Emerging antiviral drugs from medicinal mushrooms

International Journal of Medicinal Mushrooms

Volumn 8, Issue 2, 2006, Pages 101-114

  Pirano, Frank F ^a  

^a UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

Author keywords

Antiviral mushrooms; High molecular weight carbohydrates and proteins; Low molecular weight compounds; Medicinal mushrooms; Rozites caperatus

Indexed keywords

ACICLOVIR; ANTIVIRUS AGENT; APPLANOIDIC ACID; CARBOHYDRATE DERIVATIVE; GANCICLOVIR; GANODERMADIOL; GLYCOPROTEIN; ILLUDIN S; INTERFERON; LUCIDADIOL; NEVIRAPINE; OSELTAMIVIR; PEPTIDE DERIVATIVE; PLECONARIL; PROTEIN; PROTEIN PULP; RIBAVIRIN; RIMANTADINE; SAQUINAVIR; SESQUITERPENE DERIVATIVE; TRITERPENE DERIVATIVE; UBIQUITIN; UNCLASSIFIED DRUG; VIDARABINE; ZANAMIVIR; ZIDOVUDINE;

ADENOVIRUS; ANTIVIRAL ACTIVITY; COXSACKIE VIRUS A; COXSACKIE VIRUS B; CYTOMEGALOVIRUS; DRUG CYTOTOXICITY; DRUG ISOLATION; DRUG MECHANISM; ECHO VIRUS; HERPES SIMPLEX VIRUS 1; HERPES SIMPLEX VIRUS 2; HUMAN; IC 50; INFLUENZA VIRUS A; MOLECULAR WEIGHT; MUSHROOM; NONHUMAN; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; REVIEW; ROUS SARCOMA ONCOVIRUS; ROZITES CAPERATUS; STRUCTURE ACTIVITY RELATION; VARICELLA ZOSTER VIRUS; VIRUS INHIBITION; VIRUS ISOLATION; VIRUS REPLICATION;

BASIDIOMYCOTA; CORTINARIUS CAPERATUS;

EID: 33749032416     PISSN: 15219437     EISSN: None     Source Type: Journal    
DOI: 10.1615/IntJMedMushr.v8.i2.20     Document Type: Review

References (50)

1. Arora A., Magee L., Peck J., and Singer J. 2001. Antiviral therapeutics for the pediatric population. J Pediater Emerg Care, 17, 369-380.
2. Awadh N. A., Mothana R. A., Lesnau A., Pilgrm H., and Lindequist U. 2003. Antiviral activity of Inonotus hispidus. Fitoterapia, 74, 483-485.
3. Bauer D. J. 1985. A history of the discovery and clinical application of antiviral drugs. J Br Med Bull, 41, 309-14.
4. Bernardshaw S., Johnson E., and Hetland G. 2005. An extract of the mushroom Agaricus blazei Murrill administered orally protects against systemic Streptococcus pneumoniae infection in mice. Scand J Immunol, 62, 393-398.
5. Brandt C. and Piraino F. 2000. Mushroom antivirals. Recent Res Dev Antimicrob Agents Chemother, 4, 11-26.
6. Cadwell K. and Coscoy L. 2005. Ubiquitination on nonlysine residues by a viral E3 ubiquitin ligase. Science, 309, 127-130.
7. Castilla J., Del Romero J., Hernando V., Marincovich B., Garcia S., and Rodriguez C. J. 2005. Effectiveness of highly active antiretroviral therapy in reducing heterosexual transmission of HIV. J AIDS, 40, 96-101.
8. Centers for Disease Control and Prevention. Sexually transmitted diseases. General information. http://www.cdc.gov/nchstp/dstd/disease-info.htm.
9. Chakrabarty A. and Beutner K. 2004. Therapy of other viral infections: herpes to hepatitis. Dermatol Ther, 17, 465-490.
10. Conaway R., Brower C. S., and Conaway J. W. 2002. Emerging roles of ubiquitin in transcription regulation. Science, 296, 1254-1258.
11. Didukh M. Ya., Wasser S. P., and Nevo E. 2003. Medicinal value of species of the family Agaricaceae Cohn (higher Basidiomycetes): current state of knowledge and future perspectives. Int J Med Mushr, 5, 133-152.
12. Didukh M. Ya., Wasser S. P., and Nevo E. 2004. Impact of the family Agaricaceae on nutrition and medicine. Gantner Verlag, Ruggell.
13. Everett R.D. and Murray J. 2005. ND 10 components relocate to sites associated with Herpes Simplex Virus 'Type 1 nucleoprotein complexes during virus infection. J Virology, 79(8), 5078-5089.
14. Fishman D. and Lipsitch M. 2002. Projection of the future dimensions and costs of the genital herpes simplex type 2 epidemic in the United States. Sex TransDis, 29, 608-619.
15. Galasso G. J, Merigan T. C., and Buchanan. 1984. Antiviral Agents and Viral Diseases of Man. New York, Raven Press.
16. Goldwater P. 1984. Antiviral drugs today. N Z Med J, 97, 852-854.
17. Hagglund R. and Roizman B. 2004. Role of ICPO in the strategy of conquest of the host cell by Herpes simplex virus 1. Virology, 78, 2169-2178.
18. Kanokmedhaku S., Soytong K., Kongsaeree P., and Suksamram A. 2003. A bioactive triterpenoid and vulpinic acid derivatives from the mushroom Scleroderma citrinum. Planta Med, 69, 568-571.
19. Kawaguchi Y., Van Sant C., and Roizman B. 1998. Eukaryotic elongation factor 1(sigma mark) is hyperphosphorylated by the protein kinase encoded by the Ul13 gene of Herpes Simplex Virus 1. J Virology, 72(3), 1731-1736.
20. Kleymann G. 2003. Novel agents and strategies to treat herpes simplex virus infections. Expert Opin Invest Drugs, 12, 165-183.
21. Kostolansky F. and Fislova T. 2005. The factors of virulence of influenza A virus. Acta Virol, 49, 147-157.
22. Krawdczyk E., Kuczak M., Kobus M., Banka D., and Daniewski W. 2003. Antiviral activity of N-benzoylphenylisoserinates of Lactarius sesquiterpenoid alcohols in vitro. Planta Med, 69, 552-554.
23. Lehmann, V., Huang, A., Ibanez-Calero, S., and Rinehard, K. 2003. Illudin S, the sole antiviral compound in mature fruiting bodies of Omphalotus illudens. J Nat Prod, 66, 1257-1258.
24. Marks J. 2002. Ubiquitin lives up to its name. Science, 297, 1792-1794.
25. McMorris T., Lira R., Gantzel P., Kelner M. and Dawe R. J. 2000. Sesquiterpenes from the basidiomycete Omphalotus illudens. J Nat Prod, 63, 1557-1559.
26. Maul G. 1998. Nuclear domain 10, the site of DNA virus transcription and replication. BioEssays , 20(8), 660-667.
27. Mentel F., Meinsen D., Pilgrim H. Herrmann B., and Lindequist U. 1994. In vitro antiviral effect of extracts of Kuehneromyces mutabilis on Influenza virus. Pharmazie, 49, 859-860.
28. Microbiology @ Leicester: Virology: Antivirals, http://www.micro.msb.le. ac.uk/3035Antivirals.html.
29. Migliaccio G., Tomassini J. E., Carroll S. S., Tomei L., Altamura S., Bhat B., et al. 2003. Characterization of resistance to non-obligate chain-terminating ribonucleoside analogs that inhibit hepatitis C virus replication in vitro. J Biol Chem, 278, 49164-49170.
30. Mizuno T. 1999. The extraction and development of antitumoractive polysaccharides from medicinal mushrooms in Japan. Int J Med Mushr, 1, 9-29.
31. Mothana R., Awadh N. Jansen R., Wegner U., Mentel R., and Lindequest U. 2003. Antiviral lanostanoid triterpenes from the fungus Ganoderma pfeifferi. Fitoterapia, 74, 177-180.
32. Nyindo M. 2005. Complementary factors contributing to the rapid spread of HIV-1 in sub-Saharan Africa. East Afr Med J, 82, 40-46.
33. Parent D. 2005. Genital Herpes. Rev Med Brux, 26, S360-S363.
34. Piraino F. 1967. The mechanism of genetic resistance of chick embryo cells to infection by Rous sarcoma virus-Bryan strain (BS-RSV). Virology, 32, 700-707.
35. Piraino F. and Brandt C. 1999. Isolation and partial characterization of an antiviral, RC183, from the edible mushroom Rozites caperata. Antiviral Res, 43, 67-78.
36. Putterman D., Pepinsky R. B., and Vogt V. M. 1990. Ubiquitin in avian leucosis virus particles. Virology, 176, 633-637.
37. Rodriguez M. E., Llop A., Capo V., Louri V., Resik S., Rojas L., Soto Y., Mune M., Rodriguez I., and Hengge U. 2005. Human immunodeficiency virus and other sexually transmitted diseases in Cuban women. Clin Microbiol Infect, 1, 764-767.
38. Rubin H. 2003. Complementary approaches to understanding the role of proteases and their natural inhibitors in neoplastic development: retrospect and prospect. Carcinogenesis, 24, 803-816.
39. Sibrack D. D., Gutman L. T., Wilfert C. M., McLaren C., St. Clair M. T., Keller P. M., and Barry D. W. 1982. Pathogenicity of acyclovir-resistant herpes simplex virus type 1 from an immunodeficient child. J Infect Dis, 146, 673-682.
40. Sorimachi K., Ikehara Y., Maezato G., Inafuku, K., Okubo A., and Yamazaki S. 2001. Inhibition by Agaricus blazei Murill fractions of cytopathic effect induced by Western equine encephalitis (WEE) virus on Vero cells in vitro. Biosci Biotechnol Biochem, 65, 1645-1647.
41. Stamets P. 2005. Mycelium Running. How Mushrooms Can Help Save the World. Ten Speed Press, Berkeley.
42. Steinberg D. 2001. Virus budding linked to ubiquitin system. The Scientist, Jan, 22, 16-17.
43. Tapper M. 2005. Herpesviruses in the highly active antiretroviral therapy. Clinician, 23, 1-16.
44. Voyles B. 1993. The Biology of Viruses. Mosby Press, St. Louis.
45. Wang H. X. and Ng R. B. 2000. Isolation of a novel ubiquitin-like protein from Pleurotus osteatus mushroom with anti-human immunodeficiency virus, translation-inhibitory, and ribonuclease activities. Biochem Biophys Res Comm, 276, 587-593.
46. Wasser S. P. 2002. Medicinal mushrooms as a source of antitumor and Immunomodulating polysaccharides. Appl Microbiol Biotechnol, 60, 258-274.
47. Wasser, S. P. and Weis A. L. 1999. Therapeutic effects of substances occurring in higher Basidiomycetes mushrooms: A modern perspective. Crit Rev Immunol, 19, 65-96.
48. Wasser S. P. and Didukh M. Ya. 2005. Mushroom polysaccharides in human health care. In: Biodiversity of Fungi. Their Role in Human Life. pp. 289-328. Deshmukh S. K. and Rai M. K., eds., Science Publishers, Inc Enfield, (NH), USA.
49. Yamamoto N. and Urade M. 2005. Pathogenic significance of alpha-N-acetylgalactosaminidase activity found in the hemagglutinin of influenza virus. Microbes Infect, 7, 674-681.
50. Yang H., Qi X., Sabogal A., Miller M., Xiong S., and Delaney W. E. 2005. Cross-resistance testing of next generation nucleoside and nucleotide analogs against lamivudine-resistant HBV. Antiviral Ther, 10, 625-633.