Catalytic mechanism of S-ribosylhomocysteinase: Ionization state of active-site residues

Biochemistry

Volumn 45, Issue 40, 2006, Pages 12195-12203

  Zhu, Jinge ^a   Knottenbelt, Sushilla ^b   Kirk, Martin L ^b   Pei, Dehua ^a  

^a OHIO STATE UNIVERSITY   (United States)

^b UNIVERSITY OF NEW MEXICO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LEWIS ACID; S-RIBOSYLHOMOCYSTEINASE; THIOLATE ANIONS;

CATALYSIS; ETHERS; IONIZATION; PARAMAGNETIC RESONANCE; REACTION KINETICS; REDOX REACTIONS;

ENZYMES;

4,5 DIHYDROXY 2,3 PENTANEDIONE; ACETYLACETONE; ACID; ARGININE; BASE; CARBONYL DERIVATIVE; COBALT; CYSTEINE; FERROUS ION; LEWIS ACID; METAL ION; RIBOSE; S RIBOSYLHOMOCYSTEINASE; SULFIDE; THIOL DERIVATIVE; UNCLASSIFIED DRUG; WATER; ZINC ION;

ABSORPTION SPECTROSCOPY; ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; ELECTRON SPIN RESONANCE; ELIMINATION REACTION; ENZYME ACTIVE SITE; ENZYME MECHANISM; ESCHERICHIA COLI; IONIZATION; MOLECULAR STABILITY; NONHUMAN; OXIDATION REDUCTION REACTION; PH; PKA; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; WILD TYPE;

AMINO ACID SEQUENCE; ARGININE; BACTERIAL PROTEINS; BINDING SITES; CARBON-SULFUR LYASES; CHLORIDES; CYSTEINE; ELECTRON SPIN RESONANCE SPECTROSCOPY; HYDROGEN-ION CONCENTRATION; IONS; MUTAGENESIS, SITE-DIRECTED; QUANTUM THEORY; SPECTROPHOTOMETRY, ULTRAVIOLET;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 33749512434     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi061434v     Document Type: Article

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