Involvement of innate immunity in the pathogenesis of chronic hepatitis C in children

Scandinavian Journal of Immunology

Volumn 64, Issue 4, 2006, Pages 425-432

  Wisniewska Ligier, M ^a   Wozniakowska Gesicka, T ^a   Glowacka, E ^a   Lewkowicz, P ^a   Banasik, M ^a   Tchorzewski, H ^a  

^a POLISH MOTHER S MEMORIAL HOSPITAL RESEARCH INSTITUTE   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; GRANULOCYTE COLONY STIMULATING FACTOR; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 8; PHORBOL 13 ACETATE 12 MYRISTATE; REACTIVE OXYGEN METABOLITE; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4;

ADOLESCENT; ADULT; ARTICLE; BLOOD; CELL DAMAGE; CELL STIMULATION; CHEMOLUMINESCENCE; CLINICAL ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; CORRELATION ANALYSIS; FEMALE; HEPATITIS C; HUMAN; INNATE IMMUNITY; LIVER CELL; MALE; METABOLISM; NECROSIS; NEUTROPHIL; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SCHOOL CHILD;

ADOLESCENT; CELLS, CULTURED; CHILD; CYTOKINES; FEMALE; HEPATITIS C, CHRONIC; HUMANS; IMMUNITY, NATURAL; MALE; NEUTROPHILS; OXYGEN; SUPEROXIDES; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 4;

EID: 33748773303     PISSN: 03009475     EISSN: 13653083     Source Type: Journal    
DOI: 10.1111/j.1365-3083.2006.01800.x     Document Type: Article

References (42)

1. Chang KM. Immunopathogenesis of hepatitis C virus infection. Clin Liver Dis 2003;7:89-105.
2. Grakoui A. Hepatitis C virus infection. How does the host respond? Minerva Gastroenterol Dietol 2004;50:21-8.
3. Crovatto M, Pozzato G, Zorat F et al. Peripheral blood neutrophils from hepatitis C virus-infected patients are replication sites of the virus. Haematologica 2000;85:356-61.
4. Vabulas RM, Ahmed-Nejad P, Ghose S, Kirschning CJ, Issels RD, Wagner H. HSP70 as endogenous stimulus of the Toll/interleukin-1 receptor signal pathway. J Biol Chem 2002;277:15107-12.
5. Vabulas RM, Braedel S, Hilf N et al. The endoplasmic reticulum-resident heat shock protein Gp96 activates dendritic cells via the Toll-like receptor 2/4 pathway. J Biol Chem 2002;277:20847-53.
6. Johnson GB, Brunn GJ, Tang AH, Platt JL. Evolutionary clues to the functions of the Toll-like family as surveillance receptors. Trends Immunol 2003;24:19-24.
7. Choi J, Lee KJ, Zheng Y, Yamaga AK, Lai MM, Ou JH. Reactive oxygen species suppress hepatitis C virus RNA replication in human hepatoma cells. Hepatology 2004;39:81-9.
8. Kim JY, Ro JY. Signal pathway of cytokines produced by reactive oxygen species generated from phorbol myristate acetate-stimulated HMC-1 cells. Scand J Immunol 2005;62:25-35.
9. Asehnoune K, Strasshein D, Mitra S, Kim JY, Abraham E. Involvement of reactive oxygen species in Toll-like receptor 4-dependent activation of NF-kappa B. J Immunol 2004;172:2522-59.
10. Soulas P, Woods A, Jaulhac B et al. Autoantigen, innate immunity, and T cells cooperate to break B cell tolerance during bacterial infection. J Clin Invest 2005;115:2257-67.
11. Isaguliants MG, Ozeretskovskaya NN. Host background factors contributing to hepatitis C virus clearance. Curr Pharm Biotechnol 2003;4:185-93.
12. Ishak K, Baptista A, Bianchi L et al. Histological grading and staging of chronic hepatitis. J Hepatol 1995;22:696-9.
13. Knodell RG, Ishak KG, Black WC et al. Formulation and application of a numerical scoring system for assessing histological activity in asymptomatic chronic active hepatitis. Hepatology 1981;1:431-5.
14. Smith JA. Neutrophils, host defense, and inflammation: a double-edged sword. J Leukoc Biol 1994;55:672-91.
15. Hampton MB, Kettle AJ, Winterbourn CC. Inside the neutrophil phagosome: oxidants, myeloperoxidase, and bacterial killing. Blood 1998;92:3007-17.
16. Weiss SJ. Tissue destruction by neutrophils. N Engl J Med 1989;320:365-76.
17. Akira S, Takeda K. Toll-like receptor signaling. Nat Rev Immunol 2004;4:499-511.
18. Kaisho T, Hoshino K, Iwabe T, Takeuchi O, Yasui T, Akira S. Endotoxin can induce MyD88-deficient dendritic cells to support Th2 cell differentiation. Int Immunol 2002;14:695-700.
19. Hopkins PA, Sriskandan S. Mammalian Toll-like receptors: to immunity and behind. Clin Exp Immunol 2005;140:395-407.
20. Beg AA. Endogenous ligands of Toll-like receptors: implications for regulating inflammatory and immune responses. Trends Immunol 2002;23:509-12.
21. Renshaw M, Rockwell J, Engleman C, Gewirtz A, Katz J, Sambhara S. Cutting edge: impaired Toll-like receptor expression and function in aging. J Immunol 2002;169:4697-701.
22. Riordan SM, Skinner N, Nagree A et al. Peripheral blood mononuclear cell expression of toll-like receptors and relation to cytokine levels in cirrhosis. Hepatology 2003;37:1154-64.
23. Lauener RP, Birchler T, Adamski J et al. Expression of CD14 and Toll-like receptor 2 in farmers' and non-farmers' children. Lancet 2002;360:465-6.
24. Hayashi F, Means TK, Luster AD. Toll-like receptors stimulate human neutrophil function. Blood 2003;102:2660-9.
25. Kurt-Jones EA, Mandell L, Whitney C et al. Role of toll-like receptor 2 (TLR2) in neutrophil activation: GM-CSF enhances TLR2 expression and TLR2-mediated interleukin 8 responses in neutrophils. Blood 2002;100:1860-8.
26. Flo TH, Halaas O, Torp S et al. Differential expression of Toll-like receptor 2 in human cells. J Leukoc Biol 2001;69:474-81.
27. Paik YH, Schwabe RF, Bataller R, Russo MP, Jobin C, Brenner DA. Toll-like receptor 4 mediates inflammatory signaling by bacterial lipopolysaccharide in human hepatic stellate cells. Hepatology 2003;37:1047-55.
28. Hoebe K, Janssen E, Beutler B. The interface between innate and adaptive immunity. Nat Immunol 2004;5:971-4.
29. Uehara M, Sato N. Impaired ability of neutrophils to produce oxygen-derived free radicals in patients with chronic liver disease and hepatocellular carcinoma. Hepatology 1994;20:326-30.
30. Borowski P, Wiesch JS, Resch K, Feucht H, Laufs R, Schmitz H. Protein kinase C recognizes the protein kinase A-binding motif of nonstructural protein 3 of hepatitis C virus. J Biol Chem 1999;274:30722-8.
31. Bureau C, Bernad J, Chaouchel N et al. Nonstructural 3 protein of hepatitis C virus triggers an oxidative burst in human monocytes via activation of NADPH oxidase. J Biol Chem 2001;276:23077-83.
32. Giannelli G, Piazzolla G, Tortorella C, Jirillo E, Schiraldi O, Antonaci S. Neutrophil oxidative responsiveness in chronic hepatitis C. Med Sci Res 1996;24:99-101.
33. Piazzolla G, Giannelli G, Antonelli G et al. Effects of interferon-alpha treatment on neutrophil oxidative metabolism, lymphocyte proliferation and monocyte HLA class I antigen expression in patients with chronic hepatitis C. Immunopharmacol Immunotoxicol 1996;18:529-48.
34. Toro F, Conesa A, Garcia A, Bianco NE, De Sanctis JB. Increased peroxide production by polymorphonuclear cells of chronic hepatitis C virus-infected patients. Clin Immunol Immunopathol 1998;88:169-75.
35. Cerutti AP. Oxy-radicals and cancer. Lancet 1994;344:862-3.
36. Wiseman H, Halliwell B. Damage to DNA by reactive oxygen and nitrogen species: role in inflammatory disease and progression to cancer. Biochem J 1996;313:17-29.
37. Nakamura H, Nakamura K, Yodoi J. Redox regulation of cellular activation. Annu Rev Immunol 1997;15:351-69.
38. Suzuki YJ, Forman HJ, Sevanian A. Oxidants as stimulators of signal transduction. Free Radic Biol Med 1997;22:269-85.
39. Hirschfeld M, Ma Y, Weis JH, Vogel SN, Weis JJ. Repurification of lipopolysaccharide eliminates signaling through both human and murine toll-like receptor 2. J Immunol 2000;165:618-22.
40. Sabroe I, Prince LR, Jones EC et al. Selective roles for Toll-like receptor TLR2 and TLR4 in the regulation of neutrophil activation and life span. J Immunol 2003;170:5268-75.
41. Sarih M, Bouchrit N, Benslimane A. Different cytokine profiles of peripheral blood mononuclear cells from patients with persistent and self-limited hepatitis C virus infection. Immunol Lett 2000;74:117-20.
42. Eisen-Vandervelde AL, Waggoner SN, Yao ZQ, Cale EM, Hahn CS, Hahn YS. Hepatitis C virus core selectively suppresses interleukin-12 synthesis in human macrophages by interfering with AP-1 activation. J Biol Chem 2004;279:43479-86.