A dose-response study on the estrogenic activity of benzophenone-2 on various endpoints in the serum, pituitary and uterus of female rats

Archives of Toxicology

Volumn 80, Issue 10, 2006, Pages 656-661

  Schlecht, Christiane ^a   Klammer, Holger ^a   Wuttke, Wolfgang ^a   Jarry, Hubertus ^a  

^a UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

2,2 ,4,4 tetrahydroxybenzophenone; Benchmark approach; BP2; Estradiol; Estrogen receptor; Multi organic risk assessment; Rat

Indexed keywords

BENZOPHENONE DERIVATIVE; CHOLESTEROL; ESTRADIOL VALERATE; HIGH DENSITY LIPOPROTEIN; LEPTIN; LOW DENSITY LIPOPROTEIN; TETRAHYDROXYLBIPHENYLKETONE 2,2',4,4' TETRAHYDROXYBENZOPHENONE; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DOSE RESPONSE; DRUG ACTIVITY; ENDOCRINE FUNCTION; ESTROGEN ACTIVITY; FEMALE; GENE EXPRESSION; HYPOPHYSIS; MARKER GENE; NONHUMAN; OVARIECTOMY; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TRIACYLGLYCEROL BLOOD LEVEL; UROGENITAL SYSTEM; UTERUS;

ANIMALS; BENZOPHENONES; COMPLEMENT C3; DOSE-RESPONSE RELATIONSHIP, DRUG; ESTROGEN RECEPTOR BETA; ESTROGENS; FEMALE; GENE EXPRESSION REGULATION; GLYCOPROTEIN HORMONES, ALPHA SUBUNIT; HUMANS; INSULIN-LIKE GROWTH FACTOR I; LEPTIN; LIPIDS; LIVER; LUTEINIZING HORMONE, BETA SUBUNIT; NO-OBSERVED-ADVERSE-EFFECT LEVEL; ORGAN SIZE; OVARIECTOMY; PITUITARY GLAND; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ESTROGEN; RISK ASSESSMENT; RNA, MESSENGER; SUNSCREENING AGENTS; UTERUS;

EID: 33748691174     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00204-006-0085-1     Document Type: Article

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