The progression of bone and muscle atrophy in mice hind limb with immobilization

Hiroshima Journal of Medical Sciences

Volumn 55, Issue 3, 2006, Pages 79-83

  Minematsu, Akira ^a   Imagita, Hidetaka ^a   Kanemura, Naohiko ^b   Yoshimura, Osamu ^c  

^a KIO UNIVERSITY   (Japan)

^b HIROSHIMA UNIVERSITY   (Japan)

^c Hiroshima City Rehabilitation Agency for Physically Handicapped Persons   (Japan)

Author keywords

Bone and muscle atrophy; Bone mechanical strength; Immobilization; Muscle cross sectional area

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE ATROPHY; BONE STRENGTH; CONTROLLED STUDY; DENERVATION; FRACTURE FIXATION; IMMOBILIZATION; MALE; MOUSE; MUSCLE ATROPHY; NONHUMAN; PLASTER CAST; RECTUS FEMORIS MUSCLE; SCIATIC NERVE;

ANIMALS; ATROPHY; BIOMECHANICS; BONE AND BONES; HINDLIMB SUSPENSION; MALE; MICE; MICE, INBRED C57BL; MUSCULAR ATROPHY;

EID: 33749488913     PISSN: 00182052     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. Belanger, M., Stein, R.B., Wheeler, G.D., Gordon, T. and Leduc, B. 2000. Electrical stimulation: can it increase muscle strength and reverse osteopenia in spinal cord injured individual? Arch. Phys. Med. Rehabil. 81: 1090-1098.
2. Bemben, D.A. and Langdon, D.B. 2002. Relationship between estrogen use and musculoskeletal function in postmenopausal women. Maturitas 42: 119-127.
3. Bloomfield, S.A. 1997. Changes in musculoskeletal structure and function with prolonged bed rest. Med. Sci. Sports. Exerc. 29: 197-206.
4. Booth, F.W. 1997. Time course of muscular atrophy during immobilization of hindlimbs in rats. J. Appl. Physiol. 43: 656-661.
5. Booth, F.W. and Gollnick, P.D. 1983. Effects of disuse on the structure and function of skeletal muscle. Med. Sci. Sports. Exerc. 15: 415-420.
6. Booth, F.W. 1987. Physiologic and biochemical effects of immobilization on muscle. Clin. Orthop. Relat. Res. 219:15-20.
7. Booth, F.W. 1994. Terrestrial applications of bone and muscle research in microgravity. Adv. Space. Res. 14: 373-376.
8. Brown, M., Fishe, J.S. and Hasser, E.M. 2001. Gonadectomy and reduced physical activity: Effects on skeletal muscle. Arch. Phys. Med. Rehabil. 82: 93-97.
9. Brown, M. and Hasser, E.M. 1995. Weight-bearing effects on skeletal muscle during and after stimulated bed rest. Arch. Phys. Med. Rehabil. 76: 541-546.
10. Dedkov, E.I., Borisov, A.B. and Carlson, B.M. 2003. Dynamics of postdenervation atrophy of young and old skeletal muscles: differential responses of fiber types and muscle types. J. Gerontol. A Biol. Sci. 58: 984-991.
11. Desplanches, D. 1997. Structure and functional adaptations of skeletal muscle to weightlessness. Int. J. Sports Med. 18 (Suppl 4): S259-264.
12. Fitts, R.H., Riley, D.R. and Widrick, J.J. 2001. Functional and structural adaptations of skeletal muscle to microgravity. J. Exp. Biol. 204: 3201-3208.
13. Hachisuka, K., Umezu, U. and Ogata, H. 1997. Disuse muscle atrophy of lower limbs in hemiplegic patients. Arch. Phys. Med. Rehabil. 78: 13-18.
14. Humphries, B., Triplett-McBride, T., Newton, R.U., Marshall, S., Bronks, R., McBride, J., Hakkinen, K. and Kraemer, W.J. 1999. The relationship between dynamic, isokinetic and isometric strength and bone mineral density in a population of 45 to 65 year old women. J. Sci. Med. Sport 2: 364-374.
15. Kasper, C.E., McNulty, A.L., Otto, A.J. and Thompson, D.P. 1993. Alterations in skeletal muscle related to impaired physical mobility: an empirical model. Res. Nurs. Health 16: 265-273.
16. Kawakami, Y., Muraoka, Y., Kubo, K., Suzuki, Y. and Fukunaga, T. 2000. Changes in muscle size and architecture following 20 days of bed rest. J. Gravit. Physiol. 7: 53-59.
17. Kodama, Y., Dimai, H.P., Wergedal, J., Sheng, M., Maple, R., Kutilek, S., Beamer, W., Donahue, L.R., Rosen, C., Baylink, D.J. and Farley, J. 1999. Cortical tibial bone volume in two strains of mice: effects of sciatic neurectomy and genetic regulation of bone response to mechanical loading. Bone 25:183-190.
18. Lee, Y.H., Rah, J.H., Park, R.W. and Park, C.I. 2001. The effect of early therapeutic electrical stimulation on bone mineral density in the paralyzed limbs of the rabbit. Yonsei Med. J. 42:194-198.
19. Miller, L.E., Nickols-Richardson, S.M., Wootten, D.F., Ramp, W.K. and Herbert, W.G. 2004. Relationships among bone mineral density, body composition, and isokinetic strength in young women. Calcif. Tissue Int. 74: 229-235.
20. Minaire, P., Neunier, P., Edouard, C., Bernard, J., Courpron, P. and Bourret, J. 1974. Quantitative histological data on disuse osteoporosis: comparison with biological data. Calcif. Tissue Int. 17: 57-73.
21. Minematsu, A., Yoshimura, O., Maejima, H. and Miyamoto, T. 2003. Change of bone mechanical strength in rats after spinal cord injury over a short term. Hiroshima J. Med. Sci. 52: 21-25.
22. Musacchia, X.J., Steffen, J.M., Fell, R.D. and Dombrowski, M.J. 1988. Comparative morphometry of fibers and capillaries in soleus following weightlessness (SL-3) and suspension. Physiologist 31 (Suppl 1): S28-29.
23. Nicks, D.K., Beneke, W.M., Key, R.M. and Timson, B.F. 1989. Muscle fiber size and number following immobilization atrophy. J. Anat. 163: 1-5.
24. Nodim, J.O. 1999. Quantitative study of the effects of denervation and castration on the levator ani muscle of the rat. Anat. Rec. 255: 324-333.
25. Pettersson, U., Alfredson, H., Nordstorm, P., Henriksson-Larsen, K. and Lorentzon, R. 2000. Bone mass in female cross-country skiers: relationship between muscle strength and different BMD sites. Calcif. Tissue Int. 67:199-206.
26. Qin, L., Appell, H.J., Chan, K.M. and Maffulli, N. 1997. Electrical stimulation prevents immobilization atrophy in skeletal muscle of rabbits. Arch. Phys. Med. Rehabil. 78: 512-517.
27. Sargeant, A.J., Davies, C.T., Edwards, R.H., Maunder, C. and Young, A. 1977. Functional and structural changes after disuse of human muscle. Clin. Sci. Mol. Med. 52: 337-342.
28. Shen, V., Liang, X.G., Birchman, R., Wu, D.D., Healy, D., Lindsay, R. and Dempster, D.W. 1997. Short-term immobilization-induced cancellous bone loss is limited to regions undergoing high turnover and/or modeling in mature rats. Bone 21: 71-78.
29. Weinreb, M., Rodan, G.A., and Thompson, D.D. 1991. Depression of osteoblastic activity in immobilized limbs of suckling rats. J. Bone Miner Res. 6: 725-731.
30. Whedon, G.D. 1984. Disuse osteoporosis: physiological aspects. Calcif. Tissue Int. 36 (Suppl 1): S146-150.
31. Zeng, Q.Q., Jee, W.S., Bigornia, A.E., King, J.G. Jr., D'Souza, S.M., Li, X.J., Ma, Y.F. and Wechter, W.J. 1996. Time responses of cancellous and cortical bones to sciatic neurectomy in growing female rats. Bone 19:13-21.