-
1
-
-
20744435383
-
Molecular pathophysiology of Parkinson's disease
-
Moore DJ, West AB, Dawson VL, Dawson TM: Molecular pathophysiology of Parkinson's disease. Annu Rev Neurosci 2005, 28:57-87.
-
(2005)
Annu Rev Neurosci
, vol.28
, pp. 57-87
-
-
Moore, D.J.1
West, A.B.2
Dawson, V.L.3
Dawson, T.M.4
-
2
-
-
8844233579
-
Mutations in LRRK2 cause autosomal-dominant Parkinsonism with pleomorphic pathology
-
Zimprich A, Biskup S, Leitner P, et al.: Mutations in LRRK2 cause autosomal-dominant Parkinsonism with pleomorphic pathology. Neuron 2004, 44:601-607.
-
(2004)
Neuron
, vol.44
, pp. 601-607
-
-
Zimprich, A.1
Biskup, S.2
Leitner, P.3
-
3
-
-
8844266996
-
Cloning of the gene containing mutations that cause PARKS-linked Parkinson's disease
-
Paisan-Ruiz C, Jain S, Evans EW, et al.: Cloning of the gene containing mutations that cause PARKS-linked Parkinson's disease. Neuron 2004, 44:595-600.
-
(2004)
Neuron
, vol.44
, pp. 595-600
-
-
Paisan-Ruiz, C.1
Jain, S.2
Evans, E.W.3
-
5
-
-
28344457936
-
Lrrk2 pathogenic substitutions in Parkinson's disease
-
Mata IF, Kachergus JM, Taylor JP, et al.: Lrrk2 pathogenic substitutions in Parkinson's disease. Neurogenetics 2005, 6:171-177.
-
(2005)
Neurogenetics
, vol.6
, pp. 171-177
-
-
Mata, I.F.1
Kachergus, J.M.2
Taylor, J.P.3
-
6
-
-
33644822969
-
Type and frequency of mutations in the LRRK2 gene in familial and sporadic Parkinson's disease
-
Berg D, Schweitzer K, Leitner P, et al.: Type and frequency of mutations in the LRRK2 gene in familial and sporadic Parkinson's disease. Brain 2005, 128:3000-3011.
-
(2005)
Brain
, vol.128
, pp. 3000-3011
-
-
Berg, D.1
Schweitzer, K.2
Leitner, P.3
-
7
-
-
28544441181
-
Mutations in the gene LRRK2 encoding dardarin (PARKS) cause familial Parkinson's disease: Clinical, pathological, olfactory and functional imaging and genetic data
-
Khan NL, Jain S, Lynch JM, et al.: Mutations in the gene LRRK2 encoding dardarin (PARKS) cause familial Parkinson's disease: clinical, pathological, olfactory and functional imaging and genetic data. Brain 2005, 128:2786-2796.
-
(2005)
Brain
, vol.128
, pp. 2786-2796
-
-
Khan, N.L.1
Jain, S.2
Lynch, J.M.3
-
8
-
-
33645139675
-
Comprehensive analysis of the LRRK2 gene in sixty families with Parkinson's disease
-
Di Fonzo A, Tassorelli C, De Mari M, et al.: Comprehensive analysis of the LRRK2 gene in sixty families with Parkinson's disease. Eur J Hum Genet 2006, 14:322-331.
-
(2006)
Eur J Hum Genet
, vol.14
, pp. 322-331
-
-
Di Fonzo, A.1
Tassorelli, C.2
De Mari, M.3
-
9
-
-
31344432937
-
LRRK2 G2019S as a cause of Parkinson's disease in North African Arabs
-
Lesage S, Durr A, Tazir M, et al.: LRRK2 G2019S as a cause of Parkinson's disease in North African Arabs. N Engl J Med 2006, 354:422-423.
-
(2006)
N Engl J Med
, vol.354
, pp. 422-423
-
-
Lesage, S.1
Durr, A.2
Tazir, M.3
-
10
-
-
31344439221
-
LRRK2 G2019S as a cause of Parkinson's disease in Ashkenazi Jews
-
Ozelius LJ, Senthil G, Saunders-Pullman R, et al.: LRRK2 G2019S as a cause of Parkinson's disease in Ashkenazi Jews. N Engl J Med 2006, 354:424-425.
-
(2006)
N Engl J Med
, vol.354
, pp. 424-425
-
-
Ozelius, L.J.1
Senthil, G.2
Saunders-Pullman, R.3
-
11
-
-
28544446980
-
G2019S dardarin substitution is a common cause of Parkinson's disease in a Portuguese cohort
-
Bras JM, Guerreiro RJ, Ribeiro MH, et al.: G2019S dardarin substitution is a common cause of Parkinson's disease in a Portuguese cohort. Mov Disord 2005, 20:1653-1655.
-
(2005)
Mov Disord
, vol.20
, pp. 1653-1655
-
-
Bras, J.M.1
Guerreiro, R.J.2
Ribeiro, M.H.3
-
12
-
-
33644929033
-
LRRK2 mutations in Spanish patients with Parkinson disease: Frequency, clinical features, and incomplete penetrance
-
Gaig C, Ezquerra M, Marti MJ, et al.: LRRK2 mutations in Spanish patients with Parkinson disease: frequency, clinical features, and incomplete penetrance. Arch Neurol 2006, 63:377-382.
-
(2006)
Arch Neurol
, vol.63
, pp. 377-382
-
-
Gaig, C.1
Ezquerra, M.2
Marti, M.J.3
-
13
-
-
33645160640
-
The G6055A (G2019S) mutation in LRRK2 is frequent in both early and late onset Parkinson's disease and originates from a common ancestor
-
Goldwurm S, Di Fonzo A, Simons EJ, et al.: The G6055A (G2019S) mutation in LRRK2 is frequent in both early and late onset Parkinson's disease and originates from a common ancestor. J Med Genet 2005, 42:e65.
-
(2005)
J Med Genet
, vol.42
-
-
Goldwurm, S.1
Di Fonzo, A.2
Simons, E.J.3
-
14
-
-
0036196860
-
A new locus for Parkinson's disease (PARKS) maps to chromosome 12p11.2 q13.1
-
Funayama M, Hasegawa K, Kowa H, et al.: A new locus for Parkinson's disease (PARKS) maps to chromosome 12p11.2 q13.1. Ann Neurol 2002, 51:296-301.
-
(2002)
Ann Neurol
, vol.51
, pp. 296-301
-
-
Funayama, M.1
Hasegawa, K.2
Kowa, H.3
-
15
-
-
0031460466
-
German-Canadian family (Family A) with parkinsonism, amyotrophy, and dementia - Longitudinal observations
-
Wszolek ZK, Vieregge P, Uitti RJ, et al.: German-Canadian family (Family A) with parkinsonism, amyotrophy, and dementia - longitudinal observations. Parkinsonism Relat Disord 1997, 3:125-139.
-
(1997)
Parkinsonism Relat Disord
, vol.3
, pp. 125-139
-
-
Wszolek, Z.K.1
Vieregge, P.2
Uitti, R.J.3
-
16
-
-
2342605968
-
Autosomal dominant parkinsonism associated with variable synuclein and tau pathology
-
Wszolek ZK, Pfeiffer RF, Tsuboi Y, et al.: Autosomal dominant parkinsonism associated with variable synuclein and tau pathology. Neurology 2004, 62:1619-1622.
-
(2004)
Neurology
, vol.62
, pp. 1619-1622
-
-
Wszolek, Z.K.1
Pfeiffer, R.F.2
Tsuboi, Y.3
-
17
-
-
19944432921
-
A common LRRK2 mutation in idiopathic Parkinson's disease
-
Gilks WP, Abou-Sleiman PM, Gandhi S, et al.: A common LRRK2 mutation in idiopathic Parkinson's disease. Lancet 2005, 365:415-416.
-
(2005)
Lancet
, vol.365
, pp. 415-416
-
-
Gilks, W.P.1
Abou-Sleiman, P.M.2
Gandhi, S.3
-
19
-
-
32044432395
-
Biochemical and pathological characterization of Lrrk2
-
Giasson BI, Covy JP, Bonini NM, et al.: Biochemical and pathological characterization of Lrrk2. Ann Neurol 2006, 59:315-322.
-
(2006)
Ann Neurol
, vol.59
, pp. 315-322
-
-
Giasson, B.I.1
Covy, J.P.2
Bonini, N.M.3
-
20
-
-
33746267531
-
Kinase activity is required for the toxic effects of mutant LRRK2/dardarin
-
In press
-
Greggio E, Jain S, Kingsbury A, et al.: Kinase activity is required for the toxic effects of mutant LRRK2/dardarin. Neurobiol Dis 2006, In press.
-
(2006)
Neurobiol Dis
-
-
Greggio, E.1
Jain, S.2
Kingsbury, A.3
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