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Volumn 71, Issue 7, 1997, Pages 5287-5294

Neurologic disease induced by polytropic murine retroviruses: Neurovirulence determined by efficiency of spread to microglial cells

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ARTICLE; ASTROCYTOSIS; CELL VACUOLE; CENTRAL NERVOUS SYSTEM; CORPUS CALLOSUM; ENVELOPE GENE; MICROGLIA; NEUROLOGIC DISEASE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RETROVIRUS; VIRUS INDUCTION; VIRUS ISOLATION; VIRUS VIRULENCE;

EID: 0030960347     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.71.7.5287-5294.1997     Document Type: Article
Times cited : (39)

References (52)
  • 3
    • 0025200468 scopus 로고
    • Murine retroviral-induced spongiform neuronal degeneration parallels resident microglial cell infection: Ultrastructural findings
    • Baszler, T. V., and J. F. Zachary. 1990. Murine retroviral-induced spongiform neuronal degeneration parallels resident microglial cell infection: ultrastructural findings. Lab. Invest. 63:612-623.
    • (1990) Lab. Invest. , vol.63 , pp. 612-623
    • Baszler, T.V.1    Zachary, J.F.2
  • 4
    • 0026083185 scopus 로고
    • Murine retroviral neurovirulence correlates with an enhanced ability of virus to infect selectively, replicate in, and activate resident microglial cells
    • Baszler, T. V., and J. F. Zachary. 1991. Murine retroviral neurovirulence correlates with an enhanced ability of virus to infect selectively, replicate in, and activate resident microglial cells. Am. J. Pathol. 138:655-671.
    • (1991) Am. J. Pathol. , vol.138 , pp. 655-671
    • Baszler, T.V.1    Zachary, J.F.2
  • 5
    • 0022538744 scopus 로고
    • Characterization of a progressive neurodegenerative disease induced by a temperature-sensitive Moloney murine leukemia virus infection
    • Bilello, J. A., O. M. Pitts, and P. M. Hoffman. 1986. Characterization of a progressive neurodegenerative disease induced by a temperature-sensitive Moloney murine leukemia virus infection. J. Virol. 59:234-241.
    • (1986) J. Virol. , vol.59 , pp. 234-241
    • Bilello, J.A.1    Pitts, O.M.2    Hoffman, P.M.3
  • 6
    • 0025017821 scopus 로고
    • Host genes conferring resistance to a central nervous system disease induced by a polytropic recombinant Friend murine retrovirus
    • Buller, R. S., K. Wehrly, J. L. Portis, and B. Chesebro. 1990. Host genes conferring resistance to a central nervous system disease induced by a polytropic recombinant Friend murine retrovirus. J. Virol. 64:493-498.
    • (1990) J. Virol. , vol.64 , pp. 493-498
    • Buller, R.S.1    Wehrly, K.2    Portis, J.L.3    Chesebro, B.4
  • 7
    • 0021893991 scopus 로고
    • Different murine cell lines manifest unique patterns of interference to superinfection by murine leukemia viruses
    • Chesebro, B., and K. Wehrly. 1985. Different murine cell lines manifest unique patterns of interference to superinfection by murine leukemia viruses. Virology 141:119-129.
    • (1985) Virology , vol.141 , pp. 119-129
    • Chesebro, B.1    Wehrly, K.2
  • 9
    • 0025879347 scopus 로고
    • Age-dependent resistance to murine retrovirus-induced spongiform neurodegeneration results from central nervous system-specific restriction of virus replication
    • Czub, M., S. Czub, F. J. McAtee, and J. L. Portis. 1991. Age-dependent resistance to murine retrovirus-induced spongiform neurodegeneration results from central nervous system-specific restriction of virus replication. J. Virol. 65:2539-2544.
    • (1991) J. Virol. , vol.65 , pp. 2539-2544
    • Czub, M.1    Czub, S.2    McAtee, F.J.3    Portis, J.L.4
  • 10
    • 0026629484 scopus 로고
    • Murine retrovirus-induced spongiform encephalomyelopathy: Host and viral factors which determine the length of the incubation period
    • Czub, M., F. J. McAtee, and J. L. Portis. 1992. Murine retrovirus-induced spongiform encephalomyelopathy: host and viral factors which determine the length of the incubation period. J. Virol. 66:3298-3305.
    • (1992) J. Virol. , vol.66 , pp. 3298-3305
    • Czub, M.1    McAtee, F.J.2    Portis, J.L.3
  • 11
    • 0028179115 scopus 로고
    • Kinetic analysis of spongiform neurodegenerative disease induced by a highly virulent murine retrovirus
    • Czub, S., W. P. Lynch, M. Czub, and J. L. Portis. 1994. Kinetic analysis of spongiform neurodegenerative disease induced by a highly virulent murine retrovirus. Lab. Invest. 70:711-723.
    • (1994) Lab. Invest. , vol.70 , pp. 711-723
    • Czub, S.1    Lynch, W.P.2    Czub, M.3    Portis, J.L.4
  • 12
    • 0021687214 scopus 로고
    • Physical mapping of the paralysis-inducing determinant of a wild mouse ecotropic neurotropic virus
    • DesGroseillers, L., M. Barrette, and P. Jolicoeur. 1984. Physical mapping of the paralysis-inducing determinant of a wild mouse ecotropic neurotropic virus. J. Virol. 52:356-363.
    • (1984) J. Virol. , vol.52 , pp. 356-363
    • DesGroseillers, L.1    Barrette, M.2    Jolicoeur, P.3
  • 13
    • 0027354484 scopus 로고
    • Microglia and cytokine in neurological disease, with special reference to AIDS and Alzheimer's disease
    • Dickson, D. W., S. C. Lee, L. A. Mattiace, S.-H. C. Yen, and C. Brosnan. 1993. Microglia and cytokine in neurological disease, with special reference to AIDS and Alzheimer's disease. Glia 7:75-83.
    • (1993) Glia , vol.7 , pp. 75-83
    • Dickson, D.W.1    Lee, S.C.2    Mattiace, L.A.3    Yen, S.-H.C.4    Brosnan, C.5
  • 15
    • 0026440742 scopus 로고
    • Cytokines and arachidonic metabolites produced during human immunodeficiency virus (HIV)-infected macrophage-astroglia interactions: Implications for the neuropathogenesis of HIV disease
    • Genis, P., M. Jett, E. W. Bernton, T. Boyle, H. A. Gelbard, K. Dzenko, R. W. Keane, L. Resnick, Y. Mizrachi, D. J. Volsky, L. G. Epstein, and H. E. Gendelman. 1992. Cytokines and arachidonic metabolites produced during human immunodeficiency virus (HIV)-infected macrophage-astroglia interactions: implications for the neuropathogenesis of HIV disease. J. Exp. Med. 176:1703-1718.
    • (1992) J. Exp. Med. , vol.176 , pp. 1703-1718
    • Genis, P.1    Jett, M.2    Bernton, E.W.3    Boyle, T.4    Gelbard, H.A.5    Dzenko, K.6    Keane, R.W.7    Resnick, L.8    Mizrachi, Y.9    Volsky, D.J.10    Epstein, L.G.11    Gendelman, H.E.12
  • 16
    • 0025609978 scopus 로고
    • Secretion of neurotoxins by mononuclear phagocytes infected with HIV-1
    • Giulian, D., K. Vaca, and C. A. Noonan. 1990. Secretion of neurotoxins by mononuclear phagocytes infected with HIV-1. Science 250:1593-1596.
    • (1990) Science , vol.250 , pp. 1593-1596
    • Giulian, D.1    Vaca, K.2    Noonan, C.A.3
  • 17
    • 0028808135 scopus 로고
    • Immunocytochemical quantitation of human immunodeficiency virus in the brain: Correlations with dementia
    • Glass, J. D., H. Fedor, S. L. Wesselingh, and J. C. McArthur. 1995. Immunocytochemical quantitation of human immunodeficiency virus in the brain: correlations with dementia. Ann. Neurol. 38:755-762.
    • (1995) Ann. Neurol. , vol.38 , pp. 755-762
    • Glass, J.D.1    Fedor, H.2    Wesselingh, S.L.3    McArthur, J.C.4
  • 18
    • 0027490716 scopus 로고
    • Evidence that retroviruses integrate into post-replication host DNA
    • Hajihosseini, M., L. Iavachev, and J. Price. 1993. Evidence that retroviruses integrate into post-replication host DNA. EMBO J. 12:4969-74.
    • (1993) EMBO J. , vol.12 , pp. 4969-4974
    • Hajihosseini, M.1    Iavachev, L.2    Price, J.3
  • 19
    • 0030000113 scopus 로고    scopus 로고
    • Two separate envelope regions influence induction of brain disease by a polytropic murine retrovirus (FMCF98)
    • Hasenkrug, K. J., S. J. Robertson, J. Portis, F. McAtee, J. Nishio, and B. Chesebro. 1996. Two separate envelope regions influence induction of brain disease by a polytropic murine retrovirus (FMCF98). J. Virol. 70:4825-4828.
    • (1996) J. Virol. , vol.70 , pp. 4825-4828
    • Hasenkrug, K.J.1    Robertson, S.J.2    Portis, J.3    McAtee, F.4    Nishio, J.5    Chesebro, B.6
  • 20
    • 0026775203 scopus 로고
    • Cellular tropism and localization in the rodent nervous system of a neuropathogenic variant of Friend murine leukemia virus
    • Hoffman, P. M., E. F. Cimino, D. S. Robbins, R. D. Broadwell, J. M. Powers, and S. K. Ruscetti. 1992. Cellular tropism and localization in the rodent nervous system of a neuropathogenic variant of Friend murine leukemia virus. Lab. Invest. 67:314-321.
    • (1992) Lab. Invest. , vol.67 , pp. 314-321
    • Hoffman, P.M.1    Cimino, E.F.2    Robbins, D.S.3    Broadwell, R.D.4    Powers, J.M.5    Ruscetti, S.K.6
  • 21
    • 0030001660 scopus 로고    scopus 로고
    • Quantitation of human immunodeficiency virus in brains of demented and nondemented patients with acquired immunodeficiency syndrome
    • Johnson, R. T., J. D. Glass, J. C. McArthur, and B. W. Chesebro. 1996. Quantitation of human immunodeficiency virus in brains of demented and nondemented patients with acquired immunodeficiency syndrome. Ann. Neurol. 39:392-395.
    • (1996) Ann. Neurol. , vol.39 , pp. 392-395
    • Johnson, R.T.1    Glass, J.D.2    McArthur, J.C.3    Chesebro, B.W.4
  • 22
    • 0023797112 scopus 로고
    • The neurobiology of human immunodeficiency virus infections
    • Johnson, R. T., J. C. McArthur, and O. Narayan. 1988. The neurobiology of human immunodeficiency virus infections. FASEB J. 2:2970-2981.
    • (1988) FASEB J. , vol.2 , pp. 2970-2981
    • Johnson, R.T.1    McArthur, J.C.2    Narayan, O.3
  • 23
    • 0021262181 scopus 로고
    • Isolation of paralysis-inducing murine leukemia viruses from Friend virus passaged in rats
    • Kai, K., and T. Furuta. 1984. Isolation of paralysis-inducing murine leukemia viruses from Friend virus passaged in rats. J. Virol. 50:970-973.
    • (1984) J. Virol. , vol.50 , pp. 970-973
    • Kai, K.1    Furuta, T.2
  • 25
    • 0026006927 scopus 로고
    • Murine retrovirus-induced spongiform encephalopathy: Productive infection of microglia and cerebellar neurons in accelerated CNS disease
    • Lynch, W. P., S. Czub, F. J. McAtee, S. F. Hayes, and J. L. Portis. 1991. Murine retrovirus-induced spongiform encephalopathy: productive infection of microglia and cerebellar neurons in accelerated CNS disease. Neuron 7:365-379.
    • (1991) Neuron , vol.7 , pp. 365-379
    • Lynch, W.P.1    Czub, S.2    McAtee, F.J.3    Hayes, S.F.4    Portis, J.L.5
  • 26
    • 0027401708 scopus 로고
    • Murine retrovirus-induced spongiform encephalopathy: Disease expression is dependent on postnatal development of the central nervous system
    • Lynch, W. P., and J. L. Portis. 1993. Murine retrovirus-induced spongiform encephalopathy: disease expression is dependent on postnatal development of the central nervous system. J. Virol. 67:2601-2610.
    • (1993) J. Virol. , vol.67 , pp. 2601-2610
    • Lynch, W.P.1    Portis, J.L.2
  • 27
    • 0028814993 scopus 로고
    • Induction of focal spongiform neurodegeneration in developmentally resistant mice by implantation of murine retrovirus-infected microglia
    • Lynch, W. P., S. J. Robertson, and J. L. Portis. 1995. Induction of focal spongiform neurodegeneration in developmentally resistant mice by implantation of murine retrovirus-infected microglia. J. Virol. 69:1408-1419.
    • (1995) J. Virol. , vol.69 , pp. 1408-1419
    • Lynch, W.P.1    Robertson, S.J.2    Portis, J.L.3
  • 28
    • 0029959866 scopus 로고    scopus 로고
    • Late virus replication events in microglia are required for neurovirulent retrovirus-induced spongiform neurodegeneration: Evidence from neural progenitor-derived chimeric mouse brains
    • Lynch, W. P., E. Y. Snyder, L. Qualtiere, J. L. Portis, and A. H. Sharpe. 1996. Late virus replication events in microglia are required for neurovirulent retrovirus-induced spongiform neurodegeneration: evidence from neural progenitor-derived chimeric mouse brains. J. Virol. 70:8896-8907.
    • (1996) J. Virol. , vol.70 , pp. 8896-8907
    • Lynch, W.P.1    Snyder, E.Y.2    Qualtiere, L.3    Portis, J.L.4    Sharpe, A.H.5
  • 30
    • 0016335085 scopus 로고
    • Periodate-lysine-paraformaldehyde fixative: A new fixative for immunoelectron microscopy
    • McLean, I. W., and P. K. Nakane. 1974. Periodate-lysine-paraformaldehyde fixative: a new fixative for immunoelectron microscopy. J. Histochem. Cytochem. 22:1077-1083.
    • (1974) J. Histochem. Cytochem. , vol.22 , pp. 1077-1083
    • McLean, I.W.1    Nakane, P.K.2
  • 31
    • 0026598118 scopus 로고
    • Cognitive and motor impairments associated with SIV infection in rhesus monkeys
    • Murray, E. A., D. M. Rausch, J. Lendvay, L. R. Sharer, and L. E. Eiden. 1992. Cognitive and motor impairments associated with SIV infection in rhesus monkeys. Science 255:1246-1249.
    • (1992) Science , vol.255 , pp. 1246-1249
    • Murray, E.A.1    Rausch, D.M.2    Lendvay, J.3    Sharer, L.R.4    Eiden, L.E.5
  • 32
    • 0022518134 scopus 로고
    • The AIDS dementia complex. I. Clinical features
    • Navia, B. A., B. D. Jordan, and R. W. Price. 1986. The AIDS dementia complex. I. Clinical features. Ann. Neurol. 19:517-524.
    • (1986) Ann. Neurol. , vol.19 , pp. 517-524
    • Navia, B.A.1    Jordan, B.D.2    Price, R.W.3
  • 33
    • 0020604428 scopus 로고
    • Molecular cloning of Friend mink cell focus-inducing virus: Identification of mink cell focus-inducing virus-like messages in normal and transformed cells
    • Oliff, A., L. Collins, and C. Mirenda. 1983. Molecular cloning of Friend mink cell focus-inducing virus: identification of mink cell focus-inducing virus-like messages in normal and transformed cells. J. Virol. 48:542-546.
    • (1983) J. Virol. , vol.48 , pp. 542-546
    • Oliff, A.1    Collins, L.2    Mirenda, C.3
  • 34
    • 0016913939 scopus 로고
    • Maedi and visna in sheep
    • R. H. Kimberlin (ed.), North Holland Publishing Co., Amsterdam, The Netherlands
    • Palsson, P. A. 1976. Maedi and visna in sheep, p. 17-43. In R. H. Kimberlin (ed.), Slow virus diseases of animals and man. North Holland Publishing Co., Amsterdam, The Netherlands.
    • (1976) Slow Virus Diseases of Animals and Man , pp. 17-43
    • Palsson, P.A.1
  • 35
    • 0027182169 scopus 로고
    • Intracerebral hemorrhages and syncytium formation induced by endothelial cell infection with a murine leukemia virus
    • Park, B. H., E. Lavi, K. J. Blank, and G. N. Gaulton. 1993. Intracerebral hemorrhages and syncytium formation induced by endothelial cell infection with a murine leukemia virus. J. Virol. 67:6015-6024.
    • (1993) J. Virol. , vol.67 , pp. 6015-6024
    • Park, B.H.1    Lavi, E.2    Blank, K.J.3    Gaulton, G.N.4
  • 38
    • 0025213982 scopus 로고
    • Neurodegenerative disease induced by the wild mouse ecotropic retrovirus is markedly accelerated by long terminal repeat and gag-pol sequences from nondefective Friend murine leukemia virus
    • Portis, J. L., S. Czub, C. F. Garon, and F. J. McAtee. 1990. Neurodegenerative disease induced by the wild mouse ecotropic retrovirus is markedly accelerated by long terminal repeat and gag-pol sequences from nondefective Friend murine leukemia virus. J. Virol. 64:1648-1656.
    • (1990) J. Virol. , vol.64 , pp. 1648-1656
    • Portis, J.L.1    Czub, S.2    Garon, C.F.3    McAtee, F.J.4
  • 39
    • 0028826123 scopus 로고
    • Characterization of a neurologic disease induced by a polytropic murine retrovirus: Evidence for differential targeting of ecotropic and polytropic viruses in the brain
    • Portis, J. L., S. Czub, S. Robertson, F. McAtee, and B. Chesebro. 1995. Characterization of a neurologic disease induced by a polytropic murine retrovirus: evidence for differential targeting of ecotropic and polytropic viruses in the brain. J. Virol. 69:8070-8075.
    • (1995) J. Virol. , vol.69 , pp. 8070-8075
    • Portis, J.L.1    Czub, S.2    Robertson, S.3    McAtee, F.4    Chesebro, B.5
  • 40
    • 0023832296 scopus 로고
    • The brain in AIDS: Central nervous system HIV-1 infection and AIDS dementia complex
    • Price, R. W., B. Brew, J. Sidtis, M. Rosenblum, A. C. Scheck, and P. Cleary. 1988. The brain in AIDS: central nervous system HIV-1 infection and AIDS dementia complex. Science 239:586-592.
    • (1988) Science , vol.239 , pp. 586-592
    • Price, R.W.1    Brew, B.2    Sidtis, J.3    Rosenblum, M.4    Scheck, A.C.5    Cleary, P.6
  • 42
    • 0020079047 scopus 로고
    • Interference grouping of murine leukemia viruses: A distinct receptor for the MCF-recombinant viruses in mouse cells
    • Rein, A. 1982. Interference grouping of murine leukemia viruses: a distinct receptor for the MCF-recombinant viruses in mouse cells. Virology 120:251-257.
    • (1982) Virology , vol.120 , pp. 251-257
    • Rein, A.1
  • 43
    • 0026742290 scopus 로고
    • Derivation of neurotropic simian immunodeficiency virus from exclusively lymphocyte-tropic parental virus: Pathogenesis of infection in macaques
    • Sharma, D. P., M. C. Zink, M. Anderson, R. Adams, J. E. Clements, S. V. Joag, and O. Narayan. 1992. Derivation of neurotropic simian immunodeficiency virus from exclusively lymphocyte-tropic parental virus: pathogenesis of infection in macaques. J. Virol. 66:3550-3556.
    • (1992) J. Virol. , vol.66 , pp. 3550-3556
    • Sharma, D.P.1    Zink, M.C.2    Anderson, M.3    Adams, R.4    Clements, J.E.5    Joag, S.V.6    Narayan, O.7
  • 44
    • 0021985833 scopus 로고
    • Use of a focal immunofluorescence assay on live cells for quantitation of retroviruses. Distinction of host-range classes in virus mixtures and biological cloning of dual-tropic murine leukemia viruses
    • Sitbon, M., J. Nishio, K. Wehrly, D. Lodmell, and B. Chesebro. 1985. Use of a focal immunofluorescence assay on live cells for quantitation of retroviruses. Distinction of host-range classes in virus mixtures and biological cloning of dual-tropic murine leukemia viruses. Virology 141:110-118.
    • (1985) Virology , vol.141 , pp. 110-118
    • Sitbon, M.1    Nishio, J.2    Wehrly, K.3    Lodmell, D.4    Chesebro, B.5
  • 45
    • 0022919696 scopus 로고
    • Hemolytic anemia and erythroleukemia, two distinct pathogenic effects of Friend MuLV: Mapping of the effects to different regions of the viral genome
    • Sitbon, M., B. Sola, L. Evans, J. Nishio, S. F. Hayes, K. Nathanson, C. F. Garon, and B. Chesebro. 1986. Hemolytic anemia and erythroleukemia, two distinct pathogenic effects of Friend MuLV: mapping of the effects to different regions of the viral genome. Cell 47:851-859.
    • (1986) Cell , vol.47 , pp. 851-859
    • Sitbon, M.1    Sola, B.2    Evans, L.3    Nishio, J.4    Hayes, S.F.5    Nathanson, K.6    Garon, C.F.7    Chesebro, B.8
  • 46
    • 0029042524 scopus 로고
    • Early intrathecal events in rhesus macaques (Macaca mulatta) infected with pathogenic or nonpathogenic molecular clones of simian immunodeficiency virus
    • Smith, M. O., M. P. Heyes, and A. A. Lackner. 1995. Early intrathecal events in rhesus macaques (Macaca mulatta) infected with pathogenic or nonpathogenic molecular clones of simian immunodeficiency virus. Lab. Invest. 72: 547-557.
    • (1995) Lab. Invest. , vol.72 , pp. 547-557
    • Smith, M.O.1    Heyes, M.P.2    Lackner, A.A.3
  • 47
    • 0018758819 scopus 로고
    • Mac-1: A macrophage differentiation antigen identified by monoclonal antibody
    • Springer, T., G. Galfre, D. S. Secher, and C. Milstein. 1979. Mac-1: a macrophage differentiation antigen identified by monoclonal antibody. Eur. J. Immunol. 9:301-306.
    • (1979) Eur. J. Immunol. , vol.9 , pp. 301-306
    • Springer, T.1    Galfre, G.2    Secher, D.S.3    Milstein, C.4
  • 48
    • 0028874911 scopus 로고
    • Lymphocyte-tropic simian immunodeficiency virus causes persistent infection in the brains of rhesus monkeys
    • Stephens, E. B., Z. Q. Liu, G. W. Zhu, J. Adany, S. V. Joag, L. Foresman. N. E. J. Berman, and O. Narayan. 1995. Lymphocyte-tropic simian immunodeficiency virus causes persistent infection in the brains of rhesus monkeys. Virology 213:600-614.
    • (1995) Virology , vol.213 , pp. 600-614
    • Stephens, E.B.1    Liu, Z.Q.2    Zhu, G.W.3    Adany, J.4    Joag, S.V.5    Foresman, L.6    Berman, N.E.J.7    Narayan, O.8
  • 49
    • 0029945512 scopus 로고    scopus 로고
    • Localization of HIV-1 in human brain using polymerase chain reaction/in situ hybridization and immunocytochemistry
    • Takahashi, K., S. L. Wesselingh, D. E. Griffin, J. C. McArthur, R. T. Johnson, and J. D. Glass. 1996. Localization of HIV-1 in human brain using polymerase chain reaction/in situ hybridization and immunocytochemistry. Ann. Neurol. 39:705-711.
    • (1996) Ann. Neurol. , vol.39 , pp. 705-711
    • Takahashi, K.1    Wesselingh, S.L.2    Griffin, D.E.3    McArthur, J.C.4    Johnson, R.T.5    Glass, J.D.6
  • 50
    • 0023678987 scopus 로고
    • Cellular and subcellular distribution of 2′,3′-cyclic nucleotide 3′-phosphodiesterase and its mRNA in the rat central nervous system
    • Trapp, B. D., L. Bernier, S. B. Andrews, and D. R. Colman. 1988. Cellular and subcellular distribution of 2′,3′-cyclic nucleotide 3′-phosphodiesterase and its mRNA in the rat central nervous system. J. Neurochem. 51:8597-868.
    • (1988) J. Neurochem. , vol.51 , pp. 8597-8868
    • Trapp, B.D.1    Bernier, L.2    Andrews, S.B.3    Colman, D.R.4
  • 51
    • 0027155943 scopus 로고
    • The pathogenesis of murine retroviral infection of the central nervous system
    • Wiley, C. A., and M. Gardner. 1993. The pathogenesis of murine retroviral infection of the central nervous system. Brain Pathol. 3:123-128.
    • (1993) Brain Pathol. , vol.3 , pp. 123-128
    • Wiley, C.A.1    Gardner, M.2
  • 52
    • 0025233572 scopus 로고
    • Moloney murine leukemia virus temperature-sensitive mutants: A model for retrovirus-induced neurologic disorders
    • Wong, P. K. Y. 1990. Moloney murine leukemia virus temperature-sensitive mutants: a model for retrovirus-induced neurologic disorders. Curr. Top. Microbiol. Immunol. 160:29-60.
    • (1990) Curr. Top. Microbiol. Immunol. , vol.160 , pp. 29-60
    • Wong, P.K.Y.1


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