Use of mesothelin as a marker for mesothelial cells in cytologic specimens

Seminars in Diagnostic Pathology

Volumn 23, Issue 1, 2006, Pages 20-24

  Kachali, Cornelius ^a   Eltoum, Isam ^a   Horton, Debra ^a   Chhieng, David C ^a  

^a University of Alabama at Birmingham   (United States)

Author keywords

Adenocarcinoma; Body Cavity Fluid; Cytology; Immunohistochemistry; Mesothelin; Mesothelioma

Indexed keywords

CALRETININ; MESOTHELIN;

ADULT; ANTIBODY DETECTION; ARTICLE; CANCER PATIENT; CLINICAL ARTICLE; CYTOPATHOLOGY; DIAGNOSTIC ACCURACY; DISEASE MARKER; FEMALE; FOLLOW UP; HUMAN; HUMAN TISSUE; IMMUNOCYTOCHEMISTRY; IMMUNOREACTIVITY; INFORMATION RETRIEVAL; INTERMETHOD COMPARISON; LUNG ADENOCARCINOMA; MALE; MALIGNANT MESOTHELIOMA; MEDICAL RECORD; MESOTHELIUM CELL; PLEURA EFFUSION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SAMPLE SIZE; STAINING; STATISTICAL SIGNIFICANCE; TISSUE SECTION;

ADENOCARCINOMA; ASCITIC FLUID; CALCIUM-BINDING PROTEIN, VITAMIN D-DEPENDENT; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MEMBRANE GLYCOPROTEINS; MESOTHELIOMA; MIDDLE AGED; PLEURAL EFFUSION; SENSITIVITY AND SPECIFICITY; TUMOR MARKERS, BIOLOGICAL;

EID: 33748762293     PISSN: 07402570     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.semdp.2006.06.006     Document Type: Article

References (35)

1. Domagala W., and Woyke S. Transmission and scanning electron microscopic studies of cells in effusions. Acta Cytol 19 (1975) 214-224
2. Bauer Z., Milic N., Handl S., et al. The results of some cytochemical reactions in metastatic malignant tumor cells in pleural and peritoneal effusions. Acta Cytol 21 (1977) 141-146
3. Koss L.G., and Domagala W. Configuration of surfaces of human cancer cells in effusions. A review. Scanning Electron Microscopy 3 (1980) 89-100
4. Unger K.M., Raber M., Bedrossian C.W., et al. Analysis of pleural effusions using automated flow cytometry. Cancer 52 (1983) 873-877
5. Ghosh A.K., Spriggs A.I., Taylor-Papadimitriou J., et al. Immunocytochemical staining of cells in pleural and peritoneal effusions with a panel of monoclonal antibodies. J Clin Pathol 36 (1983) 1154-1164
6. Halter S.A., Hunt L.S., Roche B., et al. Backscatter electron imaging of cells from effusions. Scanning Electron Microscopy 4 (1984) 1883-1892
7. Walts A.E., Said J.W., Shintaku I.P., et al. Keratins of different molecular weight in exfoliated mesothelial and adenocarcinoma cells: an aid to cell identification. Am J Clin Pathol 81 (1984) 442-446
8. Bousfield L.R., Greenberg M.L., and Pacey F. Cytogenetic diagnosis of cancer from body fluids. Acta Cytol 29 (1985) 768-774
9. Mason M.R., Bedrossian C.W., and Fahey C.A. Value of immunocytochemistry in the study of malignant effusions. Diagn Cytopathol 3 (1987) 215-221
10. Cibas E.S., Corson J.M., and Pinkus G.S. The distinction of adenocarcinoma from malignant mesothelioma in cell blocks of effusions: the role of routine mucin histochemistry and immunohistochemical assessment of carcinoembryonic antigen, keratin proteins, epithelial membrane antigen, and milk fat globule-derived antigen. Hum Pathol 18 (1987) 67-74
11. Silverman J.F., Nance K., Phillips B., et al. The use of immunoperoxidase panels for the cytologic diagnosis of malignancy in serous effusions. Diagn Cytopathol 3 (1987) 134-140
12. Esteban J.M., Yokota S., Husain S., et al. Immunocytochemical profile of benign and carcinomatous effusions. A practical approach to difficult diagnosis. Am J Clin Pathol 94 (1990) 698-705
13. Delahaye M., Hoogsteden H.C., and Van der Kwast T.H. Immunocytochemistry of malignant mesothelioma: OV632 as a marker of malignant mesothelioma. J Pathol 165 (1991) 137-143
14. Nance K.V., and Silverman J.F. Immunocytochemical panel for the identification of malignant cells in serous effusions. Am J Clin Pathol 95 (1991) 867-874
15. Chang K., Pai L.H., Pass H., et al. Monoclonal antibody K1 reacts with epithelial mesothelioma but not with lung adenocarcinoma. Am J Surg Pathol 16 (1992) 259-268
16. Donna A., Betta P.G., Bellingeri D., et al. Cytologic diagnosis of malignant mesothelioma in serous effusions using an antimesothelial-cell antibody. Diagn Cytopathol 8 (1992) 361-365
17. Clark S.P., Chou S.T., Martin T.J., et al. Parathyroid hormone-related protein antigen localization distinguishes between mesothelioma and adenocarcinoma of the lung. J Pathol 176 (1995) 161-165
18. Fetsch P.A., Abati A., and Hijazi Y.M. Utility of the antibodies CA 19-9, HBME-1, and thrombomodulin in the diagnosis of malignant mesothelioma and adenocarcinoma in cytology. Cancer 84 (1998) 101-108
19. Skov B.G., Stahel R.A., and Hirsch F. ME1-antibody labelling of primary bronchogenic tumours and extrapulmonary malignancies. Lung Cancer 11 (1994) 221-227
20. Rogers J.H. Calretinin: a gene for a novel calcium-binding protein expressed principally in neurons. J Cell Biol 105 (1987) 1343-1353
21. Doglioni C., Tos A.P., Laurino L., et al. Calretinin: a novel immunocytochemical marker for mesothelioma. Am J Surg Pathol 20 (1996) 1037-1046
22. Gotzos V., Vogt P., and Celio M.R. The calcium binding protein calretinin is a selective marker for malignant pleural mesotheliomas of the epithelial type. Pathol Res Pract 192 (1996) 137-147
23. Riera J.R., Astengo-Osuna C., Longmate J.A., et al. The immunohistochemical diagnostic panel for epithelial mesothelioma: a reevaluation after heat-induced epitope retrieval. Am J Surg Pathol 21 (1997) 1409-1419
24. Leers M.P., Aarts M.M., and Theunissen P.H. E-cadherin and calretinin: a useful combination of immunochemical markers for differentiation between mesothelioma and metastatic adenocarcinoma. Histopathology 32 (1998) 209-216
25. Chhieng D.C., Yee H., Schaefer D., et al. Calretinin staining pattern aids in the differentiation of mesothelioma from adenocarcinoma in serous effusions. Cancer 90 (2000) 194-200
26. Chang K., and Pastan I. Molecular cloning of mesothelin, a differentiation antigen present on mesothelium, mesotheliomas, and ovarian cancers. Proc Natl Acad Sci U S A 93 (1996) 136-140
27. Ordonez N.G. Value of mesothelin immunostaining in the diagnosis of mesothelioma. Mod Pathol 16 (2003) 192-197
28. Ordonez N.G. The immunohistochemical diagnosis of mesothelioma: a comparative study of epithelioid mesothelioma and lung adenocarcinoma. Am J Surg Pathol 27 (2003) 1031-1051
29. Miettinen M., and Sarlomo-Rikala M. Expression of calretinin, thrombomodulin, keratin 5, and mesothelin in lung carcinomas of different types: an immunohistochemical analysis of 596 tumors in comparison with epithelioid mesotheliomas of the pleura. Am J Surg Pathol 27 (2003) 150-158
30. Youden W.J. Index for rating diagnostic tests. Cancer. 1 (1950) 32-35
31. Kojima T., Oh-eda M., Hattori K., et al. Molecular cloning and expression of megakaryocyte potentiating factor cDNA. J Biol Chem 270 (1995) 21984-21990
32. Frierson Jr. H.F., Moskaluk C.A., Powell S.M., et al. Large-scale molecular and tissue microarray analysis of mesothelin expression in common human carcinomas. Hum Pathol 34 (2003) 605-609
33. Ordonez N.G. Application of mesothelin immunostaining in tumor diagnosis. Am J Surg Pathol 27 (2003) 1418-1428
34. Argani P., Iacobuzio-Donahue C., Ryu B., et al. Mesothelin is overexpressed in the vast majority of ductal adenocarcinomas of the pancreas: identification of a new pancreatic cancer marker by serial analysis of gene expression (SAGE). Clin Cancer Res 7 (2001) 3862-3868
35. Bera T.K., and Pastan I. Mesothelin is not required for normal mouse development or reproduction. Mol Cell Biol 20 (2000) 2902-2906