-
1
-
-
0033609476
-
A randomized double-blind, multicenter plasma concentration controlled study of the safety and efficacy of oral mycophenolate mofetil for the prevention of acute rejection after kidney transplantation
-
van Gelder T, Hilbrands LB, Vanrenterghem Y, Weimar W, de Fijter JW, Squifflet JP, Hene RJ, Verpooten GA, Navarro MT, Hale MD, Nicholls AJ. A randomized double-blind, multicenter plasma concentration controlled study of the safety and efficacy of oral mycophenolate mofetil for the prevention of acute rejection after kidney transplantation. Transplantation 1999; 68: 261-6.
-
(1999)
Transplantation
, vol.68
, pp. 261-266
-
-
Van Gelder, T.1
Hilbrands, L.B.2
Vanrenterghem, Y.3
Weimar, W.4
De Fijter, J.W.5
Squifflet, J.P.6
Hene, R.J.7
Verpooten, G.A.8
Navarro, M.T.9
Hale, M.D.10
Nicholls, A.J.11
-
2
-
-
0035119174
-
A retrospective analysis of mycophenolic acid and ciclosporin concentrations with acute rejection in renal transplant recipients
-
Pillans PI, Rigby RJ, Kubler P, Willis C, Salm P, Tett SE, Taylor PJ. A retrospective analysis of mycophenolic acid and ciclosporin concentrations with acute rejection in renal transplant recipients. Clin Biochem 2001; 34: 77-81.
-
(2001)
Clin Biochem
, vol.34
, pp. 77-81
-
-
Pillans, P.I.1
Rigby, R.J.2
Kubler, P.3
Willis, C.4
Salm, P.5
Tett, S.E.6
Taylor, P.J.7
-
3
-
-
3042743984
-
Early adequate mycophenolic acid exposure is associated with less rejection in kidney transplantation
-
Kiberd BA, Lawen J, Fraser AD, Keough-Ryan T, Belitsky P. Early adequate mycophenolic acid exposure is associated with less rejection in kidney transplantation. Am J Transplant 2004; 4: 1079-83.
-
(2004)
Am J Transplant
, vol.4
, pp. 1079-1083
-
-
Kiberd, B.A.1
Lawen, J.2
Fraser, A.D.3
Keough-Ryan, T.4
Belitsky, P.5
-
4
-
-
0034897144
-
Current issues in therapeutic drug monitoring of mycophenolic acid: Report of a roundtable discussion
-
Shaw LM, Holt DW, Oellerich M, Meiser B, van Gelder T. Current issues in therapeutic drug monitoring of mycophenolic acid: report of a roundtable discussion. Ther Drug Monit 2001; 23: 305-15.
-
(2001)
Ther Drug Monit
, vol.23
, pp. 305-315
-
-
Shaw, L.M.1
Holt, D.W.2
Oellerich, M.3
Meiser, B.4
Van Gelder, T.5
-
5
-
-
0033014930
-
Identification of glucoside and carboxyl-linked glucuronide conjugates of mycophenolic acid in plasma of transplant recipients treated with mycophenolate mofetil
-
Shipkova M, Armstrong VW, Wieland E, Niedmann PD, Schutz E, Brenner-Weiss G, Voihsel M, Braun F, Oellerich M. Identification of glucoside and carboxyl-linked glucuronide conjugates of mycophenolic acid in plasma of transplant recipients treated with mycophenolate mofetil. Br J Pharmacol 1999; 126: 1075-82.
-
(1999)
Br J Pharmacol
, vol.126
, pp. 1075-1082
-
-
Shipkova, M.1
Armstrong, V.W.2
Wieland, E.3
Niedmann, P.D.4
Schutz, E.5
Brenner-Weiss, G.6
Voihsel, M.7
Braun, F.8
Oellerich, M.9
-
7
-
-
0035077881
-
The acyl glucuronide metabolite of mycophenolic acid inhibits the proliferation of human mononuclear leukocytes
-
Shipkova M, Wieland E, Schutz E, Wiese C, Niedmann PD, Oellerich M, Armstrong VW. The acyl glucuronide metabolite of mycophenolic acid inhibits the proliferation of human mononuclear leukocytes. Transplant Proc 2001; 33: 1080-1.
-
(2001)
Transplant Proc
, vol.33
, pp. 1080-1081
-
-
Shipkova, M.1
Wieland, E.2
Schutz, E.3
Wiese, C.4
Niedmann, P.D.5
Oellerich, M.6
Armstrong, V.W.7
-
8
-
-
0033995440
-
Induction of cytokine release by the acyl glucuronide of mycophenolic acid: A link to side effects?
-
Wieland E, Shipkova M, Schellhaas U, Schutz E, Niedmann PD, Armstrong VW, Oellerich M. Induction of cytokine release by the acyl glucuronide of mycophenolic acid: a link to side effects? Clin Biochem 2000; 33: 107-13.
-
(2000)
Clin Biochem
, vol.33
, pp. 107-113
-
-
Wieland, E.1
Shipkova, M.2
Schellhaas, U.3
Schutz, E.4
Niedmann, P.D.5
Armstrong, V.W.6
Oellerich, M.7
-
9
-
-
0141888480
-
Twelve-month evaluation of the clinical pharmacokinetics of total and free mycophenolic acid and its glucuronide metabolites in renal allograft recipients on low dose tacrolimus in combination with mycophenolate mofetil
-
Kuypers DR, Vanrenterghem Y, Squifflet JP, Mourad M, Abramowicz D, Oellerich M, Armstrong V, Shipkova M, Daems J. Twelve-month evaluation of the clinical pharmacokinetics of total and free mycophenolic acid and its glucuronide metabolites in renal allograft recipients on low dose tacrolimus in combination with mycophenolate mofetil. Ther Drug Monit 2003; 25: 609-22.
-
(2003)
Ther Drug Monit
, vol.25
, pp. 609-622
-
-
Kuypers, D.R.1
Vanrenterghem, Y.2
Squifflet, J.P.3
Mourad, M.4
Abramowicz, D.5
Oellerich, M.6
Armstrong, V.7
Shipkova, M.8
Daems, J.9
-
10
-
-
0030670814
-
Unexpected augmentation of mycophenolic acid pharmacokinetics in renal transplant patients receiving tacrolimus and mycophenolate mofetil in combination therapy, and analogous in vitro findings
-
Zucker K, Rosen A, Tsaroucha A, de Faria L, Roth D, Ciancio G, Esquenazi V, Burke G, Tzakis A, Miller J. Unexpected augmentation of mycophenolic acid pharmacokinetics in renal transplant patients receiving tacrolimus and mycophenolate mofetil in combination therapy, and analogous in vitro findings. Transpl Immunol 1997; 5: 225-32.
-
(1997)
Transpl Immunol
, vol.5
, pp. 225-232
-
-
Zucker, K.1
Rosen, A.2
Tsaroucha, A.3
De Faria, L.4
Roth, D.5
Ciancio, G.6
Esquenazi, V.7
Burke, G.8
Tzakis, A.9
Miller, J.10
-
11
-
-
0345713185
-
Drug interaction between mycophenolate mofetil and tacrolimus detectable within therapeutic mycophenolic acid monitoring in renal transplant patients
-
Hubner GI, Eismann R, Sziegoleit W. Drug interaction between mycophenolate mofetil and tacrolimus detectable within therapeutic mycophenolic acid monitoring in renal transplant patients. Ther Drug Monit 1999; 21: 536-9.
-
(1999)
Ther Drug Monit
, vol.21
, pp. 536-539
-
-
Hubner, G.I.1
Eismann, R.2
Sziegoleit, W.3
-
12
-
-
0033045618
-
Mycophenolic acid plasma concentrations in kidney allograft recipients with or without ciclosporin: A cross-sectional study
-
Smak Gregoor P, van Gelder T, Hesse CJ, van der Mast BJ, van Besouw NM, Weimar W. Mycophenolic acid plasma concentrations in kidney allograft recipients with or without ciclosporin: a cross-sectional study. Nephrol Dial Transplant 1999; 14: 706-8.
-
(1999)
Nephrol Dial Transplant
, vol.14
, pp. 706-708
-
-
Smak Gregoor, P.1
Van Gelder, T.2
Hesse, C.J.3
Van Der Mast, B.J.4
Van Besouw, N.M.5
Weimar, W.6
-
13
-
-
2442716361
-
Ciclosporin A but not tacrolimus, inhibits the biliary excretion of mycophenolic acid glucuronide possibly mediated by multidrug resistance-associated protein 2 in rats
-
Kobayashi M, Saitoh H, Tadano K, Takahashi Y, Hirano T. Ciclosporin A but not tacrolimus, inhibits the biliary excretion of mycophenolic acid glucuronide possibly mediated by multidrug resistance-associated protein 2 in rats. J Pharmacol Exp Ther 2004; 309: 1029-35.
-
(2004)
J Pharmacol Exp Ther
, vol.309
, pp. 1029-1035
-
-
Kobayashi, M.1
Saitoh, H.2
Tadano, K.3
Takahashi, Y.4
Hirano, T.5
-
14
-
-
0033023263
-
Evidence that tacrolimus augments the bioavailability of mycophenolate mofetil through the inhibition of mycophenolic acid glucuronidation
-
Zucker K, Tsaroucha A, Olson L, Esquenazi V, Tzakis A, Miller J. Evidence that tacrolimus augments the bioavailability of mycophenolate mofetil through the inhibition of mycophenolic acid glucuronidation. Ther Drug Monit 1999; 21: 35-43.
-
(1999)
Ther Drug Monit
, vol.21
, pp. 35-43
-
-
Zucker, K.1
Tsaroucha, A.2
Olson, L.3
Esquenazi, V.4
Tzakis, A.5
Miller, J.6
-
15
-
-
0034467567
-
Mycophenolic acid glucuronidation and its inhibition by non-steroidal antiinflammatory drugs in human liver and kidney
-
Vietri M, Pietrabissa A, Mosca F, Pacifici GM. Mycophenolic acid glucuronidation and its inhibition by non-steroidal antiinflammatory drugs in human liver and kidney. Eur J Clin Pharmacol 2000; 56: 659-64.
-
(2000)
Eur J Clin Pharmacol
, vol.56
, pp. 659-664
-
-
Vietri, M.1
Pietrabissa, A.2
Mosca, F.3
Pacifici, G.M.4
-
16
-
-
0037559414
-
Can xipamide or tacrolimus inhibit the glucuronidation of mycophenolic acid in rat liver slices?
-
Balogh A, Merkel U, Muller D. Can xipamide or tacrolimus inhibit the glucuronidation of mycophenolic acid in rat liver slices? Exp Toxicol Pathol 2003; 54: 375-9.
-
(2003)
Exp Toxicol Pathol
, vol.54
, pp. 375-379
-
-
Balogh, A.1
Merkel, U.2
Muller, D.3
-
17
-
-
0345161813
-
Sirolimus (rapamycin)-based therapy in human renal transplantation: Similar efficacy and different toxicity compared with ciclosporine
-
Sirolimus European Renal Transplant Study Group
-
Groth CG, Backman L, Morales JM, Calne R, Kreis H, Lang P, Touraine JL, Claesson K, Campistol JM, Durand D, Wramner L, Brattstrom C, Charpentier B. Sirolimus (rapamycin)-based therapy in human renal transplantation: similar efficacy and different toxicity compared with ciclosporine. Sirolimus European Renal Transplant Study Group. Transplantation 1999; 67: 1036-42.
-
(1999)
Transplantation
, vol.67
, pp. 1036-1042
-
-
Groth, C.G.1
Backman, L.2
Morales, J.M.3
Calne, R.4
Kreis, H.5
Lang, P.6
Touraine, J.L.7
Claesson, K.8
Campistol, J.M.9
Durand, D.10
Wramner, L.11
Brattstrom, C.12
Charpentier, B.13
-
18
-
-
0037184316
-
Kidney transplantation without calcineurin inhibitor drugs: A prospective, randomized trial of sirolimus versus ciclosporine
-
Flechner SM, Goldfarb D, Modlin C, Feng J, Krishnamurthi V, Mastroianni B, Savas K, Cook DJ, Novick AC. Kidney transplantation without calcineurin inhibitor drugs: a prospective, randomized trial of sirolimus versus ciclosporine. Transplantation 2002; 74: 1070-6.
-
(2002)
Transplantation
, vol.74
, pp. 1070-1076
-
-
Flechner, S.M.1
Goldfarb, D.2
Modlin, C.3
Feng, J.4
Krishnamurthi, V.5
Mastroianni, B.6
Savas, K.7
Cook, D.J.8
Novick, A.C.9
-
19
-
-
0034804744
-
From beach to bedside: History of the development of sirolimus
-
Napoli KL, Taylor PJ. From beach to bedside: history of the development of sirolimus. Ther Drug Monit 2001; 23: 559-86.
-
(2001)
Ther Drug Monit
, vol.23
, pp. 559-586
-
-
Napoli, K.L.1
Taylor, P.J.2
-
20
-
-
0034102949
-
Determination of the acyl glucuronide metabolite of mycophenolic acid in human plasma by HPLC and Emit
-
Shipkova M, Schutz E, Armstrong VW, Niedmann PD, Oellerich M, Wieland E. Determination of the acyl glucuronide metabolite of mycophenolic acid in human plasma by HPLC and Emit. Clin Chem 2000; 46: 365-72.
-
(2000)
Clin Chem
, vol.46
, pp. 365-372
-
-
Shipkova, M.1
Schutz, E.2
Armstrong, V.W.3
Niedmann, P.D.4
Oellerich, M.5
Wieland, E.6
-
21
-
-
10744232330
-
The conduct of in vitro and in vivo drug-drug interaction studies: A Pharmaceutical Research and Manufacturers of America (PhRMA) perspective
-
Bjornsson TD, Callaghan JT, Einolf HJ, Fischer V, Gan L, Grimm S, Kao J, King SP, Miwa G, Ni L, Kumar G, McLeod J, Obach RS, Roberts S, Roe A, Shah A, Snikeris F, Sullivan JT, Tweedie D, Vega JM, Walsh J, Wrighton SA. The conduct of in vitro and in vivo drug-drug interaction studies: a Pharmaceutical Research and Manufacturers of America (PhRMA) perspective. Drug Metab Dispos 2003; 31: 815-32.
-
(2003)
Drug Metab Dispos
, vol.31
, pp. 815-832
-
-
Bjornsson, T.D.1
Callaghan, J.T.2
Einolf, H.J.3
Fischer, V.4
Gan, L.5
Grimm, S.6
Kao, J.7
King, S.P.8
Miwa, G.9
Ni, L.10
Kumar, G.11
McLeod, J.12
Obach, R.S.13
Roberts, S.14
Roe, A.15
Shah, A.16
Snikeris, F.17
Sullivan, J.T.18
Tweedie, D.19
Vega, J.M.20
Walsh, J.21
Wrighton, S.A.22
more..
-
22
-
-
11144318750
-
Identification of the udp-glucuronosyltransferase isoforms involved in mycophenolic Acid phase II metabolism
-
Picard N, Ratanasavanh D, Premaud A, Le Meur Y, Marquet P. Identification of the udp-glucuronosyltransferase isoforms involved in mycophenolic Acid phase II metabolism. Drug Metab Dispos 2005; 33: 139-46.
-
(2005)
Drug Metab Dispos
, vol.33
, pp. 139-146
-
-
Picard, N.1
Ratanasavanh, D.2
Premaud, A.3
Le Meur, Y.4
Marquet, P.5
-
23
-
-
0036249921
-
Inhibition of mycophenolic acid glucuronidation by niflumic acid in human liver microsomes
-
Vietri M, Pietrabissa A, Mosca F, Pacifici GM. Inhibition of mycophenolic acid glucuronidation by niflumic acid in human liver microsomes. Eur J Clin Pharmacol 2002; 58: 93-7.
-
(2002)
Eur J Clin Pharmacol
, vol.58
, pp. 93-97
-
-
Vietri, M.1
Pietrabissa, A.2
Mosca, F.3
Pacifici, G.M.4
-
24
-
-
9644258582
-
Comparison of liquid chromatography-tandem mass spectrometry with a commercial enzyme-multiplied immunoassay for the determination of plasma MPA in renal transplant recipients and consequences for therapeutic drug monitoring
-
Premaud A, Rousseau A, Le Meur Y, Lachatre G, Marquet P. Comparison of liquid chromatography-tandem mass spectrometry with a commercial enzyme-multiplied immunoassay for the determination of plasma MPA in renal transplant recipients and consequences for therapeutic drug monitoring. Ther Drug Monit 2004; 26: 609-19.
-
(2004)
Ther Drug Monit
, vol.26
, pp. 609-619
-
-
Premaud, A.1
Rousseau, A.2
Le Meur, Y.3
Lachatre, G.4
Marquet, P.5
-
25
-
-
0035512677
-
The glucuronidation of mycophenolic acid by human liver, kidney and jejunum microsomes
-
Bowalgaha K, Miners JO. The glucuronidation of mycophenolic acid by human liver, kidney and jejunum microsomes. Br J Clin Pharmacol 2001; 52: 605-9.
-
(2001)
Br J Clin Pharmacol
, vol.52
, pp. 605-609
-
-
Bowalgaha, K.1
Miners, J.O.2
-
26
-
-
0035079669
-
Glucuronide and glucoside conjugation of mycophenolic acid by human liver, kidney and intestinal microsomes
-
Shipkova M, Strassburg CP, Braun F, Streit F, Grone HJ, Armstrong VW, Tukey RH, Oellerich M, Wieland E. Glucuronide and glucoside conjugation of mycophenolic acid by human liver, kidney and intestinal microsomes. Br J Pharmacol 2001; 132: 1027-34.
-
(2001)
Br J Pharmacol
, vol.132
, pp. 1027-1034
-
-
Shipkova, M.1
Strassburg, C.P.2
Braun, F.3
Streit, F.4
Grone, H.J.5
Armstrong, V.W.6
Tukey, R.H.7
Oellerich, M.8
Wieland, E.9
-
28
-
-
7944223784
-
A phase I trial of pharmacologic modulation of irinotecan with ciclosporine and phenobarbital
-
Innocenti F, Undevia SD, Ramirez J, Mani S, Schilsky RL, Vogelzang NJ, Prado M, Ratain MJ. A phase I trial of pharmacologic modulation of irinotecan with ciclosporine and phenobarbital. Clin Pharmacol Ther 2004; 76: 490-502.
-
(2004)
Clin Pharmacol Ther
, vol.76
, pp. 490-502
-
-
Innocenti, F.1
Undevia, S.D.2
Ramirez, J.3
Mani, S.4
Schilsky, R.L.5
Vogelzang, N.J.6
Prado, M.7
Ratain, M.J.8
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