Recombinant human growth hormone decreases lung and liver tissue lipid peroxidation and increases antioxidant activity after thermal injury in rats

Journal of Burn Care and Rehabilitation

Volumn 19, Issue 6, 1998, Pages 542-548

  Youn, Yeo Kyu ^a   Suh, Gil Joon ^a   Jung, Sung Eun ^b   Oh, Seung Keun ^c   Demling, Robert ^d  

^a Department of Surgery ^*  (South Korea)

^b Seoul National University College of Medicine   (South Korea)

^c HARVARD MEDICAL SCHOOL   (United States)

^d BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANT; CATALASE; GLUTATHIONE; HUMAN GROWTH HORMONE; MALONALDEHYDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD VESSEL PERMEABILITY; CELL MEMBRANE PERMEABILITY; CELL SURVIVAL; CONTROLLED STUDY; ENZYME ACTIVITY; LIPID PEROXIDATION; LIVER FUNCTION; LUNG FUNCTION; NONHUMAN; OXIDATIVE STRESS; RAT; THERMAL INJURY; WOUND HEALING;

EID: 0031796470     PISSN: 02738481     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004630-199811000-00015     Document Type: Article

References (30)

1. Nguyen TT, Cox CS, Traber DL, Gasser H, Redl H, Schlag G, et ai. Free radical activity and loss of plasma antioxidants, vitamin E, and sulfhydryl groups in patients with burns: the 1993 Mover Award. J Burn Care Rehabil 1993;14:602-9.
2. Till GO, Hatherill JK, Tourtellotte WW, Lutz MJ, Ward PA. Lipid pcroxidation and acute lung injury after thermal trauma to skin: evidence of a role for hydroxyl radical. Am J Pathol 1985;! 19:376-84.
3. Demling R, LaLonde C, Knox J, Youn YK, Zhu D, Daryani R. Fluid resuscitation with deferoxamine prevents systemic burn-induced oxidant injury. J Trauma 1991;31:538-43.
4. Demling RH, LaLonde C. Identification and modifications of the pulmonary and systemic inflammatory and biochemical changes caused by a skin burn. J Trauma 1990;30:S57-62.
5. Oldham KT, Guice KS, Till GO, Ward PA. Activation of complement by hydroxyl radical in thermal injury. Surgery 1988;104:272-9.
6. LaLonde C, Nayak U, Hennigan J, Demling R. Antioxidants prevent the cellular deficit produced in response to burn injury. J Burn Care Rehabil 1996;17:379-83.
7. Till GO, Friedl HP, Ward PA. Antioxidant treatment in experimental thermal injury. Adv Exp Med Biol 1990; 264:543-9.
8. Matsuda T, Tanaka H, Shimazaki S, Matsuda H, Abcarian H, Reyes H, et al. High-dose vitamin C therapy for extensive deep dermal burns. Burns 1992;18:127-31.
9. Gatzen C, Scheltinga MR, Kimbrough TD, Jacobs DO, Wilmore DW. Growth hormone attenuates the abnormal distribution of body water in critically ill surgical patients. Surgery 1992;112:181-85.
10. Gottardis M, Benzer A, Koller W, Luger TJ, Pühringer F, Hack! J. Improvement of septic syndrome after administration of recombinant human growth hormone. J Trauma 1991;31:81-6.
11. Ziegler T. Growth hormone administration during nutritional support: what is to be gained? In: Wilmore D, editor. New horizons: frontiers in critical care nutrition. Fullerton (CA): Society of Critical Care Medicine; 1994. p. 244-56.
12. Byrne TA, Morrissey TB, Gatzen C, Benfell K, Nattakom TV, Scheltinga MR, et al. Anabolic therapy with growth hormone accelerates gain in lean tissue in surgical patients requiring nutritional rehabilitation. Ann Surg 1993;218:400-18.
13. Knox J, Demling R, Wilmore D, Sarraf P, Santos A. Increased survival after major thermal injury: the effect of growth hormone therapy in adults. J Trauma 1995;39:526-32.
14. Hcrndon DN, Barrow RE, Kunkel KR, Broemeling L, Rutan RL. Effect of recombinant human growth hormone on donor site healing in severely burned children. Am Surg 1990;212:424-9.
15. Reichard S, Bailey N, Galvin M. Alterations in tissue glutathione levels following traumatic shock. Adv Shock Res 1981;5:37-45.
16. Meister A, Anderson M. Glutathione. Annu Rev Biochem 1983;52:711-50.
17. Demling R, Youn Y, LaLonde C. The effect of acute nonbacterial dependent peritonitis on lung and liver oxidant stress and antioxidant activity. Surgery 1993;114:571-8.
18. Matthews L. Molecular biology of growth hormone receptors. Trends Endocrinol Metab 1991;2:176-86.
19. Kostyo J, Reagan C. The biology of growth hormone. Pharmacol Ther 1976;2:591-604.
20. Ikegami K, LaLonde C, Youn YK. Comparison of plasma reduced glutathione and oxidized glutathione with lung and liver tissue oxidant and antioxidant activity during acute inflammation. Shock 1994;1:307-12.
21. Kono Y, Fridovich I. Superoxide radical inhibits catalase. J Biol Chcm 1982;257:5751-4.
22. Perry M. Catalase: an old enzyme with a new role. Can J Biochem Cell Biol 1984;62:1006-14.
23. Walker H, Mason A. A standard animal burn. J Trauma 1968;8:1049-51.
24. Ohkawa H, Ohishi N, Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 1979;85:351-8.
25. Griffith OW. Determination of glutathione and glutathione sulfide using glutathione reductase and 2-vinylpyridine. Anal Biochem 1980;106:207-12.
26. Beers RF, Sizer IW. A spectrophotomctric method for measuring the breakdown of hydrogen peroxide by catalase. J Biol Chem 1952;195:133-9.
27. Sies H. Oxidative stress: from basic research to clinical application. Am J Med 1991;91:31-41.
28. Jahoor F, Desai M, Herndon D. Dynamics of the protein metabolic response to burn injury. Metabolism 1988; 37:330-6.
29. Demling R, DeSanti L. Use of anticatabolic agents for burns. Curr Opin Crit Care 1996;2:482-91.
30. Woolliscroft JO, Prasad JK, Thomson P, Till GO, Fox IH. Metabolic alterations in burn patients: detection of adenine triphosphate degradation products and lipid peroxides. Burns 1990;16:92-6.