Measuring serum procalcitonin in patients with fever in the ICU to differentiate infectious causes from non-infectious causes

Tuberculosis and Respiratory Diseases

Volumn 61, Issue 1, 2006, Pages 20-25

  Kim, Ho Cheol ^a   Kim, Kwang Min ^a   Lee, Sang Min ^a   Lee, Seung Jun ^a   Ham, Hyun Seok ^a   Cho, Yu Ji ^a   Jeong, Yi Yeong ^a   Lee, Jong Deok ^a   Hwang, Young Sil ^a  

^a Gyeongsang National University School of Medicine   (South Korea)

Author keywords

Fever; ICU; Procalcitonin

Indexed keywords

C REACTIVE PROTEIN; INTERLEUKIN 6; PROCALCITONIN; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; BACTERIAL INFECTION; CLINICAL ARTICLE; CONTROLLED STUDY; CULTURE TECHNIQUE; DISEASE COURSE; FEVER; HORMONE BLOOD LEVEL; HUMAN; INFECTION RISK; INTENSIVE CARE UNIT; LEUKOCYTE; LEUKOCYTE COUNT; PROSPECTIVE STUDY; PROTEIN BLOOD LEVEL;

EID: 33749348569     PISSN: 17383536     EISSN: None     Source Type: Journal    
DOI: 10.4046/trd.2006.61.1.20     Document Type: Article

References (28)

1. Marik PE. Fever in the ICU. Chest 2000;117:855-69.
2. Hatherill M, Tibby SM, Sykes K, Turner C, Murdoch IA. Diagnostic markers of infection: comparison of procalcitonin with C reactive protein and leucocyte count. Arch Dis Child 1999;81:417-21.
3. Karzai W, Oberhoffer M, Meier-Hellmann A, Reinhart K. Procalcitonin: a new indicator of the systemic response to severe infections. Infection 1997;25:329-34.
4. Assicot M, Gendrel D, Carsin H, Raymond J, Guilbaud J, Bohuon C. High serum procalcitonin concentrations in patients with sepsis and infection. Lancet 1993;341:515-8.
5. Simon L, Gauvin F, Amre DK, Saint-Louis P, Lacroix J. Serum procalcitonin and C-reactive protein levels as markers of bacterial infection: a systematic review and meta-analysis. Clin Infect Dis 2004;39:206-17.
6. Meisner M. Biomarkers of sepsis: clinically useful? Curr Opin Crit Care 2005;11:473-80.
7. BalcI C, Sungurtekin H, Gurses E, Sungurtekin U, Kaptanoglu B. Usefulness of procalcitonin for diagnosis of sepsis in the intensive care unit. Crit Care 2003;7:85-90.
8. Ugarte H, Silva E, Mercan D, de Mendonca A, Vincent JL. Procalcitonin used as a marker of infection in the intensive care unit. Crit Care Med 1999;27:498-504.
9. Muller B, Becker KL, Schachinger H, Rickenbacher PR, Huber PR, immerli W, et al. Calcitonin precursors are reliable markers of sepsis in a medical intensive care unit. Crit Care Med 2000;28:977-83.
10. Suprin E, Camus C, Gacouin A, le Tulzo Y, Lavoue S, Feuillu A, et al. Procalcitonin: a valuable indicator of infection in a medical ICU? Intensive Care Med 2000;26:1232-8.
11. Giamarellos-Bourboulis EJ, Mega A, Grecka P, Scarpa N, Koratzanis G, Thomopoulos G, et al. Procalcitonin: a marker to clearly differentiate systemic inflammatory response syndrome and sepsis in the critically ill patient? Intensive Care Med 2002;28:1351-6.
12. Johanson WG Jr, Pierce AK, Sanford JP, Thomas GD. Nosocomial respiratory infections with gram-negative bacilli: the significance of colonization of the respiratory tract. Ann Intern Med 1972;77:701-6.
13. Kelly CP, Pothoulakis C, LaMont JT. Clostridium difficile colitis. N Engl J Med 1994;330:257-62.
14. Raad I. Intravascular-catheter-related infections. Lancet 1998;351:893-8.
15. Garner JS, Jarvis WR, Emori TG, Horan TC, Hughes JM. CDC definitions for nosocomial infections, 1988. Am J Infect Control 1988;16:128-40.
16. Boeken U, Feindt P, Micek M, Petzold T, Schulte HD, Gams E. Procalcitonin (PCT) in cardiac surgery: diagnostic value in systemic inflammatory response syndrome (SIRS), sepsis and after heart transplantation (HTX). Cardiovasc Surg 2000;8:550-4.
17. Gerard Y, Hober D, Assicot M, Alfandari S, Ajana F, Bourez JM, et al. Procalcitonin as a marker of bacterial sepsis in patients infected with HIV-1. J Infect 1997;35:41-6.
18. Bernard L, Ferriere F, Casassus P, Malas F, Leveque S, Guillevin L, et al. Procalcitonin as an early marker of bacterial infection in severely neutropenic febrile adults. Clin Infect Dis 1998;27:914-5.
19. Harbarth S, Holeckova K, Froidevaux C, Pittet D, Ricou B, Grau GE, et al. Diagnostic value of procalcitonin, interleukin-6 and interleukin-8 in critically ill patients admitted with suspected sepsis. Am J Respir Crit Care Med 2001;164:396-402.
20. Meisner M, Tschaikowsky K, Hulzler A, Schick C, Schuttler J. Postoperative plasma concentrations of procalcitonin after different types of surgery. Intensive Care Med 1998;24:680-4.
21. Hensel M, Volk T, Docke WD, Kern F, Tschirna D, Egerer K, et al. Hyperprocalcitoninemia in patients with non-infectious SIRS and pulmonary dysfunction associated with cardiopulmonary bypass. Anesthesiology 1998;89:93-104.
22. Ghillani P, Motte P, Troalen F, Julienne A, Gardet P, le Chevalier T, et al. Identification and measurement of calcitonin precursors in serum of patients with malignant diseases. Cancer Res 1989;49:6845-51.
23. Bell K, Wattie M, Byth K, Silvestrini R, Clark P, Stachowski E, et al. Procalcitonin: a marker of bacteraemia in SIRS. Anaesth Intensive Care 2003;31:629-36.
24. Chirouze C, Schuhmacher H, Rabaud C, Gil H, Khayat N, Estavoyer JM, et al. Low serum procalcitanin level accurately predicts the absence of bacteremia in adult patients with acute fever. Clin Infect Dis 2002;35:156-61.
25. Meisner M, Tschaikowsky K, Palmaers T, Schmidt J. Comparison of procalcitonin (PCT) and C-reactive protein (CRP) plasma concentrations at different SOFA scores during the course of sepsis and MODS. Crit Care 1999;3:45-50.
26. Linscheid P, Seboek D, Schaer DJ, Zulewski H, Keller U, Muller B. Expression and secretion of procalcitonin and calcitonin gene-related peptide by adherent monocytes and macrophage-activated adipocytes. Crit Care Med 2004;32:1715-21.
27. O'Grady NP, Barie PS, Bartlett J, Bleck T, Garvey G, Jacobi J, et al. Practice parameters for evaluating new fever in critically ill adult patients. Crit Care Med 1998;26:392-408.
28. Van Zanten AR, Dixon JM, Nipshagen MD, de Bree R, Girbes AR, Polderman KH. Hospital-acquired sinusitis is a common cause of fever of unknown origin in orotracheally intubated critically ill patients. Crit Care 2005;9:R583-90.