Anti-inflammatory and antiatherogenic effects of insulin

Insulin

Volumn 1, Issue SUPPL. 1, 2006, Pages

  Dandona, Paresh ^a   Chaudhuri, Ajay ^b  

^a UNIVERSITY AT BUFFALO   (United States)

^b MILLARD FILLMORE HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; ANGIOTENSIN RECEPTOR ANTAGONIST; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; FIBRINOLYTIC AGENT; GLUCOSE; HEPARIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INSULIN; MATRIX METALLOPROTEINASE; POTASSIUM; REACTIVE OXYGEN METABOLITE; RETEPLASE; REVIPARIN; THROMBOPLASTIN;

ACUTE HEART INFARCTION; ANTIINFLAMMATORY ACTIVITY; ARTICLE; ATHEROSCLEROSIS; CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; CLINICAL TRIAL; DIABETES MELLITUS; DRUG EFFECT; DRUG HALF LIFE; DRUG POTENTIATION; ENZYME SYNTHESIS; GLUCOSE BLOOD LEVEL; HEART MUSCLE INJURY; HUMAN; INSULIN INFUSION; MONONUCLEAR CELL; NONHUMAN; PRIORITY JOURNAL; THROMBOSIS;

EID: 33749317198     PISSN: 15570843     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1557-0843(06)80030-8     Document Type: Article

References (21)

1. Libby P., Ridker P.M., and Maseri A. Inflammation and atherosclerosis. Circulation 105 (2002) 1135-1143
2. Ridker P.M., Cushman M., Stampfer M.J., et al. Inflammation, aspirin, and the risk of cardiovascular disease in apparently healthy men. N Engl J Med 336 (1997) 973-979
3. Blackwell T.S., and Christman J.W. The role of nuclear factor-kappa B in cytokine gene regulation. Am J Respir Cell Mol Biol 17 (1997) 3-9
4. Mohanty P., Hamouda W., Garg R., et al. Glucose challenge stimulates reactive oxygen species (ROS) generation by leucocytes. J Clin Endocrinol Metab 85 (2000) 2970-2973
5. Mohanty P., Ghanim H., Hamouda W., et al. Both lipid and protein intakes stimulate increased generation of reactive oxygen species by polymorphonuclear leukocytes and mononuclear cells. Amer J Clin Nutr 75 (2002) 767-772
6. Aljada A., Ghanim H., Mohanty P., et al. Glucose intake induces an increase in activator protein 1 and early growth response 1 binding activities, in the expression of tissue factor and matrix metalloproteinose in mononuclear cells, and in plasma tissue factor and matrix metalloproteinase concentrations. Am J Clin Nutr 80 (2004) 51-57
7. Meier J.J., Deifuss S., Klamann A., et al. Plasma glucose at hospital admission and previous metabolic control determine myocardial infarct size and survival in patients with and without type 2 diabetes: The Langendreer Myocardial Infarction and Blood Glucose in Diabetic Patients Assessment (LAMBDA). Diabetes Care 28 (2005) 2551-2553
8. Mehta S.R., Yusuf S., Diaz R., et al., CREATE-ECLA Trial Group Investigators. Effect of glucose-insulin-potassium infusion on mortality in patients with acute ST-segment elevation myocardial infarction: The CREATE-ECLA randomized controlled trial. JAMA 293 (2005) 437-446
9. Aljada A., Ghanim H., Assion E., and Dandona P. Tumor necrosis factoralpha inhibits insulin-induced increase in endothelial nitric oxide synthose and reduces insulin receptor content and phosphorylation in human aortic endothelial cells. Metabolism 51 (2002) 487-491
10. Aljada A., Ghanim H., Saadeh R., and Dandona P. Insulin inhibits NFkappaB and MCP-1 expression in human aortic endothelial cells. J Clin Endocrinol Metab 86 (2001) 450-453
11. Dandona P., Aljada A., Mohanty P., et al. Insulin inhibits intranuclear nuclear factor kappaB and stimulates IkappaB in mononuclear cells in obese subjects: Evidence for an anti-inflammatory effect?. J Clin Endocrinol Metab 86 (2001) 3257-3265
12. Aljada A., Ghanim H., Mohanty P., et al. Insulin inhibits the proinflammatory transcription factor early growth response gene-1 (Egr)-1 expression in mononuclear cells (MNC) and reduces plasma tissue factor (TF) and plasminogen activator inhibitor-1 (PAI-1) concentrations. J Clin Endocrinol Metab 87 (2002) 1419-1422
13. Dandona P., Aljada A., Mohanty P., et al. Insulin suppresses plasma concentration of vascular endothelial growth factor and matrix metalloproteinase-9. Diabetes Care 26 (2003) 3310-3314
14. Malik R.A., Li C., Aziz W., et al. Elevated plasma CD 105 and vitreous VEGF levels in diabetic retinopothy. J Cell Mol Med 9 (2005) 692-697
15. Lee K.W., Lip G.Y., and Blann A.D. Plasma angiopoietin-1, angiopoietin-2, angiopoietin receptor tie-2, and vascular endothelial growth factor levels in acute coronary syndromes. Circulation 110 (2004) 2355-2360
16. Weis S., Shintani S., Weber A., et al. Src blockade stabilizes a Flk/cadherin complex, reducing edema and tissue injury following myocardial infarction. J Clin Invest 113 (2004) 885-894
17. Chaudhuri A., Janicke D., Wilson M.F., et al. Anti-inflammatory and profibrinolytic effect of insulin in acute ST-segment-elevation myocardial infarction. Circulation 109 (2004) 849-854
18. Genser N., Lechleitner P., Maier J., et al. Rebound increase of plasminogen activator inhibitor type I after cessation of thrombolytic treatment for acute myocardial infarction is independent of type of plasminogen activator used. Clin Chem 44 (1998) 209-214
19. Pisono C., Aulicino C., Vesci L., et al. Undersulfated, low-molecularweight glycol-split heparin as an antiangiogenic VEGF antagonist. Glycobiology 15 (2005) 1C-6C
20. Visser L., Zuurbier C.J., Hoek F.J., et al. Glucose, insulin and potassium applied as perioperative hyperinsulinaemic normoglycaemic clamp: Effects on inflammatory response during coronary artery surgery. Br J Anaesth 95 (2005) 448-457
21. Wang V.W., McLean M., Boyages S.C., and Cheung N.W. C-reactive protein levels following acute myocardial infarction. Diabetes Care 27 (2004) 2971-2973