Molecular and cellular regulation of neurotensin receptor under acute and chronic agonist stimulation

Peptides

Volumn 27, Issue 10, 2006, Pages 2493-2501

  Souazé, Frédérique ^a   Forgez, Patricia ^a  

^a HÔPITAL SAINT ANTOINE   (France)

Author keywords

Chronic agonist stimulation; G protein; Neurotensin receptor

Indexed keywords

2 [[1 (7 CHLORO 4 QUINOLINYL) 5 (2,6 DIMETHOXYPHENYL) 3 PYRAZOLYL]CARBONYLAMINO] 2 ADAMANTANECARBOXYLIC ACID; HORMONE RECEPTOR STIMULATING AGENT; MESSENGER RNA; NEUROTENSIN RECEPTOR; NEUROTENSIN RECEPTOR AGONIST; NEUROTENSIN RECEPTOR ANTAGONIST; UNCLASSIFIED DRUG;

AGONIST; CANCER CELL CULTURE; CELL FATE; CELL STRAIN COS7; CELL TRANSFORMATION; CELL TRANSPORT; CHRONIC DRUG ADMINISTRATION; DESENSITIZATION; DOSE TIME EFFECT RELATION; DRUG RECEPTOR BINDING; ENDOCYTOSIS; GENE ACTIVATION; GENE EXPRESSION REGULATION; GENE INDUCTION; GENE OVEREXPRESSION; HUMAN; IMMUNOCYTOCHEMISTRY; IMMUNOREACTIVITY; MESSENGER RNA SYNTHESIS; MICROTUBULE ASSEMBLY; NEUROENDOCRINOLOGY; PRESYNAPTIC NERVE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RECEPTOR AFFINITY; RECEPTOR INTRINSIC ACTIVITY; RETROGRADE NERVE FIBER TRANSPORT; REVIEW; SYNAPTOSOME;

ANIMALS; BIOLOGICAL TRANSPORT, ACTIVE; ENDOCYTOSIS; GENE EXPRESSION REGULATION; HUMANS; MEMBRANES; MODELS, NEUROLOGICAL; NEUROTENSIN; RECEPTORS, NEUROTENSIN; RECOMBINANT PROTEINS;

EID: 33748943788     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.peptides.2006.04.029     Document Type: Review

References (77)

1. Amar S., Kitabgi P., and Vincent J.P. Activation of phosphatidylinositol turnover by neurotensin receptors in the human colonic adenocarcinoma cell line HT29. FEBS Lett 201 1 (1986) 31-36
2. Azzi M., Boudin H., Mahmudi N., Pelaprat D., Rostene W., and Berod A. In vivo regulation of neurotensin receptors following long-term pharmacological blockade with a specific receptor antagonist. Brain Res Mol Brain Res 42 2 (1996) 213-221
3. Beaudet A., Nouel D., Stroh T., Vandenbulcke F., Dal Farra C., and Vincent J.P. Fluorescent ligands for studying neuropeptide receptors by confocal microscopy. Braz J Med Biol Res 31 11 (1998) 1479-1489
4. Belcheva M., Barg J., Rowinski J., Clark W.G., Gloeckner C.A., Ho A., et al. Novel opioid binding sites associated with nuclei of NG108-15 neurohybrid cells. J Neurosci 13 1 (1993) 104-114
5. Belcheva M.M., Gucker S., Chuang D.M., Clark W.G., Jefcoat L.B., McHale R.J., et al. Modulation of opioid binding associated with nuclear matrix and nuclear membranes of NG108-15 cells. J Pharmacol Exp Ther 274 3 (1995) 1513-1523
6. Bhattacharya M., Peri K., Ribeiro-Da-Silva A., Almazan G., Shichi H., Hou X., et al. Localization of functional prostaglandin E2 receptors EP3 and EP4 in the nuclear envelope. J Biol Chem 274 22 (1999) 15719-15724
7. Bhattacharya M., Peri K.G., Almazan G., Ribeiro-Da-Silva A., Shichi H., Durocher Y., et al. Nuclear localization of prostaglandin E2 receptors. Proc Natl Acad Sci USA 95 26 (1998) 15792-15797
8. Booz G.W., Conrad K.M., Hess A.L., Singer H.A., and Baker K.M. Angiotensin-II-binding sites on hepatocyte nuclei. Endocrinology 130 6 (1992) 3641-3649
9. Boudin H., Pelaprat D., Rostene W., Picket V.M., and Beaudet A. Correlative ultrastructural distribution of neurotensin receptor proteins and binding sites in the rat substantia nigra. J Neurosci 18 20 (1998) 8473-8484
10. Boudin H., Pelaprat D., Rostene W., Pickel V.M., and Beaudet A. Correlative ultrastructural distribution of neurotensin receptor proteins and binding sites in the rat substantia nigra. J Neurosci 18 20 (1998) 8473-8484
11. Brun P., Mastrotto C., Beggiao E., Stefani A., Barzon L., Sturniolo G.C., et al. Neuropeptide neurotensin stimulates intestinal wound healing following chronic intestinal inflammation. Am J Physiol Gastrointest Liver Physiol 288 4 (2005) G621-G629
12. Carraway R., and Leeman S.E. The isolation of a new hypotensive peptide, neurotensin, from bovine hypothalami. J Biol Chem 248 19 (1973) 6854-6861
13. Castagliuolo I., Wang C.C., Valenick L., Pasha A., Nikulasson S., Carraway R.E., et al. Neurotensin is a proinflammatory neuropeptide in colonic inflammation. J Clin Invest 103 6 (1999) 843-849
14. Castel M.N., Beaudet A., and Laduron P.M. Retrograde axonal transport of neurotensin in rat nigrostriatal dopaminergic neurons. Modulation during ageing and possible physiological role. Biochem Pharmacol 47 1 (1994) 53-62
15. Chabry J., Botto J.M., Nouel D., Beaudet A., Vincent J.P., and Mazella J. Thr-422 and Tyr-424 residues in the carboxyl terminus are critical for the intemalization of the rat neurotensin receptor. J Biol Chem 270 6 (1995) 2439-2442
16. Chabry J., Checler F., Vincent J.P., and Mazella J. Neurotensin receptor localization on neurons bearing the neurotensin-degrading enzyme endopeptidase 24-16. Ann NY Acad Sci 668 (1992) 326-328
17. Chalon P., Vita N., Kaghad M., Guillemot M., Bonnin J., Delpech B., et al. Molecular cloning of a levocabastine-sensitive neurotensin binding site. FEBS Lett 386 2/3 (1996) 91-94
18. Claing A. Regulation of G protein-coupled receptor endocytosis by ARF6 GTP-binding proteins. Biochem Cell Biol 82 6 (2004) 610-617
19. Dana C., Vial M., Leonard K., Beauregard A., Kitabgi P., Vincent J.P., et al. Electron microscopic localization of neurotensin binding sites in the midbrain tegmentum of the rat. I. Ventral tegmental area and the interfascicular nucleus. J Neurosci 9 7 (1989) 2247-2257
20. Donato D.P., Cusack B., Yamada M., and Richelson E. Desensitization and down-regulation of neurotensin receptors in murine neuroblastoma clone N1E-115 by [D-Lys8] neurotensin (8-13). J Pharmacol Exp Ther 264 1 (1993) 1-5
21. Eggena P., Zhu J.H., Clegg K., and Barrett J.D. Nuclear angiotensin receptors induce transcription of renin and angiotensinogen mRNA. Hypertension 22 4 (1993) 496-501
22. Elek J., Pinzon W., Park K.H., and Narayanan R. Relevant genomics of neurotensin receptor in cancer. Anticancer Res 20 1A (2000) 53-58
23. Evers B.M., Ishizuka J., Chung D.H., Townsend Jr. C.M., and Thompson J.C. Neurotensin expression and release in human colon cancers. Ann Surg 216 4 (1992) 423-430
24. Faure M.P., Alonso A., Nouel D., Gaudriault G., Dennis M., Vincent J.P., et al. Somatodendritic internalization and perinuclear targeting of neurotensin in the mammalian brain. J Neurosci 15 6 (1995) 4140-4147
25. Faure M.P., Nouel D., and Beaudet A. Axonal and dendritic transport of internalized neurotensin in rat mesostriatal dopaminergic neurons. Neuroscience 68 2 (1995) 519-529
26. Ferguson S.S. Evolving concepts in G protein-coupled receptor endocytosis: the role in receptor desensitization and signaling. Pharmacol Rev 53 1 (2001) 1-24
27. Feurle G.E., Helmstaedter V., Tischbirek K., Carraway R., Forssmann W.G., Grube D., et al. A multihormonal tumor of the pancreas producing neurotensin. Dig Dis Sci 26 12 (1981) 1125-1133
28. Gilbert J.A., Strobel T.R., and Richelson E. Desensitization of neurotensin receptor-mediated cyclic GMP formation in neuroblastoma clone N1E-115. Biochem Pharmacol 37 14 (1988) 2833-2838
29. Gobeil Jr. F., Dumont I., Marrache A.M., Vazquez-Tello A., Bernier S.G., Abran D., et al. Regulation of eNOS expression in brain endothelial cells by perinuclear EP(3) receptors. Circ Res 90 6 (2002) 682-689
30. Gullo L., Pezzilli R., Tomassetti P., and de Giorgio R. Plasma cholecystokinin and neurotensin after an ordinary meal in humans. A prolonged time study. Gastroenterol Clin Biol 22 1 (1998) 25-28
31. Hammer R.A., Carraway R.E., and Leeman S.E. Elevation of plasma neurotensinlike immunoreactivity after a meal. Characterization of the elevated components. J Clin Invest 70 1 (1982) 74-81
32. Hermans E., and Maloteaux J.M. Mechanisms of regulation of neurotensin receptors. Pharmacol Ther 79 2 (1998) 89-104
33. Hermans E., Octave J.N., and Maloteaux J.M. Interaction of the COOH-terminal domain of the neurotensin receptor with a G protein does not control the phospholipase C activation but is involved in the agonist-induced internalization. Mol Pharmacol 49 2 (1996) 365-372
34. Hermans E., Vanisberg M.A., Geurts M., and Maloteaux J.M. Down-regulation of neurotensin receptors after ligand-induced internalization in rat primary cultured neurons. Neurochem Int 31 2 (1997) 291-299
35. Izukura M., Evers B.M., Parekh D., Yoshinaga K., Uchida T., Townsend Jr. C.M., et al. Neurotensin augments intestinal regeneration after small bowel resection in rats. Ann Surg 215 5 (1992) 520-526
36. Jennes L., Stumpf W.E., and Kalivas P.W. Neurotensin: topographical distribution in rat brain by immunohistochemistry. J Comp Neural 210 3 (1982) 211-224
37. Kitabgi P., de Nadai F., Rovere C., and Bidard J.N. Biosynthesis, maturation, release, and degradation of neurotensin and neuromedin N. Ann NY Acad Sci 668 (1992) 30-42
38. Lu D., Yang H., Shaw G., and Raizada M.K. Angiotensin II-induced nuclear targeting of the angiotensin type 1 (AT1) receptor in brain neurons. Endocrinology 139 1 (1998) 365-375
39. Martin S., Navarro V., Vincent J.P., and Mazella J. Neurotensin receptor-1 and -3 complex modulates the cellular signaling of neurotensin in the HT29 cell line. Gastroenterology 123 4 (2002) 1135-1143
40. Mashford M.L., Nilsson G., Rokaeus A., and Rosell S. Release of neurotensin-like immunoreactivity (NTLI) from the gut in anaesthetized dogs. Acta Physiol Scand 104 3 (1978) 375-376
41. Mazella J., Chabry J., Leonard K., Kitabgi P., Vincent J.P., and Beaudet A. Internalization of neurotensin in cultured neurons. Ann NY Acad Sci 668 (1992) 356-358
42. Mazella J., Leonard K., Chabry J., Kitabgi P., Vincent J.P., and Beaudet A. Binding and internalization of iodinated neurotensin in neuronal cultures from embryonic mouse brain. Brain Res 564 2 (1991) 249-255
43. Mazella J., Zsurger N., Navarro V., Chabry J., Kaghad M., Caput D., et al. The 100-kDa neurotensin receptor is gp95/sortilin, a non-G-protein-coupled receptor. J Biol Chem 273 41 (1998) 26273-26276
44. Meggiato T., Ferrara C., Tessari G., Plebani M., De Paoli M., Del Favero G., et al. Serum neurotensin in human pancreatic cancer. Tumori 82 6 (1996) 592-595
45. Mendez M., Souaze F., Nagano M., Kelly P.A., Rostene W., and Forgez P. High affinity neurotensin receptor mRNA distribution in rat brain and peripheral tissues. Analysis by quantitative RT-PCR. J Mol Neurosci 9 2 (1997) 93-102
46. Morinville A., Martin S., Lavallee M., Vincent J.P., Beaudet A., and Mazella J. Internalization and trafficking of neurotensin via NTS3 receptors in HT29 cells. Int J Biochem Cell Biol 36 11 (2004) 2153-2168
47. Najimi M., Souaze F., Mendez M., Hermans E., Berbar T., Rostene W., et al. Activation of receptor gene transcription is required to maintain cell sensitization after agonist exposure. Study on neurotensin receptor. J Biol Chem 273 34 (1998) 21634-21641
48. Najimi M., Souaze F., Mendez M., Hermans E., Berbar T., Rostene W., et al. Activation of receptor gene transcription is required to maintain cell sensitization after agonist exposure. Study on neurotensin receptor. J Biol Chem 273 34 (1998) 21634-21641
49. Nguyen H.M., Cahill C.M., McPherson P.S., and Beaudet A. Receptor-mediated internalization of [3H]-neurotensin in synaptosomal preparations from rat neostriatum. Neuropharmacology 42 8 (2002) 1089-1098
50. Nielsen M.S., Jacobsen C., Olivecrona G., Gliemann J., and Petersen C.M. Sortilin/neurotensin receptor-3 binds and mediates degradation of lipoprotein lipase. J Biol Chem 274 13 (1999) 8832-8836
51. Nouel D., Faure M.P., St Pierre J.A., Alonso R., Quirion R., and Beaudet A. Differential binding profile and internalization process of neurotensin via neuronal and glial receptors. J Neurosci 17 5 (1997) 1795-1803
52. Nustede R., Kohler H., Folsch U.R., and Schafmayer A. Plasma concentrations of neurotensin and CCK in patients with chronic pancreatitis with and without enzyme substitution. Pancreas 6 3 (1991) 260-265
53. Oakley R.H., Laporte S.A., Holt J.A., Barak L.S., and Caron M.G. Molecular determinants underlying the formation of stable intracellular G protein-coupled receptor-beta-arrestin complexes after receptor endocytosis. J Biol Chem 276 22 (2001) 19452-19460
54. Oakley R.H., Laporte S.A., Holt J.A., Caron M.G., and Barak L.S. Differential affinities of visual arrestin, beta arresting and beta arrestin2 for G protein-coupled receptors delineate two major classes of receptors. J Biol Chem 275 22 (2000) 17201-17210
55. Omary M.B., and Kagnoff M.F. Identification of nuclear receptors for VIP on a human colonic adenocarcinoma cell line. Science 238 4833 (1987) 1578-1581
56. Petersen C.M., Nielsen M.S., Nykjaer A., Jacobsen L., Tommerup N., Rasmussen H.H., et al. Molecular identification of a novel candidate sorting receptor purified from human brain by receptor-associated protein affinity chromatography. J Biol Chem 272 6 (1997) 3599-3605
57. Pichon M.F., Coquin G., Fauveau C., and Rey A. Serum cholecystokinin and neurotensin during follow-up of pancreas, prostate and medullary thyroid tumors. Anticancer Res 19 2B (1999) 1445-1450
58. Re R.N., Vizard D.L., Brown J., and Bryan S.E. Angiotensin II receptors in chromatin fragments generated by micrococcal nuclease. Biochem Biophys Res Commun 119 1 (1984) 220-227
59. Reinecke M. Neurotensin. Immunohistochemical localization in central and peripheral nervous system and in endocrine cells and its functional role as neurotransmitter and endocrine hormone. Prog Histochem Cytochem 16 1 (1985) 1-172
60. Reubi J.C., Waser B., Friess H., Buchler M., and Laissue J. Neurotensin receptors: a new marker for human ductal pancreatic adenocarcinoma. Gut 42 4 (1998) 546-550
61. Reubi J.C., Waser B., Schaer J.C., and Laissue J.A. Neurotensin receptors in human neoplasms: high incidence in Ewing's sarcomas. Int J Cancer 82 2 (1999) 213-218
62. Sehgal I., Powers S., Huntley B., Powis G., Pittelkow M., and Maihle N.J. Neurotensin is an autocrine trophic factor stimulated by androgen withdrawal in human prostate cancer. Proc Natl Acad Sci USA 91 11 (1994) 4673-4677
63. Souaze F., Ntodou-Thome A., Tran C.Y., Rostene W., and Forgez P. Quantitative RT-PCR: limits and accuracy. Biotechniques 21 2 (1996) 280-285
64. Souaze F., Rostene W., and Forgez P. Neurotensin agonist induces differential regulation of neurotensin receptor mRNA. Identification of distinct transcriptional and post-transcriptional mechanisms. J Biol Chem 272 15 (1997) 10087-10094
65. Souaze F., Viardot-Foucault V., Roullet N., Toy-Miou-Leong M., Gompel A., Bruyneel E., et al. Neurotensin receptor 1 gene activation by the Tcf/{beta}-catenin pathway is an early event in human colonic adenomas. Carcinogenesis 27 4 (2006) 708-716
66. Tanaka K., Masu M., and Nakanishi S. Structure and functional expression of the cloned rat neurotensin receptor. Neuron 4 6 (1990) 847-854
67. Tang S.S., Rogg H., Schumacher R., and Dzau V.J. Characterization of nuclear angiotensin-II-binding sites in rat liver and comparison with plasma membrane receptors. Endocrinology 131 1 (1992) 374-380
68. Theodorsson-Norheim E., Oberg K., Rosell S., and Bostrom H. Neurotensinlike immunoreactivity in plasma and tumor tissue from patients with endocrine tumors of the pancreas and gut. Gastroenterology 85 4 (1983) 881-889
69. Thomas R.P., Hellmich M.R., Townsend Jr. C.M., and Evers B.M. Role of gastrointestinal hormones in the proliferation of normal and neoplastic tissues. Endocr Rev 24 5 (2003) 571-599
70. Toy-Miou-Leong M., Bachelet C.M., Pelaprat D., Rostene W., and Forgez P. NT agonist regulates expression of nuclear high-affinity neurotensin receptors. J Histochem Cytochem 52 3 (2004) 335-345
71. Toy-Miou-Leong M., Cortes C.L., Beaudet A., Rostene W., and Forgez P. Receptor trafficking via the perinuclear recycling compartment accompanied by cell division is necessary for permanent neurotensin cell sensitization and leads to chronic mitogen-activated protein kinase activation. J Biol Chem 279 13 (2004) 12636-12646
72. Turner J.T., James-Kracke M.R., and Camden J.M. Regulation of the neurotensin receptor and intracellular calcium mobilization in HT29 cells. J Pharmacol Exp Ther 253 3 (1990) 1049-1056
73. Vandenbulcke F., Nouel D., Vincent J.P., Mazella J., and Beaudet A. Ligand-induced internalization of neurotensin in transfected COS-7 cells: differential intracellular trafficking of ligand and receptor. J Cell Sci 113 Pt 17 (2000) 2963-2975
74. Vanisberg M.A., Maloteaux J.M., Octave J.N., and Laduron P.M. Rapid agonist-induced decrease of neurotensin receptors from the cell surface in rat cultured neurons. Biochem Pharmacol 42 12 (1991) 2265-2274
75. Ventura C., Maioli M., Pintus G., Posadino A.M., and Tadolini B. Nuclear opioid receptors activate opioid peptide gene transcription in isolated myocardial nuclei. J Biol Chem 273 22 (1998) 13383-13386
76. Wang L., Friess H., Zhu Z., Graber H., Zimmermann A., Korc M., et al. Neurotensin receptor-1 mRNA analysis in normal pancreas and pancreatic disease. Clin Cancer Res 6 2 (2000) 566-571
77. Wood S.M., Wood J.R., Ghatei M.A., Lee Y.C., O'Shaughnessy D., and Bloom S.R. Bombesin, somatostatin and neurotensin-like immunoreactivity in bronchial carcinoma. J Clin Endocrinol Metab 53 6 (1981) 1310-1312