Identification and evaluation of antioxidant, analgesic/anti-inflammatory activity of the most active ninhydrin-phenol adducts synthesized

Bioorganic and Medicinal Chemistry

Volumn 14, Issue 21, 2006, Pages 7113-7120

  Prabhakar, K R ^a   Veerapur, V P ^a   Bansal, Punit ^a   Vipan, K Parihar ^a   Reddy, K M ^a   Barik, Atanu ^b   Reddy, Bharat Kumar D ^c   Reddanna, P ^c   Priyadarsini, K I ^b   Unnikrishnan, M K ^a  

^a MANIPAL COLLEGE OF PHARMACEUTICAL SCIENCES   (India)

^b BHABHA ATOMIC RESEARCH CENTRE   (India)

^c UNIVERSITY OF HYDERABAD   (India)

Author keywords

Analgesic; Anti inflammatory; Antioxidant; Free radicals; Ninhydrin phenol adducts

Indexed keywords

4B,11B DIHYDRO 4B,11B DIHYDRO 12H INDENO[1,2 B]NAPHTHO[2,3 D]FURAN 12 ONE; 4B,6,7,9B TETRAHYDROXY 4B,9B DIHYDRO 10H BENZO[B]INDENO[2,1 D]FURAN 10 ONE; 4B,6,9B TRIHYDROXY 4B,9B DIHYDRO 10H BENZO[B]INDENO[2,1 D]FURAN 10 ONE; 4B,7,9B TRIHYDROXY 4B,9B DIHYDRO 10H BENZO[B]INDENO[2,1 D]FURAN 10 ONE; 4B,7,9B TRIHYDROXY 8 METHYL 4B,9B, DIHYDRO 10H BENZO[B]INDENO[2,1]FURAN 10 ONE; FREE RADICAL; LIPOXYGENASE; NINHYDRIN; PHENOL; PROSTAGLANDIN SYNTHASE; UNCLASSIFIED DRUG;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG SYNTHESIS; ENZYME INHIBITION; MOUSE; NONHUMAN; STEADY STATE;

ANALGESICS; ANIMALS; ANTI-INFLAMMATORY AGENTS; ANTIOXIDANTS; CALORIMETRY, DIFFERENTIAL SCANNING; CYCLOOXYGENASE INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; FEMALE; FREE RADICALS; LIPOXYGENASE INHIBITORS; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MICE; NINHYDRIN; PHENOL; RATS; RATS, WISTAR; SPECTROPHOTOMETRY, INFRARED;

EID: 33748747670     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2006.06.068     Document Type: Article

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