Treatment with oxcarbazepine during pregnancy

Neurologist

Volumn 12, Issue 5, 2006, Pages 249-254

  Eisenschenk, Stephen ^a  

^a UNIVERSITY OF FLORIDA   (United States)

Author keywords

Complex partial seizures; Epilepsy; Oxcarbazepine; Pregnancy

Indexed keywords

ANTIDEPRESSANT AGENT; FOLIC ACID; GABAPENTIN; ORAL CONTRACEPTIVE AGENT; OXCARBAZEPINE; PHENYTOIN; PSYCHOTROPIC AGENT;

ABSENCE OF SIDE EFFECTS; ADULT; ARTICLE; ARTIFICIAL MILK; ATAXIA; BREAST FEEDING; CASE REPORT; COMPLEX PARTIAL SEIZURE; DEPRESSION; DIZZINESS; FEMALE; GRAND MAL EPILEPSY; HUMAN; MONOTHERAPY; PREGNANCY; PREGNANCY COMPLICATION; PRIORITY JOURNAL; TERATOGENICITY; TREATMENT DURATION; TREATMENT OUTCOME;

ADULT; ANTICONVULSANTS; CARBAMAZEPINE; EPILEPSY, COMPLEX PARTIAL; FEMALE; HUMANS; PREGNANCY; PREGNANCY COMPLICATIONS;

EID: 33748966320     PISSN: 10747931     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.nrl.0000215743.02301.17     Document Type: Article

References (25)

1. Hauser WA, Annegers JF, Kurland LT. Incidence of epilepsy and unprovoked seizures in Rochester, Minnesota: 1935-1984. Epilepsia. 1993;34:453-468.
2. Hauser WA, Annegers JF, Rocca WA. Descriptive epidemiology of epilepsy: contributions of population-based studies from Rochester, Minnesota. Mayo Clin Proc. 1996;71:576-586.
3. Crawford P, Appleton R, Betts T, et al. Best practice guidelines for the management of women with epilepsy: the Women with Epilepsy Guidelines Development Group. Seizure. 1999;8:201-217.
4. Matalon S, Schechtman S, Goldzweig G, et al. The teratogenic effect of carbamazepine: a meta-analysis of 1255 exposures. Reprod Toxicol. 2002;16:9-17.
5. Samren EB, van Duijn CM, Christiaens GC, et al. Antiepileptic drug regimens and major congenital abnormalities in the offspring. Ann Neurol. 1999;46:739-746.
6. Pennell PB. Antiepileptic drug pharmacokinetics during pregnancy and lactation. Neurology. 2003;61:S35-S42.
7. Kaaja E, Kaaja R, Hiilesmaa V. Major malformations in offspring of women with epilepsy. Neurology. 2003;60:575-579.
8. Lindhout D. Pharmacogenetics and drug interactions: role in antiepileptic-drug-induced teratogenesis. Neurology. 1992;42:43-47.
9. Lindhout D, Omtzigt JG, Cornel MC. Spectrum of neural-tube defects in 34 infants prenatally exposed to antiepileptic drugs. Neurology. 1992;42:111-118.
10. Kalis MM, Huff NA. Oxcarbazepine, an antiepileptic agent. Clin Ther. 2001;23:680-700.
11. Montouris G. Safety of the newer antiepileptic drug oxcarbazepine during pregnancy. Curr Med Res Opin. 2005;21:693-701.
12. Meischenguiser R, D'Giano CH, Ferraro SM. Oxcarbazepine in pregnancy: clinical experience in Argentina. Epilepsy Behav. 2004;5:163-167.
13. Sabers A, Dam M, Rogvi-Hansen B, et al. Epilepsy and pregnancy: lamotrigine as main drug used. Acta Neurol Scand. 2004;109:9-13.
14. Tennis P, Eldridge RR. Preliminary results on pregnancy outcomes in women using lamotrigine. Epilepsia. 2002;43:1161-1167.
15. Yerby MS. Pregnancy and epilepsy. Epilepsia. 1991;32:S51-S59.
16. McAuley JW, Anderson GD. Treatment of epilepsy in women of reproductive age: pharmacokinetic considerations. Clin Pharmacokinet. 2002;41:559-579.
17. Pack AM, Olarte LS, Morrell MJ, et al. Bone mineral density in an outpatient population receiving enzyme-inducing antiepileptic drugs. Epilepsy Behav. 2003;4:169-174.
18. Artama M, Auvinen A, Isojarvi JI. Pregnancy outcomes in women with epilepsy taking oxcarbazepine (Trileptal): findings from a Finnish National Epilepsy cohort. Epilepsia. 2004;45:130-131.
19. Lassiter A, Mamie M-M, Cid-Rufaza J, et al. Pregnancy outcomes with oxcarbazepine (Trileptal) therapy: a review of Novartis safety database. Epilepsia. 2004;45:130.
20. Fonager K, Larsen H, Pedersen L, et al. Birth outcomes in women exposed to anticonvulsant drugs. Acta Neurol Scand. 2000;101:289-294.
21. Hvas CL, Henriksen TB, Ostergaard JR, et al. Epilepsy and pregnancy: effect of antiepileptic drugs and lifestyle on birthweight. BJOG. 2000;107:896-902.
22. Friis ML, Kristensen O, Boas J, et al. Therapeutic experiences with 947 epileptic out-patients in oxcarbazepine treatment. Acta Neurol Scand. 1993;87:224-227.
23. Jedrzejczak J, Greese-Lyko M. Evaluation of teratogenic effects of the new generation of anti-epileptic drugs. Epilepsia. 2002;43:158.
24. Wide K, Winbladh B, Kallen B. Major malformations in infants exposed to antiepileptic drugs in utero, with emphasis on carbamazepine and valproic acid: a nation-wide, population-based register study. Acta Paediatr. 2004;93:174-176.
25. Bulau P, Paar WD, von Unruh GE. Pharmacokinetics of oxcarbazepine and 10-hydroxy-carbazepine in the newborn child of an oxcarbazepine-treated mother. Eur J Clin Pharmacol. 1988;34:311-313.