-
1
-
-
0037421590
-
Pharmacogenomics-drug disposition, drug targets, and side effects
-
Evans WE, McLeod HL (2003) Pharmacogenomics-drug disposition, drug targets, and side effects. N Engl J Med 348:538-549
-
(2003)
N Engl J Med
, vol.348
, pp. 538-549
-
-
Evans, W.E.1
McLeod, H.L.2
-
2
-
-
0037362122
-
Implications of pharmacogenetics for individualizing drug treatment and for study design
-
Meisel C, Gerloff T, Kirchheiner J, Mrozikiewicz PM, Niewinski P, Brockmoller J, Roots I (2003) Implications of pharmacogenetics for individualizing drug treatment and for study design. J Mol Med 81:154-167
-
(2003)
J Mol Med
, vol.81
, pp. 154-167
-
-
Meisel, C.1
Gerloff, T.2
Kirchheiner, J.3
Mrozikiewicz, P.M.4
Niewinski, P.5
Brockmoller, J.6
Roots, I.7
-
3
-
-
0037184841
-
Genetic polymorphisms of UDP-glucuronosyltransferases and their functional significance
-
Miners JO, McKinnon RA, Mackenzie PI (2002) Genetic polymorphisms of UDP-glucuronosyltransferases and their functional significance. Toxicology 181-182:453-456
-
(2002)
Toxicology
, vol.181-182
, pp. 453-456
-
-
Miners, J.O.1
McKinnon, R.A.2
Mackenzie, P.I.3
-
4
-
-
0037230622
-
Inherited disorders of bilirubin metabolism
-
Bosma PJ (2003) Inherited disorders of bilirubin metabolism. J Hepatol 38:107-117
-
(2003)
J Hepatol
, vol.38
, pp. 107-117
-
-
Bosma, P.J.1
-
5
-
-
15244342411
-
UDP-glucuronosyltransferases and clinical drug-drug interactions
-
Kiang TK, Ensom MH, Chang TK (2005) UDP-glucuronosyltransferases and clinical drug-drug interactions. Pharmacol Ther 106:97-132
-
(2005)
Pharmacol Ther
, vol.106
, pp. 97-132
-
-
Kiang, T.K.1
Ensom, M.H.2
Chang, T.K.3
-
6
-
-
33749469029
-
Bilirubin metabolism and its disorders in hepatology
-
Zakim D, Boyer TD (eds). Saunders, Philadelphia
-
Chowdhury JR, Chowdhury NR, Jansen PLM (2003) Bilirubin metabolism and its disorders in hepatology. In: Zakim D, Boyer TD (eds) Hepatology: a textbook of liver disease, 4th edn. Saunders, Philadelphia, pp 233-270
-
(2003)
Hepatology: A Textbook of Liver Disease, 4th Edn.
, pp. 233-270
-
-
Chowdhury, J.R.1
Chowdhury, N.R.2
Jansen, P.L.M.3
-
7
-
-
0028867826
-
The genetic basis of the reduced expression of bilirubin UDP-glucuronosyltransferase 1 in Gilbert's syndrome
-
Bosma PJ, Chowdhury JR, Bakker C, Gantla S, de Boer A, Oostra BA, Lindhout D, Tytgat GN, Jansen PL, Oude Elferink RP (1995) The genetic basis of the reduced expression of bilirubin UDP-glucuronosyltransferase 1 in Gilbert's syndrome. N Engl J Med 333:1171-1175
-
(1995)
N Engl J Med
, vol.333
, pp. 1171-1175
-
-
Bosma, P.J.1
Chowdhury, J.R.2
Bakker, C.3
Gantla, S.4
De Boer, A.5
Oostra, B.A.6
Lindhout, D.7
Tytgat, G.N.8
Jansen, P.L.9
Oude Elferink, R.P.10
-
8
-
-
0034671387
-
Polymorphisms of UDP-glucuronosyltransferase gene and irinotecan toxicity: A pharmacogenetic analysis
-
Ando Y, Saka H, Ando M, Sawa T, Muro K, Ueoka H, Yokoyama A, Saitoh S, Shimokata K, Hasegawa Y (2000) Polymorphisms of UDP-glucuronosyltransferase gene and irinotecan toxicity: a pharmacogenetic analysis. Cancer Res 60:6921-6926
-
(2000)
Cancer Res
, vol.60
, pp. 6921-6926
-
-
Ando, Y.1
Saka, H.2
Ando, M.3
Sawa, T.4
Muro, K.5
Ueoka, H.6
Yokoyama, A.7
Saitoh, S.8
Shimokata, K.9
Hasegawa, Y.10
-
9
-
-
0024284028
-
A simple salting out procedure for extracting DNA from human nucleated cells
-
Miller SA, Dykes DD, Polesky HF (1988) A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 16:1215
-
(1988)
Nucleic Acids Res
, vol.16
, pp. 1215
-
-
Miller, S.A.1
Dykes, D.D.2
Polesky, H.F.3
-
10
-
-
23044502912
-
Pyrosequencing analysis of thrombosis-associated risk markers
-
Holmberg K, Persson ML, Uhlen M, Odeberg J (2005) Pyrosequencing analysis of thrombosis-associated risk markers. Clin Chem 51:1549-1552
-
(2005)
Clin Chem
, vol.51
, pp. 1549-1552
-
-
Holmberg, K.1
Persson, M.L.2
Uhlen, M.3
Odeberg, J.4
-
11
-
-
0036840861
-
Molecular haplotyping by pyrosequencing
-
1106, 1108
-
Odeberg J, Holmberg K, Eriksson P, Uhlen M (2002) Molecular haplotyping by pyrosequencing. Biotechniques 33:1104, 1106, 1108
-
(2002)
Biotechniques
, vol.33
, pp. 1104
-
-
Odeberg, J.1
Holmberg, K.2
Eriksson, P.3
Uhlen, M.4
-
12
-
-
0035071957
-
A new statistical method for haplotype reconstruction from population data
-
Stephens M, Smith NJ, Donnelly P (2001) A new statistical method for haplotype reconstruction from population data. Am J Hum Genet 68:978-989
-
(2001)
Am J Hum Genet
, vol.68
, pp. 978-989
-
-
Stephens, M.1
Smith, N.J.2
Donnelly, P.3
-
13
-
-
0029130796
-
Maximum-likelihood estimation of molecular haplotype frequencies in a diploid population
-
Excoffier L, Slatkin M (1995) Maximum-likelihood estimation of molecular haplotype frequencies in a diploid population. Mol Biol Evol 12:921-927
-
(1995)
Mol Biol Evol
, vol.12
, pp. 921-927
-
-
Excoffier, L.1
Slatkin, M.2
-
14
-
-
0029150074
-
A comparison of linkage disequilibrium measures for fine-scale mapping
-
Devlin B, Risch N (1995) A comparison of linkage disequilibrium measures for fine-scale mapping. Genomics 29:311-322
-
(1995)
Genomics
, vol.29
, pp. 311-322
-
-
Devlin, B.1
Risch, N.2
-
15
-
-
0034017850
-
GOLD-graphical overview of linkage disequilibrium
-
Abecasis GR, Cookson WO (2000) GOLD-graphical overview of linkage disequilibrium. Bioinformatics 16:182-183
-
(2000)
Bioinformatics
, vol.16
, pp. 182-183
-
-
Abecasis, G.R.1
Cookson, W.O.2
-
16
-
-
0014211361
-
Construction of phylogenetic trees
-
Fitch WM, Margoliash E (1967) Construction of phylogenetic trees. Science 155:279-284
-
(1967)
Science
, vol.155
, pp. 279-284
-
-
Fitch, W.M.1
Margoliash, E.2
-
17
-
-
0032493441
-
Racial variability in the UDP-glucuronosyltransferase 1 (UGT1A1) promoter: A balanced polymorphism for regulation of bilirubin metabolism?
-
Beutler E, Gelbart T, Demina A (1998) Racial variability in the UDP-glucuronosyltransferase 1 (UGT1A1) promoter: a balanced polymorphism for regulation of bilirubin metabolism? Proc Natl Acad Sci USA 95:8170-8174
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 8170-8174
-
-
Beutler, E.1
Gelbart, T.2
Demina, A.3
-
18
-
-
17044450136
-
Frequent co-occurrence of the TATA box mutation associated with Gilbert's syndrome (UGT1A1*28) with other polymorphisms of the UDP- glucuronosyltransferase-1 locus (UGT1A6*2 and UGT1A7*3) in Caucasians and Egyptians
-
Kohle C, Mohrle B, Munzel PA, Schwab M, Wernet D, Badary OA Bock KW (2003) Frequent co-occurrence of the TATA box mutation associated with Gilbert's syndrome (UGT1A1*28) with other polymorphisms of the UDP- glucuronosyltransferase-1 locus (UGT1A6*2 and UGT1A7*3) in Caucasians and Egyptians. Biochem Pharmacol 65:1521-1527
-
(2003)
Biochem Pharmacol
, vol.65
, pp. 1521-1527
-
-
Kohle, C.1
Mohrle, B.2
Munzel, P.A.3
Schwab, M.4
Wernet, D.5
Badary, O.A.6
Bock, K.W.7
-
19
-
-
0032767352
-
UDP-glucuronosyltransferase (UGT1A1*28 and UGT1A6*2) polymorphisms in Caucasians and Asians: Relationships to serum bilirubin concentrations
-
Lampe JW, Bigler J, Horner NK, Potter JD (1999) UDP- glucuronosyltransferase (UGT1A1*28 and UGT1A6*2) polymorphisms in Caucasians and Asians: relationships to serum bilirubin concentrations. Pharmacogenetics 9:341-349
-
(1999)
Pharmacogenetics
, vol.9
, pp. 341-349
-
-
Lampe, J.W.1
Bigler, J.2
Horner, N.K.3
Potter, J.D.4
-
20
-
-
0031595660
-
The UGT1A1*28 allele is relatively rare in a Japanese population
-
Ando Y, Chida M, Nakayama K, Saka H, Kamataki T (1998) The UGT1A1*28 allele is relatively rare in a Japanese population. Pharmacogenetics 8:357-360
-
(1998)
Pharmacogenetics
, vol.8
, pp. 357-360
-
-
Ando, Y.1
Chida, M.2
Nakayama, K.3
Saka, H.4
Kamataki, T.5
-
21
-
-
0030699360
-
Genetic polymorphism in the human UGT1A6 (planar phenol) UDP-glucuronosyltransferase: Pharmacological implications
-
Ciotti M, Marrone A, Potter C, Owens IS (1997) Genetic polymorphism in the human UGT1A6 (planar phenol) UDP-glucuronosyltransferase: pharmacological implications. Pharmacogenetics 7:485-495
-
(1997)
Pharmacogenetics
, vol.7
, pp. 485-495
-
-
Ciotti, M.1
Marrone, A.2
Potter, C.3
Owens, I.S.4
-
22
-
-
0037230427
-
Combined polymorphisms in UDP-glucuronosyltransferases 1A1 and 1A6: Implications for patients with Gilbert's syndrome
-
Peters WH, te Morsche RH, Roelofs HM (2003) Combined polymorphisms in UDP-glucuronosyltransferases 1A1 and 1A6: implications for patients with Gilbert's syndrome. J Hepatol 38:3-8
-
(2003)
J Hepatol
, vol.38
, pp. 3-8
-
-
Peters, W.H.1
Te Morsche, R.H.2
Roelofs, H.M.3
-
23
-
-
0032847365
-
Molecular genetic basis of Gilbert's syndrome
-
Burchell B, Hume R (1999) Molecular genetic basis of Gilbert's syndrome. J Gastroenterol Hepatol 14:960-966
-
(1999)
J Gastroenterol Hepatol
, vol.14
, pp. 960-966
-
-
Burchell, B.1
Hume, R.2
-
24
-
-
33749496255
-
Hyperbilirubinaemia
-
McIntyre N, Benhamou J, Bircher J et al. (eds). Oxford University Press, Oxford
-
Fever JP, Blanckaert N (1991) Hyperbilirubinaemia. In: McIntyre N, Benhamou J, Bircher J et al. (eds) Oxford textbook of clinical hepatology. Oxford University Press, Oxford, pp 985-991
-
(1991)
Oxford Textbook of Clinical Hepatology
, pp. 985-991
-
-
Fever, J.P.1
Blanckaert, N.2
-
25
-
-
0026648833
-
Sex- and race-related differences in liver-associated serum chemistry tests in young adults in the CARDIA study
-
Manolio TA, Burke GL, Savage PJ, Jacobs DR Jr, Sidney S, Wagenknecht LE, Allman RM, Tracy RP (1992) Sex- and race-related differences in liver-associated serum chemistry tests in young adults in the CARDIA study. Clin Chem 38:1853-1859
-
(1992)
Clin Chem
, vol.38
, pp. 1853-1859
-
-
Manolio, T.A.1
Burke, G.L.2
Savage, P.J.3
Jacobs Jr., D.R.4
Sidney, S.5
Wagenknecht, L.E.6
Allman, R.M.7
Tracy, R.P.8
-
26
-
-
0021669755
-
Sex- and age-related differences in bilirubin concentrations in serum
-
Rosenthal P, Pincus M, Fink D (1984) Sex- and age-related differences in bilirubin concentrations in serum. Clin Chem 30:1380-1382
-
(1984)
Clin Chem
, vol.30
, pp. 1380-1382
-
-
Rosenthal, P.1
Pincus, M.2
Fink, D.3
-
27
-
-
2342459714
-
Genetic variants in the UDP-glucuronosyltransferase 1A1 gene predict the risk of severe neutropenia of irinotecan
-
Innocenti F, Undevia SD, Iyer L, Chen PX, Das S, Kocherginsky M, Karrison T, Janisch L, Ramirez J, Rudin CM, Vokes EE, Ratain MJ (2004) Genetic variants in the UDP-glucuronosyltransferase 1A1 gene predict the risk of severe neutropenia of irinotecan. J Clin Oncol 22:1382-1388
-
(2004)
J Clin Oncol
, vol.22
, pp. 1382-1388
-
-
Innocenti, F.1
Undevia, S.D.2
Iyer, L.3
Chen, P.X.4
Das, S.5
Kocherginsky, M.6
Karrison, T.7
Janisch, L.8
Ramirez, J.9
Rudin, C.M.10
Vokes, E.E.11
Ratain, M.J.12
-
28
-
-
0030800075
-
Differential expression of the UGT1A locus in human liver, biliary, and gastric tissue: Identification of UGT1A7 and UGT1A10 transcripts in extrahepatic tissue
-
Strassburg CP, Oldhafer K, Manns MP, Tukey RH (1997) Differential expression of the UGT1A locus in human liver, biliary, and gastric tissue: identification of UGT1A7 and UGT1A10 transcripts in extrahepatic tissue. Mol Pharmacol 52:212-220
-
(1997)
Mol Pharmacol
, vol.52
, pp. 212-220
-
-
Strassburg, C.P.1
Oldhafer, K.2
Manns, M.P.3
Tukey, R.H.4
-
29
-
-
0036765309
-
Common human UGT1A polymorphisms and the altered metabolism of irinotecan active metabolite 7-ethyl-10-hydroxycamptothecin (SN-38)
-
Gagne JF, Montminy V, Belanger P, Journault K, Gaucher G, Guillemette C (2002) Common human UGT1A polymorphisms and the altered metabolism of irinotecan active metabolite 7-ethyl-10-hydroxycamptothecin (SN-38). Mol Pharmacol 62:608-617
-
(2002)
Mol Pharmacol
, vol.62
, pp. 608-617
-
-
Gagne, J.F.1
Montminy, V.2
Belanger, P.3
Journault, K.4
Gaucher, G.5
Guillemette, C.6
-
30
-
-
0034778246
-
Human liver UDP-glucuronosyltransferase isoforms involved in the glucuronidation of 7-ethyl-10-hydroxycamptothecin
-
Hanioka N, Ozawa S, Jinno H, Ando M, Saito Y, Sawada J (2001) Human liver UDP-glucuronosyltransferase isoforms involved in the glucuronidation of 7-ethyl-10-hydroxycamptothecin. Xenobiotica 31:687-699
-
(2001)
Xenobiotica
, vol.31
, pp. 687-699
-
-
Hanioka, N.1
Ozawa, S.2
Jinno, H.3
Ando, M.4
Saito, Y.5
Sawada, J.6
|