-
1
-
-
30944446883
-
Lessons from phase III clinical trials on anti-VEGF therapy for cancer
-
Jain RK, Duda DG, Clark JW et al. Lessons from phase III clinical trials on anti-VEGF therapy for cancer. Nat Clin Pract Oncol 2006; 3: 24-40.
-
(2006)
Nat Clin Pract Oncol
, vol.3
, pp. 24-40
-
-
Jain, R.K.1
Duda, D.G.2
Clark, J.W.3
-
2
-
-
30744449235
-
Angiogenesis as a therapeutic target
-
Ferrara N, Kerbel RS. Angiogenesis as a therapeutic target. Nature 2005; 438: 967-974.
-
(2005)
Nature
, vol.438
, pp. 967-974
-
-
Ferrara, N.1
Kerbel, R.S.2
-
3
-
-
4143136640
-
Vascular endothelial growth factor: Basic science and clinical progress
-
Ferrara N. Vascular endothelial growth factor: Basic science and clinical progress. Endocr Rev 2004; 25; 581-611.
-
(2004)
Endocr Rev
, vol.25
, pp. 581-611
-
-
Ferrara, N.1
-
4
-
-
0030031898
-
Expression of vascular permeability factor/vascular endothelial growth factor by melanoma cells increases tumor growth, angiogenesis, and experimental metastasis
-
Claffey KP, Brown LF, del Aguila LF et al. Expression of vascular permeability factor/vascular endothelial growth factor by melanoma cells increases tumor growth, angiogenesis, and experimental metastasis. Cancer Res 1996; 56: 172-181.
-
(1996)
Cancer Res
, vol.56
, pp. 172-181
-
-
Claffey, K.P.1
Brown, L.F.2
del Aguila, L.F.3
-
5
-
-
0034129125
-
The 121 amino acid isoform of vascular enoothelial growth factor is more strongly tumorigenic than other splice variants in vivo
-
Zhang HT, Scott PA, Morbidelli L et al. The 121 amino acid isoform of vascular enoothelial growth factor is more strongly tumorigenic than other splice variants in vivo. Br J Cancer 2000; 83: 63-68.
-
(2000)
Br J Cancer
, vol.83
, pp. 63-68
-
-
Zhang, H.T.1
Scott, P.A.2
Morbidelli, L.3
-
6
-
-
0027197245
-
Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo
-
Kim KJ, Li B, Winer J et al. Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo. Nature 1993; 362: 841-444.
-
(1993)
Nature
, vol.362
, pp. 444-841
-
-
Kim, K.J.1
Li, B.2
Winer, J.3
-
7
-
-
2442621619
-
Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer
-
Ferrara N, Hillan KJ, Gerber HP et al. Discovery and development of bevacizumab, an anti-VEGF antibody for treating cancer. Nat Rev Drug Discov 2004; 3: 391-400.
-
(2004)
Nat Rev Drug Discov
, vol.3
, pp. 391-400
-
-
Ferrara, N.1
Hillan, K.J.2
Gerber, H.P.3
-
8
-
-
2542561964
-
Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
-
Hurwitz H, Fehrenbacher L, Novotny W et al. Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med 2004; 350: 2335-2342.
-
(2004)
N Engl J Med
, vol.350
, pp. 2335-2342
-
-
Hurwitz, H.1
Fehrenbacher, L.2
Novotny, W.3
-
9
-
-
33749603413
-
Bevacizumab (Avastin) for the treatment of solid tumors: NCI fact Sheet
-
Bevacizumab (Avastin) for the treatment of solid tumors: NCI fact Sheet [http://cancer.gov/cancertopicsfactsheet/AvastinFactSheet].
-
-
-
-
10
-
-
22244452376
-
VEGF-targeted therapy: Therapeutic potential and recent advances
-
Rosen LS. VEGF-targeted therapy: Therapeutic potential and recent advances. Oncologist 2005; 10 (6): 382-391.
-
(2005)
Oncologist
, vol.10
, Issue.6
, pp. 382-391
-
-
Rosen, L.S.1
-
11
-
-
30944455338
-
Clinical trials comparing carboplatin/paclitaxel with and without bevacizumab in patients with metastatic NSCLC
-
Sandler AB, Clinical trials comparing carboplatin/paclitaxel with and without bevacizumab in patients with metastatic NSCLC. Lung Cancer Update 2005; 2: 6-10.
-
(2005)
Lung Cancer Update
, vol.2
, pp. 6-10
-
-
Sandler, A.B.1
-
12
-
-
33644837728
-
Overstated conclusions of a pooled analysis of bevacizumab in colon cancer
-
528-529 author reply
-
Goffin JR, Talavera JR. Overstated conclusions of a pooled analysis of bevacizumab in colon cancer. J Clin Oncol 2006; 24: 528-529; author reply 529-530.
-
(2006)
J Clin Oncol
, vol.24
, pp. 529-530
-
-
Goffin, J.R.1
Talavera, J.R.2
-
13
-
-
20044364346
-
Randomized phase III trial of capecitabine compared with bevacizumab plus capecitabine in patients with previously treated metastatic breast cancer
-
Miller KD, Chap LI, Holmes FA et al. Randomized phase III trial of capecitabine compared with bevacizumab plus capecitabine in patients with previously treated metastatic breast cancer. J Clin Oncol 2005; 23: 792-799.
-
(2005)
J Clin Oncol
, vol.23
, pp. 792-799
-
-
Miller, K.D.1
Chap, L.I.2
Holmes, F.A.3
-
14
-
-
1942486848
-
Recognition of tumor blood vessel normalization as a new antiangiogenic concept
-
329; author reply
-
Hellmann K. Recognition of tumor blood vessel normalization as a new antiangiogenic concept. Nat Med 2004; 10: 329; author reply 329-30.
-
(2004)
Nat Med
, vol.10
, pp. 329-330
-
-
Hellmann, K.1
-
15
-
-
0035906856
-
3D microvascular architecture of precancerous lesions and invasive carcinomas of the colon
-
Konerding MA, Fait E, Gaumann A. 3D microvascular architecture of precancerous lesions and invasive carcinomas of the colon. Br J Cancer 2001; 84: 1354-1362.
-
(2001)
Br J Cancer
, vol.84
, pp. 1354-1362
-
-
Konerding, M.A.1
Fait, E.2
Gaumann, A.3
-
16
-
-
0038376001
-
Imaging of angiogenesis: From microscope to clinic
-
McDonald DM, Choyke PL. Imaging of angiogenesis: From microscope to clinic. Nat Med 2003; 9: 713-725.
-
(2003)
Nat Med
, vol.9
, pp. 713-725
-
-
McDonald, D.M.1
Choyke, P.L.2
-
17
-
-
0034796595
-
Normalizing tumor vasculature with anti-angiogenic therapy: A new paradigm for combination therapy
-
Jain RK. Normalizing tumor vasculature with anti-angiogenic therapy: A new paradigm for combination therapy. Nat Med 2001; 7: 987-989.
-
(2001)
Nat Med
, vol.7
, pp. 987-989
-
-
Jain, R.K.1
-
18
-
-
0035869407
-
Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2
-
Slamon DJ, Leyland-Jones B, Shak S et al. Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2. N Engl J Med 2001; 344: 783-792.
-
(2001)
N Engl J Med
, vol.344
, pp. 783-792
-
-
Slamon, D.J.1
Leyland-Jones, B.2
Shak, S.3
-
19
-
-
26844503270
-
Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer
-
Piccart-Gebhart MJ, Procter M, Leyland-Jones B et al. Trastuzumab after adjuvant chemotherapy in HER2-positive breast cancer. N Engl J Med 2005; 353: 1659-1672.
-
(2005)
N Engl J Med
, vol.353
, pp. 1659-1672
-
-
Piccart-Gebhart, M.J.1
Procter, M.2
Leyland-Jones, B.3
-
20
-
-
26844536978
-
Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer
-
Romond EH, Perez EA, Bryant J et al. Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer. N Engl J Med 2005; 353: 1673-1684.
-
(2005)
N Engl J Med
, vol.353
, pp. 1673-1684
-
-
Romond, E.H.1
Perez, E.A.2
Bryant, J.3
-
21
-
-
0037149539
-
Tumour biology: Herceptin acts as an anti-angiogenic cocktail
-
Izumi Y, Xu L, di Tomaso E et al. Tumour biology: Herceptin acts as an anti-angiogenic cocktail. Nature 2002; 416 (6878): 279-280.
-
(2002)
Nature
, vol.416
, Issue.6878
, pp. 279-280
-
-
Izumi, Y.1
Xu, L.2
di Tomaso, E.3
-
22
-
-
0028670833
-
Integrin alpha v beta 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels
-
Brooks PC, Montgomery AM, Rosenfeld M et al. Integrin alpha v beta 3 antagonists promote tumor regression by inducing apoptosis of angiogenic blood vessels. Cell 1994; 79: 1157-1164.
-
(1994)
Cell
, vol.79
, pp. 1157-1164
-
-
Brooks, P.C.1
Montgomery, A.M.2
Rosenfeld, M.3
-
23
-
-
0031038068
-
Expression of the angiogenic factors vascular endothelial cell growth factor, acidic and basic fibroblast growth factor, tumor growth factor beta-1, platelet-derived endothelial cell growth factor, placenta growth factor, and pleiotrophin in human primary breast cancer and its relation to angiogenesis
-
Relf M, LeJeune S, Scott PA et al. Expression of the angiogenic factors vascular endothelial cell growth factor, acidic and basic fibroblast growth factor, tumor growth factor beta-1, platelet-derived endothelial cell growth factor, placenta growth factor, and pleiotrophin in human primary breast cancer and its relation to angiogenesis. Cancer Res 1997; 57: 963-969.
-
(1997)
Cancer Res
, vol.57
, pp. 963-969
-
-
Relf, M.1
LeJeune, S.2
Scott, P.A.3
-
24
-
-
14644393663
-
Thymidine phosphorylase (platelet-derived endothelial-cell growth factor) in cancer biology and treatment
-
Toi M, Atiqur Rahman M, Bando H et al. Thymidine phosphorylase (platelet-derived endothelial-cell growth factor) in cancer biology and treatment. Lancet Oncol 2005; 6: 158-166.
-
(2005)
Lancet Oncol
, vol.6
, pp. 158-166
-
-
Toi, M.1
Atiqur Rahman, M.2
Bando, H.3
-
26
-
-
20344367537
-
Tumour vascular targeting
-
Neri D, Bicknell R. Tumour vascular targeting. Nat Rev Cancer 2005; 5 (6): 436-446.
-
(2005)
Nat Rev Cancer
, vol.5
, Issue.6
, pp. 436-446
-
-
Neri, D.1
Bicknell, R.2
-
27
-
-
0027368441
-
Eradication of large solid tumors in mice with an immunotoxin directed against tumor vasculature
-
Burrows FJ, Thorpe PE. Eradication of large solid tumors in mice with an immunotoxin directed against tumor vasculature. Proc Natl Acad Sci USA 1993; 90: 8996-9000.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 8996-9000
-
-
Burrows, F.J.1
Thorpe, P.E.2
|