Nosocomial spread of OXA-58-positive carbapenem-resistant Acinetobacter baumannii isolates in a paediatric hospital in Greece

Clinical Microbiology and Infection

Volumn 12, Issue 11, 2006, Pages 1138-1141

  Poirel, L ^a   Lebessi, E ^b   Heritier C ^a   Patsoura, A ^b   Foustoukou, M ^b   Nordmann, Patrice ^a  

^a BICÊTRE HOSPITAL   (France)

^b Aglaia Kyriakou Children's Hospital   (Greece)

Author keywords

Acinetobacter baumannii; Carbapenems; Greece; OXA 58; Oxacillinase; Resistance

Indexed keywords

AMINOGLYCOSIDE; BACTERIAL DNA; BACTERIAL ENZYME; BETA LACTAM ANTIBIOTIC; CARBAPENEM; COLISTIN; IMIPENEM; MEROPENEM; QUINOLINE DERIVED ANTIINFECTIVE AGENT; RIFAMPICIN;

ACINETOBACTER BAUMANNII; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL GENE; BACTERIAL TRANSMISSION; BACTERIUM ISOLATE; DNA SEQUENCE; GREECE; HOSPITAL INFECTION; HUMAN; NONHUMAN; PEDIATRIC HOSPITAL; PLASMID; PRIORITY JOURNAL;

ACINETOBACTER BAUMANNII;

EID: 33749058907     PISSN: 1198743X     EISSN: 14690691     Source Type: Journal    
DOI: 10.1111/j.1469-0691.2006.01537.x     Document Type: Article

References (22)

1. Van Looveren M, Goossens H and the ARPAC Steering Group. Antimicrobial resistance of Acinetobacter spp. in Europe. Clin Microbiol Infect 2004; 10: 684-704.
2. Poirel L, Nordmann P. Carbapenem resistance in Acinetobacter baumannii: mechanisms and epidemiology. Clin Microbiol Infect 2006; 12: 826-837.
3. Héritier C, Poirel L, Fournier PE, Claverie JM, Raoult D, Nordmann P. Characterization of the naturally-occurring oxacillinase of Acinetobacter baumannii. Antimicrob Agents Chemother 2005; 49: 4174-4179.
4. Brown S, Amyes SG. The sequences of seven class D β-lactamases isolated from carbapenem-resistant Acinetobacter baumannii from four continents. Clin Microbiol Infect 2005; 11: 326-329.
5. Bou G, Cervero G, Dominguez MA, Quereda C, Martinez-Beltran J. Characterization of a nosocomial outbreak caused by a multiresistant Acinetobacter baumannii strain with a carbapenem-hydrolyzing enzyme: High-level carbapenem resistance in A. baumannii is not due solely to the presence of β-lactamases. J Clin Microbiol 2000; 38: 3299-3305.
6. Dalla-Costa LB, Coelho JM, Souza HA et al. Outbreak of carbapenem-resistant Acinetobacter baumannii producing the OXA-23 enzyme in Curitiba, Brazil. J Clin Microbiol 2003; 41: 3403-3406.
7. Jeon BC, Jeong SH, Bae IK et al. Investigation of a nosocomial outbreak of imipenem-resistant Acinetobacter baumannii producing the OXA-23 β-lactamase in Korea. J Clin Microbiol 2005; 43: 2241-2245.
8. Turton JF, Kaufmann ME, Glover J et al. Detection and typing of integrons in epidemic strains of Acinetobacter baumannii found in the United Kingdom. J Clin Microbiol 2005; 43: 3074-3082.
9. Naas T, Levy M, Hirschauer C, Marchandin H, Nordmann P. Outbreak of carbapenem-resistant Acinetobacter baumannii producing the carbapenemase OXA-23 in a tertiary care hospital of Papeete, French Polynesia. J Clin Microbiol 2005; 43: 4826-4829.
10. Lopez-Otsoa F, Gallego L, Towner KJ et al. Endemic carbapenem resistance associated with OXA-40 carbapenemase among Acinetobacter baumannii isolates from a hospital in northern Spain. J Clin Microbiol 2002; 40: 4741-4743.
11. Da Silva GJ, Quinteira S, Bertolo E et al. Long-term dissemination of an OXA-40 carbapenemase-producing Acinetobacter baumannii clone in the Iberian Peninsula. J Antimicrob Chemother 2004; 54: 255-258.
12. Héritier C, Dubouix A, Poirel L, Marty N, Nordmann P. A nosocomial outbreak of Acinetobacter baumannii isolates expressing the carbapenem-hydrolysing oxacillinase OXA-58. J Antimicrob Chemother 2005; 55: 115-118.
13. Marqué S, Poirel L, Héritier C et al. Regional occurrence of plasmid-mediated carbapenem-hydrolyzing oxacillinase OXA-58 in Acinetobacter spp. in Europe. J Clin Microbiol 2005; 43: 4885-4888.
14. Peleg AY, Franklin C, Walters LJ, Bell JM, Spelman DW. OXA-58 and IMP-4 carbapenem-hydrolyzing β-lactamases in an Acinetobacter junii blood culture isolate from Australia. Antimicrob Agents Chemother 2006; 50: 399-400.
15. Coelho J, Woodford N, Afzal-Shah M, Livermore D. Occurrence of OXA-58-like carbapenemases in Acinetobacter spp. collected over 10 years in three continents. Antimicrob Agents Chemother 2006; 50: 756-758.
16. Héritier C, Poirel L, Lambert T, Nordmann P. Contribution of acquired carbapenem-hydrolyzing oxacillinases to carbapenem resistance in Acinetobacter baumannii. Antimicrob Agents Chemother 2005; 49: 3198-3202.
17. OXA-58 in Acinetobacter baumannii. Antimicrob Agents Chemother 2006; 50: 1442-1448.
18. Clinical and Laboratory Standards Institute. Performance standards for antimicrobial susceptibility testing, 15th informational supplement. M100-S15. Wayne, PA: Clinical and Laboratory Standards Institute, 2005.
19. Poirel L, Menuteau O, Agoli N, Cattoen C, Nordmann P. Outbreak of extended-spectrum β-lactamase VEB-1-producing isolates of Acinetobacter baumannii in a French hospital. J Clin Microbiol 2003; 41: 3542-3547.
20. Kieser T. Factors affecting the isolation of CCC DNA from Streptomyces lividans and Escherichia coli. Plasmid 1984; 12: 19-36.
21. Poirel L, Marqué S, Héritier C, Segonds C, Chabanon G, Nordmann P. OXA-58, a novel class D β-lactamase involved in resistance to carbapenems in Acinetobacter baumannii. Antimicrob Agents Chemother 2005; 49: 202-208.
22. Pournaras S, Markogiannakis A, Ikonomidis A et al. Outbreak of multiple clones of imipenem-resistant Acinetobacter baumannii isolates expressing OXA-58 carbapenemase in an intensive care unit. J Antimicrob Chemother 2006; 57: 557-561.