Increased proinflammatory cytokine and chemokine responses and microglial infection following inoculation with neural stem cells infected with polytropic murine retroviruses

Virology

Volumn 354, Issue 1, 2006, Pages 143-153

  Peterson, Karin E ^a   Evans, Leonard H ^b   Wehrly, Kathy ^b   Chesebro, Bruce ^b  

^a LOUISIANA STATE UNIVERSITY   (United States)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

Brain; Chemokines; Cytokines; Microglia; Mouse; Neuropathogenesis; Retrovirus

Indexed keywords

CHEMOKINE; CYTOKINE; MESSENGER RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; INOCULATION; MICROGLIA; MOUSE; NEURAL STEM CELL; NEUROLOGIC DISEASE; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; RETROVIRUS; VIRUS INFECTION;

ANIMALS; ASTROCYTES; BRAIN; CENTRAL NERVOUS SYSTEM VIRAL DISEASES; CHEMOKINES; CYTOKINES; DISEASE MODELS, ANIMAL; GENE EXPRESSION; IMMUNOHISTOCHEMISTRY; MICE; MICROGLIA; NEURONS; RECEPTORS, VIRUS; RETROVIRIDAE; RETROVIRIDAE INFECTIONS; RNA, MESSENGER; STEM CELL TRANSPLANTATION; STEM CELLS; VIRAL PROTEINS;

MURINAE;

EID: 33748956331     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2006.06.016     Document Type: Article

References (39)

1. Bajetto A., Bonavia R., Barbero S., Florio T., and Schettini G. Chemokines and their receptors in the central nervous system. Front. Neuroendocrinol. 22 (2001) 147-184
2. Boring L., Gosling J., Monteclaro F.S., Lusis A.J., Tsou C.L., and Charo I.F. Molecular cloning and functional expression of murine JE (monocyte chemoattractant protein 1) and murine macrophage inflammatory protein 1alpha receptors: evidence for two closely linked C-C chemokine receptors on chromosome 9. J. Biol. Chem. 271 (1996) 7551-7558
3. Choe W., Volsky D.J., and Potash M.J. Induction of rapid and extensive beta-chemokine synthesis in macrophages by human immunodeficiency virus type 1 and gp120, independently of their coreceptor phenotype. J. Virol. 75 (2001) 10738-10745
4. Conant K., Garzino-Demo A., Nath A., McArthur J.C., Halliday W., Power C., Gallo R.C., and Major E.O. Induction of monocyte chemoattractant protein-1 in HIV-1 Tat-stimulated astrocytes and elevation in AIDS dementia. Proc. Natl. Acad. Sci. U.S.A. 95 (1998) 3117-3121
5. Dimcheff D.E., Askovic S., Baker A.H., Johnson-Fowler C., and Portis J.L. Endoplasmic reticulum stress is a determinant of retrovirus-induced spongiform neurodegeneration. J. Virol. 77 (2003) 12617-12629
6. Dimcheff D.E., Faasse M.A., McAtee F.J., and Portis J.L. Endoplasmic reticulum (ER) stress induced by a neurovirulent mouse retrovirus is associated with prolonged BiP binding and retention of a viral protein in the ER. J. Biol. Chem. 279 (2004) 33782-33790
7. Eikelenboom P., Bate C., Van Gool W.A., Hoozemans J.J., Rozemuller J.M., Veerhuis R., and Williams A. Neuroinflammation in Alzheimer's disease and prion disease. Glia 40 (2002) 232-239
8. Evans L.H., and Morrey J.D. Tissue-specific replication of Friend and Moloney murine leukemia viruses in infected mice. J. Virol. 61 (1987) 1350-1357
9. Glabinski A.R., Balasingam V., Tani M., Kunkel S.L., Strieter R.M., Yong V.W., and Ransohoff R.M. Chemokine monocyte chemoattractant protein-1 is expressed by astrocytes after mechanical injury to the brain. J. Immunol. 156 (1996) 4363-4368
10. Glass J.D., Wesselingh S.L., Selnes O.A., and McArthur J.C. Clinical-neuropathologic correlation in HIV-associated dementia. [see comments]. Neurology 43 (1993) 2230-2237
11. Gonzalez E., Rovin B.H., Sen L., Cooke G., Dhanda R., Mummidi S., Kulkarni H., Bamshad M.J., Telles V., Anderson S.A., Walter E.A., Stephan K.T., Deucher M., Mangano A., Bologna R., Ahuja S.S., Dolan M.J., and Ahuja S.K. HIV-1 infection and AIDS dementia are influenced by a mutant MCP-1 allele linked to increased monocyte infiltration of tissues and MCP-1 levels. Proc. Natl. Acad. Sci. U.S.A. 99 (2002) 13795-13800
12. Hasenkrug K.J., Robertson S.J., Porti J., McAtee F., Nishio J., and Chesebro B. Two separate envelope regions influence induction of brain disease by a polytropic murine retrovirus (FMCF98). J. Virol. 70 (1996) 4825-4828
13. Kim J.W., Closs E.I., Albritton L.M., and Cunningham J.M. Transport of cationic amino acids by the mouse ecotropic retrovirus receptor. Nature 352 (1991) 725-728
14. Kim H.T., Waters K., Stoica G., Qiang W., Liu N., Scofield V.L., and Wong P.K. Activation of endoplasmic reticulum stress signaling pathway is associated with neuronal degeneration in MoMuLV-ts1-induced spongiform encephalomyelopathy. Lab. Invest. 84 (2004) 816-827
15. Lavignon M., and Evans L. A multistep process of leukemogenesis in Moloney murine leukemia virus-infected mice that is modulated by retroviral pseudotyping and interference. J. Virol. 70 (1996) 3852-3862
16. Liu N., Kuang X., Kim H.T., Stoica G., Qiang W., Scofield V.L., and Wong P.K. Possible involvement of both endoplasmic reticulum- and mitochondria-dependent pathways in MoMuLV-ts1-induced apoptosis in astrocytes. J. Neurovirol. 10 (2004) 189-198
17. Lynch W.P., Sharpe A.H., and Snyder E.Y. Neural stem cells as engraftable packaging lines can mediate gene delivery to microglia: evidence from studying retroviral env-related neurodegeneration. J. Virol. 73 (1999) 6841-6851
18. Mahad D.J., and Ransohoff R.M. The role of MCP-1 (CCL2) and CCR2 in multiple sclerosis and experimental autoimmune encephalomyelitis (EAE). Semin. Immunol. 15 (2003) 23-32
19. McManus C., Berman J.W., Brett F.M., Staunton H., Farrell M., and Brosnan C.F. MCP-1, MCP-2 and MCP-3 expression in multiple sclerosis lesions: an immunohistochemical and in situ hybridization study. J. Neuroimmunol. 86 (1998) 20-29
20. Mennicken F., Maki R., de Souza E.B., and Quirion R. Chemokines and chemokine receptors in the CNS: a possible role in neuroinflammation and patterning. Trends Pharmacol. Sci. 20 (1999) 73-78
21. Peterson K.E., Robertson S.J., Portis J.L., and Chesebro B. Differences in cytokine and chemokine responses during neurological disease induced by polytropic murine retroviruses Map to separate regions of the viral envelope gene. J. Virol. 75 (2001) 2848-2856
22. Peterson K.E., Errett J.S., Wei T., Dimcheff D.E., Ransohoff R., Kuziel W.A., Evans L., and Chesebro B. MCP-1 and CCR2 contribute to non-lymphocyte-mediated brain disease induced by Fr98 polytropic retrovirus infection in mice: role for astrocytes in retroviral neuropathogenesis. J. Virol. 78 (2004) 6449-6458
23. Peterson K.E., Hughes S., Dimcheff D.E., Wehrly K., and Chesebro B. Separate sequences in a murine retroviral envelope protein mediate neuropathogenesis by complementary mechanisms with differing requirements for tumor necrosis factor alpha. J. Virol. 78 (2004) 13104-13112
24. Portis J.L., Czub S., Robertson S., McAtee F., and Chesebro B. Characterization of a neurologic disease induced by a polytropic murine retrovirus: evidence for differential targeting of ecotropic and polytropic viruses in the brain. J. Virol. 69 (1995) 8070-8075
25. Post T.W., Bozic C.R., Rothenberg M.E., Luster A.D., Gerard N., and Gerard C. Molecular characterization of two murine eosinophil beta chemokine receptors. J. Immunol. 155 (1995) 5299-5305
26. Poulsen D.J., Robertson S.J., Favara C.A., Portis J.L., and Chesebro B.W. Mapping of a neurovirulence determinant within the envelope protein of a polytropic murine retrovirus: induction of central nervous system disease by low levels of virus. Virology 248 (1998) 199-207
27. Poulsen D.J., Favara C., Snyder E.Y., Portis J., and Chesebro B. Increased neurovirulence of polytropic mouse retroviruses delivered by inoculation of brain with infected neural stem cells. Virology 263 (1999) 23-29
28. Robertson M.N., Miyazawa M., Mori S., Caughey B., Evans L.H., Hayes S.F., and Chesebro B. Production of monoclonal antibodies reactive with a denatured form of the Friend murine leukemia virus gp70 envelope protein: use in a focal infectivity assay, immunohistochemical studies, electron microscopy and Western blotting. J. Virol. Methods 34 (1991) 255-271
29. Robertson S.J., Hasenkrug K.J., Chesebro B., and Portis J.L. Neurologic disease induced by polytropic murine retroviruses: neurovirulence determined by efficiency of spread to microglial cells. J. Virol. 71 (1997) 5287-5294
30. Sitbon M., Nishio J., Wehrly K., Lodmell D., and Chesebro B. Use of a focal immunofluorescence assay on live cells for quantitation of retroviruses: distinction of host range classes in virus mixtures and biological cloning of dual-tropic murine leukemia viruses. Virology 141 (1985) 110-118
31. Sun Y.X., Minthon L., Wallmark A., Warkentin S., Blennow K., and Janciauskiene S. Inflammatory markers in matched plasma and cerebrospinal fluid from patients with Alzheimer's disease. Dement. Geriatr. Cogn. Disord. 16 (2003) 136-144
32. Tailor C.S., Nouri A., Lee C.G., Kozak C., and Kabat D. Cloning and characterization of a cell surface receptor for xenotropic and polytropic murine leukemia viruses. Proc. Natl. Acad. Sci. U.S.A. 96 (1999) 927-932
33. Traister R.S., and Lynch W.P. Reexamination of amphotropic murine leukemia virus neurovirulence: neural stem cell-mediated microglial infection fails to induce acute neurodegeneration. Virology 293 (2002) 262-272
34. VanDer V., Tekstra J., Beelen R.H., Tensen C.P., VanDer V., and De Groot C.J. Expression of MCP-1 by reactive astrocytes in demyelinating multiple sclerosis lesions. Am. J. Pathol. 154 (1999) 45-51
35. Wang H., Kavanaugh M.P., North R.A., and Kabat D. Cell-surface receptor for ecotropic murine retroviruses is a basic amino-acid transporter. Nature 352 (1991) 729-731
36. Wehrly K., and Chesebro B. p24 Antigen capture assay for quantification of human immunodeficiency virus using readily available inexpensive reagents. Methods 12 (1997) 288-293
37. Wesselingh S.L., Power C., Glass J.D., Tyor W.R., McArthur J.C., Farber J.M., Griffin J.W., and Griffin D.E. Intracerebral cytokine messenger RNA expression in acquired immunodeficiency syndrome dementia. Ann. Neurol. 33 (1993) 576-582
38. Xia M.Q., and Hyman B.T. Chemokines/chemokine receptors in the central nervous system and Alzheimer's disease. J. Neurovirol. 5 (1999) 32-41
39. Yang Y.L., Guo L., Xu S., Holland C.A., Kitamura T., Hunter K., and Cunningham J.M. Receptors for polytropic and xenotropic mouse leukaemia viruses encoded by a single gene at Rmc1. Nat. Genet. 21 (1999) 216-219