Gene expression of ornithine decarboxylase in lung cancers and its clinical significance

Acta Biochimica et Biophysica Sinica

Volumn 38, Issue 9, 2006, Pages 639-645

  Tian, Hui ^a   Huang, Qing ^a   Li, Lin ^a   Liu, Xian Xi ^b   Zhang, Yan ^b  

^a SHANDONG UNIVERSITY   (China)

^b SHANDONG UNIVERSITY   (China)

Author keywords

A 549 cell line; Lung neoplasm; Ornithine decarboxylase; Polyamine biosynthesis

Indexed keywords

ORNITHINE DECARBOXYLASE; TUMOR PROTEIN;

ANIMAL; ARTICLE; BAGG ALBINO MOUSE; ENZYMOLOGY; GENE EXPRESSION; GENE SILENCING; GENE TARGETING; GENE THERAPY; GENETICS; LUNG TUMOR; MALE; METABOLISM; METHODOLOGY; MOUSE; TREATMENT OUTCOME;

ANIMALS; GENE EXPRESSION; GENE SILENCING; GENE TARGETING; GENE THERAPY; LUNG NEOPLASMS; MALE; MICE; MICE, INBRED BALB C; NEOPLASM PROTEINS; ORNITHINE DECARBOXYLASE; TREATMENT OUTCOME;

ADENOVIRIDAE; CYTOMEGALOVIRUS; MUS MUSCULUS;

EID: 33748690512     PISSN: 16729145     EISSN: 17457270     Source Type: Journal    
DOI: 10.1111/j.1745-7270.2006.00204.x     Document Type: Article

References (29)

1. Auvinen M, Paasinen A, Andersson LC, Holtta B. Ornithine decarboxylase activity is critical for cell transformation. Nature 1992, 360: 355-358
2. Moshier JA, Dosescu J, Skunca M, Luk GD. Transformation of NIH/3T3 cells by ornithine decarboxylase overexpression. Cancer Res 1993, 53: 2618-2622
3. Pegg AE, Xiong H, Feith D.I, Shantz LM. S-adenosylmethionine decarboxylase: Structure, function and regulation by polyamines. Biochem Soc Trans 1998, 26: 580-586
4. Marton LJ, Pegg AE. Polyamines as targets for therapeutic intervention. Annu Rev Pharmacol Toxicol 1995, 35: 55-91
5. Moshier JA, Gilbert JD, Skunca M, Dosescu J, Almodovar KM, Luk GD. Isolation and expression of a human ornithine decarboxylase gene. J Biol Chem 1990, 265: 4884-4892
6. Pegg AE, Madhubala R, Kameji T, Bergeron RJ. Control of ornithine decarboxylase activity in α-difluoromethylornithine-resistant L1210 cells by polyamines and synthetic analogues. J Biol Chem 1988, 263: 11008-11014
7. Sistonen L Holtta E, Lehvaslaiho H, Lehtola L, Alitalo K Activation of the neu tyrosine kinase induces the fos/jun transcription factor complex, the glucose transporter and ornithine decarboxylase. J Cell Biol 1989, 109: 1911-1919
8. Auvinen M, Paasinen A, Andersson LC, Holtta E. Ornithine decarboxylase activity is critical for cell transformation. Nature 1992, 360: 355-358
9. Devens BH, Weeks RS, Burns MR, Carlson CL, Brawer MK. Polyamine depletion therapy in prostate cancer. Prostate Cancer Prostatic Dis 2000, 3: 275-279
10. Glikman P, Vegh I, Pollina MA, Mosto AH, Levy CM. Ornithine decarboxylase activity, prolactin blood levels, and estradiol and progesterone receptors in human breast cancer. Cancer 1987, 60: 2237-2243
11. Upp JR Jr, Saydjari R, Townsend CM Jr, Singh P, Barranco SC, Thompson JC. Polyamine levels and gastrin receptors in colon cancers. Ann Surg 1988. 207: 662-669
12. Love RR, Astrow SH, Cheeks AM, Havighurst TC. Ornithine decarboxylase (ODC) as a prognostic factor in operable breast cancer. Breast Cancer Res Treat 2003, 79: 329-334
13. Umemoto S. Antiturnor effect of of α-difluoromethylornithine (DFMO) changes in ornithine decarboxylase (ODC) activity and polyamine (PA) levels in human tumor transplanted into nude mice. Nippon Geka Gakkai Zasshi 1989, 90: 650-660
14. Zagaja GP, Shrivastav M, Fleig MJ, Marton LJ, Rinker-Schaeffer CW, Dolan ME. Effects of polyamine analogues on prostatic adenocarcinoma cells in vitro and in vivo. Cancer Chemother Pharmacol 1998, 41: 505-512
15. Guan J, Fan M, Cao S. Reversion of malignant phenotypes of human lung squamous carcinoma cells by ornithine decarboxylase antisense RNA. Zhonghua Zhong Liu Za Zhi 1996, 18: 81-83
16. Meager A. Gene Therapy Technologies, Applications and Regulations. Hoboken: John Wiley & Sons, 1999
17. Tian H, Li L, Liu XX, Zhang Y. Antitumor effect of antisense ornithine decarboxylase adenovirus on human lung cancer cells. Acta Biochim Biophys Sin 2006, 38:410-416
18. Rockwell SC, Kallman RF, FajardoLF. Characteristics of a serially transplanted mouse mammary tumor and its tissue-culture-adapted derivative. J Natl Cancer Inst. 1972, 49: 735-749
19. Guo LX, Zou K, Ju JH, Xie H. Hyaluronan promotes tumor lymphangiogenesis and intralymphantic tumor growth in xenografts. Acta Biochim Biophys Sin 2005, 37: 601-606
20. Lu SD. Modern molecular biology experimental technique. Beijing: Beijing Higher Education Press 2001
21. Auvinen M, Laine A, Paasinen-Sohns A, Kangas A, Kangas L, Saksela O, Andersson LC et al. Human ornithine decarboxylase-overproducing NIH3T3 cells induce rapidly growing, highly vascularized tumors in nude mice. Cancer Res 1997, 57: 3016-3025
22. Metcalf B, Bey P, Danzin C, Jung M, Casara P, Vevert J. Catalytic irreversible inhibition of mammalian ornithine decarboxylase by substrate and product analogues. J Am Chem Soc 1978, 100: 2551-2553
23. Schipper RG, Deli G, Deloyer P, Lange WP, Schalken JA, Verhofstad AA. Antitumor activity of the polyamine analog N′,N″-diethylnorspennine against human prostate carcinoma cells. Prostate 2000, 44: 313-321
24. Alm K, Berntsson PS, Kramer DL, Porter CW, Oredsson SM. Treatment of cells with the polyamine analog N′,N″-diethylnorspermine retards S phase progression within one cell cycle. Eur J Biochem 2000, 267: 4157-4164
25. Madhubala R, Pegg AE. Inhibition of ornithine decarboxylase and S-adenosyl-methionine decarboxylase synthesis by antisense oligodeoxynucleotides. Mol Cell Biochem 1992, 118: 191-195
26. Thomas T, Kiang DT. Additive growth-inhibitory effects of DL-α-difluoromethyloraithine and antiestrogens on MCF-7 breast cancer cell line. Biochem Biophys Res Commun 1987, 148: 1338-1345
27. Wolter F, Ulrich S, Stein J. Molecular mechanisms of the chemopreventive effects of resveratrol and its analogs in colorectal cancer: Key role of polyamine s. J Nutr 2004, 134:3219-3222
28. Subhi AL, Tang B, Balsara BR, Altomare DA, Testa JR, Cooper HS, Hoffman JP et al. Loss of methylthioadenosine phosphorylase and elevated ornithine decarboxylase is common in pancreatic cancer. Clin Cancer Res 2004, 10: 7290-7296
29. Belting M, Borsig L, Fuster MM, Brown JR, Persson L, Fransson LA, Esko JD. Tumor attenuation by combined heparan sulfate and polyamine depletion. Proc Natl Acad Sci USA 2005, 99: 371-376