Characterization of homogentisate prenyltransferases involved in plastoquinone-9 and tocochromanol biosynthesis

FEBS Letters

Volumn 580, Issue 22, 2006, Pages 5357-5362

  Sadre, Radin ^a   Gruber, Jens ^a   Frentzen, Margrit ^a  

^a RWTH AACHEN UNIVERSITY   (Germany)

Author keywords

2 Methyl 6 solanesyl 1,4 benzoquinol; Homogentisate; Plastoquinone 9; Prenyltransferases; Substrate specificity; Tocopherol

Indexed keywords

CHROMAN DERIVATIVE; COMPLEMENTARY DNA; DIMETHYLALLYLTRANSFERASE; PLASTOQUINONE 9; PYROPHOSPHATE; QUINONE DERIVATIVE; TOCOCHROMANOL; UNCLASSIFIED DRUG;

ARABIDOPSIS; ARTICLE; BIOSYNTHESIS; CHLAMYDOMONAS REINHARDTII; ENZYME ACTIVITY; ESCHERICHIA COLI; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANIMALS; ARABIDOPSIS; ARABIDOPSIS PROTEINS; CHLAMYDOMONAS REINHARDTII; DIMETHYLALLYLTRANSTRANSFERASE; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; PLASTOQUINONE; PROTOZOAN PROTEINS; SYNECHOCYSTIS; TOCOPHEROLS;

ARABIDOPSIS THALIANA; CHLAMYDOMONAS REINHARDTII; ESCHERICHIA COLI; SYNECHOCYSTIS;

EID: 33748802545     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2006.09.002     Document Type: Article

References (22)

1. Hutson K.G., and Threlfall D.R. Synthesis of plastoquinone-9 and phytylplastoquinone from homogentisate in lettuce chloroplasts. Biochim. Biophys. Acta 632 (1980) 630-648
2. Soll J., and Schultz G. 2-Methyl-6-phytylquinol and 2,3-Dimethy-5-phytylquinol as precursors of tocopherol synthesis in spinach chloroplasts. Phytochemistry 19 (1980) 215-218
3. Soll J., Kemmerling M., and Schultz G. Tocopherol and plastoquinone synthesis in spinach chloroplasts subfractions. Arch. Biochem. Biophys. 204 (1980) 544-550
4. Soll J., Schultz G., Joyard J., Douce R., and Block M.A. Localization and synthesis of prenylquinones in isolated outer and inner envelope membranes from spinach chloroplasts. Arch. Biochem. Biophys. 238 (1985) 290-299
5. Collakova E., and DellaPenna D. Isolation and functional analysis of homogentisate phytyltransferase from Synechocystis sp. PCC 6803 and Arabidopsis. Plant Physiol. 127 (2001) 1113-1124
6. Savidge B., Weiss J.D., Wong Y.H., Lassner M.W., Mitsky T.A., Shewmaker C.K., Post-Beittenmiller D., and Valentin H.E. Isolation and characterization of homogentisate phytyltransferase genes from Synechocystis sp. PCC 6803 and Arabidopsis. Plant Physiol. 129 (2002) 321-332
7. Collakova E., and DellaPenna D. Homogentisate phytyltransferase activity is limiting for tocopherol biosynthesis in Arabidopsis. Plant Physiol. 131 (2003) 632-642
8. Cahoon E.B., Hall S.E., Ripp K.G., Ganzke T.S., Hitz W.D., and Coughlan S.J. Metabolic redesign of vitamin E biosynthesis in plants for tocotrienol production and increased antioxidant content. Nat. Biotechnol. 21 (2003) 1082-1087
9. Venkatesh T.V., Karunanandaa B., Free D.L., Rottnek J.M., Baszis S.R., and Valentin H.E. Identification and characterization of an Arabidopsis homogentisate phytyltransferase paralog. Planta 223 (2006) 1134-1144
10. Sattler S.E., Gilliland L.U., Magallanes-Lundback M., Pollard M., and DellaPenna D. Vitamin E is essential for seed longevity and for preventing lipid peroxidation during germination. Plant Cell 16 (2004) 1419-1432
11. Havaux M., Eymery F., Porfirova S., Rey P., and Dörmann P. Vitamin E protects against photoinhibition and photooxidative stress in Arabidopsis thaliana. Plant Cell 17 12 (2005) 3451-3469
12. Schledz M., Seidler A., Beyer P., and Neuhaus G. A novel phytyltransferase from Synechocystis sp. PCC 6803 involved in tocopherol biosynthesis. FEBS Lett. 499 (2001) 15-20
13. Müller F., and Frentzen M. Phosphatidylglycerophosphate synthases from Arabidopsis thaliana. FEBS Lett. 509 (2001) 298-302
14. Raclaru M., Gruber J., Kumar R., Sadre R., Lühs W., Zarhloul M.K., Friedt W., Frentzen M., and Weier D. Increase of the tocochromanol content in transgenic Brassica napus seeds by overexpression of key enzymes involved in prenylquinone biosynthesis. Mol. Breeding. 18 (2006) 93-107
15. Soll J. α-Tocopherol and plastoquinone synthesis in chloroplast membranes. Meth. Enzymol. 148 (1987) 383-392
16. Kumar R., Raclaru M., Schüßeler T., Gruber J., Sadre R., Lühs W., Zarhloul K.M., Friedt W., Enders D., Frentzen M., and Weier D. Characterisation of plant tocopherol cyclases and their overexpression in transgenic Brassica napus seeds. FEBS Lett. 579 (2005) 1357-1364
17. Pennock J.F. Biosynthesis of plastoquinone. Meth. Enzymol. 110 (1985) 313-319
18. Clough S., and Bent A. Floral dip: a simplified method for Agrobacterium-mediated transformation of Arabidopsis thaliana. Plant J. 16 (1998) 735-743
19. Emanuelsson O., Nielsen H., and von Heijne G. ChloroP, a neural network-based method for predicting chloroplast transit peptides and their cleavage sites. Protein Science 8 (1999) 978-984
20. Sadre R., Paus H., Frentzen M., and Weier D. Characterisation of enzymes involved in tocopherol biosynthesis. In: Murata N., et al. (Ed). Advanced Research on Plant Lipids (2003), Kluwer Academic Publishers, Dordrecht 253-256
21. Norris S.R., Barrette T.R., and DellaPenna D. Genetic dissection of carotenoid synthesis in Arabidopsis defines plastoquinone as an essential component of phytoene desaturation. Plant Cell 7 (1995) 2139-2149
22. Karunanandaa B., Qi Q., Hao M., Baszis S.R., Jensen P.K., Wong Y.H., Jiang J., Venkatramesh M., Gruys K.J., Moshiri F., Post-Beittenmiller D., Weiss J.D., and Valentin H.E. Metabolically engineered oilseed crops with enhanced seed tocopherol. Metab. Eng. 7 (2005) 384-400