Treatment with trimethyltin promotes the formation of cleaved tau in the rat brain

Journal of Neuroscience Research

Volumn 84, Issue 5, 2006, Pages 1116-1123

  Straiko, M M W ^a   Gudelsky, G A ^a   Coolen, L M ^a   Harrison, R ^b   Zemlan, F P ^b  

^a UNIVERSITY OF CINCINNATI   (United States)

^b UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

Author keywords

Astrocytes; GFAP; Neurotoxicity

Indexed keywords

GLIAL FIBRILLARY ACIDIC PROTEIN; TAU PROTEIN; TRIMETHYLTIN;

ANIMAL TISSUE; ARTICLE; ASTROCYTE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; HIPPOCAMPUS; IMMUNOBLOTTING; IMMUNOCYTOCHEMISTRY; MALE; MESENCEPHALON; NERVOUS SYSTEM INJURY; NONHUMAN; PRIORITY JOURNAL; PYRIFORM CORTEX; RAT;

ANIMALS; BLOTTING, WESTERN; BRAIN; ENZYME-LINKED IMMUNOSORBENT ASSAY; GLIAL FIBRILLARY ACIDIC PROTEIN; IMMUNOHISTOCHEMISTRY; MALE; NEUROTOXINS; RATS; RATS, LONG-EVANS; TAU PROTEINS; TIME FACTORS; TRIMETHYLTIN COMPOUNDS;

EID: 33749487031     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.21002     Document Type: Article

References (32)

1. Andersson H, Luthman J, Lindqvist E, Olson L. 1995. Time-course of trimethyltin effects on the monoaminergic systems of the rat brain. Neurotoxicology 16:201-210.
2. Balaban CD, O'Callaghan JP, Billingsley ML. 1988. Trimethyltin-induced neuronal damage in the rat brain: comparative studies using silver degeneration stains, immunocytochemistry and immunoassay for neuronotypic and gliotypic proteins. Neuroscience 26:337-361.
3. Bloom GS, Schoenfeld TA, Vallee RB. 1984. Widespread distribution of the major polypeptide component of MAP 1 (microtubule-associated protein 1) in the nervous system. J Cell Biol 98:320-330.
4. Bouldin TW, Goines ND, Bagnell RC, Krigman MR. 1981. Pathogenesis of trimethyltin neuronal toxicity. Ultrastructural and cytochemical observations. Am J Pathol 104:237-249.
5. Brock TO, O'Callaghan JP. 1987. Quantitative changes in the synaptic vesicle proteins synapsin I and p38 and the astrocyte-specific protein glial fibrillary acidic protein are associated with chemical-induced injury to the rat central nervous system. J Neurosci 7:931-942.
6. Brown AW, Aldridge WN, Street BW, Verschoyle RD. 1979. The behavioral and neuropathologic sequelae of intoxication by trimethyltin compounds in the rat. Am J Pathol 97:59-82.
7. Caceres A, Binder LI, Payne MR, Bender P, Rebhun L, Steward O. 1984. Differential subcellular localization of tubulin and the microtubule-associated protein MAP2 in brain tissue as revealed by immunocytochemistry with monoclonal hybridoma antibodies. J Neurosci 4:394-410.
8. Chang LW, Dyer RS. 1983. A time-course study of trimethyltin induced neuropathology in rats. Neurobehav Toxicol Teratol 5:443-459.
9. Dyer RS, Walsh TJ, Wonderlin WF, Bercegeay M. 1982. The trimethyltin syndrome in rats. Neurobehav Toxicol Teratol 4:127-133.
10. Fortemps E, Amand G, Bomboir A, Lauwerys R, Laterre EC. 1978. Trimethyltin poisoning. Report of two cases. Int Arch Occup Environ Health 41:1-6.
11. Gabbita SP, Scheff SW, Menard RM, Roberts K, Fugaccia I, Zemlan FP. 2005. Cleaved-tau: a biomarker of neuronal damage after traumatic brain injury. J Neurotrauma 22:83-94.
12. Goedert M, Spillantini MG, Jakes R, Rutherford D, Crowther RA. 1989. Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease. Neuron 3:519-526.
13. Haga S, Haga C, Aizawa T, Ikeda K. 2002. Neuronal degeneration and glial cell-responses following trimethyltin intoxication in the rat. Acta Neuropathol 103:575-582.
14. Hagan JJ, Jansen JH, Broekkamp CL. 1988. Selective behavioural impairment after acute intoxication with trimethyltin (TMT) in rats. Neurotoxicology 9:53-74.
15. Irazuzta JE, de Courten-Myers G, Zemlan FP, Bekkedal MY, Rossi J 3rd. 2001. Serum cleaved tau protein and neurobehavioral battery of tests as markers of brain injury in experimental bacterial meningitis. Brain Res 913:95-105.
16. Ishikawa K, Kubo T, Shibanoki S, Matsumoto A, Hata H, Asai S. 1997. Hippocampal degeneration inducing impairment of learning in rats: model of dementia? Behav Brain Res 83:39-44.
17. Koczyk D, Oderfeld-Nowak B. 2000. Long-term microglial and astroglial activation in the hippocampus of trimethyltin-intoxicated rat: stimulation of NGF and TrkA immunoreactivities in astroglia but not in microglia. Int J Dev Neurosci 18:591-606.
18. Little AR, Benkovic SA, Miller DB, O'Callaghan JP. 2002. Chemically induced neuronal damage and gliosis: enhanced expression of the proinflammatory chemokine, monocyte chemoattractant protein (MCP)-1, without a corresponding increase in proinflammatory cytokines (1). Neuroscience 115:307-320.
19. LoPresti P, Szuchet S, Papasozomenos SC, Zinkowski RP, Binder LI. 1995. Functional implications for the microtubule-associated protein tau: localization in oligodendrocytes. Proc Natl Acad Sci U S A 92:10369-10373.
20. Maier WE, Brown HW, Tilson HA, Luster MI, Harry GJ. 1995. Trimethyltin increases interleukin (IL)-1 alpha, IL-6 and tumor necrosis factor alpha mRNA levels in rat hippocampus. J Neuroimmunol 59:65-75.
21. McCann MJ, O'CaUaghan JP, Martin PM, Bertram T, Streit WJ. 1996. Differential activation of microglia and astrocytes following trimethyl tin-induced neurodegeneration. Neuroscience 72:273-281.
22. Ross WD, Emmett EA, Steiner J, Tureen R. 1981. Neurotoxic effects of occupational exposure to organotins. Am J Psychiatry 138:1092-1095.
23. Scallet AC, Pothuluri N, Rountree RL, Matthews JC. 2000. Quantitating silver-stained neurodegeneration: the neurotoxicity of trimethlytin (TMT) in aged rats. J Neurosci Methods 98:69-76.
24. Shaw GJ, Jauch EC, Zemlan FP. 2002. Serum cleaved tau protein levels and clinical outcome in adult patients with closed head injury. Ann Emerg Med 39:254-257.
25. Swanson L. 1998. Brain maps: structure of the rat brain. New York: Elsevier.
26. Wallace TL, Vorhees CV, Zemlan FP, Gudelsky GA. 2003. Methamphetamine enhances the cleavage of the cytoskeletal protein tau in the rat brain. Neuroscience 116:1063-1068.
27. Watson RE Jr, Wiegand SJ, Clough RW, Hoffman GE. 1986. Use of cryoprotectant to maintain long-term peptide immunoreactivity and tissue morphology. Peptides 7:155-159.
28. Whittington DL, Woodruff ML, Baisden RH. 1989. The time-course of trimethyltin-induced fiber and terminal degeneration in hippocampus. Neurotoxicol Teratol 11:21-33.
29. Yoshiyama Y, Zhang B, Bruce J, Trojanowski JQ, Lee VM. 2003. Reduction of detyrosinated microtubules and Golgi fragmentation are linked to tau-induced degeneration in astrocytes. J Neurosci 23:10662-10671.
30. Zemlan FP, Rosenberg WS, Luebbe PA, Campbell TA, Dean GE, Weiner NE, Cohen JA, Rudick RA, Woo D. 1999. Quantification of axonal damage in traumatic brain injury: affinity purification and characterization of cerebrospinal fluid tau proteins. J Neurochem 72:741-750.
31. Zemlan FP, Jauch EC, Mulchahey JJ, Gabbita SP, Rosenberg WS, Speciale SG, Zuccarello M. 2002. C-tau biomarker of neuronal damage in severe brain injured patients: association with elevated intracranial pressure and clinical outcome. Brain Res 947:131-139.
32. Zemlan FP, Mulchahey JJ, Gudelsky GA. 2003. Quantification and localization of kainic acid-induced neurotoxicity employing a new biomarker of cell death: cleaved microtubule-associated protein-tau (C-tau). Neuroscience 121:399-409.