Raf-1 kinase activation is uncoupled from downstream MEK/ERK pathway in cells treated with Src tyrosine kinase inhibitor PP2

Biochemical and Biophysical Research Communications

Volumn 350, Issue 2, 2006, Pages 450-456

  Lee, Michael ^a  

^a SolarLight Ltd   (South Korea)

Author keywords

MAPK pathway; PP2; Raf 1 kinase; siRNA; Sprouty proteins; Src tyrosine kinase

Indexed keywords

4 AMINO 7 TERT BUTYL 5 (4 CHLOROPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; HYDROGEN PEROXIDE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PHORBOL 13 ACETATE 12 MYRISTATE; RAF PROTEIN; RAS PROTEIN; SMALL INTERFERING RNA;

ANIMAL CELL; ARTICLE; CELL GROWTH; COMPARATIVE STUDY; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; FEEDBACK SYSTEM; GROWTH INHIBITION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SENSITIVITY ANALYSIS; SIGNAL TRANSDUCTION;

ANIMALS; CELL PROLIFERATION; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; MAP KINASE SIGNALING SYSTEM; MICE; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; NIH 3T3 CELLS; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHOPROTEINS; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS C-RAF; PYRIMIDINES; RNA INTERFERENCE; SRC-FAMILY KINASES;

EID: 33749354298     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2006.09.067     Document Type: Article

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