Antitumor effect of antisense ornithine decarboxylase adenovirus on human lung cancer cells

Acta Biochimica et Biophysica Sinica

Volumn 38, Issue 6, 2006, Pages 410-416

  Tian, Hui ^a   Li, Lin ^a   Liu, Xian Xi ^b   Zhang, Yan ^b  

^a SHANDONG UNIVERSITY   (China)

^b SHANDONG UNIVERSITY   (China)

Author keywords

A 549 lung cancer cell line; Antisense technology; Biosynthesis; Gene therapy; Polyamine; Putrescine

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; BIOTIN; ORNITHINE DECARBOXYLASE; TETRAZOLIUM; THIAZOLE DERIVATIVE; THIAZOLYL BLUE;

ADENOVIRUS; APOPTOSIS; ARTICLE; CANCER INVASION; CELL PROLIFERATION; CHEMISTRY; GENE THERAPY; GENE TRANSFER; GENETICS; HUMAN; LUNG TUMOR; METABOLISM; METHODOLOGY; NICK END LABELING; TUMOR CELL LINE;

ADENOVIRIDAE; APOPTOSIS; BIOTIN; CELL LINE, TUMOR; CELL PROLIFERATION; GENE THERAPY; GENE TRANSFER TECHNIQUES; HUMANS; IN SITU NICK-END LABELING; LUNG NEOPLASMS; NEOPLASM INVASIVENESS; OLIGONUCLEOTIDES, ANTISENSE; ORNITHINE DECARBOXYLASE; TETRAZOLIUM SALTS; THIAZOLES;

ADENOVIRIDAE;

EID: 33745174114     PISSN: 16729145     EISSN: 17457270     Source Type: Journal    
DOI: 10.1111/j.1745-7270.2006.00176.x     Document Type: Article

References (31)

1. Auvinen M Paasinen A Andersson LC Holtta E. Ornithine decarboxylase activity is critical for cell transformation. Nature 1992, 360 : 355 358.
2. Moshier JA Dosescu J Skunca M Luk GD. Transformation of NIH/3T3 cells by ornithine decarboxylase overexpression. Cancer Res 1993, 53 : 2618 2622.
3. Pegg AE Xiong H Feith DJ Shantz LM. S-adenosylmethionine decarboxylase:structure, function and regulation by polyamines. Biochem Soc Trans 1998, 26 : 580 586.
4. Marton LJ Pegg AE. Polyamines as targets for therapeutic intervention. Annu Rev Pharmacol Toxicol 1995, 35 : 55 91.
5. Moshier JA Gilbert JD Skunca M Dosescu J Almodovar KM Luk GD. Isolation and expression of a human ornithine decarboxylase gene. J Biol Chem 1990, 265 : 4884 4892.
6. Pegg AE Madhubala R Kameji T Bergeron RJ. Control of ornithine decarboxylase activity in α-difluoromethylornithine-resistant L1210 cells by polyamines and synthetic analogues. J Biol Chem 1988, 263 : 11008 11014.
7. Sistonen L Holtta E Lehvaslaiho H Lehtola L Alitalo K. Activation of the neu tyrosine kinase induces the fos/jun transcription factor complex, the glucose transporter and ornithine decarboxylase. J Cell Biol 1989, 109 : 1911 1919.
8. Devens BH Weeks RS Burns MR Carlson CL Brawer MK. Polyamine depletion therapy in prostate cancer. Prostate Cancer Prostatic Dis 2003, 3 : 275 279.
9. Glikman P Vegh I Pollina MA Mosto AH Levy CM. Ornithine decarboxylase activity, prolactin blood levels, and estradiol and progesterone receptors in human breast cancer. Cancer 1987, 60 : 2237 2243.
10. Upp JR Saydjari R Townsend CM Jr. Singh P Barranco SC Thompson JC. Polyamine levels and gastrin receptors in colon cancers. Ann Surg 1988, 207 : 662 669.
11. Love RR Astrow SH Cheeks AM Havighurst TC. Ornithine decarboxylase (ODC) as a prognostic factor in operable breast cancer. Breast Cancer Res Treat 2003, 79 : 329 334.
12. Umemoto S. Antitumor effect of alpha-difluoromethylornithine (DFMO) changes in ornithine decarboxylase (ODC) activity and polyamine (PA) levels in human tumor transplanted into nude mice. Nippon Geka Gakkai Zasshi 1989, 90 : 650 660.
13. Zagaja GP Shrivastav M Fleig MJ Marton LJ Rinker-Schaeffer CW Dolan ME. Effects of polyamine analogues on prostatic adenocarcinoma cells in vitro and in vivo. Cancer Chemother Pharmacol 1998, 41 : 505 512.
14. Guan J Fan M Cao S. Reversion of malignant phenotypes of human lung squamous carcinoma cells by ornithine decarboxylase antisense RNA. Zhonghua Zhong Liu Za Zhi 1996, 18 : 81 83.
15. Carlisle DL Devereux WL Hacker A Woster PM Casero RA Growth status significantly affects the response of human lung cancer cells to antitumor polyamine-analogue exposure. Clin Cancer Res 2002, 8 : 2684 2689.
16. Meager A. Gene therapy technologies, applications and regulations. Hoboken : John Wiley & Sons Press, 1999.
17. Zhang Y Liu X Hu H Geng Z Wang X Zhang B. Construction of an antisense RNA recombinant adenovirus vector of the third extron in ODC gene. Journal of Shandong University (Health Sciences) 2003, 41 : 371 374.
18. Prevec L Christie BS Laurie KE Bailey MM Graham FL Rosenthal KL. Immune response to HIV-1 gag antigens induced by recombinant adenovirus vectors in mice and rhesus macaque monkeys. J Acquir Immune Defic Syndr 1991, 4 : 568 576.
19. Wei D Tang Z Chen S. Construction of recombinant adenovirus vector containing mIL-12 using the method of homogenous recombination in Bacteria and its expression in vitro with high efficient. Chin J Biochem Mol Biol 2000, 16 : 716 721.
20. Fu S Zou X Wang X Liu X. Determination of polyamine in human prostate by high-performance liquid chromatography with fluorescence detection. J Chromatogr B Biomed Sci Appl 1998, 709 : 297 300.
21. Auvinen M Laine A Paasinen-Sohns A Kangas A Kangas L Saksela O Andersson LC et al. Human ornithine decarboxylase-overproducing NIH3T3 cells induce rapidly growing, highly vascularized tumors in nude mice. Cancer Res 1997, 57 : 3016 3025.
22. Metcalf B Bey P Danzin C Jung M Casara P Vevert J. Catalytic irreversible inhibition of mammalian ornithine decarboxylase by substrate and product analogues. J Am Chem Soc 1978, 100 : 2551 2553.
23. Schipper RG Deli G Deloyer P Lange WP Schalken JA Verhofstad AA. Antitumor activity of the polyamine analog N(1),N(11)-diethylnorspermine against human prostate carcinoma cells. Prostate 2000, 44 : 313 321.
24. Alm K Berntsson PS Kramer DL Porter CW Oredsson SM. Treatment of cells with the polyamine analog N,N11-diethylnorspermine retards S phase progression within one cell cycle. Eur J Biochem 2000, 267 : 4157 4164.
25. Weeks RS Vanderwerf SM Carlson CL Burns MR O'Day CL Cai F Devens BH et al. Novel lysine-spermine conjugate inhibits polyamine transport and inhibits cell growth when given with DFMO. Exp Cell Res 2000, 261 : 293 302.
26. Love RR Astrow SH Cheeks AM. Ornithine decarboxylase (ODC) as a prognostic factor in operable breast cancer. Breast Cancer Res Treat 2003, 79 : 329 334.
27. Wolter F Ulrich S Stein J. Molecular mechanisms of the chemopreventive effects of resveratrol and its analogs in colorectal cancer: key role of polyamines. J Nutr 2004, 134 : 3219 3222.
28. Subhi AL Tang B Balsara BR Altomare DA Testa JR Cooper HS Hoffman JP et al. Loss of methylthioadenosine phosphorylase and elevated ornithine decarboxylase is common in pancreatic cancer. Clin Cancer Res 2004, 10 : 7290 7296.
29. Seiler N Raul F. Polyamines and apoptosis. J Cell Mol Med 2005, 9 : 623 642.
30. Stanic I Facchini A Borzí RM Vitellozzi R Stefanelli C Goldring MB Guarnieri C et al. Polyamine depletion inhibits apoptosis following blocking of survival pathways in human chondrocytes stimulated by tumor necrosis factor-α. J Cell Physiol 2006, 206 : 138 146.
31. Feith DJ Bol DK Carboni JM Lynch MJ Sass-Kuhn S Shoop PL Shantz LM. Induction of ornithine decarboxylase activity is a necessary step for mitogen-activated protein kinase kinase-induced skin tumorigenesis. Cancer Res 2005, 65 : 572 578.