Gene expression and protein localization of calmodulin-dependent phosphodiesterase in adult rat retina

Journal of Neuroscience Research

Volumn 84, Issue 5, 2006, Pages 1020-1026

  Santone, Rocco ^a   Giorgi, Mauro ^a   Maccarone, Rita ^a   Basso, Manuela ^a,b   Deplano, Stefania ^b   Bisti, Silvia ^a  

^a UNIVERSITY OF L'AQUILA   (Italy)

^b UNIVERSITY OF GENOA   (Italy)

Author keywords

Calmodulin; Calmodulin dependent phosphodiesterase; Choline acetyltransferase; Retina

Indexed keywords

CALMODULIN DEPENDENT PHOSPHODIESTERASE 1A ENZYME; CALMODULIN DEPENDENT PHOSPHODIESTERASE 1B ENZYME; CALMODULIN DEPENDENT PHOSPHODIESTERASE 1C ENZYME; CALMODULIN DEPENDENT PHOSPHODIESTERASE ENZYME; CHOLINE ACETYLTRANSFERASE ANTIBODY; CYCLIC AMP; CYCLIC GMP; ENZYME ANTIBODY; GENE PRODUCT; ISOENZYME; PDE1A ANTIBODY; PDE1B ANTIBODY; PDE1C ANTIBODY; PHOSPHODIESTERASE I; UNCLASSIFIED DRUG;

ACCURACY; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME LOCALIZATION; FLUORESCENCE; GENE EXPRESSION; IMMUNOHISTOCHEMISTRY; MOLECULAR WEIGHT; NONHUMAN; NUCLEOTIDE SEQUENCE; PHOTORECEPTOR; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RAT; RETINA; RETINA AMACRINE CELL; RETINA CELL;

3',5'-CYCLIC-AMP PHOSPHODIESTERASES; 3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE; ANIMALS; BLOTTING, WESTERN; CHROMATOGRAPHY, ION EXCHANGE; CYCLIC NUCLEOTIDE PHOSPHODIESTERASES, TYPE 1; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; IMMUNOHISTOCHEMISTRY; RATS; RATS, LONG-EVANS; RETINA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 33749472544     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.21009     Document Type: Article

References (31)

1. Beavo JA. 1995. Cyclic nucleotide phosphodiesterases: functional implications of multiple isoforms. Physiol Rev 75:725-748.
2. Beavo JA, Bruton LL. 2002. Cyclic nucleotide research: still expanding after half a century. Nat Rev Mol Cell Biol 3:710-718.
3. Cervetto L, Lagnado L, Perry R, Robinson DW, McNaughton PA. 1989. Extrusion of calcium from rod out segments is driven by sodium potassium gradients. Nature 337:740-743.
4. Chapman B. 2000. Necessity for afferent activity to maintain eye-specific segregation in ferret lateral geniculate nucleus. Science 287:2479-2482.
5. Feller MB. 2002. The role of nAChR-mediated spontaneous retinal activity in visual system development. J Neurobiol 53:556-567.
6. Gillespie PG. 1990. Phosphodiesterase in visual transduction by rods and cones. In: Beavo J, Houslay MD, editors. Cyclic nucleotide phosphodiesterases: structure, regulation and drug action. New York: Wiley. p 163-184.
7. Giorgi M, Giordano D, Rosati J, Tata AM, Augusti-Tocco G. 2002. Differential expression and localization of calmodulin-dependent phosphodiesterase genes during ontogenesis of chick dorsal root ganglion. J Neurochem 80:970-979.
8. Giorgi M, Basso M, Deplano S, Nuccetelli V, Maccarone R, Bisti S. 2005. Expression and localization of calmodulin-dependent phosphodiesterase genes in rat retina. Abstr Ital Soc Neurosci (in press).
9. Krizaj D, Copenhagen DR. 2002. Calcium regulation in photoreceptors. Front Biosci 7:2023-2044.
10. Laemmli UK. 1970. Cleavage of structural protein during the assembly of bacteriophage T4. Nature 227:680-685.
11. Lefièvre L, de Lamirande E, Gagnon C. 2002. Presence of cyclic nucleotide phosphodiesterases PDE1A, existing as a stable complex with calmodulin, and PDE3A in human spermatozoa. Biol Reprod 67:423-430.
12. Lowry O, Rosembrough NJ, Farr AR, Randall RJ. 1951. Protein measurement with the folic phenol reagent. J Biol Chem 193:265-275.
13. 2+/calmodulin-dependent phosphodiesterase PDE1A: novel splice variants, their specific expression, genomic organization, and chromosomal localization. Biochim Biophys Acta 1517:278-287.
14. 2+ through cGMP-gated ion channels of intact rod and cone photoreceptors. J Gen Physiol 116:735-754.
15. Polli JW, Kincaid RL. 1994. Expression of a calmodulin-dependent phosphodiesterase isoform (PDE1B) correlates with brain regions having extensive dopaminergic innervations. J Neurochem 14:1251-1261.
16. Pugh EN, Lamb TD. 1993. Amplification and kinetics of the activation steps in phototransduction. Biochim Biophys Acta 1141:111-149.
17. Sharma RK, Tan Y, Raju RVS. 1997. Calmodulin-dependent cyclic nucleotide phosphodiesterase from bovine eye: high calmodulin affinity isoenzyme immunologically related to the brain 60-kDa isoenzyme. Arch Biochem Biophys 339:40-46.
18. Sharma RK, Seitz DP, Singh B, Tan Y. 2002. Localization and regulation of bovine eye calmodulin-dependent cyclic nucleotide phosphodiesterase by cyclic AMP-dependent protein kinase. Int J Mol Med 10:17-23.
19. Siegelbaum SA, Schwartz JH. 2000. Modulation of synaptic transmission: second messengers. In: Kandel ER, Schwartz JH, Jessell TM, editors. Principles of neural science. New York: McGraw Hill, p 229-252.
20. Soderling SH, Beavo JA. 2000. Regulation of cAMP and cGMP signaling: new phosphodiesterases and new functions. Curr Opin Cell Biol 12:174-179.
21. Stellwagen D, Shatz CJ, Feller MB. 1999. Dynamics of retinal waves are controlled by cyclic AMP. Neuron 24:673-685.
22. Stone J, Maslim J, Valter-Kocsi K, Mervin K, Bowers F, Chu Y, Barnett N, Provis J, Lewis G, Fisher SK, Bisti S, Gargini C, Cervetto L, Merin S, Pe'er J. 1999. Mechanisms of photoreceptor death and survival in mammalian retina. Prog Ret Eye Res 18:691-735.
23. Thompson WJ, Appleman MM. 1971. Multiple cyclic nucleotide phosphodiesterase activities from rat brain. Biochemistry 10:311-316.
24. Towbin H, Staehelin T, Gordon J. 1979. Electrophoretic transfer of protein from polyacrylamide gels to nitrocellulose sheets: procedure and some applications. Proc Natl Acad Sci U S A 76:4350-4354.
25. White JB, Thompson WJ, Pittler SJ. 2004 Characterization of 3′,5′ cyclic nucleotide phosphodiesterase activity in Y79 retinoblastoma cells: absence of functional PDE6. Mol Vis 10:738-749.
26. Wong ROL. 1999. Retinal waves and visual system development. Annu Rev Neurosci 22:29-47.
27. Yan C, Bentley JK, Sonnenburg WK, Beavo JA. 1994. Differential expression of the 61 kDa and 63 kDa calmodulin-dependent phosphodiesterases in the mouse brain. J Neurosci 14:973-984.
28. Yan C, Zhao AZ, Bentley JK, Beavo JA. 1996. The calmodulin-dependent phosphodiesterase gene PDE1C encodes several functionally different splice variants in a tissue-specific manner. J Biol Chem 271:25699-25706.
29. 2+/CaM-activated phosphodiesterase. Adv Second Messenger Phosphoprot Res 31:237-251.
30. Zhou ZJ. 2001. The function of the cholinergic system in the developing mammalian retina. Prog Brain Res 131:599-613.
31. Zucker CL, Ehinger B. 2001 Complexities of retinal circuitry revealed by neurotransmitter receptor localization. Prog Brain Res 131:71-81.