An efficient separation and method development for the quantifying of two basic impurities of Nicergoline by reversed-phase high performance liquid chromatography using ion-pairing counter ions

Journal of Pharmaceutical and Biomedical Analysis

Volumn 42, Issue 4, 2006, Pages 434-440

  Yalçin, Güler ^a   Yüktaş, F Nüray ^a  

^a MARMARA UNIVERSITY   (Turkey)

Author keywords

Basic impurities; Ion pairing counter ions; Nicergoline; Quantification; Reversed phase HPLC

Indexed keywords

1 OCTANESULFONIC ACID SODIUM SALT; 10 METHOXY 1,6 DIMETHYLERGOLINE 8BETA METHANOL 5 CHLORO 3 PYRIDINECARBOXYLATE; 10 METHOXY 6 METHYLERGOLINE 8BETA METHANOL 5 BROMO 3 PYRIDINECARBOXYLATE; AMMONIUM ACETATE; NICERGOLINE; SULFONIC ACID DERIVATIVE; TETRABUTYLAMMONIUM; UNCLASSIFIED DRUG;

ANION EXCHANGE; ARTICLE; CONCENTRATION (PARAMETERS); DIODE; DRUG PURITY; DRUG STRUCTURE; FLOW RATE; PRIORITY JOURNAL; QUANTITATIVE ASSAY; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

ALKANESULFONIC ACIDS; ANION EXCHANGE RESINS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG CONTAMINATION; NICERGOLINE; QUATERNARY AMMONIUM COMPOUNDS; REPRODUCIBILITY OF RESULTS; VASODILATOR AGENTS;

EID: 33748713116     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2006.04.032     Document Type: Article

References (32)

1. Fujihara M., Hirakoso K., Takahashi M., Nakamura T., and Harigaya S. Oyo Yakuri-Pharmacometrics 32 (1986) 31-48
2. Flieger M., Cerny A., Rehacek Z., Sedmera P., Stuchlik J., and Vokoun J. J. Chromatogr. 284 (1984) 219-225
3. Shintomi K., Yoshimoto K., Ogawa Y., Itakura T., Ikezawa K., Narita H., Ishizuka T., Yamaguchi I., and Yamada K. J. Pharmacobiodyn. 10 (1987) 35-48
4. Arcari G., Bernardi L., Bosisio S., Coda G., Fragman G.B., and Glasser H.A. Experientia 28 (1972) 819-820
5. Brossi A. The Alkoloids Chemistry and Pharmacology vol. 38 (1990), Academic Press Inc., San Diego p. 142
6. Tanaka M., Hirai S., Okamoto K., and Yoshida T. Neurosci. Lett. 248 (1998) 68-72
7. Banno K., Horimoto S., and Mabuchi M. J. Chromatogr. 568 (1991) 375-384
8. Banno K., Matsuoka M., and Takahashi R. Chromatographia 32 (1991) 179-181
9. Banno K., and Horimoto S. Chromatographia 31 (1991) 50-54
10. Ahmad A.K.S., Kawy M.A., and Nebsen M. J. Pharm. Biomed. Anal. 30 (2002) 479-489
11. Vervoort R.J.M., Maris F.A., and Hindriks H. J. Chromatogr. 623 (1992) 207-220
12. Vervoort R.J., Ruyter E., Debets A.J., Claessens H.A., Cramers C.A., and de Jong G.J. J. Chromatogr. A 964 (2002) 67-76
13. Vervoort R.J., Ruyter E., Debets A.J., Claessens H.A., Cramers C.A., and de Jong G.J. J. Chromatogr. A 931 (2001) 67-76
14. Nahum A., and Horvath C. J. Chromatogr. 203 (1981) 53-63
15. McCalley D.V. J. Chromatogr. 708 (1995) 185-194
16. De Schutter J.A., and De Moerloose P. J. Chromatogr. 437 (1988) 83-95
17. Helboe P. J. Chromatogr. 523 (1990) 217-225
18. Riley C.M. Xenobiotica 17 (1987) 365-383
19. De Schutter J.A., Van Den Bossche W., and De Moerloose P. J. Pharm. Biomed. Anal. 5 (1987) 559-576
20. Yang X., Dai J., and Carr P.W. Anal. Chem. 75 (2003) 3153-3160
21. Dai J., Yang X., and Carr P.W. J. Chromatogr. A 1005 (2003) 63-82
22. Yang X., Dai J., and Carr P.W. J. Chromatogr. A 996 (2003) 13-31
23. Tomlinson E., Jefferies T.M., and Riley C.M. J. Chromatogr. 159 (1978) 315-358
24. Bidlingmeyer B.A., Deming S.N., Price W.P., Sachok J.B., and Petrusek M. J. Chromatogr. 186 (1979) 419-434
25. Knox J.H., and Hartwick R.A. J. Chromatogr. 204 (1981) 3-21
26. LoBrutto R., Jones A., and Kazakevich Y.V. J. Chromatogr. A 913 (2001) 189-196
27. LoBrutto R., Jones A., Kazakevich Y.V., and McNair H.M. J. Chromatogr. A 913 (2001) 173-187
28. Jones A., LoBrutto R., and Kazakevich Y. J. Chromatogr. A 964 (2002) 179-187
29. Roberts J.M., Diaz A.R., Fortin D.T., Friedle J.M., and Piper S.D. Anal. Chem. 74 (2002) 4927-4932
30. Ari{dotless}öz F., Yalçi{dotless}n G., and Dölen E. Chromatographia 49 (1999) 562-566
31. Macka M., and Borak J. J. Chromatogr. 641 (1993) 101-113
32. Li X., and Fritz J.S. Anal. Chem. 68 (1996) 4481-4488