Association of TNFSF11 gene promoter polymorphisms with bone mineral density in postmenopausal women

Maturitas

Volumn 55, Issue 3, 2006, Pages 219-226

  Mencej, Simona ^a   Preželj, Janez ^b   Kocijančič, Andreja ^b   Ostanek, Barbara ^a   Marc, Janja ^a  

^a UNIVERSITY OF LJUBLJANA   (Slovenia)

^b UNIVERSITY MEDICAL CENTRE LJUBLJANA   (Slovenia)

Author keywords

Bone mineral density; Osteoporosis; RANKL; Single nucleotide polymorphism; TNFSF11 gene

Indexed keywords

OSTEOCLAST DIFFERENTIATION FACTOR;

ADULT; AGED; ARTICLE; BONE DENSITY; BONE MINERAL; CONTROLLED STUDY; DNA SEQUENCE; FEMALE; FEMUR NECK; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC SCREENING; GENETIC VARIABILITY; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; NUCLEOTIDE SEQUENCE; OSTEOLYSIS; POSTMENOPAUSE OSTEOPOROSIS; PROMOTER REGION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SLOVENIA; STATISTICAL SIGNIFICANCE; TNF SUPERFAMILY MEMBER 11 GENE;

AGED; BONE DENSITY; FEMALE; HUMANS; MIDDLE AGED; OSTEOPOROSIS, POSTMENOPAUSAL; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE NUCLEOTIDE; PROMOTER REGIONS (GENETICS); PROMOTER REGIONS, GENETIC; RANK LIGAND;

EID: 33748710617     PISSN: 03785122     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.maturitas.2006.03.004     Document Type: Article

References (21)

1. Hofbauer L.C., and Heufelder A.E. Role of receptor activator of nuclear factor-B ligand and osteoprotegrin in bone cell biology. J Mol Med 79 (2001) 243-253
2. Miyamoto T., and Suda T. Differentiation and function of osteoclasts. Keio J Med 52 1 (2003) 1-7
3. Lacey D.L., Timms E., Tan H.L., et al. Osteoprotegrin ligand is a cytokine that regulates osteoclast differentiation and activation. Cell 93 (1998) 165-176
4. Anderson D.M., Maraskovsky E., Billingsley W.L., et al. A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function. Nature 390 (1997) 175-179
5. Simonet W.S., Lacey D.L., Dunstan C.R., et al. Osteoprotegrin: a novel secreted protein involved in the regulation of bone density. Cell 89 (1997) 309-319
6. Burgess T.L., Qian Y., Kaufman S., et al. The ligand for osteoprotegrin (OPGL) directly activates mature osteoclasts. J Cell Biol 145 (1999) 527-538
7. Fuller K., Wong B., Fox S., Choi Y., and Chambers T.J. TRANCE is necessary and sufficient for osteoblast-mediated activation of bone resorption in osteoclasts. J Exp Med 188 (1998) 997-1001
8. Yasuda H., Shima N., Nakagawa N., et al. Osteoclast differentiation factor is a ligand for osteoprotegrin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL. Proc Natl Acad Sci USA 95 (1998) 3597-3602
9. Kong Y.Y., Yoshida H., Sarosi I., et al. OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis. Nature 397 (1999) 315-323
10. HUGO Gene Nomenclature Committee, Homepage, http://www.gene.ucl.ac.uk/nomenclature/ (accessed April 11, 2005).
11. Kartsogiannis V., Zhou H., Horwood N.J., et al. Localization of RANKL (receptor activator of NKκB ligand) mRNA and protein in skeletal and extraskeletal tissues. Bone 25 (1999) 525-534
12. Walsh M.C., and Choi Y. Biology of TRANCE axis. Cytokine Growth Factor Rev 14 (2003) 251-263
13. Kitazawa R., Kitazawa S., and Maeda S. Promoter structure of mouse RANKL/TRANCE/OPGL/ODF gene. Biochem Biophys Acta 1445 (1999) 134-141
14. O'Brien C.A., Kern B., Gubrij I., Karsenty G., and Manolagas S.C. Cbfa1 does not regulate RANKL gene activity in stromal/osteoblastic cells. Bone 30 (2002) 453-462
15. Roccisana J.L., Kawanabe N., Kajiya H., Koide M., Roodman G.D., and Reddy S.V. Functional role for heat shock factors in the transcriptional regulation of human RANK ligand gene expression in stromal/osteoblast cells. J Biol Chem 12 (2004) 10500-10507
16. Fazzalari N.L., Kuliwaba J.S., Atkins G.J., Forwood M.R., and Findlay D.M. The ratio of messenger RNA levels of receptor activator of nuclear factor κB ligand to osteoprotegrin correlates with bone remodeling indices in normal human cancellous bone but not in osteoarthritis. J Bone Miner Res 16 (2001) 1015-1027
17. Tsangri H., Findlay D.M., Kuliwaba J.S., Atkins G.J., and Fazzalari N.L. Increased expression of IL-6 and RANK mRNA in human trabecular bone from fragility fracture of femoral neck. Bone 35 (2004) 334-342
18. Walker S., Finch M.B., Marsh D., and Li G. In postmenopausal women, femoral neck BMD is positively correlated to circulating levels of soluble RANKL and negatively correlated to levels of IL-7. J Bone Miner Res 19 Suppl 1 (2004) M397
19. Miller S.A., Dykes D.D., and Polesky H.F. A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acid Res 16 (1988) 1215
20. Hsu Y., Niu T., Terwedow H., et al. Variation in genes involved in the RANKL/RANK/OPG bone remodelling pathway are associated with bone mineral density at different skeletal sites in men. Hum Genet 118 (2006) 568-577
21. Kitazawa S., and Kitazawa R. Epigenetic control of mouse receptor activator of NF-κB ligand gene expression. Biochem Biophys Res Commun 290 (2002) 650-655