DLPC and SAMe prevent α1(I) collagen mRNA up-regulation in human hepatic stellate cells, whether caused by leptin or menadione

Biochemical and Biophysical Research Communications

Volumn 350, Issue 1, 2006, Pages 50-55

  Cao, Qi ^a   Mak, Ki M ^a   Lieber, Charles S ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

1(I) collagen mRNA; Dilinoleoylphosphatidylcholine; ERK1 2; H2O2; Hepatic stellate cells; Leptin; Menadione; p38; Reduced glutathione; S Adenosylmethionine

Indexed keywords

COLLAGEN DERIVATIVE; COLLAGEN TYPE 1 ALPHA1; DILINOLEOYLPHOSPHATIDYLCHOLINE; GLUTATHIONE; GLYCEROPHOSPHOLIPID; HYDROGEN PEROXIDE; LEPTIN; MENADIONE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; S ADENOSYLMETHIONINE; TISSUE INHIBITOR OF METALLOPROTEINASE 1; UNCLASSIFIED DRUG; 1,2 DILINOLENOYLPHOSPHATIDYLCHOLINE; 1,2-DILINOLENOYLPHOSPHATIDYLCHOLINE; CATALASE; COLLAGEN TYPE 1; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLCHOLINE; PROTEIN KINASE INHIBITOR;

ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; LIVER CELL; LIVER FIBROSIS; PRIORITY JOURNAL; PROTEIN DEPLETION; STELLATE CELL; UPREGULATION; CELL LINE; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; METABOLISM; PHOSPHORYLATION;

CATALASE; CELL LINE; COLLAGEN TYPE I; GLUTATHIONE; HEPATOCYTES; HUMANS; HYDROGEN PEROXIDE; LEPTIN; MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHATIDYLCHOLINES; PHOSPHORYLATION; PROTEIN KINASE INHIBITORS; RNA, MESSENGER; S-ADENOSYLMETHIONINE; UP-REGULATION; VITAMIN K 3;

EID: 33749234968     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2006.08.174     Document Type: Article

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