메뉴 건너뛰기




Volumn 8, Issue D, 2006, Pages

How does pure heart rate lowering impact on cardiac tolerability?

Author keywords

Cardiac electrophysiology; Cardiac tolerability; Heart rate; If inhibition; Ivabradine; Myocardial contractility; QT interval; Sinus bradycardia

Indexed keywords

AMLODIPINE; ANTIANGINA PECTORIS AGENT; ATENOLOL; IVABRADINE;

EID: 33748805263     PISSN: 1520765X     EISSN: None     Source Type: Journal    
DOI: 10.1093/eurheartj/sul019     Document Type: Review
Times cited : (8)

References (25)
  • 1
    • 27944464487 scopus 로고    scopus 로고
    • If at first you don't succeed try... a new target in the treatment of angina
    • Saha M, Marber MS. If at first you don't succeed try ... a new target in the treatment of angina. Eur Heart J 2005;26:2482-2483.
    • (2005) Eur Heart J , vol.26 , pp. 2482-2483
    • Saha, M.1    Marber, M.S.2
  • 2
    • 0003443998 scopus 로고    scopus 로고
    • European Medicines Agency
    • Summary of Product Characteristics. Procoralan. European Medicines Agency. http://www.emeaeuint/humandocs/humans/epar/procoralan/procoralan.htm (2005).
    • (2005) Summary of Product Characteristics. Procoralan
  • 3
    • 0018387132 scopus 로고
    • How does adrenaline accelerate the heart?
    • Brown HF, DiFrancesco D, Noble SJ. How does adrenaline accelerate the heart? Nature 1979;280:235-236.
    • (1979) Nature , vol.280 , pp. 235-236
    • Brown, H.F.1    DiFrancesco, D.2    Noble, S.J.3
  • 4
    • 20444383848 scopus 로고    scopus 로고
    • Physiology and pharmacology of the cardiac pacemaker ('funny') current
    • Baruscotti M, Bucchi A, DiFrancesco D. Physiology and pharmacology of the cardiac pacemaker ('funny') current. Pharmacol Ther 2005;107:59-79.
    • (2005) Pharmacol Ther , vol.107 , pp. 59-79
    • Baruscotti, M.1    Bucchi, A.2    DiFrancesco, D.3
  • 5
    • 0031008981 scopus 로고    scopus 로고
    • Effects of zatebradine (ULFS 49 CL), a sinus node inhibitor, on heart rate and exercise duration in chronic stable angina pectoris
    • Zatebradine Investigators
    • Glasser SP, Michie DD, Thadani U, Baiker WM. Effects of zatebradine (ULFS 49 CL), a sinus node inhibitor, on heart rate and exercise duration in chronic stable angina pectoris. Zatebradine Investigators. Am J Cardiol 1997;79:1401-1405.
    • (1997) Am J Cardiol , vol.79 , pp. 1401-1405
    • Glasser, S.P.1    Michie, D.D.2    Thadani, U.3    Baiker, W.M.4
  • 6
    • 0029744373 scopus 로고    scopus 로고
    • Mode of action of bradycardic agent, S 16257, on ionic currents of rabbit sinoatrial node cells
    • Bois P, Bescond J, Renaudon B, Lenfant J. Mode of action of bradycardic agent, S 16257, on ionic currents of rabbit sinoatrial node cells. Br J Pharmacol 1996;118:1051-1057.
    • (1996) Br J Pharmacol , vol.118 , pp. 1051-1057
    • Bois, P.1    Bescond, J.2    Renaudon, B.3    Lenfant, J.4
  • 7
    • 0037448788 scopus 로고    scopus 로고
    • Antianginal and antiischemic effects of ivabradine, an I(f) inhibitor, in stable angina: A randomized, double-blind, multicentered, placebo-controlled trial
    • Borer JS, Fox K, Jaillon P, Lerebours G. Antianginal and antiischemic effects of ivabradine, an I(f) inhibitor, in stable angina: a randomized, double-blind, multicentered, placebo-controlled trial. Circulation 2003;107:817-823.
    • (2003) Circulation , vol.107 , pp. 817-823
    • Borer, J.S.1    Fox, K.2    Jaillon, P.3    Lerebours, G.4
  • 8
    • 27944492366 scopus 로고    scopus 로고
    • Efficacy of ivabradine, a new selective I(f) inhibitor, compared with atenolol in patients with chronic stable angina
    • Tardif JC, Ford I, Tendera M, Bourassa MG, Fox K. Efficacy of ivabradine, a new selective I(f) inhibitor, compared with atenolol in patients with chronic stable angina. Eur Heart J 2005;26:2529-2536.
    • (2005) Eur Heart J , vol.26 , pp. 2529-2536
    • Tardif, J.C.1    Ford, I.2    Tendera, M.3    Bourassa, M.G.4    Fox, K.5
  • 9
    • 24744465984 scopus 로고    scopus 로고
    • Antianginal and antiischemic effects of the if current inhibitor compared to amlodipine as monotherapies in patients with chronic stable angina. (Abstract). Randomised, controlled, double-blind trial
    • Ruzyllo W, Ford IF, Tendera MT, Fox KF. Antianginal and antiischemic effects of the If current inhibitor compared to amlodipine as monotherapies in patients with chronic stable angina. (Abstract). Randomised, controlled, double-blind trial. Eur Heart J 2004;25(Suppl.):878.
    • (2004) Eur Heart J , vol.25 , Issue.SUPPL. , pp. 878
    • Ruzyllo, W.1    Ford, I.F.2    Tendera, M.T.3    Fox, K.F.4
  • 11
    • 0036020147 scopus 로고    scopus 로고
    • Current-dependent block of rabbit sino-atrial node I(f) channels by ivabradine
    • Bucchi A, Baruscotti M, DiFrancesco D. Current-dependent block of rabbit sino-atrial node I(f) channels by ivabradine. J Gen Physiol 2002;120:1-13.
    • (2002) J Gen Physiol , vol.120 , pp. 1-13
    • Bucchi, A.1    Baruscotti, M.2    DiFrancesco, D.3
  • 12
    • 4544344025 scopus 로고    scopus 로고
    • Heart rate lowering by specific and selective if current inhibition with ivabradine. A new therapeutic perspective in cardiovascular disease
    • DiFrancesco D, Camm AJ. Heart rate lowering by specific and selective If current inhibition with ivabradine. A new therapeutic perspective in cardiovascular disease. Drugs 2004;64:1757-1765.
    • (2004) Drugs , vol.64 , pp. 1757-1765
    • DiFrancesco, D.1    Camm, A.J.2
  • 13
    • 0012457490 scopus 로고    scopus 로고
    • Hyperpolarization-activated cation currents: From molecules to physiological function
    • Robinson RB, Siegelbaum SA. Hyperpolarization-activated cation currents: from molecules to physiological function. Annu Rev Physiol 2003;65:453-480.
    • (2003) Annu Rev Physiol , vol.65 , pp. 453-480
    • Robinson, R.B.1    Siegelbaum, S.A.2
  • 14
    • 0042357093 scopus 로고    scopus 로고
    • Electrophysiological effects of a single intravenous administration of ivabradine (S 16257) in adult patients with normal baseline electrophysiology
    • Camm AJ, Lau CP. Electrophysiological effects of a single intravenous administration of ivabradine (S 16257) in adult patients with normal baseline electrophysiology. Drugs R D 2003;4:83-89.
    • (2003) Drugs R D , vol.4 , pp. 83-89
    • Camm, A.J.1    Lau, C.P.2
  • 15
    • 0035021986 scopus 로고    scopus 로고
    • Evaluation of drug-induced QT interval prolongation: Implications for drug approval and labelling
    • Malik M, Camm AJ. Evaluation of drug-induced QT interval prolongation: implications for drug approval and labelling. Drug Saf 2001;24:323-351.
    • (2001) Drug Saf , vol.24 , pp. 323-351
    • Malik, M.1    Camm, A.J.2
  • 16
    • 33745472240 scopus 로고    scopus 로고
    • Absence of direct effects of the if current blocker ivabradine on ventricular repolarization: Analysis based on a population heart rate correction formula
    • Abstract
    • Savelieva I, Camm AJ. Absence of direct effects of the If current blocker ivabradine on ventricular repolarization: analysis based on a population heart rate correction formula. (Abstract). J Am Coll Cardiol 2005;45:95A.
    • (2005) J Am Coll Cardiol , vol.45
    • Savelieva, I.1    Camm, A.J.2
  • 17
    • 33747890788 scopus 로고    scopus 로고
    • Noninvasive electrophysiological study of ivabradine (NESI) in patients with dual chamber pacemakers: Effects on ventricular repolarization
    • Abstract
    • Savelieva I, Jones S, Dougal K, Malik M, Camm AJ. Noninvasive electrophysiological study of ivabradine (NESI) in patients with dual chamber pacemakers: effects on ventricular repolarization. (Abstract). J Am Coll Cardiol 2006;47:27A.
    • (2006) J Am Coll Cardiol , vol.47
    • Savelieva, I.1    Jones, S.2    Dougal, K.3    Malik, M.4    Camm, A.J.5
  • 18
    • 0142169934 scopus 로고    scopus 로고
    • Anti-ischemic effects of ivabradine, a selective heart rate-reducing agent, in exercise-induced myocardial ischemia in pigs
    • Vilaine JP, Bidouard JP, Lesage L, Reure H, Peglion JL. Anti-ischemic effects of ivabradine, a selective heart rate-reducing agent, in exercise-induced myocardial ischemia in pigs. J Cardiovasc Pharmacol 2003;42:688-696.
    • (2003) J Cardiovasc Pharmacol , vol.42 , pp. 688-696
    • Vilaine, J.P.1    Bidouard, J.P.2    Lesage, L.3    Reure, H.4    Peglion, J.L.5
  • 19
    • 0029582832 scopus 로고
    • Coronary and hemodynamic effects of S 16257, a new bradycardic agent, in resting and exercising conscious dogs
    • Simon L, Ghaleh B, Puybasset L, Giudicelli JF, Berdeaux A. Coronary and hemodynamic effects of S 16257, a new bradycardic agent, in resting and exercising conscious dogs. J Pharmacol Exp Ther 1995;275:659-666.
    • (1995) J Pharmacol Exp Ther , vol.275 , pp. 659-666
    • Simon, L.1    Ghaleh, B.2    Puybasset, L.3    Giudicelli, J.F.4    Berdeaux, A.5
  • 22
    • 0344394916 scopus 로고    scopus 로고
    • A single intravenous dose of ivabradine, a novel I(f) inhibitor, lowers heart rate but does not depress left ventricular function in patients with left ventricular dysfunction
    • Manz M, Reuter M, Lauck G, Omran H, Jung W. A single intravenous dose of ivabradine, a novel I(f) inhibitor, lowers heart rate but does not depress left ventricular function in patients with left ventricular dysfunction. Cardiology 2003;100:149-155.
    • (2003) Cardiology , vol.100 , pp. 149-155
    • Manz, M.1    Reuter, M.2    Lauck, G.3    Omran, H.4    Jung, W.5
  • 23
    • 11144356194 scopus 로고    scopus 로고
    • Long-term heart rate reduction induced by the selective I(f) current inhibitor ivabradine improves left ventricular function and intrinsic myocardial structure in congestive heart failure
    • Mulder P, Barbier S, Chagraoui A, Richard V, Henry JP, Lallemand F, Renet S, Lerebours G, Mahlberg-Gaudin F, Thuillez C. Long-term heart rate reduction induced by the selective I(f) current inhibitor ivabradine improves left ventricular function and intrinsic myocardial structure in congestive heart failure. Circulation 2004;109:1674-1679.
    • (2004) Circulation , vol.109 , pp. 1674-1679
    • Mulder, P.1    Barbier, S.2    Chagraoui, A.3    Richard, V.4    Henry, J.P.5    Lallemand, F.6    Renet, S.7    Lerebours, G.8    Mahlberg-Gaudin, F.9    Thuillez, C.10
  • 24
    • 13244275563 scopus 로고    scopus 로고
    • Effect of ivabradine in patients with left ventricular systolic dysfunction and coronary artery disease
    • Abstract
    • Jondeau G, Korewicki J, Vasiliauskas D. Effect of ivabradine in patients with left ventricular systolic dysfunction and coronary artery disease. (Abstract). Eur Heart J Suppl 2004;25:2637.
    • (2004) Eur Heart J Suppl , vol.25 , pp. 2637
    • Jondeau, G.1    Korewicki, J.2    Vasiliauskas, D.3
  • 25
    • 33748781606 scopus 로고    scopus 로고
    • Rationale and design of a randomized, double-blind, placebo-controlled trial of ivabradine in patients with stable coronary artery disease and left ventricular dysfunction: The morBidity-mortality EvAlUation of the if inhibitor ivabradine in patients with coronary disease and left ventricULar dysfunction (BEAUTIFUL) Study
    • in press
    • Fox K, Ferrari R, Tendera M, Steg PG, Ford I. Rationale and design of a randomized, double-blind, placebo-controlled trial of ivabradine in patients with stable coronary artery disease and left ventricular dysfunction: the morBidity-mortality EvAlUation of the If inhibitor ivabradine in patients with coronary disease and left ventricULar dysfunction (BEAUTIFUL) Study. Am Heart J 2006, in press.
    • (2006) Am Heart J
    • Fox, K.1    Ferrari, R.2    Tendera, M.3    Steg, P.G.4    Ford, I.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.