Common variatioins in the IL4R gene affect splicing and influence natural expression of the soluble isoform

Human Mutation

Volumn 27, Issue 10, 2006, Pages 990-998

  Bergin, Ann Marie ^a,d   Balder, Barbro ^a   Kishore, Shivendra ^b   Swärd, Kajsa ^a   Hahn Zoric, Mirjana ^a   Löwhagen, Olle ^a   Hanson, Lars Å ^a   Padyukov, Leonid ^a,c  

^a SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

^b UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^c KAROLINSKA INSTITUTE   (Sweden)

^d UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

Alternative splicing; Asthma; IL4R; Minigene assay; SNP; SRp20

Indexed keywords

GENOMIC DNA; INTERLEUKIN 4 RECEPTOR; MESSENGER RNA; ISOPROTEIN; NERVE PROTEIN; RNA BINDING PROTEIN; SFRS3 PROTEIN, HUMAN; YT521 PROTEIN, HUMAN;

ADOLESCENT; ADULT; ALLERGIC ASTHMA; ALTERNATIVE RNA SPLICING; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; EXON; FEMALE; GENE; GENE FREQUENCY; HAPLOTYPE; HUMAN; HUMAN CELL; IL4R GENE; MAJOR CLINICAL STUDY; MALE; NUCLEOTIDE SEQUENCE; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; AGED; ASTHMA; BINDING SITE; CELL LINE; CHEMISTRY; COMPARATIVE STUDY; GENE EXPRESSION; GENETICS; IMMUNOPRECIPITATION; METABOLISM; METHODOLOGY; MIDDLE AGED; MOLECULAR GENETICS; PROTEIN BINDING; RNA SPLICING; SOLUBILITY;

ADOLESCENT; ADULT; AGED; ASTHMA; BASE SEQUENCE; BINDING SITES; CELL LINE; FEMALE; GENE EXPRESSION; HUMANS; IMMUNOPRECIPITATION; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; NERVE TISSUE PROTEINS; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEIN BINDING; PROTEIN ISOFORMS; RECEPTORS, INTERLEUKIN-4; RNA SPLICING; RNA, MESSENGER; RNA-BINDING PROTEINS; SOLUBILITY;

EID: 33749019475     PISSN: 10597794     EISSN: None     Source Type: Journal    
DOI: 10.1002/humu.20364     Document Type: Article

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