Characterization of maleuric acid derivatives on transgenic human monoclonal antibody due to post-secretional modifications in goat milk

Biomedical Chromatography

Volumn 20, Issue 9, 2006, Pages 843-856

  Santora, Ling C ^a   Stanley, K ^a   Krull, I S ^b   Grant, K ^a  

^a ABBOTT LABORATORIES   (United States)

^b NORTHEASTERN UNIVERSITY   (United States)

Author keywords

Antibody analysis; Antibody variants; Ion exchange HPLC; LCQ; Maleuric acid; Mass spectrometry; Post secretional modifications; Q TOF

Indexed keywords

AMINO ACIDS; DAIRY PRODUCTS; DIGITAL STORAGE; MASS SPECTROMETRY; MONOCLONAL ANTIBODIES; PURIFICATION;

ANTIBODY ANALYSE; ANTIBODY VARIANT; GOAT'S MILK; ION EXCHANGE HPLC; ISOFORMS; LCQ; MALEURIC ACID; POST-SECRETIONAL MODIFICATION; Q-TOF; TRANSGENICS;

ION EXCHANGE;

AMINO ACID DERIVATIVE; LYSINE; MALEURIC ACID DERIVATIVE; SIALIC ACID; TUMOR NECROSIS FACTOR ALPHA ANTIBODY; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; GOAT; HEAVY CHAIN; ION EXCHANGE CHROMATOGRAPHY; LIGHT CHAIN; MAMMARY GLAND; MASS SPECTROMETRY; MILK; MOLECULAR WEIGHT; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PROCESSING; TIME OF FLIGHT MASS SPECTROMETRY; TRANSGENIC ANIMAL;

CAPRA HIRCUS;

EID: 33748929886     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.603     Document Type: Article

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