Structural and functional characterization of the conserved salt bridge in mammalian paneth cell α-defensins: Solution structures of mouse cryptdin-4 and (E15D)-cryptdin-4

Journal of Biological Chemistry

Volumn 281, Issue 38, 2006, Pages 28068-28078

  Rosengren, K Johan ^a,b   Daly, Norelle L ^b,e   Fornander, Liselotte M ^a   Jönsson, Linda M H ^a   Shirafuji, Yoshinori ^c   Qu, Xiaoqing ^c   Vogel, Hans J ^d   Ouellette, Andre J ^c   Craik, David J ^b  

^a LINNAEUS UNIVERSITY   (Sweden)

^b UNIVERSITY OF QUEENSLAND   (Australia)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF CALGARY   (Canada)

^e NATIONAL HEALTH AND MEDICAL RESEARCH COUNCIL   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERICIDAL ACTIVITY; IMMUNITY; MUTANTS; PROTEOLYTIC DEGRADATION;

AMINO ACIDS; BIOCHEMISTRY; IMMUNOLOGY; MUTAGENS; SALTS;

ANIMAL CELL CULTURE;

ALPHA DEFENSIN; ARGININE; GLUTAMIC ACID; MATRILYSIN; MUTANT PROTEIN; PROTEIN CRP4; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BACTERICIDAL ACTIVITY; CONTROLLED STUDY; INNATE IMMUNITY; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PANETH CELL; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN STRUCTURE;

ALPHA-DEFENSINS; AMINO ACID SEQUENCE; ANIMALS; ANTI-INFECTIVE AGENTS; HUMANS; HYDROGEN-ION CONCENTRATION; MAGNETIC RESONANCE SPECTROSCOPY; MATRIX METALLOPROTEINASE 7; MICE; MOLECULAR SEQUENCE DATA; MUTATION; RABBITS; SOLUTIONS; STRUCTURE-ACTIVITY RELATIONSHIP; TEMPERATURE;

MAMMALIA;

EID: 33748807728     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M604992200     Document Type: Article

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