The effect of human growth hormone on superoxide dismutase activity, glutathione and malondialdehyde levels of hypoxic-ischemic newborn rat brain

Biology of the Neonate

Volumn 90, Issue 3, 2006, Pages 168-173

  Yapicioǧlu, Hacer ^a   Satar, Mehmet ^a   Canacankatan, Necmiye ^a   Tutak, Ercan ^a   Sertdemir, Yaşar ^a   Antmen, Efsun ^a   Narli, Nejat ^a  

^a CUKUROVA UNIVERSITY   (Turkey)

Author keywords

Brain; Glutathione; Growth hormone; Hypoxia ischemia; Malondialdehyde; Newborn; Rat; Superoxide dismutase

Indexed keywords

GLUTATHIONE; HUMAN GROWTH HORMONE; MALONALDEHYDE; SUPEROXIDE DISMUTASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN DISEASE; BRAIN ISCHEMIA; BRAIN LEVEL; BRAIN STEM; CAROTID ARTERY LIGATION; CEREBELLUM; CONTROLLED STUDY; HISTOPATHOLOGY; HORMONAL REGULATION; HORMONE RESPONSE; HYPOXEMIA; LEFT HEMISPHERE; LIPID PEROXIDATION; NEUROCHEMISTRY; NEUROPATHOLOGY; NEUROPROTECTION; NEUROTOXICITY; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN DETERMINATION; RANDOMIZATION; RAT; RIGHT HEMISPHERE;

ANIMALS; ANIMALS, NEWBORN; BRAIN; BRAIN CHEMISTRY; BRAIN STEM; CAROTID ARTERY, COMMON; CEREBELLUM; GLUTATHIONE; HUMAN GROWTH HORMONE; HUMANS; HYPOXIA-ISCHEMIA, BRAIN; LIGATION; LIPID PEROXIDATION; MALONDIALDEHYDE; RATS; SUPEROXIDE DISMUTASE;

EID: 33748911192     PISSN: 00063126     EISSN: None     Source Type: Journal    
DOI: 10.1159/000092680     Document Type: Article

References (38)

1. de Zwart LL, Meerman JHN, Commandeur JNM, et al: Biomarkers of free radical damage applications in experimental animals and in humans. Free Radic Biol Med 1999;26:202-226.
2. Villa RF, Gorini A: Pharmacology of lazaroids and brain energy metabolism: a review. Pharmacol Rev 1997;49:99-136.
3. Lobie PE, Garcia-Aragon J, Lincoln DT, et al: Localization and ontogeny of growth hormone receptor gene expression in the central nervous system. Dev Brain Res 1993;74:225-233.
4. Scheepens A, Williams CE, Breier BH, et al: A role for the somatotropic axis in neural development, injury and disease. J Pediatr Endocrinol Metab 2000;13(suppl):1483-1491.
5. Gustafson K, Hagberg H, Bengtsson B, et al: Possible protective role of growth hormone in hypoxia-ischemia in neonatal rats. Pediatr Res 1999;45:318-323.
6. Scheepens S, Sirimanne ES, Breier BH, et al: Growth hormone as a rescue factor during recovery from CNS injury. Neuroscience 2001;104:677-687.
7. Shin DH, Lee E, Kim JW, et al: Protective effect of growth hormone on neuronal apoptosis after hypoxia-ischemia in the neonatal rat brain. Neurosci Lett 2004;354:64-68.
8. Brown-Borg HM, Bode AM, Barke A: Antioxidative mechanisms and plasma growth hormone levels. Potential relationship in the aging process. Endocrine 1999;11:41-48.
9. Hauck SJ, Bartke A: Effects of growth hormone on hypothalamic catalase and Cu/Zn superoxide dismutase. Free Radic Biol Med 2000;28:970-978.
10. Youn YK, Suh GJ, Jung SE, et al: Recombinant human growth hormone decreases lung and liver lipid peroxidation and increases antioxidant activity after thermal injury in rats. J Burn Care Rehabil 1998;19:542-548.
11. Smith JC, Lang D, McEneny J, et al: Effects of GH on lipid peroxidation and neutrophil superoxide anion-generating capacity in hypopitutary adults with GH deficiency. Clin Endocrinol (Oxf) 2002;56:449-455.
12. Levine S: Anoxic-ischemic encephalopathy in rats: Am J Pathol 1960;36:1-17.
13. Towfighi J, Zec N, Yager J, et al: Temporal evolution of neuropathologic changes in an immature rat model of cerebral hypoxia-ischemia. A light microscopic study. Acta Neuropathol 1995;90:375-386.
14. Lowry OH, Rosenbrough NJ, Farr AL, et al: Protein measurement with the folin phenol reagent. J Biol Chem 1951;193:265-275.
15. Beutker E: Red Cell Metabolism, A Manuel of Biochemical Methods. New York, Grune & Stratton, 1975, p 112.
16. McCord JM, Fridovich I: Superoxide dismutase, an enzymatic function for erythrocuprein (hemocuprein). J Biol Chem 1969;244:6049-6055.
17. Okhawa H, Ohishi N, Yagi K: Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 1979;95:352-358.
18. Bagenholm R, Nilsson UA, Kjellmer I: Formation of free radicals in hypoxic ischemic brain damage in the neonatal rat, assessed by an endogenous spin trap and lipid peroxidation. Brain Res 1997;773:132-138.
19. Lazzarino G, Vagnozzi R, Tavazzi B, et al: MDA, oxypurines, and nucleosides relate to reperfusion in short-term incomplete cerebral ischemia in the rat. Free Radic Biol Med 1992;12:489-498.
20. Watson BD, Busto R, Goldberg WJ, et al: Lipid peroxidation in vivo induced by reversible global ischemia in rat brain. J Neurochem 1984;42:268-274.
21. Matsuo Y, Kihara T, Ikeda M, et al: Role of neutrophils in radical production during cerebral ischemia and reperfusion of the rat brain. J Cereb Blood Flow Metab 1995;15:941-947.
22. Fellman V, Raivio KO: Reperfusion injury as the mechanism of brain damage after perinatal asphyxia. Pediatr Res 1997;41:599-606.
23. Huguet F, Guerraoui A, Barrier L, et al: Changes in excitatory amino acid levels and tissue energy metabolites of neonate rat brain after hypoxia and hypoxia-ischemia. Neurosci Lett 1998;240:102-106.
24. Armstead XM, Mirro R, Busija DW, et al: Post-ischemic generation of superoxide anion by newborn pig brain. Am J Physiol 1988;225:H401-H403.
25. Ichord RN, Kirsch JR, Helfaer MA, et al: Age-related differences in recovery of blood flow and metabolism after cerebral ischemia in swine. Stroke 1991;22:626-634.
26. Noguchi T: Effects of growth hormone on cerebral development: Morphological studies. Horm Res 1996;45:5-17.
27. Almazon G, Honegger P, Matthieu JM, et al: Epidermal growth factor and bovine growth hormone stimulate differentiation and myelination of brain cell aggregates in culture. Brain Res 1985;353:257-264.
28. Hynes MA, van Wyk JJ, Brooks PJ, et al: Growth hormone dependence of somatomedin-C/insulin-like growth factor-I and insulin-like growth factor-II messenger ribonucleic acids. Mol Endocrinol 1987;1:233-242.
29. Goh EL, Pircher TJ, Lobie PE: Growth hormone promotion of tubulin polymerization stabilizes the microtubule network and protects against colchicine- induced apoptosis. Endocrinology 1998;139:4364-4372.
30. Haeffner A, Deas O, Mollereau B, et al: Growth hormone prevents human monocytic cells from Fas-mediated apoptosis by up-regulating Bcl-2 expression. Eur J Immunol 1999;29:334-344.
31. Matsuda T, Sato H, Inoue T, et al: Growth hormone inhibits apoptosis and up-regulates reactive oxygen intermediates production by human polymorphonuclear neutrophils. J Parenter Enteral Nutr 1998;22:368-374.
32. Scheepens A, Sirimanne E, Beilharz E, et al: Alterations in the neural growth hormone axis following hypoxic-ischemic brain injury. Mol Brain Res 1999;68:88-100.
33. Johansson J-O, Larsson G, Andersson M, et al: Treatment of growth hormone- deficient adults with recombinant human growth hormone increases the concentration of growth hormone in the cerebrospinal fluid and affects neurotransmitters. Neuroendocrinology 1995;61:57-66.
34. Mustafa A, Sharma HS, Olsson Y, et al: Vascular permeability to growth hormone in the rat central nervous system after focal spinal cord injury: influence of a new anti-oxidant H 290:51 and age. Neurosci Res 1995;23:185-194.
35. Wiedermann CJ, Reinisch N, Braunsteiner H: Stimulation of monocyte chemotaxis by human growth hormone and deactivation by somatostatin. Blood 1993;82:954-960.
36. Steinbrecher UP: Role of superoxide in endothelial-cell modification of low-density lipoproteins. Biochim Biochys Acta 1998;959:20-30.
37. Scaccini C, Jialal L: LDL modification by activated polymorphonuclear leukocytes: a cellular model of mild oxidative stress. Free Radic Biol Med 1993;16:49-55.
38. Homi HM, Freitas JJ, Curi R, et al: Changes in superoxide dismutase and catalase activities of rat brain regions during early global transient ischemia/reperfusion. Neurosci Lett 2002;333:37-40.