Human monoclonal antibodies to domain C of tenascin-C selectively target solid tumors in vivo

Protein Engineering, Design and Selection

Volumn 19, Issue 10, 2006, Pages 471-478

  Silacci, Michela ^a   Brack, Simon S ^a   Späth, Nicolas ^b   Buck, Alfred ^b   Hillinger, Sven ^b   Arni, Stephan ^b   Weder, Walter ^b   Zardi, Luciano ^c   Neri, Dario ^a  

^a ETH ZURICH   (Switzerland)

^b UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^c G GASLINI INSTITUTE   (Italy)

Author keywords

Angiogenesis; Antibody phage display; Human monoclonal antibodies; Tenascin c; Tumor targeting

Indexed keywords

ANGIOGENESIS; ANTIBODY PHAGE DISPLAY; HUMAN MONOCLONAL ANTIBODIES; TENASCIN-C; TUMOR TARGETING;

BLOOD; BRAIN; DISSOCIATION; DRUG PRODUCTS; GLUCOSE; TUMORS;

ANTIBODIES;

FLUORODEOXYGLUCOSE F 18; HYBRID PROTEIN; INTERLEUKIN 2; ISOPROTEIN; MONOCLONAL ANTIBODY; TENASCIN; TRACER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTOMA; BACTERIOPHAGE; CANCER GRADING; CANCER GRAFT; CANCER MODEL; CONTROLLED STUDY; DISSOCIATION CONSTANT; DRUG TARGETING; GLIOMA; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; LUNG CANCER; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; RADIOIODINATION; SOLID TUMOR; TECHNOLOGY; TUMOR LOCALIZATION;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, MONOCLONAL; CELL LINE, TUMOR; GLIOMA; HUMANS; IMMUNOTHERAPY; KINETICS; MOLECULAR SEQUENCE DATA; NEOPLASMS; PEPTIDE LIBRARY; PROTEIN STRUCTURE, TERTIARY; RATS; RECOMBINANT FUSION PROTEINS; TENASCIN;

EID: 33748762207     PISSN: 17410126     EISSN: 17410134     Source Type: Journal    
DOI: 10.1093/protein/gzl033     Document Type: Article

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