Moderate exercise and chronic stress produce counteractive effects on different areas of the brain by acting through various neurotransmitter receptor subtypes: A hypothesis

Theoretical Biology and Medical Modelling

Volumn 3, Issue , 2006, Pages

  Sarbadhikari, Suptendra N ^a   Saha, Asit K ^b  

^a AMRITA UNIVERSITY   (India)

^b UNIVERSITY OF SOUTH AUSTRALIA   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

5,7 DIHYDROXYTRYPTAMINE; DOPAMINE; NEUROTRANSMITTER RECEPTOR; NORADRENALIN; SEROTONIN ANTAGONIST; ADRENERGIC RECEPTOR; DOPAMINE RECEPTOR; SEROTONIN RECEPTOR;

AFFECT; ARTICLE; BRAIN FUNCTION; CHAOS THEORY; COGNITION; DEPRESSION; EXERCISE; HEMISPHERIC DOMINANCE; MEDICAL LITERATURE; NONLINEAR SYSTEM; PARAMETERS OF MEASUREMENT AND ANALYSIS; STRESS; BRAIN; HUMAN; MENTAL STRESS; PATHOPHYSIOLOGY; PHYSIOLOGY; PSYCHOLOGY;

BRAIN; DEPRESSION; EXERCISE; FUNCTIONAL LATERALITY; HUMANS; NONLINEAR DYNAMICS; RECEPTORS, ADRENERGIC; RECEPTORS, DOPAMINE; RECEPTORS, SEROTONIN; STRESS, PSYCHOLOGICAL;

EID: 33749591906     PISSN: 17424682     EISSN: 17424682     Source Type: Journal    
DOI: 10.1186/1742-4682-3-33     Document Type: Article

References (68)

1. Sarbadhikari SN: Neural network aided analysis of electrophysiological signals from the brain of an animal model of depression subjected to chronic physical exercise. In PhD Thesis Banaras Hindu University, Varanasi, India; 1995.
2. Mandal MK, Asthana H, Pandey R, Sarbadhikari S: Cerebral laterality in affect and affective illness: A review. Journal of Psychology 1996, 130:447-459.
3. Yurgelun-Todd DA, Ross AJ: Functional magnetic resonance imaging studies in bipolar disorder. CNS Spectrums 2006, 11:287-297.
4. Mastorakos G, Pavlatou M: Exercise as a stress model and the interplay between the hypothalamus-pituitary-adrenal and the hypothalamus-pituitary- thyroid axes. Hormone and Metabolic Research 2005, 37:577-584.
5. Atchley RA, Ilardi SS, Enloe A: Hemispheric asymmetry in the processing of emotional content in word meanings: the effect of current and past depression. Brain and Language 2003, 84:105-119.
6. Neveu PJ, Merlot E: Cytokine stress responses depend on lateralization in mice. Stress 2003, 6:5-9.
7. Toro MG, Ruiz JS, Talavera JA, Blanco C: Chaos theories and therapeutic commonalities among depression, Parkinson's disease, and cardiac arrhythmias. Comprehensive Psychiatry 1999, 40:238-244.
8. Levine DS, Brown VR, Shirey VT, Eds: Oscillations in Neural Systems. Mahwah, New Jersey: Lawrence Erlbaum Associates; 2000.
9. Thomasson N, Pezard L, Allilaire J-F, Renault B, Martinerie J: Nonlinear EEG changes associated with clinical improvement in depressed patients. Nonlinear Dynamics, Psychology and Life Sciences 2000, 4:203-218.
10. Jeong J: Nonlinear dynamics of EEG in Alzheimer's disease. Drug Development Research 2002, 56:57-66.
11. Petruzzello SJ, Hall EE, Ekkekakis P: Regional brain activation as a biological marker of affective responsivity to acute exercise: influence of fitness. Psychophysiology 2001, 38:99-106.
12. Kyriazis M: Practical applications of chaos theory to the modulation of human ageing: nature prefers chaos to regularity. Biogerontology 2003, 4:75-90.
13. Sarbadhikari SN, Chakrabarty K: Chaos in the brain: a short review alluding to epilepsy, depression, exercise and lateralization. Medical Engineering & Physics 2001, 23:445-455.
14. Glass L: Synchronization and rhythmic processes in Physiology. Nature 2001, 410:277-284.
15. Savi MA: Chaos and Order in Biomedical Rhythms. Journal of the Brazilian Society of Mechanical Science and Engineering 2005, XXVII:157-169.
16. Tecott LH: Monoamine neurotransmitters. In Kaplan & Sadock's Comprehensive Textbook of Psychiatry Volume Ch 1.4. 7th edition. Edited by: Sadock BJ, Sadock VA. Lippincott Williams & Wilkins; 2000:41-50.
17. Pediconi MF, Roccamo de Fernandez AM, Barrantes FJ: Asymmetric distribution and down-regulation of the muscarinic acetylcholine receptor in rat cerebral cortex. Neurochemical Research 1993, 18:565-72.
18. Bortolozzi A, Duffard R, de Duffard AM: Asymmetrical development of the monoamine systems in 2,4-dichlorophenoxyacetic acid treated rats. Neurotoxicology 2003, 24:149-157.
19. Xu ZC, Ling G, Sahr RN, Neal-Beliveau BS: Asymmetrical changes of dopamine receptors in the striatum after unilateral dopamine depletion. Brain Research 2005, 1038:163-70.
20. Fukumoto T, Kema IP, Levin M: Serotonin signaling is a very early step in patterning of the left-right axis in chick and frog embryos. Current Biology 2005, 15:794-803.
21. Larisch R, Meyer W, Klimke A, Kehren F, Vosberg H, Muller-Gartner HW: Left-right asymmetry of striatal dopamine D2 receptors. Nuclear Medicine Communications 1998, 19:781-787.
22. Shirakawa O, Kitamura N, Lin XH, Hashimoto T, Maeda K: Abnormal neurochemical asymmetry in the temporal lobe of schizophrenia. Progress in Neuro-Psychopharmacology and Biological Psychiatry 2001, 25:867-877.
23. Cotman CW, Engesser-Cesar C: Exercise enhances and protects brain function. Exercise Sport Science Review 2002, 30:75-79.
24. Garoflos E, Stamatakis A, Mantelas A, Philippidis H, Stylianopoulou F: Cellular mechanisms underlying an effect of "early handling" on pCREB and BDNF in the neonatal rat hippocampus. Brain Research 2005, 1052:187-195.
25. Shenal BV, Harrison DW, Demaree HA: The neuropsychology of depression: a literature review and preliminary model. Neuropsychology Review 2003, 13:33-42.
26. Sarbadhikari SN: Depression, Dementia and Dexterity: In Search of a Denominator. In Depression and Dementia: Progress in Brain Research, Clinical Applications and Future Trends Volume Chapter 3. Edited by: Sarbadhikari SN. Nova biomedical, New York; 2005:55-83.
27. Sarbadhikari SN: Balancing the Brain Activity: Putative Links between Epileptic, Cognitive and Affective Disorders. In Trends in Epilepsy Research Volume Chapter 5. Edited by: Benjamin SM. Nova Biomedical, New York; 2005:93-150.
28. Radak Z, Chung HY, Goto S: Exercise and hormesis: oxidative stress-related adaptation for successful aging. Biogerontology 2005, 6:71-75.
29. Di Mascio M, Di Giovanni G, Di Matteo V, Esposito E: Decreased chaos of midbrain dopaminergic neurons after serotonin denervation. Neuroscience 1999, 92:237-243.
30. Hoffman RE, Shi WX, Bunney BS: Anatomic basis of sequence-dependent predictability exhibited by nigral dopamine neuron firing patterns. Synapse 2001, 39:133-138.
31. Fell J, Roschke J, Grozinger M, Hinrichs H, Heinze H: Alterations of continuous MEG measures during mental activities. Neuropsychobiology 2000, 42:99-106.
32. Hunkin NM, Mayes AR, Williams SC, Gregory LJ, Nunn JA, Nicholas AK, Brammer MJ, Bullmore ET: Does frontal lobe activation during retrieval reflect complexity of retrieved information? Neuroreport 2000, 11:557-561.
33. McEwen BS, Seeman T: Protective and damaging effects of mediators of stress. Elaborating and testing the concepts of allostasis and allostatic load. Annals of New York Academy of Sciences 1999, 896:30-47.
34. Zheng H, Liu Y, Li W, Yang B, Chen D, Wang X, Jiang Z, Wang H, Wang Z, Cornelisson G, Halberg F: Beneficial effects of exercise and its molecular mechanisms on depression in rats. Behavioural Brain Research 2006, 168(1):47-55.
35. Huang AM, Jen CJ, Chen HF, Yu L, Kuo YM, Chen HI: Compulsive exercise acutely upregulates rat hippocampal brain-derived neurotrophic factor. Journal of Neural Transmission 2006, 113(7):803-11.
36. Duman RS: Neurotrophic factors and regulation of mood: Role of exercise, diet and metabolism. Neurobiology of Aging in press. 2005 Oct 11
37. Powrozek TA, Sari Y, Singh RP, Zhou FC: Neurotransmitters and substances of abuse: effects on adult neurogenesis. Current Neurovascular Research 2004, 1:251-260.
38. Russo-Neustadt AA, Chen MJ: Brain-derived neurotrophic factor and antidepressant activity. Current Pharmaceutical Design 2005, 11:1495-1510.
39. Kleim JA, Jones TA, Schallert T: Motor enrichment and the induction of plasticity before or after brain injury. Neurochemical Research 2003, 28:1757-1769.
40. Kiraly MA, Kiraly SJ: The effect of exercise on hippocampal integrity: review of recent research. International Journal of Psychiatry in Medicine 2005, 35(1):75-89.
41. [http://www.cdc.gov/nccdphp/dnpa/physical/pdf/PA_Intensity_table_2_1.pdf] . (Accessed June 2006)
42. Freeman WJ: Brain Dynamics: Brain Chaos and Intentionality. In Integrative Neuroscience. Bringing Together Biological, Psychological and Clinical Models of the Human Brain Edited by: Gordon E. Harwood Academic Publishers, Sydney, Australia; 2000:163-171.
43. Sarbadhikari SN, Saha AK, Sreenath SN: Modeling the Role of Exercise and Stress on Depression - A System Biological Approach. In Proceedings (Abstracts) of Sixth International Conference on Systems Biology (ICSB 2005) Boston, MA. October 19-24, 2005
44. Sarbadhikari SN, Dey S, Ray AK: Chronic Exercise Alters EEG Power Spectra in an Animal Model of Depression. Indian J Physiol Pharmacol 1996, 40(1):47-57.
45. Duman RS, Monteggia LM: A Neurotrophic Model for Stress-Related Mood Disorders. Biological Psychiatry 2006, 59(12):1116-27.
46. Takeda H, Tsuji M, Yamada T, Masuya J, Matsushita K, Tahara M, Iimori M, Matsumiya T: Caffeic acid attenuates the decrease in cortical BDNF mRNA expression induced by exposure to forced swimming stress in mice. European Journal of Pharmacology 2006, 534:115-121. Epub 2006 Feb 21
47. Rogoz Z, Legutko B: Combined treatment with imipramine and metyrapone induces hippocampal and cortical brain-derived neurotrophic factor gene expression in rats. Pharmacological Reports 2005, 57:840-844.
48. De La Garza R 2nd, Mahoney JJ 3rd: A distinct neurochemical profile in WKY rats at baseline and in response to acute stress: implications for animal models of anxiety and depression. Brain Research 2004, 1021:209-218.
49. Gomez-Pinilla F, Ying Z, Roy RR, Molteni R, Edgerton VR: Voluntary exercise induces a BDNF-mediated mechanism that promotes neuroplasticity. Journal of Neurophysiology 2002, 88:2187-2195.
50. Zaldivar F, Wang-Rodriguez J, Nemet D, Schwindt C, Galassetti P, Mills PJ, Wilson LD, Cooper DM: Constitutive pro- and anti-inflammatory cytokine and growth factor response to exercise in leukocytes. Journal of Applied Physiology 2006, 100:1124-1133. Epub 2005 Dec 15
51. Bixby W, Spalding T, Hatfield B: Temporal Dynamics and Dimensional Specificity of the Affective Response to Exercise of Varying Intensity: Differing Pathways to a Common Outcome. Journal of Sport and Exercise Psychology 2001, 23:171-190.
52. Van Landuyt LM, Ekkekakis P, Hall E, Petruzzello S: Throwing the mountains into the lakes: On the perils of nomothetic conceptions of the exercise-affect relationship. Journal of Sport and Exercise Psychology 2000, 22:208-234.
53. Dishman RK, Berthoud HR, Booth FW, Cotman CW, Edgerton VR, Fleshner MR, Gandevia SC, Gomez-Pinilla F, Greenwood BN, Hillman CH, Kramer AF, Levin BE, Moran TH, Russo-Neustadt AA, Salamone JD, Van Hoomissen JD, Wade CE, York DA, Zigmond MJ: Neurobiology of exercise. Obesity (Silver Spring) 2006, 14:345-356.
54. Greenwood BN, Foley TE, Day HE, Burhans D, Brooks L, Campeau S, Fleshner M: Wheel running alters serotonin (5-HT) transporter, 5-HT1A, 5-HT1B, and alpha 1b-adrenergic receptor mRNA in the rat raphe nuclei. Biological Psychiatry 2005, 57:559-568.
55. Sarbadhikari SN: A Neural Network Confirms that Physical Exercise Reverses EEG Changes in Depressed Rats. Medical Engineering and Physics 1995, 17:579-582.
56. Sarbadhikari SN, Pal SK: Automated Techniques for identifying depression from EEG. Volume 4, Chapter 3. Edited by: Leondes CT. Handbook of Computational Methods in Biomaterials, Biotechnology & Biomedical systems, Kluwer Academic Publishers; 2002:51-81.
57. Tan U: Psychomotor Theory: Mind-Brain-Body triad in health and disease. In Depression and Dementia: Progress in Brain Research, Clinical Applications and Future Trends Volume Chp 2. Edited by: Sarbadhikari SN. Nova Biomedical, New York; 2005:21-53.
58. McMorris T, Harris RC, Swain J, Corbett J, Collard K, Dyson RJ, Dye L, Hodgson C, Draper N: Effect of creatine supplementation and sleep deprivation, with mild exercise, on cognitive and psychomotor performance, mood state, and plasma concentrations of catecholamines and cortisol. Psychopharmacology (Berl) 2006 in press.
59. Tonacio AC, Trombetta IC, Rondon MU, Batalha LT, Kuniyoshi FH, Laterza MC, Suzuki PH, Gowdak MM, Barretto AC, Halpern A, Villares SM, Negrao CE: Effects of diet and exercise training on neurovascular control during mental stress in obese women. Brazilian Journal of Medical and Biological Research 2006, 39:53-62. Epub 2005 Dec 15
60. 1A Receptor in the Antidepressant-Like Effect of Estrogens in the Forced Swimming Test. Neuropsychopharmacology 2006, 31:247-255.
61. Bjørnebekk A, Mathé AA, Brené S: Running has Differential Effects on NPY, Opiates, and Cell Proliferation in an Animal Model of Depression and Controls. Neuropsychopharmacology 2006, 31:256-264.
62. Onn S-P, Wang X-B, Lin M, Grace AA: Dopamine D1 and D4 Receptor Subtypes Differentially Modulate Recurrent Excitatory Synapses in Prefrontal Cortical Pyramidal Neurons. Neuropsychopharmacology 2006, 31:318-338.
63. Sumich AL, Kumari V, Heasman BC, Gordon E, Brammer M: Abnormal asymmetry of N200 and P300 event-related potentials in subclinical depression. Journal of Affective Disorders 2006, 92:171-183. Epub 2006 Mar 9
64. Pickard BS, Malloy MP, Christoforou A, Thomson PA, Evans KL, Morris SW, Hampson M, Porteous DJ, Blackwood DH, Muir WJ: Cytogenetic and genetic evidence supports a role for the kainate-type glutamate receptor gene, GRIK4, in schizophrenia and bipolar disorder. Molecular Psychiatry 2006, 11(9):847-57.
65. Fallin MD, Lasseter VK, Avramopoulos D, Nicodemus KK, Wolyniec PS, McGrath JA, Steel G, Nestadt G, Liang KY, Huganir RL, Valle D, Pulver AE: Bipolar I disorder and schizophrenia: a 440-single-nucleotide polymorphism screen of 64 candidate genes among Ashkenazi Jewish case-parent trios. American Journal of Human Genetics 2005, 77:918-936. Epub 2005 Oct 28
66. Etevenon P: A model of intra- and inter-hemispheric relationships. In Laterality and Psychopathology Edited by: Flor-Henry P, Gruzelier J. Elsevier, Amsterdam; 1983:291-300.
67. Koslow SH: Discovery and integrative neuroscience. Clinical EEG Neurosciences 2005, 36:55-63.
68. Procopio M: The multiple outcomes bias in antidepressants research. Medical Hypotheses 2005, 65:395-399.