Platelet hyporeactivity in young infants during cardiopulmonary bypass

Anesthesia and Analgesia

Volumn 88, Issue 2, 1999, Pages 258-262

  Ichinose, Fumito ^a,c   Uezono, Shoichi ^a   Muto, Rika ^b   Uchida, Haruo ^b   Hatori, Fumimaro ^b   Terui, Katsuo ^a   Niimi, Yoshinari ^a   Goto, Takahisa ^a   Nakata, Yoshinori ^a   Morita, Shigeho ^a  

^a TEIKYO UNIVERSITY CHIBA MEDICAL CENTER   (Japan)

^b CHIBA CHILDREN'S HOSPITAL   (Japan)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOPROTEIN IB; PADGEM PROTEIN;

ARTICLE; CARDIOPULMONARY BYPASS; CLINICAL ARTICLE; CONGENITAL HEART DISEASE; CONTROLLED STUDY; FLOW CYTOMETRY; HUMAN; INFANT; NEWBORN; PRIORITY JOURNAL; RECEPTOR DENSITY; THROMBOCYTE; THROMBOCYTE ACTIVATION;

AGE FACTORS; ANALYSIS OF VARIANCE; BLOOD PLATELETS; CARDIOPULMONARY BYPASS; CHILD; CHILD, PRESCHOOL; FLOW CYTOMETRY; HEART DEFECTS, CONGENITAL; HUMANS; INFANT; INFANT, NEWBORN; P-SELECTIN; PLATELET ACTIVATION; PLATELET ADHESIVENESS; PLATELET GLYCOPROTEIN GPIB-IX COMPLEX; PLATELET MEMBRANE GLYCOPROTEINS; POSTOPERATIVE HEMORRHAGE; RECEPTORS, ANTIGEN, B-CELL; RECEPTORS, CELL SURFACE; TIME FACTORS; VON WILLEBRAND FACTOR;

EID: 0032954238     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000539-199902000-00006     Document Type: Article

References (27)

1. Kern FH, Morana NJ, Sears JJ, Hickey PR. Coagulation defects in neonates during cardiopulmonary bypass. Ann Thorac Surg 1992;54:541-6.
2. Boldt J, Knothe C, Zickmann B, et al. Aprotinin in pediatric cardiac operations: platelet function, blood loss, and use of homologous blood. Ann Thorac Surg 1993;55:1460-6.
3. Miller BE, Mochizuki T, Levy JH, et al. Predicting and treating coagulopathies after cardiopulmonary bypass in children. Anesth Analg 1997;85:1196-202.
4. Greeley WJ, Cardiac surgery and postoperative management. Crit Care Med 1993;21:S329-30.
5. Petaja J, Lundstrom U, Leijala M, et al. Bleeding and use of blood products after heart operations in infants. J Thorac Cardiovasc Surg 1995;109:524-9.
6. Harker LA. Bleeding after cardiopulmonary bypass [editorial]. N Engl J Med 1986;314:1446-8.
7. Woodman RC, Harker LA. Bleeding complications associated with cardiopulmonary bypass. Blood 1990;76:1680-97.
8. Kestin AS, Valeri CR, Khuri SF, et al. The platelet function defect of cardiopulmonary bypass. Blood 1993;82:107-17.
9. Rinder CS, Gaal D, Student LA, Smith BR. Platelet-leukocyte activation and modulation of adhesion receptors in pediatric patients with congenital heart disease undergoing cardiopulmonary bypass. J Thorac Cardiovasc Surg 1994;107:280-8.
10. Abrams CS, Ellison N, Budzynski AZ, Shattil SJ. Direct detection of activated platelets and platelet-derived microparticles in humans. Blood 1990;75:128-38.
11. Kondo C, Tanaka K, Takagi K, et al. Platelet dysfunction during cardiopulmonary bypass surgery: with special reference to platelet membrane glycoproteins. ASAIO J 1993;39:M550-3.
12. Huang H, Ding W, Su Z, Zhang W. Mechanism of the preserving effect of aprotinin on platelet function and its use in cardiac surgery. J Thorac Cardiovasc Surg 1993;106:11-8.
13. Primack C, Walenga JM, Koza MJ, et al. Aprotinin modulation of platelet activation in patients undergoing cardiopulmonary bypass operations. Ann Thorac Surg 1996;61:1188-93.
14. Plotz FB, Van Oeveren W, Aloe LS, et al. Prophylactic administration of tranexamic acid preserves platelet numbers during extracorporeal circulation in rabbits. ASAIO Trans 1991;37: M416-7.
15. Kuhne T, Imbach P. Neonatal platelet physiology and pathophysiology. Eur J Pediatr 1998;157:87-94.
16. Michelson AD. Flow cytometry: a clinical test of platelet function. Blood 1996;87:4925-36.
17. Shattil SJ, Cunningham M, Hoxie JA. Detection of activated platelets in whole blood using activation-dependent monoclonal antibodies and flow cytometry. Blood 1987;70:307-15.
18. Rinder CS, Bohnert J, Rinder HM, et al. Platelet activation and aggregation during cardiopulmonary bypass. Anesthesiology 1991;75:388-93.
19. Arad ID, Alpan G, Sznajderman SD, Eldor A. The mean platelet volume (MPV) in the neonatal period. Am J Perinatol 1986;3: 1-3.
20. Kipper SL, Sieger L. Whole blood platelet volumes in newborn infants. J Pediatr 1982;101:763-6.
21. Saving K, Aldag J, Jennings D, et al. Electron microscopic characterization of neonatal platelet ultrastructure: effects of sampling techniques. Thromb Res 1991;61:65-80.
22. Saving KL, Jennings DE, Aldag JC, Caughey RC. Platelet ultrastructure of high-risk premature infants. Thromb Res 1994;73: 371-84.
23. Rajasekhar D, Kestin AS, Bednarek FJ, et al. Neonatal platelets are less reactive than adult platelets to physiological agonists in whole blood. Thromb Haemost 1994;72:957-63.
24. Ekert H, Sheers M. Preoperative and postoperative platelet function in cyanotic congenital heart disease. J Thorac Cardiovasc Surg 1974;67:184-90.
25. Suarez CR, Menendez CE, Griffin AJ, et al. Cyanotic congenital heart disease in children: hemostatic disorders and relevance of molecular markers of hemostasis. Semin Thromb Hemost 1984; 10:285-9.
26. Rinder CS, Bonan JL, Rinder HM, et al. Cardiopulmonary bypass induces leukocyte-platelet adhesion. Blood 1992;79:1201-5.
27. Michelson AD, Barnard MR, Hechtman HB, et al. In vivo tracking of platelets: circulating degranulated platelets rapidly lose surface P-selectin but continue to circulate and function. Proc Natl Acad Sci USA 1996;93:11877-82.