A new application of pre-normalized principal component analysis for improvement of image quality and clinical diagnosis in human brain PET studies-Clinical brain studies using [11C]-GR205171, [11C]-l-deuterium-deprenyl, [11C]-5-Hydroxy-l-Tryptophan, [11C]-l-DOPA and Pittsburgh Compound-B

NeuroImage

Volumn 33, Issue 2, 2006, Pages 588-598

  Razifar, Pasha ^a,b   Axelsson, Jan ^b   Schneider, Harald ^b   Långström, Bengt ^b   Bengtsson, Ewert ^a   Bergström, Mats ^c  

^a UPPSALA UNIVERSITY   (Sweden)

^b Uppsala Imanet   (Sweden)

^c UPPSALA UNIVERSITY   (Sweden)

Author keywords

Masked volume; Positron Emission Tomography; Pre normalization; Principal component analysis; Volume wise

Indexed keywords

5 HYDROXYTRYPTOPHAN C 11; LEVO BETA (3,4 DIHYDROXYPHENYL)ALANINE C 11; N [2 METHOXY 5 [5 (TRIFLUOROMETHYL) 1 TETRAZOLYL]BENZYL] N (2 PHENYLPIPERIDIN 3 YL)AMINE C 11; PITTSBURGH COMPOUND B; TRACER; UNCLASSIFIED DRUG;

ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DISCRIMINANT ANALYSIS; HUMAN; IMAGE ANALYSIS; IMAGE ENHANCEMENT; IMAGE QUALITY; NEUROANATOMY; NEUROIMAGING; POSITRON EMISSION TOMOGRAPHY; PRINCIPAL COMPONENT ANALYSIS; PRIORITY JOURNAL;

ANTIEMETICS; BRAIN; BRAIN MAPPING; CARBON RADIOISOTOPES; DEUTERIUM; HUMANS; IMAGE PROCESSING, COMPUTER-ASSISTED; LEVODOPA; PIPERIDINES; POSITRON-EMISSION TOMOGRAPHY; SELEGILINE; TETRAZOLES;

EID: 33749239594     PISSN: 10538119     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroimage.2006.05.060     Document Type: Article

References (37)

1. Bergström M., Fasth K.J., Kilpatrick G., Ward P., Cable K.M., Wipperman M.D., Sutherland D.R., and Langström B. Brain uptake and receptor binding of two [11C]labelled selective high affinity NK1-antagonists, GR203040 and GR205171-PET studies in rhesus monkey. Neuropharmacology 39 (2000) 664-670
2. Bertoldo A., Sparacino G., and Cobelli C. "Population" approach improves parameter estimation of kinetic models from dynamic PET data. IEEE Trans. Med. Imag. 23 3 (2004) 297-306
3. Cunningham V.J., and Jones T. Spectral analysis of dynamic PET studies. J. Cereb. Blood Flow Metab. 13 (1993) 15-23
4. Esbensen K., and Geladi P. Strategy of multivariate image analysis (MIA). Chemometr. Intell. Lab. Syst. 7 (1989) 67-86
5. Faulkner K., and Moores B.M. Analysis of X-ray computed tomography images using the noise power spectrum and autocorrelation function. Phys. Med. Biol. 29 (1984) 1343-1352
6. 11C]l-deprenyl in brain and peripheral organs in humans. Nucl. Med. Biol. 31 (2004) 313-319
7. Friston K.J., Frith C.D., Liddle P.F., and Frackowiak R.S.J. Functional connectivity: the principal-component analysis of large (PET) data sets. J. Cereb. Blood Flow Metab. 13 (1993) 5-14
8. Friston K.J., Poline J.-B., Holmes A.P., Frith C.D., and Frackowiak R.S.J. A multivariate analysis of PET activation studies. Hum. Brain Mapp. 4 (1996) 140-151
9. Gefvert O., Lindstrom L.H., Waters N., Waters S., Carlsson A., and Tedroff J. Different corticostriatal patterns of l-DOPA utilization in patients with untreated schizophrenia and patients treated with classical antipsychotics or clozapine. Scand J. Psychol. 44 3 (2003) 289-292
10. Gjedde A., Reith J., Dyve S., Léger G., Guttman M., Diksic M., Evans A., and Kuwabara H. Dopa decarboxylase activity of the living human brain. Proc. Natl. Acad. Sci. Neurobiol. 88 (1991) 2721-2725
11. Goadsby P.J., Hoskin K.L., and Knight Y.E. Substance P blockade with the potent and centrally acting antagonist GR205171 does not effect central trigeminal activity with superior sagittal sinus stimulation. Neuroscience 86 1 (1998) 337-343
12. 11C]-5-Hydroxyn-l-Tryptophan for positron emission tomography assessment of serotonin synthesis in human brain. J. Cereb. Blood Flow Metab. 22 (2002) 1352-1366
13. Holm S., Toft P., and Jensen M. Estimation of the noise contributions from blank, transmission and emission scans in PET. IEEE Trans. Nucl. Sci. 43 (1996) 2285-2291 (Part 1)
14. Klunk W.E., Engler H., Nordberg A., Wang Y., Blomqvist B., Holt D.P., Bergström M., Savitcheva I., Huang G.F., Estrada S., Ausén B., Debnath M.L., Barletta J., Price J.C., Sandell J., Lopresti B.J., Wall A., Koivisto P., Antoni G., Mathis C.A., and Långström B. Imaging brain amyloid in Alzheimer's disease with Pittsburgh compound-B. Ann. Neurol. 55 (2004) 306-319
15. 18F-FDG in focal epilepsy. Acta Neurol. Scand. 103 (2001) 360-366
16. 11C]Tryptophan and its in vivo-formed radiolabeled metabolites in brain tissue using high performance liquid chromatography: a study supporting radiotracer kinetics obtained with positron emission tomography. Nucl. Med. Biol. 24 (1997) 733-738
17. Logan J. Graphical analysis of PET data applied to reversible and irreversible tracers. Nucl. Med. Biol. 27 (2000) 661-670
18. Logan J., Fowler J.S., Volkow N.D., Wang G.J., MacGregor R.R., and Shea C. Reproducibility of repeated measures of deuterium substituted [11C]l-deprenyl ([11C]l-deprenyl-D2) binding in the human brain. Nucl. Med. Biol. 27 (2000) 43-49
19. Mathis C.A., Wang Y., Holt D.P., Huang G.-F., Debnath M.L., and Klunk W.E. Synthesis and evaluation of 11C-labeled 6-substituted 2-aryl benzothiazoles as amyloid imaging agents. J. Med. Chem. 46 (2003) 2740-2754
20. Nichols N.F., Cimini M.G., Haas J.V., Staton B.A., Tedroff J., and Svensson K.A. PNU-96391A (OSU6162) antagonizes the development of behavioral sensitization induced by dopamine agonists in a rat model for Parkinson's disease. Neuropharmacology 43 5 (2002) 817-824
21. Pakrasi S., and O'Brien J.T. Emission tomography in dementia. Nucl. Med. Commun. 26 3 (2005) 189-196
22. Patlak C.S., Blasberg R.G., and Fenstermacher J.D. Graphical evaluation of blood-to-brain transfer constants from multiple-time uptake data. J. Cereb. Blood Flow Metab. 3 (1983) 1-7
23. Pedersen F., Bengtsson E., and Jonsson D. A numerically derived method for preprocessing of noisy data before applying principal component analysis. Proc. 8th Scand. Conf. Image Anal., Norwegian International Association for Pattern Recognition (IAPR) (1993) 981-988
24. Pedersen F., Bergström M., Bengtsson E., and Maripuu E. Principal component analysis of dynamic PET and gamma camera images: a methodology to visualize the signals in the presence of large noise. IEEE Nucl. Sci. Symp. Med. Imaging Conf. Rec. 3 (1993) 1734-1738
25. Pedersen F., Bergström M., Bengtsson E., and Långström B. Principal component analysis of dynamic positron emission tomography images. Eur. J. Nucl. Med. l 21 (1994) 1285-1292
26. Pedersen F., Bengtsson E., and Nordin B. An extended strategy for exploratory multivariate image analysis including noise considerations. J. Chemom. 9 (1995) 389-409
27. Razifar P., Lubberink M., Schneider H., Långstrom B., Bengtsson E., and Bergström M. Non-isotropic noise correlation in PET data reconstructed by FBP but not by OSEM demonstrated using auto-correlation function. BMC Med. Imaging 5 (2005) 1
28. Razifar P., Sandström M., Schneider H., Långstrom B., Maripuu E., Bengtsson E., and Bergström M. Noise correlation in PET, CT, SPECT and PET/CT data evaluated using autocorrelation function: a phantom study on data, reconstructed using FBP and OSEM. BMC Med. Imaging 5 (2005) 3
29. Razifar, P., Muhammed, H.H., Schneider, H., Långström, B., Bengtsson, E., Bergström, M., submitted for publication. Performance of PCA and ICA with respect to signal extraction from noisy PET data-a study on computer simulated images.
30. Razifar, P., Blomquist, G., Engler, H., Ringheim, A., Schneider, H., Långström, B., Bengtsson, E., and Bergström, M., submitted for publication. Principal component analysis for improved image quality in PET studies of amyloid deposits in Alzheimer's Disease.
31. Šámal M., Kárný M., Benali H., Backfrieder W., Todd-Pokropek A., and Bergmann H. Experimental comparison of data transformation procedures for analysis of principal components. Phys. Med. Biol. 44 (1999) 2821-2834
32. 11C] 5-hydroxy-l-tryptophan uptake and decarboxylation in carcinoid tumors by specific positioning labeling in positron emission tomography. Nucl. Med. Biol. 27 (2000) 33-41
33. Sundin A., Eriksson B., Bergström M., Långström B., Öberg K., and Örlefors H. PET in the diagnosis of neuroendocrine tumors. Acad. Sci. 1014 (2004) 246-257
34. Thireou T., Strauss L., Kontaxakis G., Pavlopoulos S., and Santos A. Principal component analysis in dynamic PET. Conf. Rec. (2001) 241-243 (CASEIB)
35. Thireou T., Strauss L.G., Dimitrakopoulou-Strauss A., Kontaxakis G., Pavlopoulos S., and Santos A. Performance evaluation of principal component analysis in dynamic FDG-PET studies of recurrent colorectal cancer. Comput. Med. Imaging Graph. 27 1 (2003) 43-51
36. Tsui, B.M.W., 1977. Effects of the recorder system on spatial resolution and noise in the nuclear medicine," PhD thesis, The University of Chicago, USA.
37. Van Ameringen M., Mancini C., Szechtman H., Nahmias C., Oakman J.M., Hall G.B., Pipe B., and Farvolden P. A PET provocation study of generalized social phobia. Psychiatry Res. 15 132 (2004) 13-18