Rational diagnosis and treatment in infertility

Best Practice and Research: Clinical Obstetrics and Gynaecology

Volumn 20, Issue 5, 2006, Pages 647-664

  De Sutter, Petra ^a  

^a GHENT UNIVERSITY HOSPITAL   (Belgium)

Author keywords

diagnosis; in vitro fertilisation; infertility; insemination; subfertility

Indexed keywords

ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; CARNITINE; CHORIONIC GONADOTROPIN; CLOMIFENE CITRATE; GLUTATHIONE; GONADORELIN AGONIST; GONADOTROPIN DERIVATIVE; METFORMIN; UBIDECARENONE;

ANOVULATION; DIAGNOSTIC PROCEDURE; ENDOMETRIOSIS; ENDOMETRIUM BIOPSY; FERTILIZATION IN VITRO; GENETIC SCREENING; HUMAN; HYSTEROSCOPY; INFERTILITY; INFERTILITY THERAPY; INSULIN RESISTANCE; INTRACYTOPLASMIC SPERM INJECTION; INTRAUTERINE INSEMINATION; LAPAROSCOPY; LOW DRUG DOSE; MALE INFERTILITY; MULTIPLE PREGNANCY; OBESITY; OVARY HYPERSTIMULATION; OVARY POLYCYSTIC DISEASE; OVULATION DETECTION; PHYSICAL EXAMINATION; POSTCOITAL TEST; PREGNANCY RATE; PRENATAL DIAGNOSIS; PRIORITY JOURNAL; PROGNOSIS; REVIEW; SEMEN ANALYSIS; SPERMATOZOON ABNORMALITY; SUBFERTILITY; TREATMENT FAILURE;

ANOVULATION; ENDOMETRIOSIS; EVIDENCE-BASED MEDICINE; FALLOPIAN TUBES; FEMALE; HUMANS; HYSTEROSCOPY; INFERTILITY, FEMALE; INFERTILITY, MALE; LAPAROSCOPY; MALE; OVULATION; PREGNANCY; PREGNANCY OUTCOME; PROGNOSIS; REPRODUCTIVE TECHNIQUES, ASSISTED; SEMEN; SPERM MOTILITY; SPERMATOZOA;

EID: 33749253366     PISSN: 15216934     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bpobgyn.2006.04.005     Document Type: Review

References (83)

1. Guzick D.S., Grefenstette I., Baffone K., et al. Infertility evaluation in fertile women: a model for assessing the efficacy of infertility testing. Human Reproduction 9 (1994) 2306-2310
2. Vroomen P.C., de Krom M.C., and Knottnerus J.A. Consistency of history taking and physical examination in patients with suspected lumbar nerve root involvement. Spine 25 (2000) 91-96
3. de Boer E.J., den Tonkelaar I., Burger C.W., et al. Validity of self-reported causes of subfertility. American Journal of Epidemiology 161 (2005) 978-986
4. Gnoth C., Godehardt D., Godehardt E., et al. Time to pregnancy: results of the German prospective study and impact on the management of infertility. Human Reproduction 18 (2003) 1959-1966
5. Eimers J.M., te Velde E.R., Gerritse R., et al. The prediction of the chance to conceive in subfertile couples. Fertility and Sterility 61 (1994) 44-52
6. Hunault C.C., Habbema J.D., Eijkemans M.J., et al. Two new prediction rules for spontaneous pregnancy leading to live birth among subfertile couples, based on the synthesis of three previous models. Human Reproduction 19 (2004) 2019-2026
7. Osmanagaoglu K., Collins J., Kolibianakis E., et al. Spontaneous pregnancies in couples who discontinued intracytoplasmic sperm injection treatment: a 5-year follow-up study. Fertility and Sterility 78 (2002) 550-556
8. Collins J.A., Burrows E.A., and Wilan A.R. The prognosis for live birth among untreated infertile couples. Fertility and Sterility 64 (1995) 22-28
9. Axmon A., and Hagmar L. Time to pregnancy and pregnancy outcome. Fertility and Sterility 84 (2005) 966-974
10. Westrom L.V. Chlamydia and its effect on reproduction. Journal of the British Fertility Society 1 (1996) 23-30
11. Thonneau P., Ducot B., and Spira A. Risk factors in men and women consulting for infertility. International Journal of Fertility and Menopausal Studies 38 (1993) 37-43
12. Suonio S., Saarikoski S., Kauhanen O., et al. Smoking does affect fecundity. European Journal of Obstetrics, Gynecology and Reproductive Biology 34 (1990) 89-95
13. Klonoff-Cohen H., Natarajan L., Marrs R., and Yee B. Effects of female and male smoking on success rates of IVF and gamete intra-Fallopian transfer. Human Reproduction 16 (2001) 1382-1390
14. Neal M.S., Hughes E.G., Holloway A.C., et al. Sidestream smoking is equally as damaging as mainstream smoking on IVF outcomes. Human Reproduction 20 (2005) 2531-2535
15. Helmerhorst F.M., Oei S.G., Bloemenkamp K.W., and Keirse M.J. Variations in fertility studies in The Netherlands. Nederlands Tijdschrift voor Geneeskunde 139 (1995) 2088-2091
16. Carlsen E., Andersen A.G., Buchreitz L., et al. Inter-observer variation in the results of the clinical andrological examination including estimation of testicular size. International Journal of Andrology 23 (2000) 248-253
17. Gat Y., Bachar G.N., Zukerman Z., et al. Physical examination may miss the diagnosis of bilateral varicocele: a comparative study of 4 diagnostic modalities. Journal of Urology 172 (2004) 1414-1417
18. Schipper R.A., Trum J.W., Messelink E.J., et al. Transrectal ultrasonography in male subfertility patients: an intra- and interobserver study. Urological Research 29 (2001) 57-59
19. Behre H.M., Kuhlage J., Gassner C., et al. Prediction of ovulation by urinary hormone measurements with the home use ClearPlan Fertility Monitor: comparison with transvaginal ultrasound scans and serum hormone measurements. Human Reproduction 15 (2000) 2478-2482
20. Krassas G.E. Thyroid disease and female reproduction. Fertility and Sterility 74 (2000) 1063-1070
21. van Zonneveld P., Koppeschaar H.P., Habbema J.D., et al. Diagnosis of subtle ovulation disorders in subfertile women with regular menstrual cycles: cost-effective clinical practice?. Gynecological Endocrinology 13 (1999) 42-47
22. Lamb E.J. Looking at the endometrial biopsy with evidence-based medicine. Fertility and Sterility 82 (2004) 1283-1285
23. Escobar-Morreale H.F., Asuncion M., Calvo R.M., et al. Receiver operating characteristic analysis of the performance of basal serum hormone profiles for the diagnosis of polycystic ovary syndrome in epidemiological studies. European Journal of Endocrinology 145 (2001) 619-624
24. Griffith C.S., and Grimes D.A. The validity of the postcoital test. American Journal of Obstetrics and Gynecology 162 (1990) 615-620
25. Oei S.G., Bloemenkamp K.W., Helmerhorst F.M., et al. Evaluation of the postcoital test for assessment of 'cervical factor' infertility. European Journal of Obstetrics, Gynecology and Reproductive Biology 64 (1996) 217-220
26. Oei S.G., Helmerhorst F.M., Bloemenkamp K.W., et al. Effectiveness of the postcoital test: randomised controlled trial. British Medical Journal 317 (1998) 502-505
27. World Health Organization. WHO Laboratory Manual for the Examination of Human Semen and Sperm-Cervical Mucus Interaction. 4th edn (1999), Cambridge University Press, Cambridge
28. Mcleod J., and Gold R.Z. The male factor in fertility and infertility. II. Spermatozoon counts in 1000 men of known fertility and in 1000 cases of infertile marriage. Journal of Urology 66 (1951) 436-448
29. Ombelet W., Wouters E., Boels L., et al. Sperm morphology assessment: diagnostic potential and comparative analysis of strict or WHO criteria in a fertile and a subfertile population. International Journal of Andrology 20 (1997) 367-372
30. Menkveld R., Wong W.Y., Lombard C.J., et al. Semen parameters, including WHO and strict criteria morphology, in a fertile and subfertile population: an effort towards standardization of in-vivo thresholds. Human Reproduction 16 (2001) 1165-1171
31. Bohring C., and Krause W. The intra- and inter-assay variation of the indirect mixed antiglobulin reaction test: is a quality control suitable?. Human Reproduction 14 (1999) 1802-1805
32. National Electronic Library for Health. The initial investigation and management of the infertile couple. Available from: (1999). http://www.nelh.nhs.uk/guidelinesdb/html/recommendations/InfertileCouple.html
33. Rowe P.J., Comhaire F.H., Hargreave T.B., and Mellows H.J. WHO Manual for the Standardized Investigation and Diagnosis of the Infertile Couple (1993), Cambridge University Press, Cambridge
34. Mol B.W., Collins J.A., Burrows E.A., et al. Comparison of hysterosalpingography and laparoscopy in predicting fertility outcome. Human Reproduction 14 (1999) 1237-1242
35. Evers J.L., Land J.A., and Mol B.W. Evidence-based medicine for diagnostic questions. Seminars in Reproductive Medicine 21 (2003) 9-15
36. Vandekerckhove P., Watson A., Lilford R., et al. Oil-soluble versus water-soluble media for assessing tubal patency with hysterosalpingography or laparoscopy in subfertile women. Cochrane Database Systematic Reviews 2 (2000) CD000092
37. Strandell A., Bourne T., Bergh C., et al. The assessment of endometrial pathology and tubal patency: a comparison between the use of ultrasonography and X-ray hysterosalpingography for the investigation of infertility patients. Ultrasound in Obstetrics and Gynecology 14 (1999) 200-204
38. Cimen G., Trak B., Elpek G., et al. The efficiency of hysterosalpingo-contrast sonography (HyCoSy) in the evaluation of tubal patency. Journal of Obstetrics and Gynaecology 19 (1999) 516-518
39. Exacoustos C., Zupi E., Carusotti C., et al. Hysterosalpingo-contrast sonography compared with hysterosalpingography and laparoscopic dye pertubation to evaluate tubal patency. Journal of the American Association of Gynecologic Laparoscopists 10 (2003) 367-372
40. Chan C.C., Ng E.H., Tang O.S., et al. Comparison of three-dimensional hysterosalpingo-contrast-sonography and diagnostic laparoscopy with chromopertubation in the assessment of tubal patency for the investigation of subfertility. Acta Obstetricia et Gynecologica Scandinavica 84 (2005) 909-913
41. Mol B.W., Dijkman B., Wertheim P., et al. The accuracy of serum chlamydial antibodies in the diagnosis of tubal pathology: a meta-analysis. Fertility and Sterility 67 (1997) 1031-1037
42. de Sa Rosa e de Silva A.C., Rosa e Silva J.C., dos Reis F.J., et al. Routine office hysteroscopy in the investigation of infertile couples before assisted reproduction. Journal of Reproductive Medicine 50 (2005) 501-506
43. de Vries L.D., Dijkhuizen F.P., Mol B.W., et al. Comparison of transvaginal sonography, saline infusion sonography, and hysteroscopy in premenopausal women with abnormal uterine bleeding. Journal of Clinical Ultrasound 28 (2000) 217-223
44. Aytoz A., Tournaye H., Camus M., et al. Is there any need for diagnostic laparoscopy in couples undergoing intracytoplasmic sperm injection for severe male-factor infertility. Journal of Assisted Reproduction and Genetics 15 (1998) 79-83
45. Lavy Y., Lev-Sagie A., Holtzer H., et al. Should laparoscopy be a mandatory component of the infertility evaluation in infertile women with normal hysterosalpingogram or suspected unilateral distal tubal pathology?. European Journal of Obstetrics, Gynecology and Reproductive Biology 114 (2004) 64-68
46. Tanahatoe S., Hompes P.G., and Lambalk C.B. Accuracy of diagnostic laparoscopy in the infertility work-up before intrauterine insemination. Fertility and Sterility 79 (2003) 361-366
47. Marcoux S., Maheux R., and Berube S. Laparoscopic surgery in infertile women with minimal or mild endometriosis. Canadian Collaborative Group on Endometriosis. New England Journal of Medicine 337 (1997) 217-222
48. Parazzini F. Ablation of lesions or no treatment in minimal-mild endometriosis in infertile women: a randomized trial. Gruppo Italiano per lo Studio dell'Endometriosi. Human Reproduction 14 (1999) 1332-1334
49. Erel C.T., and Senturk L.M. Is laparoscopy necessary before assisted reproductive technology?. Current Opinion in Obstetrics and Gynecology 17 (2005) 243-248
50. Johnson N.P., Mak W., and Sowter M.C. Surgical treatment for tubal disease in women due to undergo in vitro fertilisation. Cochrane Database Systematic Reviews 3 (2004) CD002125
51. Somigliana E., Vercellini P., Vigano P., et al. Should endometriomas be treated before IVF-ICSI cycles?. Human Reproduction Update 12 (2006) 57-64
52. Rimington M.R., Walker S.M., and Shaw R.W. The use of laparoscopic ovarian electrocautery in preventing cancellation of in-vitro fertilization treatment cycles due to risk of ovarian hyperstimulation syndrome in women with polycystic ovaries. Human Reproduction 12 (1997) 1443-1447
53. Aboulghar M.A., Mansour R.T., Serour G.I., and Al-Inany H.G. Diagnosis and management of unexplained infertility: an update. Archives of Gynecology and Obstetrics 267 (2003) 177-188
54. Abbott J., Hawe J., Hunter D., et al. Laparoscopic excision of endometriosis: a randomized, placebo-controlled trial. Fertility and Sterility 82 (2004) 878-884
55. Everaert K., Mahmoud A., Depuydt C., et al. Chronic prostatitis and male accessory gland infection - is there an impact on male infertility (diagnosis and therapy)?. Andrologia 35 (2003) 325-330
56. Nieschlag E., Hertle L., Fischedick A., et al. Update on treatment of varicocele: counselling as effective as occlusion of the vena spermatica. Human Reproduction 13 (1998) 2147-2150
57. Evers J.L., and Collins J.A. Surgery or embolisation for varicocele in subfertile men. Cochrane Database Systematic Reviews 3 (2004) CD000479
58. Sheweita S.A., Tilmisany A.M., and Al-Sawaf H. Mechanisms of male infertility: role of antioxidants. Current Drug Metabolism 6 (2005) 495-501
59. Ng C.M., Blackman M.R., Wang C., and Swerdloff R.S. The role of carnitine in the male reproductive system. Annals of the New York Academy of Science 1033 (2004) 177-188
60. Ombelet W., Deblaere K., Bosmans E., et al. Semen quality and intrauterine insemination. Reproductive Biomedicine Online 7 (2003) 485-492
61. Donnez J., Pirard C., Smets M., et al. Surgical management of endometriosis. Best Practice and Research. Clinical Obstetrics and Gynaecology 18 (2004) 329-348
62. Pritts E.A., and Taylor R.N. An evidence-based evaluation of endometriosis-associated infertility. Endocrinology and Metabolism Clinics of North America 32 (2003) 653-667
63. Kennedy S., Bergqvist A., Chapron C., et al. ESHRE guideline for the diagnosis and treatment of endometriosis. Human Reproduction 20 (2005) 2698-2704
64. Kuivasaari P., Hippelainen M., Anttila M., and Heinonen S. Effect of endometriosis on IVF/ICSI outcome: stage III/IV endometriosis worsens cumulative pregnancy and live-born rates. Human Reproduction 20 (2005) 3130-3135
65. Hull M.G.R., and Fleming C.F. Tubal surgery versus assisted reproduction: assessing their role in infertility therapy. Current Opinion in Obstetrics and Gynecology 7 (1995) 160-167
66. Benadiva C.A., Kligman I., Davis O., and Rosenwaks Z. In vitro fertilization versus tubal surgery: is pelvic reconstructive surgery obsolete?. Fertility and Sterility 64 (1995) 1051-1061
67. Watson A., Vandekerckhove P., and Lilford R. Techniques for pelvic surgery in subfertility. Cochrane Database Systematic Reviews 2 (2000) CD000221
68. Ribeiro S.C., Tormena R.A., Giribela C.G., et al. Laparoscopic tubal anastomosis. International Journal of Gynaecology and Obstetrics 84 (2004) 142-146
69. Cohlen B.J. Should we continue performing intrauterine inseminations in the year 2004?. Gynecologic and Obstetric Investigation 59 (2005) 3-13
70. Stewart J.A. Stimulated intra-uterine insemination is not a natural choice for the treatment of unexplained subfertility. Should the guidelines be changed?. Human Reproduction 18 (2003) 903-907
71. van Rumste M.M., den Hartog J.E., Dumoulin J.C., et al. Is controlled ovarian stimulation in intrauterine insemination an acceptable therapy in couples with unexplained non-conception in the perspective of multiple pregnancies?. Human Reproduction 21 (2006) 701-704
72. Pandian Z., Bhattacharya S., Vale L., and Templeton A. In vitro fertilisation for unexplained subfertility. Cochrane Database Systematic Reviews 2 (2005) CD003357
73. Bungum L., Bungum M., Humaidan P., and Andersen C.Y. A strategy for treatment of couples with unexplained infertility who failed to conceive after intrauterine insemination. Reproductive Biomedicine Online 8 (2004) 584-589
74. Orvieto R. Can we eliminate severe ovarian hyperstimulation syndrome?. Human Reproduction 20 (2005) 320-322
75. De Sutter P., Gerris J., and Dhont M. A health-economic decision-analytic model comparing double with single embryo transfer in IVF/ICSI. Human Reproduction 11 (2002) 2891-2896
76. Gerris J. Single embryo transfer and IVF/ICSI outcome: a balanced appraisal. Human Reproduction Update 10 (2004) 1-17
77. Kjellberg A.T., Carlsson P., and Bergh C. Randomized single versus double embryo transfer: obstetric and paediatric outcome and a cost-effectiveness analysis. Human Reproduction 21 (2006) 210-216
78. Elder K., and Dale B. Oocyte retrieval and embryo culture. In: Elder K., and Dale B. (Eds). In vitro Fertilization. 2nd edn (2000), Cambridge University Press, Cambridge 152-191
79. Elder K., and Dale B. Micromanipulation techniques. In: Elder K., and Dale B. (Eds). In vitro Fertilization. 2nd edn (2000), Cambridge University Press, Cambridge 228-270
80. Crosignani P.G., and Rubin B.L. Optimal use of infertility diagnostic tests and treatments. The ESHRE Capri Workshop Group. Human Reproduction 15 (2000) 723-732
81. Shah K., Sivapalan G., Gibbons N., et al. The genetic basis of infertility. Reproduction 126 (2003) 13-25
82. Hargreave T.B. Genetics and male infertility. Current Opinion in Obstetrics and Gynecology 12 (2000) 207-219
83. Griffin D.K., and Finch K.A. The genetic and cytogenetic basis of male infertility. Human Fertility (Cambridge) 8 (2005) 19-26