatal hyperthyroidism disrupts hippocampal LTP and spatial learning. Exp. Brain Res. 85, 559-564.
38. Pellmar, T., Gilman, S., Keyser, D., Lee, K., Lepinski, D., Livengood, D., and Myers Jr., L. (1994). Reactive oxygen species on neural transmission. Ann. NY Acad. Sci. 738, 121-129.
39. Porterneid, S., and Hendrich, C. (1993). The role of thyroid hormones in prenatal and neonatal neurological development - Current perspectives. Endocrinol. Rev. 14, 94-106.
40. Ramauge, M., Pallud, S., Esfandiari, A., Gavaret, J.-M., Lennon, A.-M., Pierre, M., and Courtin, F. (1996). Evidence that type III iodothyronine deiodinase in rat astrocyte is a selenoprotein. Endocrinology 137, 3021-3025.
41. Salvatore, D., Low, S., Berry, M., Maia, A., Harney, J., Croteau, W., St. Germain, D., and Larsen, P. (1995). Type 3 iodothyronine deiodinase: Cloning, in vitro expression, and functional analysis of the placental selenoenzyme. J. Clin. Invest. 96, 2421-2430.
42. Su, M.-Q., and Okita, G. (1976). Behavioral effects on the progeny of mice treated with methylmercury. Toxicol. Appl. Pharmacol. 38, 195-205.
43. Visser, T., Leonard, J., Kaplan, M., and Larsen, P. (1982). Kinetic evidence suggesting two mechanism for iodothyronine 5′-deiodination in rat cerebral cortex. Proc. Natl. Acad. Sci. USA 79.
44. Visser, T., and Schoenmakers, C. (1992). Characteristics of type III iodothyronine deiodinase. Acta Med. Austr. 19, 18-21.
45. Wang, Y., and Walsh, S. (1996). Antioxidant activities and mRNA expression of Superoxide dismutase, catalase, and glutathione perioixdase in normal and preeclamptic placentas. J. Soc. Gynecol. Invest. 3, 179-184.
46. +-induced release of dopamine in the striatum of the mice. Neurosci. Lett. 236, 49-52.
47. Watanabe, C., and Satoh, H. (1994). Brain selenium status and behavioral development in selenium-deficient preweanling mice. Physiol. Behav. 56, 927-932.
48. Watanabe, C., and Satoh, H. (1995). Effects of prolonged selenium deficiency on open field behavior and Morris water maze performance in mice. Pharmacol. Biochem. Behav. 51, 747-752.
49. Watkinson, J. (1966). Fluorometric determination of selenium in biological material with 2,3-diaminonaphthlalene. Anal. Chem. 38, 92-97.
50. Yee, S., and Choi, B. (1994). Methylmercury poisoning induces oxidative stress in the mouse brain. Exp. Mol. Pathol. 60, 188-196.
51. Yin, K., Watanabe, C., Inaba, H., and Satoh, H. (1997). Growth and behavioral changes in mice prenatally exposed to methylmercury and heat. Neurotoxicol. Teratol. 19, 65-71.