Activated thrombelastogram in neonates and infants with complex congenital heart disease in comparison with healthy children

British Journal of Anaesthesia

Volumn 97, Issue 4, 2006, Pages 545-552

  Haizinger, Betina ^a   Gombotz, H ^a   Rehak, P ^b   Geiselseder, G ^a   Mair, R ^a  

^a KEPLER UNIVERSITY HOSPITAL   (Austria)

^b MEDICAL UNIVERSITY OF GRAZ   (Austria)

Author keywords

Anaesthesia, paediatric; Blood, coagulation; Infants; Measurement techniques, Thrombelastograph ; Neonates

Indexed keywords

ANALYSIS OF VARIANCE; ARTICLE; BLOOD CLOTTING TIME; BLOOD SAMPLING; CHILD; CONGENITAL HEART DISEASE; CONTROLLED STUDY; FEMALE; FIBRINOLYSIS; HEMOSTASIS; HUMAN; HYPERCOAGULABILITY; INFANT; MAJOR CLINICAL STUDY; MALE; MINOR SURGERY; NEWBORN; PREOPERATIVE EVALUATION; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE; THROMBOELASTOGRAPHY;

EID: 33748863911     PISSN: 00070912     EISSN: 14716771     Source Type: Journal    
DOI: 10.1093/bja/ael206     Document Type: Article

References (22)

1. Miller BE, Guzzetta NA, Tosone SR, Levy JH. Rapid evaluation of coagulopathies after cardiopulmonary bypass in children using modified thromboelastography. Anesth Analg 2000; 90: 1324-30
2. Tempe DK, Virmani S. Coagulation abnormalities in patients with cyanotic congenital heart disease. J Cardiothorac Vasc Anesth 2002; 16: 752-65
3. Lang T, Toller W, Gutl M, et al. Different effects of abciximab and cytochalasin D on clot strength in thrombelastography. J Thromb Haemost 2004; 2: 147-53
4. Miller BE, Mochizuki T, Levy JH, et al. Predicting and treating coagulopathies after cardiopulmonary bypass in children. Anesth Analg 1997; 85: 1196-202
5. Martin P, Horkay F, Rajah SM, Walker DR. Monitoring of coagulation status using thrombelastography during paediatric open heart surgery. Int J Clin Monit Comput 1991; 8: 183-7
6. Cammerer U, Dietrich W, Rampf T, Braun SL, Richter JA. The predictive value of modified computerized thromboelastography and platelet function analysis for postoperative blood loss in routine cardiac surgery. Anesth Analg 2003; 96: 51-7, table of contents
7. Royston D, Von KS. Reduced haemostatic factor transfusion using heparinase-modified thrombelastography during cardiopulmonary bypass. Br J Anaesth 2001; 86: 575-8
8. Shore-Lesserson L, Manspeizer HE, DePerio M, Francis S, Vela-Cantos F, Ergin MA. Thromboelastography-guided transfusion algorithm reduces transfusions in complex cardiac surgery. Anesth Analg 1999; 88: 312-19
9. Miller BE, Bailey JM, Mancuso TJ, et al. Functional maturity of the coagulation system in children: An evaluation using thrombelastography. Anesth Analg 1997; 84: 745-8
10. Miller BE, Guzzetta NA, Tosone SR, et al. Tissue factor-activated thromboelastograms in children undergoing cardiac surgery: Baseline values and comparisons. Anesth Analg 2003; 97: 1289-93
11. Kettner SC, Pollak A, Zimpfer M, et al. Heparinase-modified thrombelastography in term and preterm neonates. Anesth Analg 2004; 98: 1650
12. Burghardt WR, Goldstick TK, Leneschmidt J, Kempka K. Nonlinear viscoelasticity and the thrombelastograph: 1. Studies on bovine plasma clots. Biorheology 1995; 32: 621-30
13. Camenzind V, Bombeli T, Seifert B, et al. Citrate storage affects Thrombelastograph analysis. Anesthesiology 2000; 92: 1242-9
14. Vig S, Chitolie A, Bevan DH, Halliday A, Dormandy J. Thromboelastography: A reliable test? Blood Coagul Fibrinolysis 2001; 12: 555-61
15. Andrew M. The relevance of developmental hemostasis to hemorrhagic disorders of newborns. Semin Perinatol 1997; 21: 70-85
16. Ichinose F, Uezono S, Muto R, et al. Platelet hyporeactivity in young infants during cardiopulmonary bypass. Anesth Analg 1999; 88: 258-62
17. Koga T, Az-ma T, Yuge O. Prostaglandin E1 at clinically relevant concentrations inhibits aggregation of platelets under synergic interaction with endothelial cells. Acta Anaesthesiol Scand 2002; 46: 987-93
18. Williams GD, Bratton SL, Riley EC, Ramamoorthy C. Coagulation tests during cardiopulmonary bypass correlate with blood loss in children undergoing cardiac surgery. J Cardiothorac Vasc Anesth 1999; 13: 398-404
19. Tuman KJ, McCarthy RJ, Djuric M, Rizzo V, Ivankovich AD. Evaluation of coagulation during cardiopulmonary bypass with a heparinase-modified thromboelastographic assay. J Cardiothorac Vasc Anesth 1994; 8: 144-9
20. Mittermayr M, Margreiter J, Velik-Salchner C, et al. Effects of protamine and heparin can be detected and easily differentiated by modified thrombelastography (Rotem): An in vitro study. Br J Anaesth 2005; 95: 310-16
21. Nielsen VG, Cohen BM, Cohen E. Effects of coagulation factor deficiency on plasma coagulation kinetics determined via thrombelastography: critical roles of fibrinogen and factors II, VII, X and XII. Acta Anaesthesiol Scand 2005; 49: 222-31
22. Barthels M, von Depka M. Das Gerinnungskompendium. Stuttgart: Georg Thieme Verlag, 2003