Determination of phylloquinone and cholecalciferol encapsulated in granulates formed by melt extrusion

Journal of Biochemical and Biophysical Methods

Volumn 69, Issue 1-2, 2006, Pages 101-112

  Petritz, E ^a   Tritthart, T ^a,b   Wintersteiger, R ^a  

^a UNIVERSITY OF GRAZ   (Austria)

^b Mnadis Melt Extrusion Technologies   (Austria)

Author keywords

Cholecalciferol; HPLC; Phylloquinone; Solvent free granulation

Indexed keywords

CARBOHYDRATE; COLECALCIFEROL; HEXANE; PENTANOL; PHYTOMENADIONE; PHYTOMENADIONE OXIDE;

ARTICLE; CIS ISOMER; DECOMPOSITION; ENCAPSULATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RADIATION DETECTION; TRANS ISOMER; ULTRAVIOLET RADIATION;

BIOTECHNOLOGY; CAPSULES; CHOLECALCIFEROL; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG COMPOUNDING; SPECTROPHOTOMETRY, ULTRAVIOLET; STEREOISOMERISM; VITAMIN K 1;

EID: 33749257705     PISSN: 0165022X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jbbm.2006.03.007     Document Type: Article

References (30)

1. Koshihara Y., and Vitamin K. Nippon Rinsho 57 10 (1999) 2247-2253
2. 1 to bone. J Bone Miner Res 20 (2005) 283-293
3. Parrish D.B. Determination of vitamin K in foods: a review. Crit Rev Food Sci Nutr 13 4 (1998) 337-352
4. 1 2,3-epoxide in rat liver by high-performance liquid chromatography. J Chromatogr 375 1 (1986) 147-153
5. 1 2,3-epoxide in rabbit plasma by high-performance liquid chromatography. J Chromatogr 277 (1983) 292-299
6. 1), phylloquinone 2,3-epoxide, 2-chloro-phylloquinone and their geometric isomers by high-performance liquid chromatography. J Chromatogr 200 (1980) 293-299
7. 1) in humans. Am J Clin Nutr 67 6 (1998) 1226-1231
8. Szulc P., Chapuy M.C., Meunier P.J., and Delmas P.D. Serum undercarboxylated osteocalcin is a marker of the risk of hip fracture: a three year follow-up study. Bone 18 5 (1996) 487-488
9. Binkley N.C., Krueger D.C., Kawahara T.N., Engelke J.A., Chappell R.J., and Suttie J.W. A high phylloquinone intake is required to achieve maximal osteocalcin γ-carboxylation. Am J Clin Nutr 76 (2002) 1055-1060
10. Kalkwarf H.J., Khoury J.C., Bean J., and Elliot J.G. Vitamin K, bone turnover and bone mass in girls. Am J Clin Nutr 80 4 (2004) 1075-1080
11. 1 on fluoride-induced bone changes in growing rats: a histomorphometric and radiodensitometric study. Arch Oral Biol 50 10 (2005) 889-895
12. 2 with calcium supplements prevent nonvertebral fracture in elderly women with Alzheimer's disease. Bone 36 1 (2005) 61-68
13. 1) and apolipoprotein E genotype. Eur J Clin Nutr 59 1 (2005) 72-81
14. Koshihara Y., Hoshi K., Okawara R., Ishibashi H., and Yamamoto S. Vitamin K stimulates osteoblastogenesis and inhibits osteoclastogenesis in human bone marrow cell culture. J Endocrinol 176 3 (2003) 339-348
15. Ramadan M.F., and Mörsel J.T. Direct isocratic normal-phase HPLC assay of fat-soluble vitamins and β-carotene in oilseeds. Eur Food Res Technol 214 6 (2002) 521-527
16. 3 on fracture healing in a healthy rabbit model. Arch Orthop Trauma Surg 116 5 (1997) 271-274
17. 3 a metabolite of vitamin D that promotes bone repair. Am J Pathol 106 2 (1982) 171-179
18. Gorsek WF. Healthy bone formulations containing minerals and vitamins, US Pat. Appl. Publ., (2004) 2 pp.
19. 3 supplementation an the healing of the proximal humerus fracture: a randomised placebo-controlled study. Calcif Tissue Int 75 3 (2004) 183-188
20. Rizzolo A., and Polesello S. Chromatographic determination of vitamins in foods. J Chromatogr 624 1-2 (1992) 103-152
21. Arshady R. Manufacturing methodology of microcapsules. In: Arshady R. (Ed). Microspheres, microcapsules and liposomes (1999), Citus Books, London 279-321
22. Boyle S, Chang KT. Encapsulation of oleophilic substances and compositions produced thereby, US Pat., (1999) 14 pp.
23. Story MJ. Pharmaceutical formulations, US Pat., (1998) 8 pp.
24. Tritthart T. Extrusion method for the production of solid dispersions of encapsulated sugars, sugar alcohols and sugar substitutes. PCT Int Appl (2005) 65
25. 3 and multivitamin preparations. J Assoc Off Anal Chem 62 6 (1979) 1285-1291
26. Rougereau A., Guiller A., Gore J., and Person O. Determination of fat-soluble vitamins by HPLC, Recent. Dev. Food Anal. Proc Eur Conf Food Chem (1982) 33-40
27. 1 in vitamin K-deficient and coumarin anticoagulant-pretreated rats. J Pharmacol Exp Ther 209 3 (1979) 330-333
28. 1 and related compounds. J Am Chem Soc 62 10 (1940) 2866-2871
29. Knauer T.E., Siegfried C., Willingham A.K., and Matschiner J.T. Metabolism and biological activity of cis- and trans-phylloquinone in the rat. J Nutr 105 12 (1975) 1519-1524
30. 1 epoxide in human plasma with electrofluorimetric reaction detection. J Chromatogr 289 (1984) 377-385