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Volumn 6, Issue 5, 2006, Pages 355-357

The pleomorphic pathology of inherited Parkinson's disease: Lessons from LRRK2

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SYNUCLEIN; ARGININE; CYSTEINE; DOPAMINE; GENE PRODUCT; GLYCINE; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; ISOLEUCINE; LEUCINE RICH REPEAT KINASE 2; NEUROFILAMENT PROTEIN; PARKIN; SERINE; TAU PROTEIN; THREONINE; TYROSINE; UBIQUITIN; UNCLASSIFIED DRUG;

EID: 33749011424     PISSN: 15284042     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11910-996-0013-z     Document Type: Note
Times cited : (14)

References (20)
  • 2
    • 8844233579 scopus 로고    scopus 로고
    • Mutations in LRRK2 cause autosomal-dominant Parkinsonism with pleomorphic pathology
    • Zimprich A, Biskup S, Leitner P, et al.: Mutations in LRRK2 cause autosomal-dominant Parkinsonism with pleomorphic pathology. Neuron 2004, 44:601-607.
    • (2004) Neuron , vol.44 , pp. 601-607
    • Zimprich, A.1    Biskup, S.2    Leitner, P.3
  • 3
    • 8844266996 scopus 로고    scopus 로고
    • Cloning of the gene containing mutations that cause PARKS-linked Parkinson's disease
    • Paisan-Ruiz C, Jain S, Evans EW, et al.: Cloning of the gene containing mutations that cause PARKS-linked Parkinson's disease. Neuron 2004, 44:595-600.
    • (2004) Neuron , vol.44 , pp. 595-600
    • Paisan-Ruiz, C.1    Jain, S.2    Evans, E.W.3
  • 5
    • 28344457936 scopus 로고    scopus 로고
    • Lrrk2 pathogenic substitutions in Parkinson's disease
    • Mata IF, Kachergus JM, Taylor JP, et al.: Lrrk2 pathogenic substitutions in Parkinson's disease. Neurogenetics 2005, 6:171-177.
    • (2005) Neurogenetics , vol.6 , pp. 171-177
    • Mata, I.F.1    Kachergus, J.M.2    Taylor, J.P.3
  • 6
    • 33644822969 scopus 로고    scopus 로고
    • Type and frequency of mutations in the LRRK2 gene in familial and sporadic Parkinson's disease
    • Berg D, Schweitzer K, Leitner P, et al.: Type and frequency of mutations in the LRRK2 gene in familial and sporadic Parkinson's disease. Brain 2005, 128:3000-3011.
    • (2005) Brain , vol.128 , pp. 3000-3011
    • Berg, D.1    Schweitzer, K.2    Leitner, P.3
  • 7
    • 28544441181 scopus 로고    scopus 로고
    • Mutations in the gene LRRK2 encoding dardarin (PARKS) cause familial Parkinson's disease: Clinical, pathological, olfactory and functional imaging and genetic data
    • Khan NL, Jain S, Lynch JM, et al.: Mutations in the gene LRRK2 encoding dardarin (PARKS) cause familial Parkinson's disease: clinical, pathological, olfactory and functional imaging and genetic data. Brain 2005, 128:2786-2796.
    • (2005) Brain , vol.128 , pp. 2786-2796
    • Khan, N.L.1    Jain, S.2    Lynch, J.M.3
  • 8
    • 33645139675 scopus 로고    scopus 로고
    • Comprehensive analysis of the LRRK2 gene in sixty families with Parkinson's disease
    • Di Fonzo A, Tassorelli C, De Mari M, et al.: Comprehensive analysis of the LRRK2 gene in sixty families with Parkinson's disease. Eur J Hum Genet 2006, 14:322-331.
    • (2006) Eur J Hum Genet , vol.14 , pp. 322-331
    • Di Fonzo, A.1    Tassorelli, C.2    De Mari, M.3
  • 9
    • 31344432937 scopus 로고    scopus 로고
    • LRRK2 G2019S as a cause of Parkinson's disease in North African Arabs
    • Lesage S, Durr A, Tazir M, et al.: LRRK2 G2019S as a cause of Parkinson's disease in North African Arabs. N Engl J Med 2006, 354:422-423.
    • (2006) N Engl J Med , vol.354 , pp. 422-423
    • Lesage, S.1    Durr, A.2    Tazir, M.3
  • 10
    • 31344439221 scopus 로고    scopus 로고
    • LRRK2 G2019S as a cause of Parkinson's disease in Ashkenazi Jews
    • Ozelius LJ, Senthil G, Saunders-Pullman R, et al.: LRRK2 G2019S as a cause of Parkinson's disease in Ashkenazi Jews. N Engl J Med 2006, 354:424-425.
    • (2006) N Engl J Med , vol.354 , pp. 424-425
    • Ozelius, L.J.1    Senthil, G.2    Saunders-Pullman, R.3
  • 11
    • 28544446980 scopus 로고    scopus 로고
    • G2019S dardarin substitution is a common cause of Parkinson's disease in a Portuguese cohort
    • Bras JM, Guerreiro RJ, Ribeiro MH, et al.: G2019S dardarin substitution is a common cause of Parkinson's disease in a Portuguese cohort. Mov Disord 2005, 20:1653-1655.
    • (2005) Mov Disord , vol.20 , pp. 1653-1655
    • Bras, J.M.1    Guerreiro, R.J.2    Ribeiro, M.H.3
  • 12
    • 33644929033 scopus 로고    scopus 로고
    • LRRK2 mutations in Spanish patients with Parkinson disease: Frequency, clinical features, and incomplete penetrance
    • Gaig C, Ezquerra M, Marti MJ, et al.: LRRK2 mutations in Spanish patients with Parkinson disease: frequency, clinical features, and incomplete penetrance. Arch Neurol 2006, 63:377-382.
    • (2006) Arch Neurol , vol.63 , pp. 377-382
    • Gaig, C.1    Ezquerra, M.2    Marti, M.J.3
  • 13
    • 33645160640 scopus 로고    scopus 로고
    • The G6055A (G2019S) mutation in LRRK2 is frequent in both early and late onset Parkinson's disease and originates from a common ancestor
    • Goldwurm S, Di Fonzo A, Simons EJ, et al.: The G6055A (G2019S) mutation in LRRK2 is frequent in both early and late onset Parkinson's disease and originates from a common ancestor. J Med Genet 2005, 42:e65.
    • (2005) J Med Genet , vol.42
    • Goldwurm, S.1    Di Fonzo, A.2    Simons, E.J.3
  • 14
    • 0036196860 scopus 로고    scopus 로고
    • A new locus for Parkinson's disease (PARKS) maps to chromosome 12p11.2 q13.1
    • Funayama M, Hasegawa K, Kowa H, et al.: A new locus for Parkinson's disease (PARKS) maps to chromosome 12p11.2 q13.1. Ann Neurol 2002, 51:296-301.
    • (2002) Ann Neurol , vol.51 , pp. 296-301
    • Funayama, M.1    Hasegawa, K.2    Kowa, H.3
  • 15
    • 0031460466 scopus 로고    scopus 로고
    • German-Canadian family (Family A) with parkinsonism, amyotrophy, and dementia - Longitudinal observations
    • Wszolek ZK, Vieregge P, Uitti RJ, et al.: German-Canadian family (Family A) with parkinsonism, amyotrophy, and dementia - longitudinal observations. Parkinsonism Relat Disord 1997, 3:125-139.
    • (1997) Parkinsonism Relat Disord , vol.3 , pp. 125-139
    • Wszolek, Z.K.1    Vieregge, P.2    Uitti, R.J.3
  • 16
    • 2342605968 scopus 로고    scopus 로고
    • Autosomal dominant parkinsonism associated with variable synuclein and tau pathology
    • Wszolek ZK, Pfeiffer RF, Tsuboi Y, et al.: Autosomal dominant parkinsonism associated with variable synuclein and tau pathology. Neurology 2004, 62:1619-1622.
    • (2004) Neurology , vol.62 , pp. 1619-1622
    • Wszolek, Z.K.1    Pfeiffer, R.F.2    Tsuboi, Y.3
  • 17
    • 19944432921 scopus 로고    scopus 로고
    • A common LRRK2 mutation in idiopathic Parkinson's disease
    • Gilks WP, Abou-Sleiman PM, Gandhi S, et al.: A common LRRK2 mutation in idiopathic Parkinson's disease. Lancet 2005, 365:415-416.
    • (2005) Lancet , vol.365 , pp. 415-416
    • Gilks, W.P.1    Abou-Sleiman, P.M.2    Gandhi, S.3
  • 18
    • 32044466285 scopus 로고    scopus 로고
    • Lrrk2 and Lewy body disease
    • Ross OA, Toft M, Whittle AJ, et al.: Lrrk2 and Lewy body disease. Ann Neurol 2006, 59:388-393.
    • (2006) Ann Neurol , vol.59 , pp. 388-393
    • Ross, O.A.1    Toft, M.2    Whittle, A.J.3
  • 19
    • 32044432395 scopus 로고    scopus 로고
    • Biochemical and pathological characterization of Lrrk2
    • Giasson BI, Covy JP, Bonini NM, et al.: Biochemical and pathological characterization of Lrrk2. Ann Neurol 2006, 59:315-322.
    • (2006) Ann Neurol , vol.59 , pp. 315-322
    • Giasson, B.I.1    Covy, J.P.2    Bonini, N.M.3
  • 20
    • 33746267531 scopus 로고    scopus 로고
    • Kinase activity is required for the toxic effects of mutant LRRK2/dardarin
    • In press
    • Greggio E, Jain S, Kingsbury A, et al.: Kinase activity is required for the toxic effects of mutant LRRK2/dardarin. Neurobiol Dis 2006, In press.
    • (2006) Neurobiol Dis
    • Greggio, E.1    Jain, S.2    Kingsbury, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.