Hypercholesterolaemia is not associated with early atherosclerotic lesions in primary biliary cirrhosis

Gut

Volumn 55, Issue 12, 2006, Pages 1795-1800

  Allocca, M ^b   Crosignani, A ^b   Gritti, A ^b   Ghilardi, G ^b   Gobatti, D ^b   Caruso, D ^b   Zuin, M ^b   Podda, M ^b   Battezzati, P M ^a,b  

^a SAN PAOLO HOSPITAL   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; ATHEROSCLEROTIC CARDIOVASCULAR DISEASE; CARDIOVASCULAR RISK; CAROTID ARTERY OBSTRUCTION; CONTROLLED STUDY; FEMALE; HUMAN; HYPERCHOLESTEROLEMIA; LIPID ANALYSIS; MAJOR CLINICAL STUDY; MALE; PRIMARY BILIARY CIRRHOSIS; PRIORITY JOURNAL; RADIODIAGNOSIS;

AGE FACTORS; ATHEROSCLEROSIS; CAROTID ARTERIES; CAROTID STENOSIS; CHOLESTEROL; FEMALE; HUMANS; HYPERCHOLESTEROLEMIA; HYPERTENSION; LIVER CIRRHOSIS, BILIARY; MALE; MIDDLE AGED; RISK FACTORS; TUNICA INTIMA;

EID: 33748928370     PISSN: 00175749     EISSN: None     Source Type: Journal    
DOI: 10.1136/gut.2005.079814     Document Type: Article

References (25)

1. Talkwalkar JA, Lindor KD. Primary biliary cirrhosis. Lancet 2003;362:53-61.
2. Selmi C, Invernizzi P, Keefe EB, et al. Epidemiology and pathogenesis of primary biliary cirrhosis. J Clin Gastroenterol 2004;38:264-71.
3. Prince MI, Chetwynd A, Craig WL, et al. Asymptomatic primary biliary cirrhosis: clinical features, prognosis, and symptom progression in a large population based cohort. Gut 2004;53:865-70.
4. Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults. Executive summary of the third report of the National Cholesterol Education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III). JAMA 2001;285:2486-97.
5. Miettinen TA. Lipid absorption, bile acid and cholesterol metabolism in patients with chronic liver disease. Gut 1972;13:682-9.
6. Crippin JS, Lindor KD, Jorgensen R, et al. Hypercholesterolemia and atherosclerosis in primary biliary cirrhosis: what is the risk? Hepatology 1992;15:858-62.
7. Longo M, Crosignani A, Battezzati PM, et al. Hyperlipidaemic state and cardiovascular risk in primary biliary cirrhosis. Gut 2002;51:265-9.
8. Van Dam GM, Gips CH. Primary biliary cirrhosis in the Netherlands. Scand J Gastroenterol 1997;32:77-83.
9. Mannami T, Konishi M, Baba S, et al. Prevalence of asymptomatic carotid atherosclerotic lesions detected by high-resolution ultrasonography and its relation to cardiovascular risk factors in the general population of a Japanese city: the Suita study city. Stroke 1997;28:518-25.
10. Burke GL, Evans GW, Riley WA, et al. Arterial wall thickness is associated with prevalent cardiovascular disease in middle-aged adults: the Atherosclerosis Risk in Communities (ARIC) Study. Stroke 1995;26:386-91.
11. O'Leary DH, Polak JF, Kronmal RA, et al. Carotid-artery intima and media thickness as a risk factor for myocardial infarction and stroke in older adults. N Engl J Med 1999;340:14-22.
12. Hodis HN, Mack WJ, LaBree L, et al. The role of carotid arterial intima-media thickness in predicting clinical coronary events. Ann Intern Med 1998;128:262-9.
13. Kaplan M. Medical progress: primary biliary cirrhosis. N Engl J Med 1996;335:1570-80.
14. De Fabiani E, Caruso D, Cavaleri M, et al. Cholesta-5,7,9(11)-trien 3bela-ol found in plasma of patients with Smith-Lemli-Opitz syndrome indicates formation of sterol hydroperoxide. J Lipid Res 1996;37:2280-7.
15. Montauban van Swijndregt AO, De Lange EE, De Groot E, et al. An in vivo evaluation of the reproducibility of intima-media thickness measurements of the carotid artery segments using B-mode ultrasound. Ultrasound Med Biol 1999;25:323-30.
16. Kagawa R, Moritake K, Shima T, et al. Validity of B-mode ultrasonographic findings in patients undergoing carotid endarterectomy in comparison with angiographic and clinicopathologic features. Stroke 1996;27:700-5.
17. Carpenter JP, Lexa FJ, Davis JT. Determination of duplex Doppler ultrasound criteria appropriate to the North American Symptomatic Carotid Endarterectomy Trial. Stroke 1996;27:695-9.
18. Williamson DF, Parker RA, Kendrick JS. The box plot: a simple visual method to interpret data. Ann Intern Med 1989;110:916-21.
19. Agorastos J, Fox C, Harry DS, et al. Lecitin-cholesterol acyltransferase and the lipoprotein abnormalities of obstructive jaundice. Clin Sci Mal Med 1978;54:369-79.
20. Sörös P, Böttcher J, Maschek H, et al. Lipoprotein-X in patients with cirrhosis: its relationship to cholestasis and hypercholesterolemia. Hepatology 1998;28:1199-205.
21. Rader DJ, Puré E. Lipoprotein, macrophage function, and atherosclerosis: beyond the foam cell? Cell Metab 2005;1:223-30.
22. Balan V, Dickson ER, Jorgensen RA, et al. Effects of ursodeoxycholic acid on serum lipids of patients with primary biliary cirrhosis. Mayo Clin Proc 1994;69:923-9.
23. Poupon RE, Oguerram K, Chrétien Y, et al. Cholesterol-lowering effect of ursodeoxycholic acid in patients with primary biliary cirrhosis. Hepatology 1993;17:577-82.
24. Miettinen TA, Färkkilä M, Vuoristo M, et al. Serum cholestanol, cholesterol precursors, and plant sterols during placebo-controlled treatment of primary biliary cirrhosis with ursodeoxycholic acid or colchicine. Hepatology 1995;21:1261-8.
25. Del Puppo M, Galli-Kienle M, Crosignani A, et al. Cholesterol metabolism in primary biliary cirrhosis during simvastatin and UDCA administration. J Lipid Res 2001;42:437-41.