Recent biochemical advances in white matter ischaemia

European Neurology

Volumn 56, Issue 2, 2006, Pages 74-77

  Alix, James J P ^a,b  

^a UNIVERSITY OF LEICESTER   (United Kingdom)

^b Maurice Shock Medical Sciences Building ^*  (United Kingdom)

Author keywords

Central nervous system; Ischaemia; White matter

Indexed keywords

MEMANTINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; SCAVENGER; TISSUE PLASMINOGEN ACTIVATOR;

BRAIN ISCHEMIA; CLINICAL TRIAL; COMPUTER ASSISTED TOMOGRAPHY; DRUG EFFECT; HUMAN; NEUROIMAGING; NEUROPROTECTION; NUCLEAR MAGNETIC RESONANCE IMAGING; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PROGNOSIS; REVIEW; STROKE; TREATMENT OUTCOME; WHITE MATTER; WHITE MATTER ISCHEMIA;

ANIMALS; BRAIN; BRAIN ISCHEMIA; HUMANS; NEUROPROTECTIVE AGENTS;

EID: 33749337846     PISSN: 00143022     EISSN: None     Source Type: Journal    
DOI: 10.1159/000095543     Document Type: Review

References (26)

1. Marcoux FW, Morawetz RB, Crowell RM, et al: Differential regional vulnerability in transient focal cerebral ischemia. Stroke 1982;13:339-346.
2. Pantoni L, Garcia JH, Gutierrez JA: Cerebral white matter is highly vulnerable to ischemia. Stroke 1996;27:1641-1646; discussion 1647.
3. Volpe JJ: Cerebral white matter injury of the premature infant - more common than you think. Pediatrics 2003;112:176-180.
4. Imamura K: Proton MR spectroscopy of the brain with a focus on chemical issues. Magn Reson Med Sci 2003;2:117-132.
5. Le Bihan D, van Zijl P: From the diffusion coefficient to the diffusion tensor. NMR Biomed 2002;15:431-434.
6. Reinges MH, Schoth F, Coenen VA, et al: Imaging of postthalamic visual fiber tracts by anisotropic diffusion-weighted MRI and diffusion tensor imaging: principles and applications. Eur J Radiol 2004;49:91-104.
7. 2+ exchanger. J Neurosci 1992;12:430-439.
8. 2+ channels and anoxic injury in rat CNS white matter. J Neurophysiol 2001;85:900-911.
9. Fern R, Ransom BR, Waxman SG: Voltage-gated calcium channels in CNS white matter: role in anoxic injury. J Neurophysiol 1995;74:369-377.
10. Fern R, Waxman SG, Ransom BR: Modulation of anoxic injury in CNS white matter by adenosine and interaction between adenosine and GABA. J Neurophysiol 1994;72:2609-2616.
11. 2+ channel activation of ryanodine receptors. Neuron 2003;40:53-63.
12. 2+ release and ischemic axon injury: the Trojan horse is back. Neuron 2003;40:2-4.
13. 2+ release in rat optic nerve during in vitro chemical ischemia. J Neurosci 2005;25:9960-9967.
14. Deng W, Rosenberg PA, Volpe JJ, Jensen FE: Calcium-permeable AMPA/kainate receptors mediate toxicity and preconditioning by oxygen-glucose deprivation in oligodendrocyte precursors. Proc Natl Acad Sci USA 2003;100:6801-6806.
15. Matute C, Sanchez-Gomez MV, Martinez-Millan L, et al: Glutamate receptor-mediated toxicity in optic nerve oligodendrocytes. Proc Natl Acad Sci USA 1997;94:8830-8835.
16. Salter MG, Fern R: NMDA receptors are expressed in developing oligodendrocyte processes and mediate injury. Nature 2005;438:1167-1171.
17. Karadottir R, Cavelier P, Bergersen LH, et al: NMDA receptors are expressed in oligodendrocytes and activated in ischaemia. Nature 2005;438:1162-1166.
18. Micu I, Jiang Q, Coderre E, et al: NMDA receptors mediate calcium accumulation in myelin during chemical ischaemia. Nature 2006;439:988-992.
19. Perez-Otano I, Ehlers MD: Homeostatic plasticity and NMDA receptor trafficking. Trends Neurosci 2005;28:229-238.
20. Simon RP, Swan JH, Griffiths T, et al: Blockade of N-methyl-D-aspartate receptors may protect against ischemic damage in the brain. Science 1984;226:850-852.
21. Volpe JJ: Neurobiology of periventricular leukomalacia in the premature infant. Pediatr Res 2001;50:553-562.
22. Fisher M: Recommendations for advancing development of acute stroke therapies: Stroke Therapy Academic Industry Roundtable 3. Stroke 2003;34:1539-1546.
23. Lees KR, Zivin JA, Ashwood T, et al: NXY-059 for acute ischemic stroke. N Engl J Med 2006;354:588-600.
24. Lipton SA: Paradigm shift in neuroprotection by NMDA receptor blockade: memantine and beyond. Nat Rev Drug Discov 2006;5:160-170.
25. Creeley C, Wozniak DF, Labruyere J, et al: Low doses of memantine disrupt memory in adult rats. J Neurosci 2006;26:3923-3932.
26. Lipton SA: NMDA receptors, glial cells and clinical medicine. Neuron 2006;50:9-11.