메뉴 건너뛰기




Volumn 72, Issue 2, 2006, Pages 292-302

Adenosine A2A receptors are expressed in human atrial myocytes and modulate spontaneous sarcoplasmic reticulum calcium release

Author keywords

Adenosine; Arrhythmia (mechanisms); Calcium channel; e c coupling; SR (function)

Indexed keywords

2 [4 (2 CARBOXYETHYL)PHENETHYLAMINO]ADENOSINE 5' (N ETHYLCARBOXAMIDE); ADENOSINE A2 RECEPTOR; ADENOSINE A2A RECEPTOR; CALCIUM; CALCIUM CHANNEL L TYPE; CYCLIC AMP DEPENDENT PROTEIN KINASE; RECEPTOR SUBTYPE; RYANODINE RECEPTOR; VOLTAGE GATED CALCIUM CHANNEL; ADENOSINE; CAFFEINE; DRUG DERIVATIVE; ISOQUINOLINE DERIVATIVE; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; PHENETHYLAMINE DERIVATIVE; RYANODINE; SODIUM CALCIUM EXCHANGE PROTEIN; SULFONAMIDE;

EID: 33749586497     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cardiores.2006.07.020     Document Type: Article
Times cited : (58)

References (43)
  • 1
    • 0033607667 scopus 로고    scopus 로고
    • Upregulation of Na(+)/Ca(2+) exchanger expression and function in an arrhythmogenic rabbit model of heart failure
    • Pogwizd S.M., Qi M., Yuan W., Samarel A.M., and Bers D.M. Upregulation of Na(+)/Ca(2+) exchanger expression and function in an arrhythmogenic rabbit model of heart failure. Circ Res 85 (1999) 1009-1019
    • (1999) Circ Res , vol.85 , pp. 1009-1019
    • Pogwizd, S.M.1    Qi, M.2    Yuan, W.3    Samarel, A.M.4    Bers, D.M.5
  • 2
    • 0034640113 scopus 로고    scopus 로고
    • PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts
    • Marx S.O., Reiken S., Hisamatsu Y., Jayaraman T., Burkhoff D., Rosemblit N., et al. PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts. Cell 101 (2000) 365-376
    • (2000) Cell , vol.101 , pp. 365-376
    • Marx, S.O.1    Reiken, S.2    Hisamatsu, Y.3    Jayaraman, T.4    Burkhoff, D.5    Rosemblit, N.6
  • 3
    • 0037414827 scopus 로고    scopus 로고
    • Protein kinase A phosphorylation of the cardiac calcium release channel (ryanodine receptor) in normal and failing hearts. Role of phosphatases and response to isoproterenol
    • Reiken S., Gaburjakova M., Guatimosim S., Gomez A.M., D'Armiento J., Burkhoff D., et al. Protein kinase A phosphorylation of the cardiac calcium release channel (ryanodine receptor) in normal and failing hearts. Role of phosphatases and response to isoproterenol. J Biol Chem 278 (2003) 444-453
    • (2003) J Biol Chem , vol.278 , pp. 444-453
    • Reiken, S.1    Gaburjakova, M.2    Guatimosim, S.3    Gomez, A.M.4    D'Armiento, J.5    Burkhoff, D.6
  • 4
    • 0037708928 scopus 로고    scopus 로고
    • FKBP12.6 deficiency and defective calcium release channel (ryanodine receptor) function linked to exercise-induced sudden cardiac death
    • Wehrens X.H., Lehnart S.E., Huang F., Vest J.A., Reiken S.R., Mohler P.J., et al. FKBP12.6 deficiency and defective calcium release channel (ryanodine receptor) function linked to exercise-induced sudden cardiac death. Cell 113 (2003) 829-840
    • (2003) Cell , vol.113 , pp. 829-840
    • Wehrens, X.H.1    Lehnart, S.E.2    Huang, F.3    Vest, J.A.4    Reiken, S.R.5    Mohler, P.J.6
  • 5
    • 4444357245 scopus 로고    scopus 로고
    • RyR2 mutations linked to ventricular tachycardia and sudden death reduce the threshold for store-overload-induced Ca2+ release (SOICR)
    • Jiang D., Xiao B., Yang D., Wang R., Choi P., Zhang L., et al. RyR2 mutations linked to ventricular tachycardia and sudden death reduce the threshold for store-overload-induced Ca2+ release (SOICR). Proc Natl Acad Sci U S A 101 (2004) 13062-13067
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 13062-13067
    • Jiang, D.1    Xiao, B.2    Yang, D.3    Wang, R.4    Choi, P.5    Zhang, L.6
  • 6
    • 4544288714 scopus 로고    scopus 로고
    • Atrial fibrillation is associated with increased spontaneous calcium release from the sarcoplasmic reticulum in human atrial myocytes
    • Hove-Madsen L., Llach A., Bayes-Genis A., Roura S., Rodriguez Font E., Aris A., et al. Atrial fibrillation is associated with increased spontaneous calcium release from the sarcoplasmic reticulum in human atrial myocytes. Circulation 110 (2004) 1358-1363
    • (2004) Circulation , vol.110 , pp. 1358-1363
    • Hove-Madsen, L.1    Llach, A.2    Bayes-Genis, A.3    Roura, S.4    Rodriguez Font, E.5    Aris, A.6
  • 7
    • 0034721607 scopus 로고    scopus 로고
    • Sarcoplasmic reticulum Ca(2+) release causes myocyte depolarization. Underlying mechanism and threshold for triggered action potentials
    • Schlotthauer K., and Bers D.M. Sarcoplasmic reticulum Ca(2+) release causes myocyte depolarization. Underlying mechanism and threshold for triggered action potentials. Circ Res 87 (2000) 774-780
    • (2000) Circ Res , vol.87 , pp. 774-780
    • Schlotthauer, K.1    Bers, D.M.2
  • 8
    • 0038663006 scopus 로고    scopus 로고
    • Reinduction of atrial fibrillation immediately after termination of the arrhythmia is mediated by late phase 3 early afterdepolarization-induced triggered activity
    • Burashnikov A., and Antzelevitch C. Reinduction of atrial fibrillation immediately after termination of the arrhythmia is mediated by late phase 3 early afterdepolarization-induced triggered activity. Circulation 107 (2003) 2355-2360
    • (2003) Circulation , vol.107 , pp. 2355-2360
    • Burashnikov, A.1    Antzelevitch, C.2
  • 9
    • 0037047646 scopus 로고    scopus 로고
    • Enhanced basal activity of a cardiac Ca2+ release channel (ryanodine receptor) mutant associated with ventricular tachycardia and sudden death
    • Jiang D., Xiao B., Zhang L., and Chen S.R. Enhanced basal activity of a cardiac Ca2+ release channel (ryanodine receptor) mutant associated with ventricular tachycardia and sudden death. Circ Res 91 (2002) 218-225
    • (2002) Circ Res , vol.91 , pp. 218-225
    • Jiang, D.1    Xiao, B.2    Zhang, L.3    Chen, S.R.4
  • 10
    • 4444298467 scopus 로고    scopus 로고
    • Sudden death in familial polymorphic ventricular tachycardia associated with calcium release channel (ryanodine receptor) leak
    • Lehnart S.E., Wehrens X.H., Laitinen P.J., Reiken S.R., Deng S.X., Cheng Z., et al. Sudden death in familial polymorphic ventricular tachycardia associated with calcium release channel (ryanodine receptor) leak. Circulation 109 (2004) 3208-3214
    • (2004) Circulation , vol.109 , pp. 3208-3214
    • Lehnart, S.E.1    Wehrens, X.H.2    Laitinen, P.J.3    Reiken, S.R.4    Deng, S.X.5    Cheng, Z.6
  • 11
    • 0037131020 scopus 로고    scopus 로고
    • Absence of calsequestrin 2 causes severe forms of catecholaminergic polymorphic ventricular tachycardia
    • Postma A.V., Denjoy I., Hoorntje T.M., Lupoglazoff J.M., Da Costa A., Sebillon P., et al. Absence of calsequestrin 2 causes severe forms of catecholaminergic polymorphic ventricular tachycardia. Circ Res 91 (2002) e21-e26
    • (2002) Circ Res , vol.91
    • Postma, A.V.1    Denjoy, I.2    Hoorntje, T.M.3    Lupoglazoff, J.M.4    Da Costa, A.5    Sebillon, P.6
  • 12
    • 0036645605 scopus 로고    scopus 로고
    • Clinical and molecular characterization of patients with catecholaminergic polymorphic ventricular tachycardia
    • Priori S.G., Napolitano C., Memmi M., Colombi B., Drago F., Gasparini M., et al. Clinical and molecular characterization of patients with catecholaminergic polymorphic ventricular tachycardia. Circulation 106 (2002) 69-74
    • (2002) Circulation , vol.106 , pp. 69-74
    • Priori, S.G.1    Napolitano, C.2    Memmi, M.3    Colombi, B.4    Drago, F.5    Gasparini, M.6
  • 13
    • 0035969990 scopus 로고    scopus 로고
    • Mutations of the cardiac ryanodine receptor (RyR2) gene in familial polymorphic ventricular tachycardia
    • Laitinen P.J., Brown K.M., Piippo K., Swan H., Devaney J.M., Brahmbhatt B., et al. Mutations of the cardiac ryanodine receptor (RyR2) gene in familial polymorphic ventricular tachycardia. Circulation 103 (2001) 485-490
    • (2001) Circulation , vol.103 , pp. 485-490
    • Laitinen, P.J.1    Brown, K.M.2    Piippo, K.3    Swan, H.4    Devaney, J.M.5    Brahmbhatt, B.6
  • 15
    • 0038662725 scopus 로고    scopus 로고
    • Beta-blockers restore calcium release channel function and improve cardiac muscle performance in human heart failure
    • Reiken S., Wehrens X.H., Vest J.A., Barbone A., Klotz S., Mancini D., et al. Beta-blockers restore calcium release channel function and improve cardiac muscle performance in human heart failure. Circulation 107 (2003) 2459-2466
    • (2003) Circulation , vol.107 , pp. 2459-2466
    • Reiken, S.1    Wehrens, X.H.2    Vest, J.A.3    Barbone, A.4    Klotz, S.5    Mancini, D.6
  • 16
    • 0030612311 scopus 로고    scopus 로고
    • Adenosine A2 receptor function in rat ventricular myocytes
    • Dobson Jr. J.G., and Fenton R.A. Adenosine A2 receptor function in rat ventricular myocytes. Cardiovasc Res 34 (1997) 337-347
    • (1997) Cardiovasc Res , vol.34 , pp. 337-347
    • Dobson Jr., J.G.1    Fenton, R.A.2
  • 18
    • 33745341849 scopus 로고    scopus 로고
    • Characterization of a stimulatory adenosine A2a receptor in adult rat ventricular myocyte
    • Xu H., Stein B., and Liang B. Characterization of a stimulatory adenosine A2a receptor in adult rat ventricular myocyte. Am J Physiol 270 (1996) H1655-H1661
    • (1996) Am J Physiol , vol.270
    • Xu, H.1    Stein, B.2    Liang, B.3
  • 19
    • 0031406523 scopus 로고    scopus 로고
    • Characterization of biochemical effects of CGS 21680C, an A2-adenosine receptor agonist, in the mammalian ventricle
    • Boknik P., Neumann J., Schmitz W., Scholz H., and Wenzlaff H. Characterization of biochemical effects of CGS 21680C, an A2-adenosine receptor agonist, in the mammalian ventricle. J Cardiovasc Pharmacol 30 (1997) 750-758
    • (1997) J Cardiovasc Pharmacol , vol.30 , pp. 750-758
    • Boknik, P.1    Neumann, J.2    Schmitz, W.3    Scholz, H.4    Wenzlaff, H.5
  • 20
    • 0036081636 scopus 로고    scopus 로고
    • Cardiac myocyte adenosine A2a receptor activation fails to alter cAMP or contractility: role of receptor localization
    • Kilpatrick E.L., Narayan P., Mentzer Jr. R.M., and Lasley R.D. Cardiac myocyte adenosine A2a receptor activation fails to alter cAMP or contractility: role of receptor localization. Am J Physiol Heart Circ Physiol 282 (2002) H1035-H1040
    • (2002) Am J Physiol Heart Circ Physiol , vol.282
    • Kilpatrick, E.L.1    Narayan, P.2    Mentzer Jr., R.M.3    Lasley, R.D.4
  • 21
    • 0034978548 scopus 로고    scopus 로고
    • Functional and molecular characterization of receptor subtypes mediating coronary microvascular dilation to adenosine
    • Hein T.W., Wang W., Zoghi B., Muthuchamy M., and Kuo L. Functional and molecular characterization of receptor subtypes mediating coronary microvascular dilation to adenosine. J Mol Cell Cardiol 33 (2001) 271-282
    • (2001) J Mol Cell Cardiol , vol.33 , pp. 271-282
    • Hein, T.W.1    Wang, W.2    Zoghi, B.3    Muthuchamy, M.4    Kuo, L.5
  • 22
    • 0036153903 scopus 로고    scopus 로고
    • Human A(2A) adenosine receptors: high-affinity agonist binding to receptor-G protein complexes containing Gbeta(4)
    • Murphree L.J., Marshall M.A., Rieger J.M., MacDonald T.L., and Linden J. Human A(2A) adenosine receptors: high-affinity agonist binding to receptor-G protein complexes containing Gbeta(4). Mol Pharmacol 61 (2002) 455-462
    • (2002) Mol Pharmacol , vol.61 , pp. 455-462
    • Murphree, L.J.1    Marshall, M.A.2    Rieger, J.M.3    MacDonald, T.L.4    Linden, J.5
  • 23
    • 0033128549 scopus 로고    scopus 로고
    • Adenosine A2a-receptor activation enhances cardiomyocyte shortening via Ca2+-independent and -dependent mechanisms
    • Woodiwiss A.J., Honeyman T.W., Fenton R.A., and Dobson Jr. J.G. Adenosine A2a-receptor activation enhances cardiomyocyte shortening via Ca2+-independent and -dependent mechanisms. Am J Physiol 276 (1999) H1434-H1441
    • (1999) Am J Physiol , vol.276
    • Woodiwiss, A.J.1    Honeyman, T.W.2    Fenton, R.A.3    Dobson Jr., J.G.4
  • 25
    • 17944383882 scopus 로고    scopus 로고
    • The adenosine A2A receptor interacts with the actin-binding protein alpha-actinin
    • Burgueno J., Blake D.J., Benson M.A., Tinsley C.L., Esapa C.T., Canela E.I., et al. The adenosine A2A receptor interacts with the actin-binding protein alpha-actinin. J Biol Chem 278 (2003) 37545-37552
    • (2003) J Biol Chem , vol.278 , pp. 37545-37552
    • Burgueno, J.1    Blake, D.J.2    Benson, M.A.3    Tinsley, C.L.4    Esapa, C.T.5    Canela, E.I.6
  • 26
    • 0028985363 scopus 로고
    • Functional coupling of Ca2+ channels and ryanodine receptors in cardiac myocytes
    • Sham J.S., Cleemann L., and Morad M. Functional coupling of Ca2+ channels and ryanodine receptors in cardiac myocytes. Proc Natl Acad Sci U S A 92 (1995) 121-125
    • (1995) Proc Natl Acad Sci U S A , vol.92 , pp. 121-125
    • Sham, J.S.1    Cleemann, L.2    Morad, M.3
  • 27
    • 0031067799 scopus 로고    scopus 로고
    • Effects of [Ca2+]i, SR Ca2+ load, and rest on Ca2+ spark frequency in ventricular myocytes
    • Satoh H., Blatter L.A., and Bers D.M. Effects of [Ca2+]i, SR Ca2+ load, and rest on Ca2+ spark frequency in ventricular myocytes. Am J Physiol 272 (1997) H657-H668
    • (1997) Am J Physiol , vol.272
    • Satoh, H.1    Blatter, L.A.2    Bers, D.M.3
  • 28
    • 0029005888 scopus 로고
    • The control of calcium release in heart muscle
    • Cannell M.B., Cheng H., and Lederer W.J. The control of calcium release in heart muscle. Science 268 (1995) 1045-1049
    • (1995) Science , vol.268 , pp. 1045-1049
    • Cannell, M.B.1    Cheng, H.2    Lederer, W.J.3
  • 29
    • 0030766026 scopus 로고    scopus 로고
    • Calcium sparks and excitation-contraction coupling in phospholamban-deficient mouse ventricular myocytes
    • Santana L.F., Kranias E.G., and Lederer W.J. Calcium sparks and excitation-contraction coupling in phospholamban-deficient mouse ventricular myocytes. J Physiol 503 Pt 1 (1997) 21-29
    • (1997) J Physiol , vol.503 , Issue.PART 1 , pp. 21-29
    • Santana, L.F.1    Kranias, E.G.2    Lederer, W.J.3
  • 30
    • 0034902242 scopus 로고    scopus 로고
    • Dynamic regulation of sarcoplasmic reticulum Ca(2+) content and release by luminal Ca(2+)-sensitive leak in rat ventricular myocytes
    • Lukyanenko V., Viatchenko-Karpinski S., Smirnov A., Wiesner T.F., and Gyorke S. Dynamic regulation of sarcoplasmic reticulum Ca(2+) content and release by luminal Ca(2+)-sensitive leak in rat ventricular myocytes. Biophys J 81 (2001) 785-798
    • (2001) Biophys J , vol.81 , pp. 785-798
    • Lukyanenko, V.1    Viatchenko-Karpinski, S.2    Smirnov, A.3    Wiesner, T.F.4    Gyorke, S.5
  • 31
    • 0027426069 scopus 로고
    • Calcium sparks: elementary events underlying excitation-contraction coupling in heart muscle
    • Cheng H., Lederer W.J., and Cannell M.B. Calcium sparks: elementary events underlying excitation-contraction coupling in heart muscle. Science 262 (1993) 740-744
    • (1993) Science , vol.262 , pp. 740-744
    • Cheng, H.1    Lederer, W.J.2    Cannell, M.B.3
  • 32
    • 0027500251 scopus 로고
    • Inositol 1,4,5-trisphosphate receptor expression in cardiac myocytes
    • Moschella M.C., and Marks A.R. Inositol 1,4,5-trisphosphate receptor expression in cardiac myocytes. J Cell Biol 120 (1993) 1137-1146
    • (1993) J Cell Biol , vol.120 , pp. 1137-1146
    • Moschella, M.C.1    Marks, A.R.2
  • 33
    • 0036623944 scopus 로고    scopus 로고
    • The role of inositol 1,4,5-trisphosphate receptors in Ca(2+) signalling and the generation of arrhythmias in rat atrial myocytes
    • Mackenzie L., Bootman M.D., Laine M., Berridge M.J., Thuring J., Holmes A., et al. The role of inositol 1,4,5-trisphosphate receptors in Ca(2+) signalling and the generation of arrhythmias in rat atrial myocytes. J Physiol 541 (2002) 395-409
    • (2002) J Physiol , vol.541 , pp. 395-409
    • Mackenzie, L.1    Bootman, M.D.2    Laine, M.3    Berridge, M.J.4    Thuring, J.5    Holmes, A.6
  • 34
    • 0034720882 scopus 로고    scopus 로고
    • Functional InsP3 receptors that may modulate excitation-contraction coupling in the heart
    • Lipp P., Laine M., Tovey S.C., Burrell K.M., Berridge M.J., Li W., et al. Functional InsP3 receptors that may modulate excitation-contraction coupling in the heart. Curr Biol 10 (2000) 939-942
    • (2000) Curr Biol , vol.10 , pp. 939-942
    • Lipp, P.1    Laine, M.2    Tovey, S.C.3    Burrell, K.M.4    Berridge, M.J.5    Li, W.6
  • 35
    • 1642524970 scopus 로고    scopus 로고
    • Inositol-1,4,5-trisphosphate-dependent Ca(2+) signalling in cat atrial excitation-contraction coupling and arrhythmias
    • Zima A.V., and Blatter L.A. Inositol-1,4,5-trisphosphate-dependent Ca(2+) signalling in cat atrial excitation-contraction coupling and arrhythmias. J Physiol 555 (2004) 607-615
    • (2004) J Physiol , vol.555 , pp. 607-615
    • Zima, A.V.1    Blatter, L.A.2
  • 36
    • 0036665629 scopus 로고    scopus 로고
    • Effects of adenosine analogs on inositol 1,4,5-trisphosphate production in porcine coronary artery
    • Abebe W., and Mustafa S.J. Effects of adenosine analogs on inositol 1,4,5-trisphosphate production in porcine coronary artery. Vascul Pharmacol 39 (2002) 89-95
    • (2002) Vascul Pharmacol , vol.39 , pp. 89-95
    • Abebe, W.1    Mustafa, S.J.2
  • 37
    • 0034721781 scopus 로고    scopus 로고
    • Targeted phosphorylation of inositol 1,4,5-trisphosphate receptors selectively inhibits localized Ca2+ release and shapes oscillatory Ca2+ signals
    • Giovannucci D.R., Groblewski G.E., Sneyd J., and Yule D.I. Targeted phosphorylation of inositol 1,4,5-trisphosphate receptors selectively inhibits localized Ca2+ release and shapes oscillatory Ca2+ signals. J Biol Chem 275 (2000) 33704-33711
    • (2000) J Biol Chem , vol.275 , pp. 33704-33711
    • Giovannucci, D.R.1    Groblewski, G.E.2    Sneyd, J.3    Yule, D.I.4
  • 38
    • 0007191908 scopus 로고    scopus 로고
    • Phosphorylation of inositol 1,4,5-trisphosphate receptors by cAMP-dependent protein kinase. Type I, II, and III receptors are differentially susceptible to phosphorylation and are phosphorylated in intact cells
    • Wojcikiewicz R.J., and Luo S.G. Phosphorylation of inositol 1,4,5-trisphosphate receptors by cAMP-dependent protein kinase. Type I, II, and III receptors are differentially susceptible to phosphorylation and are phosphorylated in intact cells. J Biol Chem 273 (1998) 5670-5677
    • (1998) J Biol Chem , vol.273 , pp. 5670-5677
    • Wojcikiewicz, R.J.1    Luo, S.G.2
  • 39
    • 0345803003 scopus 로고    scopus 로고
    • Characterization of recombinant skeletal muscle (Ser-2843) and cardiac muscle (Ser-2809) ryanodine receptor phosphorylation mutants
    • Stange M., Xu L., Balshaw D., Yamaguchi N., and Meissner G. Characterization of recombinant skeletal muscle (Ser-2843) and cardiac muscle (Ser-2809) ryanodine receptor phosphorylation mutants. J Biol Chem 278 (2003) 51693-51702
    • (2003) J Biol Chem , vol.278 , pp. 51693-51702
    • Stange, M.1    Xu, L.2    Balshaw, D.3    Yamaguchi, N.4    Meissner, G.5
  • 40
    • 20944432898 scopus 로고    scopus 로고
    • Characterization of a novel PKA phosphorylation site, serine-2030, reveals no PKA hyperphosphorylation of the cardiac ryanodine receptor in canine heart failure
    • Xiao B., Jiang M.T., Zhao M., Yang D., Sutherland C., Lai F.A., et al. Characterization of a novel PKA phosphorylation site, serine-2030, reveals no PKA hyperphosphorylation of the cardiac ryanodine receptor in canine heart failure. Circ Res 96 (2005) 847-855
    • (2005) Circ Res , vol.96 , pp. 847-855
    • Xiao, B.1    Jiang, M.T.2    Zhao, M.3    Yang, D.4    Sutherland, C.5    Lai, F.A.6
  • 41
    • 2642705036 scopus 로고    scopus 로고
    • A novel lipid-anchored A-kinase Anchoring Protein facilitates cAMP-responsive membrane events
    • Fraser I.D., Tavalin S.J., Lester L.B., Langeberg L.K., Westphal A.M., Dean R.A., et al. A novel lipid-anchored A-kinase Anchoring Protein facilitates cAMP-responsive membrane events. EMBO J 17 (1998) 2261-2272
    • (1998) EMBO J , vol.17 , pp. 2261-2272
    • Fraser, I.D.1    Tavalin, S.J.2    Lester, L.B.3    Langeberg, L.K.4    Westphal, A.M.5    Dean, R.A.6
  • 42
    • 0030025596 scopus 로고    scopus 로고
    • cAMP compartmentation is responsible for a local activation of cardiac Ca2+ channels by beta-adrenergic agonists
    • Jurevicius J., and Fischmeister R. cAMP compartmentation is responsible for a local activation of cardiac Ca2+ channels by beta-adrenergic agonists. Proc Natl Acad Sci U S A 93 (1996) 295-299
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 295-299
    • Jurevicius, J.1    Fischmeister, R.2
  • 43
    • 0036500494 scopus 로고    scopus 로고
    • Discrete microdomains with high concentration of cAMP in stimulated rat neonatal cardiac myocytes
    • Zaccolo M., and Pozzan T. Discrete microdomains with high concentration of cAMP in stimulated rat neonatal cardiac myocytes. Science 295 (2002) 1711-1715
    • (2002) Science , vol.295 , pp. 1711-1715
    • Zaccolo, M.1    Pozzan, T.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.