l-Cysteine supplementation protects the erythrocyte glucose-6-phosphate dehydrogenase activity from reduction induced by forced training

Clinical Biochemistry

Volumn 39, Issue 10, 2006, Pages 1002-1006

  Schulpis, Kleopatra H ^a   Reclos, George J ^b   Parthimos, Theodore ^c   Parthimos, Nickolaos ^c   Gavriilidis, Andreas ^d   Tsakiris, Stylianos ^c  

^a AGHIA SOPHIA CHILDREN S HOSPITAL   (Greece)

^b R and D Diagnostics   (Greece)

^c UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

^d UNIVERSITY OF ATHENS   (Greece)

Author keywords

Cysteine; Exercise; Free radicals; G6PD; Oxidation

Indexed keywords

ANTIOXIDANT; CYSTEINE; GLUCOSE 6 PHOSPHATE DEHYDROGENASE;

ADULT; ARTICLE; BASKETBALL; BLOOD SAMPLING; DRUG EFFECT; ENZYME ACTIVITY; ERYTHROCYTE; HUMAN; HUMAN EXPERIMENT; MALE; PRIORITY JOURNAL; SUPPLEMENTATION; TRAINING;

ADOLESCENT; CYSTEINE; DIETARY SUPPLEMENTS; ERYTHROCYTES; EXERCISE; GLUCOSEPHOSPHATE DEHYDROGENASE; HUMANS; MALE;

EID: 33748978427     PISSN: 00099120     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.clinbiochem.2006.06.006     Document Type: Article

References (33)

1. Meloni T., Forteleoni G., and Meloni G.F. Marked decline of favism after neonatal glucose-6-phosphate dehydrogenase screening and health education: the northern Sardinian experience. Acta Haematol. 87 (1992) 29-31
2. Sampaio C., Reclos G.J., Galloti P., Mack F.N., and Pass K. Haemoglobin normalization leads to correct classification of samples derived from wrong blood spots. 5th Meeting of the International Society for Neonatal Screening. Genova, Italy. June 26-29 (2002)
3. Kaplan M., Beutler E., Vreman H.J., Hammerman C., Levy-Lahad E., Renbaum P., et al. Neonatal hyperbilirubinemia in glucose-6-phosphate dehydrogenase-deficient heterozygotes. Pediatrics 104 (1999) 68-74
4. Kirsch M., and De Groot H. NAD(P)H, a directly operating antioxidant?. FASEB J. 15 (2001) 1569-1574
5. Carmagnol F., Sinet P.M., and Jerome H. Selenium-dependent and non-selenium-dependent glutathione peroxidases in human tissue extracts. Biochim. Biophys. Acta 759 23 (1983) 49-57
6. Anderson B.B., Carandina G., Lucci M., Perry G.M., and Vullo C. Red-cell GSH regeneration and glutathione reductase activity in G6PD variants in the Ferrara area. Br. J. Haematol. 67 (1987) 459-466
7. Johnson R.M., Ravindranath Y., el-Alfy M., and Goyette Jr. G. Oxidant damage to erythrocyte membrane in glucose-6-phosphate dehydrogenase deficiency: correlation with in vivo reduced glutathione concentration and membrane protein oxidation. Blood 83 15 (1994) 1117-1123
8. Ashton T., Young I.S., Peters J.R., Jones E., Jackson S.K., Davies B., et al. Electron spin resonance spectroscopy, exercise, and oxidative stress: an ascorbic acid intervention study. J. Appl. Physiol. 87 (1999) 2032-2036
9. Alsip H.M., Hagerman A.E., Fullerton B.K., Ambrose J., Rice R.E., and Wiley R.L. Generation of reactive oxygen species after exhaustive aerobic and isometric exercise. Med. Sci. Sports Exerc. 32 (2000) 1576-1581
10. Cooper C.E., Vollard N.B., Chouette T., and Wilson M.T. Exercise, free radicals and oxidative stress. Biochem. Soc. Trans. 30 (2002) 280-285
11. Atmaca G. Antioxidant effects of sulfur-containing amino acids. Yonsei Med. J. 45 31 (2004) 776-788
12. Aliciguzel Y., and Aslan M. N-Acetyl cysteine, l-cysteine, and beta-mercaptoethanol augment selenium-glutathione peroxidase activity in glucose-6-phosphate dehydrogenase-deficient human erythrocytes. Clin. Exp. Med. 4 (2004) 50-55
13. Lohnman T.G., Roche A.F., and Martorell R. Anthropometric standardization reference manual (1988), Human Kinetics, Champaign, IL 380-394
14. Apostolidis N., Nassis G.P., Bolatoglou T., and Geladas N.D. Physiological and technical characteristics of elite young basketball players. J. Sports Med. Phys. Fitness 44 (2004) 157-163
15. Murakami M., and Webb M. A morphological and biochemical study of the effects of l-cysteine on the renal uptake and nephrotoxicity of cadmium. Br. J. Exp. Pathol. 62 (1981) 115-130
16. Miller N.J., Rice-Evans C., Davies M.J., Copinathan V., and Milner A. A novel method for measuring antioxidant capacity and its application to monitoring the antioxidant status in premature neonates. Clin. Sci. (Lond) 84 (1993) 407-412
17. Reclos G.J., Hatzidakis C.J., and Schulpis K.H. Glucose-6-phosphate dehydrogenase deficiency neonatal screening: preliminary evidence that a high percentage of partially deficient female neonates are missed during routine screening. J. Med. Screen 7 (2000) 46-51
18. Battistuzzi G., D'Urso M., Toniolo D., Persico G.M., and Luzzatto L. Tissue-specific levels of human glucose-6-phosphate dehydrogenase correlate with methylation of specific sites at the 3' end of the gene. Proc. Natl. Acad. Sci. U.S.A. 82 (1985) 1465-1469
19. Kletzien R.F., Harris P.K., and Foellmi L.A. Glucose-6-phosphate dehydrogenase: a "housekeeping" enzyme subject to tissue-specific regulation by hormones, nutrients, and oxidant stress. FASEB J. 8 (1994) 174-181
20. Luzzatto L., and Mehta A. Glucose-6-phosphate dehydrogenase deficiency. In: Scriver C.R., Beaudet A.L., Sly W.S., and Valle D. (Eds). The metabolic and molecular bases of inherited disease (1995), McGraw-Hill, New York 3367-3398
21. Liese A.M., Siddiqi M.Q., Siegel J.H., Deitch E.A., and Spolarics Z. Attenuated monocyte IL-10 production in glucose-6-phosphate dehydrogenase-deficient trauma patients. Shock 18 (2002) 18-23
22. Solaris Z., Side M., Siegel J.H., Garcia Z.C., Stein D.S., On H., et al. Increased incidence of sepsis and altered monocyte functions in severely injured type A-glucose-6-phosphate dehydrogenase-deficient African American trauma patients. Crit. Care Med. 29 (2001) 728-736
23. Dillard C.J., Litov R.E., Savin W.M., Dumelin E.E., and Tappel A.L. Effects of exercise, vitamin E, and ozone on pulmonary function and lipid peroxidation. J. Appl. Physiol. 45 (1978) 927-932
24. Yaki K. Lipid peroxides and related radicals in clinical medicine. In: Armistrong D. (Ed). Free radicals in diagnostic medicine (1999), Plenum Press, New York 1-14
25. Balakrishnan S.D., and Anuradha C.V. Exercise depletion of antioxidants and antioxidant manipulation. Cell Biochem. Funct. 16 (1998) 269-275
26. Rokitzki L., Logemann E., Sagredos A.N., Murphy M., Wetzel-Roth W., and Keul J. Lipid peroxidation and antioxidative vitamins under extreme endurance stress. Acta Physiol. Scand. 151 (1994) 149-158
27. Carageorgiou H., Tzotzes V., Pantos C., Mourouzis C., Zarros A., and Tsakiris S. In vivo and in vitro effects of cadmium on adult rat brain total antioxidant status, acetylcholinesterase, (Na+, K+)-ATPase and Mg2+-ATPase activities: protection by l-cysteine. Basic Clin. Pharmacol. Toxicol. 94 (2004) 112-118
28. Mariotti F., Simbelie K.L., Makarios-Lahham L., Huneau J.F., Laplaize B., Tome D., et al. Acute ingestion of dietary proteins improves post-exercise liver glutathione in rats in a dose-dependent relationship with their cysteine content. J. Nutr. 134 (2004) 128-131
29. Kim Y.G., Kim S.K., Kwon J.W., Park O.J., Kim S.G., Kim Y.C., et al. Effects of cysteine on amino acid concentrations and transsulfuration enzyme activities in rat liver with protein-calorie malnutrition. Life Sci. 72 (2003) 1171-1181
30. Packer L. Oxidants, antioxidant nutrients and the athlete. J. Sport Sci. 15 (1997) 353-363
31. Paglia D.E., and Valentine W.N. Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase. J. Lab. Clin. Med. 70 (1967) 158-169
32. Kondo T. Impaired glutathione metabolism in hemolytic anemia. Rinsho Byori 38 (1990) 355-359
33. Kinnaert E., Duez P., Morandini R., Dubois J., Van Houtte P., and Ghanem G. Cysteine but not glutathione modulates the radiosensitivity of human melanoma cells by affecting both survival and DNA damage. Pigm. Cell Res. 17 (2004) 275-280