Effect of particle size distribution and flow property of powder blend on tablet weight variation

American Pharmaceutical Review

Volumn 8, Issue 2, 2005, Pages 73-78

  Fan, Allan ^a   Pallerla, Sam ^a   Carlson, Glenn ^a   Ladipo, Dauda ^a   Dukich, Joe ^a   Capella, Roberto ^a   Leung, Spence ^a  

^a PFIZER INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DILUENT; HYDROXYPROPYLCELLULOSE; LACTOSE; MAGNESIUM STEARATE; MICROCRYSTALLINE CELLULOSE;

DRUG FORMULATION; PARTICLE SIZE; POWDER; REVIEW; TABLET;

EID: 33749334911     PISSN: 10998012     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (12)

1. Carstensen, J.T. Advanced Pharmaceutical Solids. Marcel Dekker, Inc. New York, (2001) 309-321.
2. Amidon, G.E. Physical and mechanical property characterization of powders. In: Brittain HG (ed). Physical Characterization of Pharmaceutical Solids. Marcel Dekker, Inc. New York (1995) 281-319.
3. Teunou, E, Fitzpatrick, J.J., Synnott, E.C. Characterisation of food powder flowability. J Food Eng, 39 (1999) 31-37.
4. York, P. Powder failure testing - pharmaceutical applications. Int J Pharm, 6 (1980) 89-117.
5. Guerin, E., Techoreloff, P., Leclerc, B., Tanguy, D., Deleuil, M., Couarraze, G. Rheological characterization of pharmaceutical powders using tap testing, shear cell and mercury porosimeter. Int J Pharm, 189 (1999) 91-103.
6. Velasco Antequera, M.V., Muñoz Ruia, A., Monedero Perales, M.C., Muñoz Muñoz, N., Jiménez-Castellanos Ballesteros, M.R. Evaluation of an adequate method of estimating flowability according to powder characteristics. Int J Pharm, 103 (1994) 155-161.
7. Hiestand, E.N., Wilcox, C.J. Some measurements of friction in simple powder beds. J Pharm Sci, 57 (8) (1968) 1421-1427.
8. Mullarney, M.P., Hancock, B.C., Carlson, G.T., Ladipo, D.D., Langdon, B.A. The powder flow and compact mechanical properties of sucrose and three high-intensity sweeteners used in chewable tablets. Int J Pharm, 257 (2003) 227-236.
9. Bhattachar, S.N., Hedden, D.B., Olsofsky, A.M., Qu, X., Hsieh, W.Y., Canter, K.G. Evaluation of the vibratory feeder method for assessment of powder flow properties. Int J Pharm 269 (2004) 385-392.
10. Hancock, B.C., Vukovinsky, K.E., Brolley, B., Grimsey, I., Hedden, D., Olsofsky, A., Doherty, R.A. Development of a robust procedure for assessing powder flow using a commercial avalanche testing instrument. J Pharm Biomed Anal 35 (2204) 979-990.
11. Shangraw, R.F. Compressed tablets by direct compression. In: Lieberman HA, Lachman L, Schwartz JB (eds). Pharmaceutical Dosage Forms: Tablets (Vol. 1, 2nd ed). Marcel Dekker, Inc. New York (1989) 195-246.
12. Patel, N.K., Upadhyay, A.M., Bergum, J.S., Reier, G.E. An evaluation of microcrystalline cellulose and lactose excipients using an instrumented single station tablet press. Int J Pharm, 110 (1994) 203-210.