Prognostic significance of Cyclin A in epidermoid anal cancer

Oncology Reports

Volumn 16, Issue 3, 2006, Pages 443-449

  Nilsson, Per J ^a,b   Lenander, Claes ^a   Rubio, Carlos ^b   Auer, Gert ^b   Ljungqvist, Olle ^a,b   Glimelius, Bengt ^b,c  

^a ERSTA HOSPITAL   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^c UPPSALA UNIVERSITY   (Sweden)

Author keywords

Anus neoplasm; Cyclin A; p21; p53; Prognosis; Radiotherapy

Indexed keywords

ANTINEOPLASTIC AGENT; CD31 ANTIGEN; CDKN1A PROTEIN, HUMAN; CYCLIN A; CYCLIN DEPENDENT KINASE INHIBITOR 1A; PROTEIN P53; TUMOR MARKER;

ADULT; AGED; ANUS TUMOR; ARTICLE; COHORT ANALYSIS; DISEASE FREE SURVIVAL; FEMALE; HUMAN; MALE; METABOLISM; MIDDLE AGED; MORTALITY; PROSPECTIVE STUDY; SQUAMOUS CELL CARCINOMA; SURVIVAL RATE; TREATMENT OUTCOME;

ADULT; AGED; AGED, 80 AND OVER; ANTIGENS, CD31; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; ANUS NEOPLASMS; CARCINOMA, SQUAMOUS CELL; COHORT STUDIES; CYCLIN A; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DISEASE-FREE SURVIVAL; FEMALE; HUMANS; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; SURVIVAL RATE; TREATMENT OUTCOME; TUMOR MARKERS, BIOLOGICAL; TUMOR SUPPRESSOR PROTEIN P53;

EID: 33749170155     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.16.3.443     Document Type: Article

References (29)

1. Fenger C: Prognostic factors in anal carcinoma. Pathology 34: 573-578, 2002.
2. Nilsson PJ, Svensson C, Goldman S and Glimelius B: Salvage abdominoperineal resection in anal epidermoid cancer. Br J Surg 89: 1425-1429, 2002.
3. West CML, McKay MJ, Hölscher T, et al: Molecular markers predicting radiotherapy response: report and recommendations from an international Atomic Energy Agency technical meeting. Int J Radiat Oncol Biol Phys 62: 1264-1273, 2005. (Pubitemid 40982043)
4. Vogelstein B, Lane D and Levine AJ: Surfing the p53 network. Nature 408: 307-310, 2000.
5. Waf1/Cip1/Sdi1: association with cell senescence and tumour-promoting activities of stromal fibroblasts. Cancer Lett 179: 1-14, 2002.
6. Sherr CJ: Cancer cell cycles. Science 274: 1672-1677, 1996.
7. Pagano M, Pepperkok R, Verde F, Ansorge W and Draetta G: Cyclin A is required at two points in the human cell cycle. EMBO J 11: 961-971, 1992.
8. Vermeulen PB, Gasparini G, Fox SB, et al: Quantification of angiogenesis in solid human tumours: an international consensus on the methodology and criteria of evaluation. Eur J Cancer 14: 2474-2484, 1996.
9. Nilsson PJ, Svensson C, Goldman S, Ljungqvist O and Glimelius B: Epidermoid anal cancer: A review of a population-based series of 308 consecutive patients treated according to prospective protocols. Int J Radiat Oncol Biol Phys 61: 92-102, 2005. (Pubitemid 40039110)
10. Wong CS, Tsao MS, Sharma W, Chapman WB, Pintile M and Cummings BJ: Prognostic role of p53 expression in epidermoid carcinoma of the anal canal. Int J Radiat Oncol Biol Phys 45: 309-314, 1999. (Pubitemid 29408543)
11. Bonin SR, Pajak TF, Russell AH, Coia LR, Paris KJ, Flam MS and Sauter ER: Overexpression of p53 protein and outcome of patients treated with chemoradiation for carcinoma of the anal canal. Cancer 85:1226-1233, 1999. (Pubitemid 29125074)
12. Allal AS, Waelchli L and Bründler M-A: Prognostic value of apoptosis-regulating protein expression in anal squamous cell carcinoma. Clin Cancer Res 9: 6489-6496, 2003. (Pubitemid 38031838)
13. Allal AS, Gervaz P and Bründler M-A: Cyclin D1, cyclin E and p21 have no apparent prognostic value in anal carcinomas treated by radiotherapy with or without chemotherapy. Br J Cancer 91: 1239-1244, 2004. (Pubitemid 39424781)
14. Saarilahti K, Kajanti M, Kouri M, Aaltonen LM, Franssila K and Joensuu H: Cyclin A and Ki-67 expression as predictors for locoregional recurrence and outcome in laryngeal cancer patients treated with surgery and postoperative radiotherapy. Int J Radiat Oncol Biol Phys 57: 986-995, 2003. (Pubitemid 37324116)
15. Holm R, Skovlund E, Skomedal H, Flørenes VA and Tanum G: Reduced expression of p21 WAF1 is an indicator of malignant behaviour in anal carcinomas. Histopathology 39: 43-49, 2001. (Pubitemid 32848273)
16. Grabenbauer GG, Matzel KE, Schneider IH, Meyer M, Wittekind C, Matsche B, Hohenberger W, et al: Sphincter preservation with chemoradiation in anal canal carcinoma: Abdominoperineal resection in selected cases? Dis Colon Rectum 1: 441-450, 1998. (Pubitemid 28169669)
17. Allal AS, Alonso-Pentzke L and Remadi S: Apparent lack of prognostic value of MIB-1 index in anal carcinomas treated with radiotherapy. Br J Cancer 77: 1333-1336, 1998. (Pubitemid 28140625)
18. Wong CS, Tsang RW, Cummings BJ, Fyles AW, Couture J, Brierley JD and Pintilie M: Proliferation parameters in epidermoid carcinomas of the anal canal. Radiother Oncol 56: 349-353, 2000.
19. Van de Putte G, Kristensen GB, Lie AK, Baekelandt M and Holm R: Cyclins and proliferation markers in early squamous cell carcinoma. Gynecol Oncol 92: 40-46, 2004. (Pubitemid 38147369)
20. Raybaud-Diogène H, Fortin A, Morency R, Roy J, Monteil RA and Tetu B: Markers of radioresistance in squamous cell carcinoma of the head and neck: a clinicopathologic and immunohistichemical study. J Clin Oncol 15: 1030-1038, 1997. (Pubitemid 27106287)
21. Kropveld A, Slootweg PJ, Blankenstein MA, Terhaard CA and Hordijk GJ: Ki-67 and p53 in T2 laryngeal cancer. Laryngoscope 108: 1548-1552, 1998. (Pubitemid 28465256)
22. Raybaud H, Fortin A, Bairati I, Morency R, Monteil RA and Tetu B: Nuclear DNA content, an adjunct to p53 and Ki-67 as a marker of resistance to radiation therapy in oral cavity and pharyngeal squamous cell carcinoma. Int J Oral Maxillofac Surg 29: 36-41, 2000.
23. Couture C, Raybaud-Diogène H, Têtu B, Bairati I, Murry D, Allard J and Fortin A: p53 and Ki-67 as markers of radio-resistance in head and neck carcinoma. Cancer 94: 713-722, 2002. (Pubitemid 34132300)
24. Kennedy AS, Raleigh JA, Perez GM, Calkins DP, Thrall DE, Novotny DB and Varia MA: Proliferation and hypoxia in human squamous cell carcinoma of the cervix: first report of combined immunohistochemical assays. Int J Radiat Oncol Biol Phys 37: 897-905, 1997. (Pubitemid 27181324)
25. Hoskin PJ, Sibtain A, Daley FM, Saunders MI and Wilson GD: The immunohistochemical assessment of hypoxia, vascularity and proliferation in bladder carcinoma. Radiother Oncol 72: 159-168, 2004. (Pubitemid 39024591)
26. Cuddihy AR and Bristow RG: The p53 family and radiation sensitivity: Yes or no? Cancer Metastasis Rev 23: 237-257, 2004. (Pubitemid 38881809)
27. Lowe SW, Ruley HE, Jacks T and Housman DE: p53-dependent apoptosis modulates the cytotoxicity of anticancer agents. Cell 74: 957-967, 1993. (Pubitemid 23289454)
28. Koike M, Fujita F, Komori K, Katoh F, Sugimoto T, Matsuda M and Fujita M: Dependence of chemotherapy response on p53 mutation status in a panel of human cancer lines maintained in nude mice. Cancer Sci 95: 541-546, 2004. (Pubitemid 38832705)
29. Ghouti L, Houvenaeghel G, Moutardier V, Giovannini M, Magnin V, Lelong B, Bardou V-J, et al: Salvage abdominoperineal resection after failure of conservative treatment in anal epidermoid cancer. Dis Colon Rectum 48: 16-22, 2005. (Pubitemid 40895652)