Utility of a New Model to Diagnose an Alcohol Basis for Steatohepatitis

Gastroenterology

Volumn 131, Issue 4, 2006, Pages 1057-1063

  Dunn, Winston ^a   Angulo, Paul ^a   Sanderson, Schuyler ^a   Jamil, Laith H ^a   Stadheim, Linda ^a   Rosen, Charles ^a   Malinchoc, Michael ^a   Kamath, Patrick S ^a   Shah, Vijay H ^a  

^a MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; BIOLOGICAL MARKER; CARBOHYDRATE DEFICIENT TRANSFERRIN; GAMMA GLUTAMYLTRANSFERASE; PROTEIN TYROSINE PHOSPHATASE;

ADULT; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALCOHOLIC FATTY LIVER; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BODY MASS; COHORT ANALYSIS; FEMALE; GAMMA GLUTAMYL TRANSFERASE BLOOD LEVEL; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; MEAN CORPUSCULAR VOLUME; MULTIVARIATE LOGISTIC REGRESSION ANALYSIS; NONALCOHOLIC FATTY LIVER; PRIORITY JOURNAL;

EID: 33749365193     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.gastro.2006.08.020     Document Type: Article

References (28)

1. Said A., Williams J., Holden J., Remington P., Musat A., and Lucey M.R. The prevalence of alcohol-induced liver disease and hepatitis C and their interaction in a tertiary care setting. Clin Gastroenterol Hepatol 2 (2004) 928-934
2. Mofrad P., Contos M.J., Haque M., Sargeant C., Fisher R.A., Luketic V.A., Sterling R.K., Shiffman M.L., Stravitz R.T., and Sanyal A.J. Clinical and histologic spectrum of nonalcoholic fatty liver disease associated with normal ALT values. Hepatology 37 (2003) 1286-1292
3. Kunde S.S., Lazenby A.J., Clements R.H., and Abrams G.A. Spectrum of NAFLD and diagnostic implications of the proposed new normal range for serum ALT in obese women. Hepatology 42 (2005) 650-656
4. Akriviadis E., Botla R., Briggs W., Han S., Reynolds T., and Shakil O. Pentoxifylline improves short-term survival in severe acute alcoholic hepatitis: a double-blind, placebo-controlled trial. Gastroenterology 119 (2000) 1637-1648
5. Carithers R.J., Herlong H., Diehl A., Shaw E., Combes B., Fallon H., and Maddrey W. Methylprednisolone therapy in patients with severe alcoholic hepatitis. A randomized multicenter trial. (comments). Ann Intern Med 110 (1989) 685-690
6. Arteel G., Marsano L., Mendez C., Bentley F., and McClain C.J. Advances in alcoholic liver disease. Best Pract Res Clin Gastroenterol 17 (2003) 625-647
7. Marsano L.S., Mendez C., Hill D., Barve S., and McClain C.J. Diagnosis and treatment of alcoholic liver disease and its complications. Alcohol Res Health 27 (2003) 247-256
8. Zhou Z., Wang L., Song Z., Saari J.T., McClain C.J., and Kang Y.J. Zinc supplementation prevents alcoholic liver injury in mice through attenuation of oxidative stress. Am J Pathol 166 (2005) 1681-1690
9. Morgan T.R., Weiss D.G., Nemchausky B., Schiff E.R., Anand B., Simon F., Kidao J., Cecil B., Mendenhall C.L., Nelson D., Lieber C., Pedrosa M., Jeffers L., Bloor J., Lumeng L., Marsano L., McClain C., Mishra G., Myers B., Leo M., Ponomarenko Y., Taylor D., Chedid A., French S., Kanel G., Murray N., Pinto P., Fong T.L., and Sather M.R. Colchicine treatment of alcoholic cirrhosis: a randomized, placebo-controlled clinical trial of patient survival. Gastroenterology 128 (2005) 882-890
10. McCullough A.J. The clinical features, diagnosis and natural history of nonalcoholic fatty liver disease. Clin Liver Dis 8 (2004) 521-533 viii
11. Diehl A.M., Goodman Z., and Ishak K.G. Alcohol-like liver disease in nonalcoholics. A clinical and histologic comparison with alcohol-induced liver injury. Gastroenterology 95 (1988) 1056-1062
12. Salaspuro M. Carbohydrate-deficient transferrin as compared to other markers of alcoholism: a systematic review. Alcohol 19 (1999) 261-271
13. Mundle G., Ackermann K., Munkes J., Steinle D., and Mann K. Influence of age, alcohol consumption and abstinence on the sensitivity of carbohydrate-deficient transferrin, γ-glutamyltransferase and mean corpuscular volume. Alcohol 34 (1999) 760-766
14. Sanderson S.O., and Smyrk T.C. The use of protein tyrosine phosphatase 1B and insulin receptor immunostains to differentiate nonalcoholic from alcoholic steatohepatitis in liver biopsy specimens. Am J Clin Pathol 123 (2005) 503-509
15. Adams L.A., Sanderson S., Lindor K.D., and Angulo P. The histological course of nonalcoholic fatty liver disease: a longitudinal study of 103 patients with sequential liver biopsies. J Hepatol 42 (2005) 132-138
16. Angulo P., Keach J.C., Batts K.P., and Lindor K.D. Independent predictors of liver fibrosis in patients with nonalcoholic steatohepatitis. Hepatology 30 (1999) 1356-1362
17. Dunn W., Jamil L.H., Brown L.S., Wiesner R.H., Kim W.R., Menon K.V., Malinchoc M., Kamath P.S., and Shah V. MELD accurately predicts mortality in patients with alcoholic hepatitis. Hepatology 41 (2005) 353-358
18. Stadheim L.M., O'Brien J.F., Lindor K.D., Gores G.J., and McGill D.B. Value of determining carbohydrate-deficient transferrin isoforms in the diagnosis of alcoholic liver disease. Mayo Clin Proc 78 (2003) 703-707
19. Kamath P., Wiesner R., Malinchoc M., Kremers W., Therneau T., Kosberg C., D'Amico G., Dickson E., and Kim W. A model to predict survival in patients with end-stage liver disease. Hepatology 33 (2001) 464-470
20. DeLong E.R., DeLong D.M., and Clarke-Pearson D.L. Comparing the areas under two or more correlated receiver operating characteristic curves: a nonparametric approach. Biometrics 44 (1988) 837-845
21. Lumeng L. New diagnostic markers of alcohol abuse. Hepatology 6 (1986) 742-745
22. Menon K., Gores G., and Shah V. Pathogenesis, diagnosis, and treatment of alcoholic liver disease. Mayo Clin Proc 76 (2001) 1021-1029
23. Sorbi D., Boynton J., and Lindor K.D. The ratio of aspartate aminotransferase to alanine aminotransferase: potential value in differentiating nonalcoholic steatohepatitis from alcoholic liver disease. Am J Gastroenterol 94 (1999) 1018-1022
24. Nyblom H., Berggren U., Balldin J., and Olsson R. High AST/ALT ratio may indicate advanced alcoholic liver disease rather than heavy drinking. Alcohol Alcohol 39 (2004) 336-339
25. Nalpas B., Hispard E., Thepot V., Pot S., Dally S., and Berthelot P. A comparative study between carbohydrate-deficient transferrin and γ-glutamyltransferase for the diagnosis of excessive drinking in a liver unit. J Hepatol 27 (1997) 1003-1008
26. Pinto H.C., Baptista A., Camilo M.E., Valente A., Saragoca A., and de Moura M.C. Nonalcoholic steatohepatitis. Clinicopathological comparison with alcoholic hepatitis in ambulatory and hospitalized patients. Dig Dis Sci 41 (1996) 172-179
27. Bedogni G., Miglioli L., Masutti F., Tiribelli C., Marchesini G., and Bellentani S. Prevalence of and risk factors for nonalcoholic fatty liver disease: the Dionysos nutrition and liver study. Hepatology 42 (2005) 44-52
28. Balasubramanian S., and Kowdley K.V. Effect of alcohol on viral hepatitis and other forms of liver dysfunction. Clin Liver Dis 9 (2005) 83-101