The N-terminal transmembrane domain (TMD0) and a cytosolic linker (L0) of sulphonylurea receptor define the unique intrinsic gating of KATP channels

Journal of Physiology

Volumn 576, Issue 2, 2006, Pages 379-389

  Fang, Kun ^a   Csanády, László ^b   Chan, Kim W ^a  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b SEMMELWEIS UNIVERSITY   (Hungary)

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER; ADENOSINE TRIPHOSPHATASE (POTASSIUM); POTASSIUM CHANNEL; SULFONYLUREA RECEPTOR; ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR6.2; SULFONYLUREA RECEPTOR 1; SULFONYLUREA RECEPTOR 2A; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CELL MEMBRANE; CELL MEMBRANE TRANSPORT; CHANNEL GATING; CHIMERA; CYTOSOL; ENDOPLASMIC RETICULUM; KINETICS; MOLECULAR BIOLOGY; NONHUMAN; OOCYTE; PATCH CLAMP; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; WILD TYPE; XENOPUS; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CYTOSOLIC LINKER; FEMALE; N TERMINAL TRANSMEMBRANE DOMAIN; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE;

ANIMALS; ATP-BINDING CASSETTE TRANSPORTERS; CELLS, CULTURED; CHIMERA; CRICETINAE; ELECTROPHYSIOLOGY; FEMALE; ION CHANNEL GATING; MEMBRANE POTENTIALS; MICE; PATCH-CLAMP TECHNIQUES; POTASSIUM CHANNELS; POTASSIUM CHANNELS, INWARDLY RECTIFYING; PROTEIN STRUCTURE, TERTIARY; PROTEIN SUBUNITS; RATS; RECEPTORS, DRUG; XENOPUS LAEVIS;

EID: 33749354080     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2006.112748     Document Type: Article

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